KEGG   DISEASE: Generalized anxiety disorder
Entry
H01662                      Disease                                

Name
Generalized anxiety disorder;
Anxiety neurosis
Description
Generalized anxiety disorder is a persistent and common mental disorder. This disorder is twice as common in women than it is in men. The symptoms include generalised and persistent excessive anxiety and a combination of various psychological and somatic complaints, such as threat, restlessness, irritability, sleep disturbance, tension, palpitations, dry mouth, and sweating. The symptoms overlap greatly with those of other mental disorders and we could regard the disorder as part of a spectrum of mood and related disorders rather than an independent disorder. Generalized anxiety disorder has a relapsing course, and intervention rarely results in complete resolution of symptoms. But in the short term and medium term, effective treatments include psychological therapies, such as cognitive behavioural therapy, and pharmacological treatments, mainly selective serotonin reuptake inhibitors (SSRIs).
Category
Mental and behavioural disorder
Brite
Human diseases [BR:br08402]
 Other diseases
  Mental and behavioural disorders
   H01662  Generalized anxiety disorder
Human diseases in ICD-11 classification [BR:br08403]
 06 Mental, behavioural or neurodevelopmental disorders
  Anxiety or fear-related disorders
   6B00  Generalised anxiety disorder
    H01662  Generalized anxiety disorder
Drug
Phenobarbital sodium [DR:D00701]
Diazepam [DR:D00293]
Clorazepate dipotassium [DR:D00694]
Alprazolam [DR:D00225]
Buspirone hydrochloride [DR:D00702]
Paroxetine hydrochloride [DR:D05374]
Paroxetine mesylate [DR:D05375]
Escitalopram oxalate [DR:D02567]
Venlafaxine hydrochloride [DR:D00821]
Duloxetine hydrochloride [DR:D01179]
Perphenazine and amitriptyline hydrochloride [DR:D10294]
Other DBs
ICD-11: 6B00
ICD-10: F41.1
MeSH: D001008
Reference
  Authors
Tyrer P, Baldwin D
  Title
Generalised anxiety disorder.
  Journal
Lancet 368:2156-66 (2006)
DOI:10.1016/S0140-6736(06)69865-6
Reference
PMID:24326166 (drug)
  Authors
Chollet J, Saragoussi D, Clay E, Francois C
  Title
A clinical research practice datalink analysis of antidepressant treatment patterns and health care costs in generalized anxiety disorder.
  Journal
Value Health 16:1133-9 (2013)
DOI:10.1016/j.jval.2013.09.001

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