Entry Name dTDP-4-dehydrorhamnose reductase;
Class Oxidoreductases;BRITE hierarchy
Sysname dTDP-beta-L-rhamnose:NADP+ 4-oxidoreductase
Reaction(IUBMB) dTDP-beta-L-rhamnose + NADP+ = dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ [RN:
R02777 ]
Reaction(KEGG) Substrate Product Comment In the reverse direction, reduction on the 4-position of the hexose moiety takes place only while the substrate is bound to another enzyme that catalyses epimerization at C-3 and C-5; the complex has been referred to as dTDP-L-rhamnose synthase.
History EC 1.1.1.133 created 1972
Pathway ec00523 Polyketide sugar unit biosynthesis
ec00541 O-Antigen nucleotide sugar biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology K00067 dTDP-4-dehydrorhamnose reductase
K23987 dTDP-4-dehydrorhamnose 3,5-epimerase/reductase
Genes ECW : EcE24377A_2331(rfbD)
EDJ : ECDH1ME8569_1977(rfbD)
ECOI : ECOPMV1_02194(rfbD)
KPN : KPN_02489(rmlD) KPN_02495(rmlD)
RTG : NCTC13098_02332(rfbD_1)
REE : electrica_01674(rfbD_1)
CIE : AN232_13700 AN232_31130
CLAP : NCTC11466_01512(rfbD)
KIE : NCTC12125_00620(rfbD)
LAX : APT61_07765 APT61_19445
LEI : C2U54_07865 C2U54_19805
LEH : C3F35_08825 C3F35_19915
LER : GNG29_03090(rfbD) GNG29_14880(rfbD)
LEA : GNG26_02700(rfbD) GNG26_14725(rfbD)
PSHI : SAMEA2665130_0124(rfbD)
SFW : WN53_17260 WN53_17285
SERA : Ser39006_021665(rfbD)
SFJ : SAMEA4384070_1627(rfbD)
RACE : JHW33_02970(rfbD) JHW33_12185(rfbD)
GQU : AWC35_04155 AWC35_04210
PPUJ : E2566_07220 E2566_07240(rfbD)
PAQU : DMB82_0013770(rfbD)
DIC : Dpoa569_002475(rfbD) Dpoa569_003267(rfbD)
EPE : CI789_04075 CI789_06130(rfbD)
PLF : PANA5342_1595(rmlD) PANA5342_1836
PAQ : PAGR_g1539 PAGR_g1770
TPTY : NCTC11468_00807(rfbD_1)
LPV : HYN51_14540 HYN51_14600(rfbD)
ALIG : NCTC10568_01751(rfbD)
AVT : NCTC3438_00463(rfbD)
