KEGG   ORTHOLOGY: K00157
Entry
K00157                      KO                                     

Symbol
AOX
Name
aldehyde oxidase [EC:1.2.3.1]
Pathway
map00280  Valine, leucine and isoleucine degradation
map00350  Tyrosine metabolism
map00380  Tryptophan metabolism
map00750  Vitamin B6 metabolism
map00760  Nicotinate and nicotinamide metabolism
map00830  Retinol metabolism
map00982  Drug metabolism - cytochrome P450
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K00157  AOX; aldehyde oxidase
   00350 Tyrosine metabolism
    K00157  AOX; aldehyde oxidase
   00380 Tryptophan metabolism
    K00157  AOX; aldehyde oxidase
  09108 Metabolism of cofactors and vitamins
   00750 Vitamin B6 metabolism
    K00157  AOX; aldehyde oxidase
   00760 Nicotinate and nicotinamide metabolism
    K00157  AOX; aldehyde oxidase
   00830 Retinol metabolism
    K00157  AOX; aldehyde oxidase
  09111 Xenobiotics biodegradation and metabolism
   00982 Drug metabolism - cytochrome P450
    K00157  AOX; aldehyde oxidase
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K00157  AOX; aldehyde oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.3  With oxygen as acceptor
    1.2.3.1  aldehyde oxidase
     K00157  AOX; aldehyde oxidase
Other DBs
RN: R01709 R02125 R02657 R03871 R04085 R04904 R08349 R08384 R08408
GO: 0004031
Genes
HSA: 316(AOX1)
PTR: 459863(AOX1) 747025
PPS: 100968717(AOX1)
GGO: 101125522(AOX1) 115933782
PON: 100451794(AOX4) 100939468(AOX1)
NLE: 100583419 100583754(AOX1)
MCC: 701024(AOX1) 701502(AOX4) 701613(AOX2)
MCF: 102131116(AOX1) 102134468(AOX2) 102134825(AOX4)
CSAB: 103217611 103217617 103217619
CATY: 105580017 105580021 105580200
PANU: 101001006(AOX1) 101002286(AOX4) 101002632(AOX2)
CJC: 100393665(AOX1) 100394388(AOX2)
MMU: 11761(Aox1) 213043(Aox2) 71724(Aox3) 71872(Aox4)
RNO: 316421(Aox2) 316424(Aox4) 493909(Aox3) 54349(Aox1)
HGL: 101710340 101722324(Aox4) 101722898(Aox1)
OCU: 100008601(AOX1) 100345417(AOX2) 100345675(AOX3) 100354428(AOX4)
CFA: 488467(AOX4) 608849(AOX2)
AML: 100470835(AOX4) 100471086(AOX2) 100474367(AOX1)
FCA: 101085487(AOX1)
PYU: 121030893
PBG: 122481631
PTG: 102949513(AOX1) 102967431
PPAD: 109254456
AJU: 106979979(AOX1)
HHV: 120220681(AOX1)
BTA: 338074(AOX1) 518393(AOX4) 531699(AOX2)
CHX: 102171556 102187632(AOX1) 102188176(AOX1)
SSC: 100523701(AOX1) 100525616(AOX2) 100623394(AOX4)
OOR: 101285123(AOX1)
DLE: 111171714
PCAD: 102987494 102992680(AOX1)
EPZ: 103541147(AOX1) 103543311
MYB: 102249846 102257951(AOX1)
MYD: 102755298(AOX1) 102771691
MMYO: 118661030(AOX1) 118661465
DRO: 112307752
SHON: 118985255 118985256(AOX1)
MDO: 100016433(AOX2) 100029977(AOX1) 100030014(AOX4) 107648868
OAA: 100092481(AOX1)
GGA: 424071(AOX1) 424072(AOX2)
MGP: 100548803(AOX1) 100549268
CJO: 107316537(AOX1)
NMEL: 110400687(AOX1)
APLA: 101795737(AOX1)
ACYG: 106039970(AOX1)
TGU: 100217503(AOX1)
LSR: 110484579(AOX1)
SCAN: 103814515(AOX1)
PMOA: 120496991(AOX1)
OTC: 121335283(AOX1)
PRUF: 121356479(AOX1)
GFR: 102031924(AOX1)
FAB: 101818190(AOX1)
PHI: 102105114(AOX1)
PMAJ: 107207425
CCAE: 111931979(AOX1)
CCW: 104693769(AOX1)
ETL: 114055687 114055700(AOX1)
FPG: 101915658(AOX1)
FCH: 102057814(AOX1)
CLV: 102097486(AOX1)
EGZ: 104130522
NNI: 104010254(AOX1)
ACUN: 113480959
PADL: 103923316(AOX1)
DNE: 112985928(AOX1) 112986459
PSS: 102452808(AOX1) 102453236
CPIC: 101949109 101949373(AOX1)
TST: 117885114
PVT: 110089018 110089019(AOX1)
PBI: 103048615(AOX1)
PMUR: 107291766(AOX1)
PGUT: 117673209(AOX1)
PMUA: 114607773 114607791(AOX1)
XLA: 108701447 108701448 108701449(aox1.L) 444490(aox1.S)
XTR: 100379890(aox1) 100493336 100495429(aox1)
DRE: 570457(aox6) 64265(aox5)
CCAR: 109060027
CAUA: 113040179 113064802(aox1)
IPU: 108259545
PHYP: 113524277
EEE: 113585478
TRU: 101069055(aox1)
LCO: 104937222(aox1)
ELY: 117249798(aox6)
SLUC: 116048613(aox6)
ECRA: 117939455(aox6)
PFLV: 114550961
GAT: 120825730(aox6)
PPUG: 119219585(aox6)
MSAM: 119905158(aox6)
CUD: 121506461(aox6)
MZE: 101479847(aox1)
ONL: 100708434(aox1)
OAU: 116317008(aox6)
OLA: 101168436(aox1)
OML: 112156643(aox6)
XMA: 102223145(aox1)
XCO: 114140277(aox1)
XHE: 116716236(aox1)
PRET: 103457351(aox1)
CVG: 107082806(aox1)
CTUL: 119791441(aox6)
NFU: 107384677(aox1)
AOCE: 111570749(aox1)
POV: 109639006 109639051(aox1)
LCF: 108873170(aox1)
SLAL: 111670357(aox1)
XGL: 120798313(aox6)
HCQ: 109520227(aox1)
BPEC: 110175588(aox1) 110175628
MALB: 109955752(aox1)
OTW: 112253972(aox6) 112266560(aox5)
OMY: 110495922(aox5) 110527537(aox6)
SNH: 120033102(aox6) 120050454(aox5)
ELS: 105022540(aox1)
PKI: 111856671(aox1)
AANG: 118223618(aox6) 118223619(aox5)
PSPA: 121322943(aox5)
ARUT: 117402944(aox5)
LCM: 102354789(AOX1) 102358967
RTP: 109935677(aox1)
BBEL: 109484006
CEL: CELE_B0222.9(gad-3)
CBR: CBG19218
 » show all
Reference
  Authors
Huang DY, Furukawa A, Ichikawa Y
  Title
Molecular cloning of retinal oxidase/aldehyde oxidase cDNAs from rabbit and mouse livers and functional expression of recombinant mouse retinal oxidase cDNA in Escherichia coli.
  Journal
Arch Biochem Biophys 364:264-72 (1999)
DOI:10.1006/abbi.1999.1129
  Sequence
[mmu:11761] [ocu:100008601]
Reference
  Authors
Garattini E, Fratelli M, Terao M
  Title
The mammalian aldehyde oxidase gene family.
  Journal
Hum Genomics 4:119-30 (2009)
DOI:10.1186/1479-7364-4-2-119
Reference
  Authors
Schmeisser K, Mansfeld J, Kuhlow D, Weimer S, Priebe S, Heiland I, Birringer M, Groth M, Segref A, Kanfi Y, Price NL, Schmeisser S, Schuster S, Pfeiffer AF, Guthke R, Platzer M, Hoppe T, Cohen HY, Zarse K, Sinclair DA, Ristow M
  Title
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.
  Journal
Nat Chem Biol 9:693-700 (2013)
DOI:10.1038/nchembio.1352
  Sequence

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