Entry Name nitronate monooxygenase;
Class Oxidoreductases;BRITE hierarchy
Sysname nitronate:oxygen 2-oxidoreductase (nitrite-forming)
Reaction(IUBMB) ethylnitronate + O2 = acetaldehyde + nitrite + other products [RN:
R00025 ]
Reaction(KEGG) Substrate Product acetaldehyde [CPD:
C00084 ];
nitrite [CPD:
C00088 ];
other products
Comment Previously classified as 2-nitropropane dioxygenase (EC
1.13.11.32 ), but it is now recognized that this was the result of the slow ionization of nitroalkanes to their nitronate (anionic) forms. The enzymes from the fungus Neurospora crassa and the yeast Williopsis saturnus var. mrakii (formerly classified as Hansenula mrakii) contain non-covalently bound FMN as the cofactor. Neither hydrogen peroxide nor superoxide were detected during enzyme turnover. Active towards linear alkyl nitronates of lengths between 2 and 6 carbon atoms and, with lower activity, towards propyl-2-nitronate. The enzyme from N. crassa can also utilize neutral nitroalkanes, but with lower activity.
History EC 1.13.12.16 created 1984 as EC 1.13.11.32, transferred 2009 to EC 1.13.12.16, modified 2011
Pathway Orthology K00459 nitronate monooxygenase
Genes CAL : CAALFM_C703780CA(CaO19.7204)
NTE : NEUTE1DRAFT118227(NEUTE1DRAFT_118227)
PAN : PODANSg09244 PODANSg926
TTT : THITE_2091299 THITE_49067
PPEI : PpBr36_01900 PpBr36_09852
FGR : FGSG_10065 FGSG_12180
FPU : FPSE_00492 FPSE_06497
FVR : FVEG_02709 FVEG_08990
FOX : FOXG_05426 FOXG_10337
NHE : NECHADRAFT_100543 NECHADRAFT_42834 NECHADRAFT_89383
TRE : TRIREDRAFT_123468 TRIREDRAFT_63397
TRR : M419DRAFT_137363 M419DRAFT_9212
PLJ : VFPFJ_08658 VFPFJ_09670
ELA : UCREL1_1620 UCREL1_6782
PFY : PFICI_00047 PFICI_12651
SSL : SS1G_06113 SS1G_10881
BFU : BCIN_04g06240 BCIN_05g03970
GLZ : GLAREA_07467 GLAREA_11804 GLAREA_12226
AFM : AFUA_2G17430 AFUA_7G03850
ACT : ACLA_005550 ACLA_094120
NFI : NFIA_024810 NFIA_045310 NFIA_092830
AOR : AO090003001368 AO090012000044 AO090038000173
ANG : ANI_1_480044(An05g01450) ANI_1_528044(An05g01810)
AFV : AFLA_000310 AFLA_001747 AFLA_003644 AFLA_012436
ALUC : AKAW2_81303A AKAW2_81331A
ACHE : ACHE_40241S ACHE_60585S ACHE_70093S
APUU : APUU_30168S APUU_51008S APUU_60519S APUU_70098S
PCS : Pc16g10070 Pc18g02290 Pc22g11480
TRG : TRUGW13939_02495 TRUGW13939_04053 TRUGW13939_07128 TRUGW13939_11628 TRUGW13939_11987
PNO : SNOG_03020 SNOG_03703 SNOG_14477
AALT : CC77DRAFT_1023703 CC77DRAFT_1034395 CC77DRAFT_854456
ZTR : MYCGRDRAFT_110271 MYCGRDRAFT_70263 MYCGRDRAFT_86766
PFJ : MYCFIDRAFT_189995 MYCFIDRAFT_71718
FFU : CLAFUR5_04989 CLAFUR5_05122
TVS : TRAVEDRAFT_29201 TRAVEDRAFT_37560
PCO : PHACADRAFT_141840 PHACADRAFT_254568 PHACADRAFT_263640
SHS : STEHIDRAFT_100058 STEHIDRAFT_148287
LBC : LACBIDRAFT_191118 LACBIDRAFT_310141
ABP : AGABI1DRAFT105369(AGABI1DRAFT_105369)
ABV : AGABI2DRAFT136944(AGABI2DRAFT_136944)
MRR : Moror_1103 Moror_6912
MORE : E1B28_003369 E1B28_007091 E1B28_007510
SCM : SCHCO_02571870(SCHCODRAFT_02571870)
SLA : SERLADRAFT_384786 SERLADRAFT_451000
XPH : XppCFBP6546_05035(XppCFBP6546P_05035)
XHD : LMG31886_30380(pnoA)
LSOL : GOY17_00660 GOY17_09285
LSX : H8B22_00510 H8B22_00835
RTH : LRK53_07240 LRK53_10650
PMAI : CF386_09315 CF386_09320
PAU : PA14_08460 PA14_09580
PAP : PSPA7_0801 PSPA7_0896
PAG : PLES_06391 PLES_07251
PAF : PAM18_0641 PAM18_0735
PNC : NCGM2_5401 NCGM2_5543
PAEB : NCGM1900_0660 NCGM1900_0757
PDK : PADK2_03225 PADK2_03660
PSG : G655_03255 G655_03695
PRP : M062_03215 M062_22140
PAEP : PA1S_03330 PA1S_03810
PAER : PA1R_gp2093 PA1R_gp4160
PAEM : U769_03360 U769_03840
PAEL : T223_03260 T223_03745
PAES : SCV20265_0672 SCV20265_0760
PAEU : BN889_00747 BN889_04676
PAEG : AI22_00100 AI22_00580
PRE : PCA10_05680 PCA10_26000
PPSE : BN5_0455(fabK) BN5_3734
PFUW : KF707C_27570 KF707C_5320
PALC : A0T30_03940 A0T30_19950
PCQ : PcP3B5_07220 PcP3B5_29400 PcP3B5_30500
PMUI : G4G71_13970 G4G71_29510
PPAA : B7D75_03245 B7D75_03745
PPU : PP_0430 PP_3827(yrpB)
PPG : PputGB1_0460 PputGB1_3542
PPW : PputW619_3196 PputW619_4773
PPB : PPUBIRD1_0467 PPUBIRD1_1953
PPUH : B479_02630 B479_16475
PPUT : L483_02185 L483_21455
PPUN : PP4_04620 PP4_18550
PPUD : DW66_0438 DW66_3738
PMON : X969_00525 X969_15960
PMOT : X970_00515 X970_15605
PMOS : O165_012890 O165_026115
PPJ : RK21_01323 RK21_04587
PMOL : CLJ08_03090 CLJ08_15150
PST : PSPTO_2972 PSPTO_3202
PSP : PSPPH_2163 PSPPH_2406
PSAV : PSA3335_10525 PSA3335_15850
PAMG : BKM19_016590 BKM19_017945
PAVL : BKM03_13075 BKM03_14115
PCAB : JGS08_07195 JGS08_11615
PSYI : MME58_14390 MME58_15630
PLIJ : KQP88_13175 KQP88_19535
PFL : PFL_1474 PFL_3411 PFL_5613
PPRC : PFLCHA0_c15130 PFLCHA0_c34420 PFLCHA0_c55660
PPRO : PPC_1527 PPC_3435 PPC_5559
PFE : PSF113_2302 PSF113_5328
PFN : HZ99_02245 HZ99_14595 HZ99_25140
PFO : Pfl01_2940 Pfl01_5104
PFC : PflA506_2748 PflA506_4855
PTV : AA957_17270 AA957_28930
PCG : AXG94_03775 AXG94_04705 AXG94_12555
PVR : PverR02_14370 PverR02_16310 PverR02_28505
PAZO : AYR47_03920 AYR47_22880
POI : BOP93_12805 BOP93_23510
PRX : HRH33_14315 HRH33_24315
PMED : E3Z27_17025 E3Z27_25560
PFW : PF1751_v1c27520 PF1751_v1c49750
PFF : PFLUOLIPICF711120 PFLUOLIPICF722555
PFX : A7318_13055 A7318_24500
PBA : PSEBR_a3427 PSEBR_a5109
PBC : CD58_11910 CD58_26835
PPUU : PputUW4_02400 PputUW4_04908
PDR : H681_02645 H681_12045 H681_12905
PSV : PVLB_15895 PVLB_23055
PSK : U771_17375 U771_28710
PKC : PKB_2834 PKB_4358 PKB_4771
PCH : EY04_16955 EY04_28320 EY04_32490
PCZ : PCL1606_06740 PCL1606_07780 PCL1606_26560
PCP : JM49_03275 JM49_03945 JM49_13715
PFZ : AV641_02380 AV641_10515
PLQ : AA042_07615 AA042_19745
PALK : PSAKL28_04700 PSAKL28_32720
PPV : NJ69_09665 NJ69_16460
PSEM : TO66_17680 TO66_28305
PSEC : CCOS191_2066 CCOS191_4892
PPSY : AOC04_07815 AOC04_22510
PSOS : POS17_3392 POS17_5553
PKR : AYO71_17720 AYO71_27420
PFK : PFAS1_14120 PFAS1_25205
PANR : A7J50_3036 A7J50_5274
PSIL : PMA3_15980 PMA3_16770 PMA3_27410
PYM : AK972_0384 AK972_3044
PKE : DLD99_15375 DLD99_26055
PALL : UYA_02625 UYA_20975
PUM : HGP31_13545 HGP31_13570 HGP31_16770 HGP31_28355
POJ : PtoMrB4_06370 PtoMrB4_20090
PPSH : G5J76_05325 G5J76_13470
PGY : AWU82_09355 AWU82_12945
PLAL : FXN65_02750 FXN65_13300 FXN65_15085
PSEJ : HNQ25_04735 HNQ25_21515
PVK : EPZ47_11745 EPZ47_26950
PEZ : HWQ56_22805 HWQ56_26050
PBZ : GN234_06495 GN234_21225
PKH : JLK41_02725 JLK41_21810
PTY : JWV26_07000 JWV26_13655
PMAO : PMYSY11_0673 PMYSY11_4083(pnoA)
PATA : JWU58_03485 JWU58_12495
PZE : HU754_013425 HU754_027285
PMOE : HV782_014120 HV782_026375
PCAM : HNE05_16115 HNE05_20375
PSEP : C4K39_4053 C4K39_5383
PVW : HU752_012940 HU752_021625 HU752_029550
PTRT : HU722_0015570 HU722_0026765
PXA : KSS93_05565 KSS93_13955
PSAM : HU731_002115 HU731_012895
PTZ : HU718_014070 HU718_027555
PQI : KH389_10965 KH389_15745 KH389_24460
PSHH : HU773_012815 HU773_025305
PXN : HU772_002305 HU772_010505
PHV : HU739_003420 HU739_026265
PNN : KEM63_00150 KEM63_04640 KEM63_12325
PANH : HU763_002085 HU763_015110
PASG : KSS96_15435 KSS96_25945
PFAK : KSS94_02440 KSS94_11215
PMUY : KSS95_00755 KSS95_13325
PMAM : KSS90_02320 KSS90_16370
PAZE : KSS91_13210 KSS91_26100
PALV : KSS97_11750 KSS97_26280
PPHA : BVH74_04535 BVH74_16460
PORY : EJA05_02370 EJA05_17010
PWZ : J7655_02860 J7655_18540
PTK : EXN22_15960 EXN22_25025
PTW : TUM18999_07800 TUM18999_21770 TUM18999_31860
PZA : HU749_018365 HU749_027055
PIE : HU724_015985 HU724_025510
PTAE : NCTC10697_00487 NCTC10697_02053
PGF : J0G10_17055 J0G10_27895
PCAV : D3880_02635 D3880_03650
PHF : NLY38_02810 NLY38_22140
PIZ : LAB08_R26520 LAB08_R33690 LAB08_R55080
PPEG : KUA23_15660 KUA23_27135
PSII : NF676_14990 NF676_24460
PSIH : LOY51_02405 LOY51_17060
PCAS : LOY40_11240 LOY40_26185
PSJ : PSJM300_02055 PSJM300_03010
PSTT : CH92_02925 CH92_19195
PBB : AKN87_08120 AKN87_08565
HPEG : EAO82_01845 EAO82_03800
HAES : LO767_14550 LO767_16785
HARR : HV822_06805 HV822_08155
MAQ : Maqu_1908 Maqu_3014 Maqu_3902
MARI : ACP86_04705 ACP86_19490
MLQ : ASQ50_06340 ASQ50_19320
MARA : D0851_07865 D0851_12925
PSYC : DABAL43B_0029(fabK)
ABC : ACICU_01387 ACICU_02703
ACAL : BUM88_13960 BUM88_14625
ALA : BFG52_07170 BFG52_10685
ADS : FPL17_00540 FPL17_05020
ATN : FM020_04975 FM020_06425
AGYL : FPL18_11950 FPL18_16635
MBAH : HYN46_04425 HYN46_09395
SPOI : IMCC21906_00674 IMCC21906_02724
SNAN : I6N98_00805 I6N98_04575
STAW : NCG89_06185 NCG89_10495 NCG89_10700
ZAL : AZF00_04020 AZF00_05815 AZF00_06155
KIM : G3T16_07610 G3T16_16365
AFUS : EYZ66_03955 EYZ66_07965
LLG : 44548918_01433(ant1)
PSAL : PSLF89_2354 PSLF89_3158
NAX : HC341_03050 HC341_04315
GAI : IMCC3135_02210 IMCC3135_32435
HAA : A5892_02490 A5892_03305
ALN : AS19_02930 AS19_21780
ADI : B5T_01525 B5T_01859 B5T_03045 B5T_03380 B5T_04157
AXE : P40_07065 P40_14165 P40_15860 P40_20210
APAC : S7S_05825 S7S_18040
MPRI : MP3633_1521 MP3633_3153
MARS : A8C75_14115 A8C75_18715
MGEO : CFI10_06030 CFI10_08965
MSEC : LN244_04495 LN244_08700
MRZ : KDW95_01625 KDW95_07085 KDW95_12365
NCU : F0U83_08990 F0U83_14295
NJP : NEJAP_0039 NEJAP_3189
NIK : F5I99_15430 F5I99_18580
CHJ : NCTC10426_01552 NCTC10426_02319
SDF : ACG33_03955 ACG33_11375
SOK : D0B54_06675 D0B54_08290 D0B54_16320 D0B54_21825 D0B54_22695
SINI : GT972_05960 GT972_11990
FCE : JN531_009175 JN531_014100
ACII : C4901_01345 C4901_16685
ATY : A9R16_001170 A9R16_015055
SALN : SALB1_0584 SALB1_1560 SALB1_2682 SALB1_3724
CDIZ : CEDIAZO_02580(nmoA)
NWE : SAMEA3174300_0273 SAMEA3174300_1221
NSI : A6J88_03380 A6J88_07880
NMJ : NM96_02550 NM96_11585
NZL : D0T92_05805 D0T92_10595
NBL : GJV52_00665 GJV52_01580
