KEGG   ORTHOLOGY: K00496
Entry
K00496                      KO                                     
Symbol
alkB1_2, alkM
Name
alkane 1-monooxygenase [EC:1.14.15.3]
Pathway
map00071  Fatty acid degradation
map00930  Caprolactam degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K00496  alkB1_2, alkM; alkane 1-monooxygenase
  09111 Xenobiotics biodegradation and metabolism
   00930 Caprolactam degradation
    K00496  alkB1_2, alkM; alkane 1-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.3  alkane 1-monooxygenase
     K00496  alkB1_2, alkM; alkane 1-monooxygenase
Other DBs
RN: R01347 R02281 R06945
GO: 0018685 0052869
Genes
PSD: DSC_08960
XBC: ELE36_04735
DTX: ATSB10_28120
VAS: GT360_06145
PAE: PA1525(alkB2) PA2574(alkB1)
PAEV: N297_1567(alkB2) N297_2651(alkB1)
PAEI: N296_1567(alkB2) N296_2651(alkB1)
PAU: PA14_30810(alkB1) PA14_44700(alkB2)
PAP: PSPA7_2642 PSPA7_3808
PAG: PLES_27201(alkB1) PLES_38031(alkB2)
PAF: PAM18_2419(alkB1) PAM18_3523(alkB2)
PNC: NCGM2_2412(alkB2) NCGM2_3586(alkB1)
PAEB: NCGM1900_3944(alkB1) NCGM1900_5055(alkB2)
PAEU: BN889_01620(alkB2) BN889_02835(alkB1)
PAEC: M802_1564(alkB2) M802_2648(alkB1)
PAEO: M801_1566(alkB2) M801_2516(alkB1)
PMK: MDS_1928
PCQ: PcP3B5_23990(alkB2)
PFL: PFL_2935(alkB)
PPRC: PFLCHA0_c29810(alkB1)
PPRO: PPC_2966(alkB)
PFS: PFLU_3535
PFC: PflA506_2496(alkB)
PFB: VO64_0643
PKC: PKB_2028(alkB2)
PSOS: POS17_2902(alkB)
PANR: A7J50_2574
PALL: UYA_14605
POJ: PtoMrB4_19950(alkB2)
PSEP: C4K39_2998
PTW: TUM18999_38450(alkB2)
MHC: MARHY2735(alkM) MARHY2847(alkB)
MAD: HP15_2574(alkB) HP15_2892(alkB)
MBS: MRBBS_1602(alkB1)
MARJ: MARI_02610(alkB) MARI_17900(alkB1)
ACB: A1S_1641
ABM: ABSDF1860(alkM)
ABY: ABAYE2014(alkM)
ABN: AB57_1863
ABB: ABBFA_01834(alkB)
ABX: ABK1_2124
ABH: M3Q_2018
ABAD: ABD1_16260(alkM)
ABAZ: P795_9080
ABAU: IX87_19025
ABAA: IX88_10110
ACC: BDGL_001009(alkM)
ACI: ACIAD1411(alkM)
ASJ: AsACE_CH01534(alkB)
AGU: AS4_20720(alkM)
AUG: URS_2935
AVB: RYU24_14800(alkM)
ABOU: ACBO_17450(alkM)
SAGA: M5M_18065
MICC: AUP74_02288(alkB)
ASIP: AQUSIP_08790(alkB2)
LPN: lpg2997
LPH: LPV_3385
LPO: LPO_3336
LPM: LP6_3036
LPF: lpl2925
LPP: lpp3068
LPC: LPC_3312
LPA: lpa_04391
LPE: lp12_2989
LLO: LLO_2382
LHA: LHA_3251(alkB)
LCD: clem_00120(alkB2)
LLG: 44548918_02745(alkB1)
LJR: NCTC11533_02907(alkB1)
LCJ: NCTC11976_02676(alkB2)
LWA: SAMEA4504053_3509(alkB1)
LSS: NCTC12082_02020(alkB2)
MCA: MCA1639
MMAI: sS8_2252
CYQ: Q91_2194
HCH: HCH_04734(alkB)
ABO: ABO_0122(alkB2) ABO_2707(alkB1)
OAI: OLEAN_C23040(alkB2)
KGE: TQ33_1162
SALN: SALB1_1966
GPB: HDN1F_04190(alkM)
RPI: Rpic_4109
BMA: BMA0635(alkB)
BMV: BMASAVP1_A2377(alkB)
BML: BMA10229_A2910(alkB)
BMN: BMA10247_1692(alkB)
BMAL: DM55_2005
BMAE: DM78_1223
BMAQ: DM76_1980
BMAI: DM57_2646
BMAF: DM51_417
BMAZ: BM44_1494
BMAB: BM45_1057
BPS: BPSL2350
BPL: BURPS1106A_2735(alkB)
BPSE: BDL_3139
BPSM: BBQ_961
BPSU: BBN_1088
BPSD: BBX_1540
BPK: BBK_2606
BPSH: DR55_2170
BPSA: BBU_3210
BPSO: X996_1814
BUT: X994_86
BTE: BTH_I1814
BTQ: BTQ_2100
BTJ: BTJ_212
BTZ: BTL_1506
BTD: BTI_1284
BTV: BTHA_1610
BTHE: BTN_3269
BTHM: BTRA_1732
BTHA: DR62_39
BTHL: BG87_1719
BOK: DM82_1965
BOC: BG90_2747
BSAV: WS86_06745
BVE: AK36_2960
BCN: Bcen_0501
BCJ: BCAL3029
BCEN: DM39_808
BCEW: DM40_1635
BCEO: I35_0839
BAM: Bamb_0841
BMJ: BMULJ_00816(alkB)
BMU: Bmul_2418
BMK: DM80_719
BMUL: NP80_1069
BCT: GEM_2548
BCED: DM42_859
BDL: AK34_2200
BCON: NL30_10915
BUB: BW23_760
BLAT: WK25_04595
BTEI: WS51_15120
BSEM: WJ12_04495
BPSL: WS57_22415
BMEC: WJ16_04520
BSTG: WT74_04805
BGU: KS03_3293
BGO: BM43_306
BUK: MYA_0870
BUL: BW21_1432
BXE: Bxe_B1208
BXB: DR64_6524
BFN: OI25_6965
PDIO: PDMSB3_1898.1(alkB)
CABA: SBC2_71350
LIH: L63ED372_00180(alkB)
PBH: AAW51_0818(alkB1_2)
MPT: Mpe_B0606(alkB)
RVA: Rvan_1309
PSF: PSE_3490(alkB)
CAK: Caul_5439
RUT: FIU92_14690(alkB1)
DSH: Dshi_0027(alkB1)
PGD: Gal_03414
OAT: OAN307_c47130(alkB1)
OTM: OSB_09520(alkB2_1) OSB_30800(alkB2_2)
LAQU: R2C4_18865
SINL: DSM14862_00380(alkB2_1) DSM14862_01048(alkB2_2)
SPSE: SULPSESMR1_02992(alkB2) SULPSESMR1_04191(alkB1)
RID: RIdsm_00089(alkB2_1) RIdsm_02192(alkB2_2) RIdsm_03483(alkB2_3)
ROH: FIU89_01000(alkB1) FIU89_06770(alkB2)
MARU: FIU81_02135(alkB2) FIU81_15260(alkB3)
ROT: FIV09_01155(alkB1) FIV09_03085(alkB2)
RSP: RSP_1467
PDE: Pden_2098
PMAU: CP157_02858(alkB2)
PTP: RCA23_c00460(alkB)
LVS: LOKVESSMR4R_03748(alkB2)
PAMO: BAR1_14890
PALW: PSAL_002440(alkB2_1) PSAL_029980(alkB2_2)
GAK: X907_1562
SPHK: SKP52_24510(alkB)
SFLA: SPHFLASMR4Y_00404(alkB1)
RCE: RC1_0393(alkB)
MTU: Rv3252c(alkB)
MTC: MT3350(alkB)
MRA: MRA_3293(alkB)
MTUR: CFBS_3441(alkB)
MTO: MTCTRI2_3319(alkB)
MTD: UDA_3252c(alkB)
MTN: ERDMAN_3566(alkB)
MTUC: J113_22685
MTUE: J114_17435
MTUL: TBHG_03188
MTUT: HKBT1_3428(alkB)
MTUU: HKBT2_3435(alkB)
MTQ: HKBS1_3438(alkB)
MBO: BQ2027_MB3280C(alkB)
MBB: BCG_3281c(alkB)
MBT: JTY_3277(alkB)
MBM: BCGMEX_3279c(alkB)
MBX: BCGT_3119
MAF: MAF_32630(alkB)
MMIC: RN08_3588
MCE: MCAN_32711(alkB)
MCQ: BN44_70036(alkB)
MCV: BN43_60261(alkB)
MCX: BN42_41302(alkB)
MCZ: BN45_60281(alkB)
MPA: MAP_3364c
MAO: MAP4_0418
MAVI: RC58_01995
MAVU: RE97_02005
MAV: MAV_4215
MIT: OCO_40740
MIA: OCU_40650
MID: MIP_06136
MYO: OEM_41000
MIR: OCQ_42010
MLP: MLM_3375
MMAN: MMAN_28780(alkB)
MUL: MUL_2749(alkB_1)
MMC: Mmcs_1333
MKM: Mkms_1350
MJL: Mjls_1369
MMI: MMAR_1291(alkB) MMAR_3516(alkB_1)
MMAE: MMARE11_12570(alkB) MMARE11_34330(alkB_1)
MMM: W7S_20340
MLI: MULP_01451(alkB) MULP_03769(alkB_1)
MSHG: MSG_01190(alkB)
MFJ: MFLOJ_21980(alkB)
MSTO: MSTO_25690(alkB)
MSIM: MSIM_12980(alkB)
MSAK: MSAS_48430(alkB)
MNV: MNVI_28280(alkB)
MCOO: MCOO_44730(alkB)
MBAI: MB901379_01183(alkB_1) MB901379_03128(alkB_2)
MSEO: MSEO_51230(alkB)
MPSE: MPSD_14690(alkB) MPSD_35950
MSHO: MSHO_49370 MSHO_60180(alkB)
MLJ: MLAC_04600(alkB)
MSHJ: MSHI_24800(alkB)
MSG: MSMEI_1797(alkB)
MPHL: MPHLCCUG_01637(alkB)
MVQ: MYVA_1486 MYVA_2975(alkB)
MTHN: 4412656_00281(alkB) 4412656_01195(alkB1)
MHAS: MHAS_00512(alkB)
MAUU: NCTC10437_01449(alkB1_1) NCTC10437_02997(alkB1_2)
MMOR: MMOR_51110
MAIC: MAIC_13140(alkB)
MALV: MALV_19430
MARZ: MARA_24200
MHEV: MHEL_11000 MHEL_36340(alkB)
MSAR: MSAR_04140(alkB)
MANY: MANY_27790 MANY_52790(alkB)
MBOK: MBOE_55880
MFLV: NCTC10271_03853(alkB1)
MCEE: MCEL_20230
MAB: MAB_3598c
MABB: MASS_3605
MCHE: BB28_18405
MSTE: MSTE_03730
MSAL: DSM43276_03396(alkB)
MJD: JDM601_2991(alkB) JDM601_3998(alkB)
MTER: 4434518_02979(alkB_1) 4434518_03945(alkB_2)
MMIN: MMIN_14500
MHIB: MHIB_37760
CJK: jk1916(alkM)
CVA: CVAR_0139(alkB)
CTER: A606_11475
CGY: CGLY_01080(alkB)
CPRE: Csp1_01820(alkB1)
NFR: ERS450000_00739(alkB1_1) ERS450000_05310(alkB) ERS450000_05314(alkB1_2)
NCY: NOCYR_2725(alkB) NOCYR_2826(alkB) NOCYR_4338(alkB) NOCYR_4341(alkA)
NAD: NCTC11293_03692(alkB) NCTC11293_05918(alkB1_1) NCTC11293_05922(alkB1_2)
RHA: RHA1_ro02534(alkB)
RER: RER_07460(alkB) RER_21620(alkB) RER_24030(alkB) RER_54580(alkB)
ROP: ROP_22570(alkB) ROP_pROB01-04350(alkB)
REQ: REQ_33430(alkB)
RFA: A3L23_00039(alkB_1) A3L23_01166(alkB_2) A3L23_01600(alkB_3)
RHS: A3Q41_01756(alkB_1) A3Q41_02203(alkB_2) A3Q41_03374(alkB_3)
RHU: A3Q40_00237(alkB) A3Q40_02026(alkB1_1) A3Q40_02998(alkB1_2)
RRT: 4535765_03344(alkB_2) 4535765_04073(alkB1)
RCR: NCTC10994_03261(alkB1) NCTC10994_03913(alkB_2)
GBR: Gbro_4212
GOR: KTR9_2914
GOM: D7316_05156(alkB)
TPR: Tpau_2750
SRT: Srot_0768
SALS: SLNWT_0909
LMOI: VV02_18530
NCA: Noca_0122
NDK: I601_1337(alkB)
NAQU: ENKNEFLB_00076(alkB)
TCU: Tcur_0560
FAL: FRAAL1986
AMD: AMED_6400
AMN: RAM_32810
AMM: AMES_6308
AMZ: B737_6308
AOI: AORI_4274
AORI: SD37_21850
PSEA: WY02_07625
PSEE: FRP1_16935
PSEH: XF36_17955
PAUT: Pdca_22380
ALO: CRK58101
MIL: ML5_4476
ASE: ACPL_4910(alkB)
ACTS: ACWT_4780
CAI: Caci_1373
CWO: Cwoe_5739
FLM: MY04_0667
DDO: I597_0625(alkB2)
MLT: VC82_1335
NDO: DDD_1421
WIN: WPG_1326
KOS: KORDIASMS9_01136(alkB1)
KAN: IMCC3317_29330(alkB1)
 » show all
Reference
  Authors
Smits TH, Witholt B, van Beilen JB
  Title
Functional characterization of genes involved in alkane oxidation by Pseudomonas aeruginosa.
  Journal
Antonie Van Leeuwenhoek 84:193-200 (2003)
DOI:10.1023/A:1026000622765
  Sequence
Reference
  Authors
van Beilen JB, Marin MM, Smits TH, Rothlisberger M, Franchini AG, Witholt B, Rojo F
  Title
Characterization of two alkane hydroxylase genes from the marine hydrocarbonoclastic bacterium Alcanivorax borkumensis.
  Journal
Environ Microbiol 6:264-73 (2004)
DOI:10.1111/j.1462-2920.2004.00567.x
  Sequence
Reference
PMID:9546151
  Authors
Ratajczak A, Geissdorfer W, Hillen W
  Title
Alkane hydroxylase from Acinetobacter sp. strain ADP1 is encoded by alkM and belongs to a new family of bacterial integral-membrane hydrocarbon hydroxylases.
  Journal
Appl Environ Microbiol 64:1175-9 (1998)
DOI:10.1128/AEM.64.4.1175-1179.1998
  Sequence
[aci:ACIAD1411]

KEGG   ENZYME: 1.14.15.3
Entry
EC 1.14.15.3                Enzyme                                 
Name
alkane 1-monooxygenase;
alkane 1-hydroxylase;
omega-hydroxylase;
fatty acid omega-hydroxylase;
alkane monooxygenase;
1-hydroxylase;
alkane hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
alkane,reduced-rubredoxin:oxygen 1-oxidoreductase
Reaction(IUBMB)
octane + 2 reduced rubredoxin + O2 + 2 H+ = 1-octanol + 2 oxidized rubredoxin + H2O [RN:R02879]
Reaction(KEGG)
R02879;
(other) R01347 R02281 R06945
Substrate
octane [CPD:C01387];
reduced rubredoxin [CPD:C00340];
O2 [CPD:C00007];
H+ [CPD:C00080]
Product
1-octanol [CPD:C00756];
oxidized rubredoxin [CPD:C00435];
H2O [CPD:C00001]
Comment
Some enzymes in this group are heme-thiolate proteins (P-450). Also hydroxylates fatty acids in the omega-position.
History
EC 1.14.15.3 created 1972
Pathway
ec00071  Fatty acid degradation
ec00930  Caprolactam degradation
Orthology
K00496  alkane 1-monooxygenase
Genes
PSDDSC_08960
XBCELE36_04735
DTXATSB10_28120
VASGT360_06145
PAEPA1525(alkB2) PA2574(alkB1)
PAEVN297_1567(alkB2) N297_2651(alkB1)
PAEIN296_1567(alkB2) N296_2651(alkB1)
PAUPA14_30810(alkB1) PA14_44700(alkB2)
PAPPSPA7_2642 PSPA7_3808
PAGPLES_27201(alkB1) PLES_38031(alkB2)
PAFPAM18_2419(alkB1) PAM18_3523(alkB2)
PNCNCGM2_2412(alkB2) NCGM2_3586(alkB1)
PAEBNCGM1900_3944(alkB1) NCGM1900_5055(alkB2)
PDKPADK2_12360 PADK2_18100
PSGG655_12135 G655_17595
PRPM062_08150 M062_13675
PAEPPA1S_12750 PA1S_18400
PAERPA1R_gp0371 PA1R_gp5107
PAEMU769_12320 U769_18135
PAELT223_13960 T223_19460
PAESSCV20265_2681 SCV20265_3892
PAEUBN889_01620(alkB2) BN889_02835(alkB1)
PAEGAI22_15585 AI22_21160
PAECM802_1564(alkB2) M802_2648(alkB1)
PAEOM801_1566(alkB2) M801_2516(alkB1)
PMYPmen_0443 Pmen_2750
PMKMDS_1928
PALCA0T30_07635
PCQPcP3B5_23990(alkB2)
PMUIG4G71_19060
PFLPFL_2935(alkB)
PPRCPFLCHA0_c29810(alkB1)
PPROPPC_2966(alkB)
PFNHZ99_00960
PFSPFLU_3535
PFCPflA506_2496(alkB)
PPZH045_10220
PFBVO64_0643
PTVAA957_27445
PVRPverR02_17470
PAZOAYR47_24130
POIBOP93_10865
PRXHRH33_15340
PFWPF1751_v1c29650
PFFPFLUOLIPICF721365
PFXA7318_14550
PDRH681_15325
PSKU771_18830
PKCPKB_2028(alkB2)
PSOSPOS17_2902(alkB)
PANRA7J50_2574
PYMAK972_2349
PALLUYA_14605
POJPtoMrB4_19950(alkB2)
PKHJLK41_15800
PTYJWV26_00670
PCAMHNE05_12245
PSEPC4K39_2998
PVWHU752_017320
PTRTHU722_0016730
PSAMHU731_000870
PSHHHU773_011755
PASGKSS96_13465
PTWTUM18999_38450(alkB2)
PAGRE2H98_03590
HPEGEAO82_00355 EAO82_19385
HAESLO767_01265
MAQMaqu_0440 Maqu_0610 Maqu_2843
MHCMARHY2735(alkM) MARHY2847(alkB)
MADHP15_2574(alkB) HP15_2892(alkB)
MBSMRBBS_1602(alkB1)
MSXAU14_05070
MPQABA45_07610
MARIACP86_03200 ACP86_04660 ACP86_20385
MLQASQ50_05500 ASQ50_08885
MSQBKP64_00375
MARAD0851_06390
MARJMARI_02610(alkB) MARI_17900(alkB1)
PRWPsycPRwf_2053
PSYYDLE54_09785
ACBA1S_1641
ABMABSDF1860(alkM)
ABYABAYE2014(alkM)
ABCACICU_01666
ABNAB57_1863
ABBABBFA_01834(alkB)
ABXABK1_2124
ABZABZJ_01827
ABRABTJ_02041
ABDABTW07_1882
ABHM3Q_2018
ABADABD1_16260(alkM)
ABJBJAB07104_02087
ABABBJAB0715_01849
ABAJBJAB0868_01788
ABAZP795_9080
ABKLX00_08275
ABAUIX87_19025
ABAAIX88_10110
ABWBL01_08560
ABALABLAC_24720
ACCBDGL_001009(alkM)
ANORR32_09795
ALCOTEC02_10020
ACALBUM88_05740 BUM88_08900
ASEII8T81_10440 I8T81_13055
ACDAOLE_10550 AOLE_13390
ACIACIAD1411(alkM)
ATTAMQ28_00290
AJORZ95_09650
ACWA0J50_09295
ACVAMD27_08710
AHLAHTJS_07460 AHTJS_09615
AJNBVL33_08495 BVL33_09335
ASOLBEN76_06895
ASJAsACE_CH01534(alkB)
AIDCTZ23_07770
ADVDJ533_10245
ARJDOM24_10030
AWUBEN71_09545
ACUMC9E88_011205
AGUAS4_20720(alkM)
AUGURS_2935
ALWFOB21_02200
ADSFPL17_03275 FPL17_06025
ABERBSR55_09925
ATNFM020_08375 FM020_08800
ACHICDG60_08195
AWGGFH30_06870
ASHAG8E00_08470
ATGJ4G44_09260
AVBRYU24_14800(alkM)
ABOUACBO_17450(alkM)
MBAHHYN46_04630 HYN46_14535 HYN46_15245
SJASJ2017_3778
SEURFM038_020345
SINVK8B83_21295
LALAT746_01950
HMIsoil367_08400
SAGAM5M_18065
SNANI6N98_02170 I6N98_11835 I6N98_13845
ZALAZF00_02930 AZF00_08230 AZF00_15755
MICCAUP74_02288(alkB)
MAGAMag101_07105
ASIPAQUSIP_08790(alkB2)
LPNlpg2997
LPHLPV_3385
LPOLPO_3336
LPULPE509_00009
LPMLP6_3036
LPFlpl2925
LPPlpp3068
LPCLPC_3312
LPAlpa_04391
LPElp12_2989
LLOLLO_2382
LHALHA_3251(alkB)
LCDclem_00120(alkB2)
LSHCAB17_17210
LLG44548918_02745(alkB1)
LJRNCTC11533_02907(alkB1)
LCJNCTC11976_02676(alkB2)
LWASAMEA4504053_3509(alkB1)
LSSNCTC12082_02020(alkB2)
MCAMCA1639
METUGNH96_08815
MMAIsS8_2252
MEINmethR_P3180
MOZMoryE10_15200
MISZMishRS11D_17900
CYQQ91_2194
CZACYCME_0227
CYYCPC19_01830
WMAWM2015_2247
WOCBA177_08740
HCHHCH_04734(alkB)
HAHEENC22_09175
ABOABO_0122(alkB2) ABO_2707(alkB1)
ADIB5T_00103(alkB2) B5T_00721 B5T_04393
APACS7S_00120 S7S_00220 S7S_06720 S7S_11290
ALNAS19_01260 AS19_27640
AXEP40_00520 P40_03400 P40_21415
KAKKalk_12905
TOLTOL_1175 TOL_1423
TORR615_10390 R615_11545
OAIOLEAN_C23040(alkB2)
BSANCHH28_13540
BMARHF888_15570
VCWGJQ55_08745
OMEOLMES_3728
KGETQ33_1162
KSDKS2013_1211
SOKD0B54_11315 D0B54_15995 D0B54_22765
SINIGT972_05975 GT972_10155
FCEJN531_004395 JN531_006920
GBIPG2T_01500 PG2T_12610
SALNSALB1_1966
GPBHDN1F_04190(alkM)
RPIRpic_4109
RPFRpic12D_4221
RMNTK49_20990
RINACS15_3990
BMABMA0635(alkB)
BMVBMASAVP1_A2377(alkB)
BMLBMA10229_A2910(alkB)
BMNBMA10247_1692(alkB)
BMALDM55_2005
BMAEDM78_1223
BMAQDM76_1980
BMAIDM57_2646
BMAFDM51_417
BMAZBM44_1494
BMABBM45_1057
BPSBPSL2350
BPMBURPS1710b_2801
BPLBURPS1106A_2735(alkB)
BPDBURPS668_2678
BPRGBP346_A2857
BPSEBDL_3139
BPSMBBQ_961
BPSUBBN_1088
BPSDBBX_1540
BPZBP1026B_I0975
BPQBPC006_I2776
BPKBBK_2606
BPSHDR55_2170
BPSABBU_3210
BPSOX996_1814
BUTX994_86
BTEBTH_I1814
BTQBTQ_2100
BTJBTJ_212
BTZBTL_1506
BTDBTI_1284
BTVBTHA_1610
BTHEBTN_3269
BTHMBTRA_1732
BTHADR62_39
BTHLBG87_1719
BOKDM82_1965
BOCBG90_2747
BUUWS70_05970
BSAVWS86_06745
BVIBcep1808_0897
BVEAK36_2960
BURBcep18194_A4085
BCNBcen_0501
BCHBcen2424_0980
BCMBcenmc03_0941
BCJBCAL3029
BCENDM39_808
BCEWDM40_1635
BCEOI35_0839
BAMBamb_0841
BACBamMC406_0853
BMJBMULJ_00816(alkB)
BMUBmul_2418
BMKDM80_719
BMULNP80_1069
BCTGEM_2548
BCEDDM42_859
BCEPAPZ15_08575
BDLAK34_2200
BPYRABD05_10470
BCONNL30_10915
BUBBW23_760
BDFWI26_04360
BLATWK25_04595
BTEIWS51_15120
BSEMWJ12_04495
BPSLWS57_22415
BMECWJ16_04520
BSTGWT74_04805
BSTLBBJ41_07290
BANNJFN94_04685
BGLbglu_1g25240
BGUKS03_3293
BGDbgla_1g28520
BGOBM43_306
BUKMYA_0870
BULBW21_1432
BPLAbpln_1g26180
BUDAQ610_06520
BURKDM992_16755
BXEBxe_B1208
BXBDR64_6524
BPYBphyt_5401
BUZAYM40_27295
BFNOI25_6965
PARBCJU94_23135
PCAFDSC91_001277 DSC91_007611
PMEGFNZ07_18370
PDIOPDMSB3_1898.1(alkB)
PFGAB870_23570
CABASBC2_71350
LIMNHKT17_10220
RSBRS694_18200
RHGEXZ61_20755
ACKC380_12125
LIHL63ED372_00180(alkB)
SIMPC6571_11545
PBHAAW51_0818(alkB1_2)
MPTMpe_B0606(alkB)
UPVEJN92_08105
NOKFAY22_15630
PKTAT984_12690
IDCLRM40_09015
NIVJY500_01625
FMYHO273_12195
MRMA7982_08709
BBAEFRD01_05945
HOEIMCC20628_02571
ABAWD5400_08655
BRKCWS35_21070
BELBE61_47980
BSEPHAP48_0043395
BQBJ4P68_0002745
RVARvan_1309
PSFPSE_3490(alkB)
CAKCaul_5439
SILSPO1341 SPO3449
SITTM1040_2646
RUAD1823_16765
RUTFIU92_14690(alkB1)
JANJann_0394 Jann_1213
RPONG3256_01145 G3256_13110
DSHDshi_0027(alkB1)
PGAPGA1_c33550
PGLPGA2_c31810
PGDGal_03414
PHPPhaeoP97_03265
PPICPhaeoP14_03153
PHQD1820_11560
OATOAN307_c47130(alkB1)
OAROA238_c27230
OTMOSB_09520(alkB2_1) OSB_30800(alkB2_2)
OCTFTO60_10890 FTO60_15425
LMDMETH_19350
LEJETW24_18875
LAQUR2C4_18865
REDroselon_00148 roselon_00871
CIDP73_0364 P73_0386 P73_3494
CMARIMCC12053_1887 IMCC12053_2486
CEHCEW89_07850 CEW89_12015
MALGMALG_00119 MALG_01035
CONTQ29_11915 TQ29_17065
YPACCEW88_14690
YANAYJ57_17040
TPROGa0080559_TMP1054 Ga0080559_TMP555
PABYGa0080574_TMP1436 Ga0080574_TMP4685
SUAMBOO69_05895 BOO69_16800
SULZC1J03_01805
SULIC1J05_19485
SULDB5M07_01890 B5M07_11590
SPOTG6548_00990 G6548_11830
SMEDJNX03_06915 JNX03_14660
SINLDSM14862_00380(alkB2_1) DSM14862_01048(alkB2_2)
SPSESULPSESMR1_02992(alkB2) SULPSESMR1_04191(alkB1)
TOMBWR18_04840 BWR18_15845
RMMROSMUCSMR3_02985(alkB2) ROSMUCSMR3_03670(alkB2)
ROKRAK1035_1884 RAK1035_2496
RIDRIdsm_00089(alkB2_1) RIdsm_02192(alkB2_2) RIdsm_03483(alkB2_3)
ROMEI983_05130 EI983_16920
ROHFIU89_01000(alkB1) FIU89_06770(alkB2)
AHTANTHELSMS3_00166(alkB2) ANTHELSMS3_04081(alkB1)
SAGUCDO87_01990 CDO87_06690
THAACFI11_16135 CFI11_21755
OCDFHY55_02085 FHY55_14840
MARUFIU81_02135(alkB2) FIU81_15260(alkB3)
ROTFIV09_01155(alkB1) FIV09_03085(alkB2)
MALUKU6B_07760 KU6B_17700
TGLHFZ77_05560 HFZ77_12270 HFZ77_12810
HATRC74_05540
PALXGQA70_03535 GQA70_13345
RSPRSP_1467
RSHRsph17029_0118
RSQRsph17025_0065
RSKRSKD131_2858
CAZTLV780_00325
RCPRCAP_rcc02390
RHPLPB142_01740 LPB142_11240
RBLB6K69_09540 B6K69_15410
PDEPden_2098
PAMIJCM7686_3074
PYEA6J80_07425
PCONB0A89_06825
PZHCX676_17375
PAROCUV01_09725 CUV01_12210
PARUCYR75_07325 CYR75_09995
PAMNJCM7685_2099 JCM7685_2586
PARSDRW48_01275
PARREOJ32_03645
PKDF8A10_08435
PPANESD82_17470
PLIAE4191_01610
PSANHGN31_02690 HGN31_10490
PMAUCP157_02858(alkB2)
PTPRCA23_c00460(alkB)
RMBK529_012810
DAAAKL17_2723 AKL17_4362 AKL17_4608
DONBSK21_09875 BSK21_13355
THWBMG03_01325 BMG03_07035
TECAKL02_000585 AKL02_005925
LVSLOKVESSMR4R_03748(alkB2)
RBGBG454_08540 BG454_14335
GEHHYN69_00150 HYN69_04430
GFUKM031_11365 KM031_15685
TAWEI545_02625 EI545_11960
SALOEF888_00785
SEDIEBB79_19660
PSEBEOK75_07930 EOK75_18115
PAEDG5B38_12060 G5B38_12960
MONG8E03_02020 G8E03_03700
PAMOBAR1_14890
PSHQF3W81_09710 F3W81_13660
POZI0K15_09445
PALWPSAL_002440(alkB2_1) PSAL_029980(alkB2_2)
PPAFI8N54_00325 I8N54_03765
CACTHZ995_02670 HZ995_07195
RBZB9057_03540 B9057_13090
THASC6Y53_06580
CMAGCBW24_01090 CBW24_05165
FAPGR316_07745
GCEKYE46_00795 KYE46_14655
NSMJO391_08015 JO391_19035
GAKX907_1562
HYTHXX25_11785
SPHKSKP52_24510(alkB)
SECHB18_19400 B18_24960
SBARH5V43_03530
SFLASPHFLASMR4Y_00404(alkB1)
SPHYCHN51_00370
PALGHFP57_08315
RCERC1_0393(alkB)
PBRPB2503_09204
MTURv3252c(alkB)
MTVRVBD_3252c
MTCMT3350(alkB)
MRAMRA_3293(alkB)
MTFTBFG_13281
MTBTBMG_03300
MTKTBSG_03323
MTZTBXG_003280
MTGMRGA327_20020
MTECCDC5079_3000
MTURCFBS_3441(alkB)
MTLCCDC5180_2963
MTOMTCTRI2_3319(alkB)
MTDUDA_3252c(alkB)
MTNERDMAN_3566(alkB)
MTJJ112_17475
MTUBMT7199_3294
MTUCJ113_22685
MTUEJ114_17435
MTXM943_16800
MTULTBHG_03188
MTUTHKBT1_3428(alkB)
MTUUHKBT2_3435(alkB)
MTQHKBS1_3438(alkB)
MBOBQ2027_MB3280C(alkB)
MBBBCG_3281c(alkB)
MBTJTY_3277(alkB)
MBMBCGMEX_3279c(alkB)
MBKK60_033810
MBXBCGT_3119
MAFMAF_32630(alkB)
MMICRN08_3588
MCEMCAN_32711(alkB)
MCQBN44_70036(alkB)
MCVBN43_60261(alkB)
MCXBN42_41302(alkB)
MCZBN45_60281(alkB)
MPAMAP_3364c
MAOMAP4_0418
MAVIRC58_01995
MAVURE97_02005
MAVMAV_4215
MITOCO_40740
MIAOCU_40650
MIDMIP_06136
MYOOEM_41000
MCHIAN480_21395
MIROCQ_42010
MMALCKJ54_19425
MLPMLM_3375
MMANMMAN_28780(alkB)
MSAMycsm_01384
MULMUL_2749(alkB_1)
MMCMmcs_1333
MKMMkms_1350
MJLMjls_1369
MMIMMAR_1291(alkB) MMAR_3516(alkB_1)
MMAEMMARE11_12570(alkB) MMARE11_34330(alkB_1)
MMMW7S_20340
MLIMULP_01451(alkB) MULP_03769(alkB_1)
MKNMKAN_04295 MKAN_21250
MYVG155_09390
MYEAB431_07910
MGOAFA91_29715
MHADB586_17445 B586_19815
MDXBTO20_03125
MSHGMSG_01190(alkB)
MFJMFLOJ_21980(alkB)
MSTOMSTO_25690(alkB)
MSIMMSIM_12980(alkB)
MSAKMSAS_48430(alkB)
MKUI2456_06520
MGROFZ046_13240
MXEMYXE_36990
MNVMNVI_28280(alkB)
MPAGC0J29_07185 C0J29_12555 C0J29_20205
MNMMNVM_22020 MNVM_30780(alkB)
MGORH0P51_06405 H0P51_11995
MCOOMCOO_44730(alkB)
MBAIMB901379_01183(alkB_1) MB901379_03128(alkB_2)
MSEOMSEO_51230(alkB)
MPSEMPSD_14690(alkB) MPSD_35950
MSHOMSHO_49370 MSHO_60180(alkB)
MHEKJMUB5695_03645
MGAUMGALJ_04980 MGALJ_57870
MLJMLAC_04600(alkB)
MBRDMBRA_03090 MBRA_03510 MBRA_26240
MSHJMSHI_24800(alkB)
MKRMKOR_20120(alkB) MKOR_35350
MDFK0O62_08000 K0O62_27585
MMAMK3U93_05820
MHOLK3U96_19335
MHERK3U94_16975 K3U94_21885
MSENK3U95_04740 K3U95_12860 K3U95_20385
MPAEK0O64_07475
MSPGF6B93_05535 F6B93_14335
MOTLTS72_06885 LTS72_18915
MVMMJO54_16980 MJO54_21825
MRFMJO55_07520 MJO55_14085
MPAAMKK62_18570 MKK62_18575
MSMMSMEG_1839
MSGMSMEI_1797(alkB)
MSBLJ00_09170
MSNLI99_09170
MSHLI98_09170
MVAMvan_1742 Mvan_3100
MGIMflv_3369 Mflv_4721
MSPMspyr1_27000 Mspyr1_40540
MCBMycch_1351 Mycch_2783
MNED174_00375 D174_08465
MYNMyAD_00360 MyAD_08315
MFTXA26_18780
MPHLMPHLCCUG_01637(alkB)
MVQMYVA_1486 MYVA_2975(alkB)
MLLB1R94_21250
MRHMycrhN_0412
MTHN4412656_00281(alkB) 4412656_01195(alkB1)
MHASMHAS_00512(alkB)
MDUMDUV_12850 MDUV_27970
MCHTMCHIJ_50110
MAUUNCTC10437_01449(alkB1_1) NCTC10437_02997(alkB1_2)
MMAGMMAD_13870 MMAD_14930
MMORMMOR_51110
MFXMFAL_19080
MAICMAIC_13140(alkB)
MIJMINS_16060
MALVMALV_19430
MTYMTOK_35230
MPSCMPSYJ_36280 MPSYJ_49580
MARZMARA_24200
MGADMGAD_19080 MGAD_25130
MHEVMHEL_11000 MHEL_36340(alkB)
MSARMSAR_04140(alkB)
MANYMANY_27790 MANY_52790(alkB)
MAUBMAUB_16970(alkB) MAUB_48740 MAUB_48860
MPOFMPOR_20280 MPOR_33650
MPHUMPHO_20760 MPHO_20910 MPHO_54320(alkB)
MMUCC1S78_007880 C1S78_007945 C1S78_020420
MMATMMAGJ_38250 MMAGJ_47680
MBOKMBOE_55880
MFGK6L26_23140
MSEIMSEDJ_27460
MFLVNCTC10271_03853(alkB1)
MCEEMCEL_20230
MABMAB_3598c
MMVMYCMA_1974
MABBMASS_3605
MABLMMASJCM_3595
MCHEBB28_18405
MIZBAB75_20470
MSTEMSTE_03730
MSAOMYCSP_16550
MSALDSM43276_03396(alkB)
MJDJDM601_2991(alkB) JDM601_3998(alkB)
MTER4434518_02979(alkB_1) 4434518_03945(alkB_2)
MMINMMIN_14500
MHIBMHIB_37760
ASDAS9A_2113 AS9A_2121 AS9A_3799
MPAKMIU77_01980 MIU77_13930
CJKjk1916(alkM)
CVACVAR_0139(alkB)
CTERA606_11475
CFNCFAL_02965
CGYCGLY_01080(alkB)
CXEFOB82_09135
CPRECsp1_01820(alkB1)
CZOIAU67_08940
NFANFA_33210 NFA_46140 NFA_46180
NFRERS450000_00739(alkB1_1) ERS450000_05310(alkB) ERS450000_05314(alkB1_2)
NCYNOCYR_2725(alkB) NOCYR_2826(alkB) NOCYR_4338(alkB) NOCYR_4341(alkA)
NBRO3I_035125 O3I_035145
NNONONO_c08910 NONO_c46180(alkB) NONO_c63170 NONO_c63220
NSLBOX37_15220 BOX37_24610 BOX37_24625
NSRNS506_02079 NS506_05426
NTPCRH09_32590
NOZDMB37_06055 DMB37_13785 DMB37_13805
NODFOH10_03640 FOH10_11250
NAHF5544_37040 F5544_37060 F5544_39215
NADNCTC11293_03692(alkB) NCTC11293_05918(alkB1_1) NCTC11293_05922(alkB1_2)
NWLNWFMUON74_13520
NIEKV110_17620 KV110_26400 KV110_34160 KV110_34180
NTCKHQ06_12850 KHQ06_20790 KHQ06_33785
NHUH0264_12310 H0264_36700
NYALTV02_14665 LTV02_20635
NGPLTT66_00645 LTT66_19785 LTT66_19805
RHARHA1_ro02534(alkB)
RERRER_07460(alkB) RER_21620(alkB) RER_24030(alkB) RER_54580(alkB)
REYO5Y_03630 O5Y_10330 O5Y_11270 O5Y_25995
REBXU06_03870 XU06_10555 XU06_11480 XU06_26275
RQIC1M55_04110 C1M55_06260 C1M55_10995 C1M55_12535 C1M55_27520
ROPROP_22570(alkB) ROP_pROB01-04350(alkB)
ROAPd630_LPD06759
REQREQ_33430(alkB)
RPYY013_07620 Y013_10875 Y013_14995
RBYCEJ39_18540 CEJ39_21660
RHBNY08_1675 NY08_2959 NY08_3436
RAVAAT18_22445
RFAA3L23_00039(alkB_1) A3L23_01166(alkB_2) A3L23_01600(alkB_3)
RHSA3Q41_01756(alkB_1) A3Q41_02203(alkB_2) A3Q41_03374(alkB_3)
RHWBFN03_04505
RRZCS378_10250 CS378_12255
RHUA3Q40_00237(alkB) A3Q40_02026(alkB1_1) A3Q40_02998(alkB1_2)
RHQIM25_02605 IM25_21935
RHODAOT96_07485 AOT96_14505 AOT96_16650 AOT96_21175 AOT96_22745
RRT4535765_03344(alkB_2) 4535765_04073(alkB1)
RCRNCTC10994_03261(alkB1) NCTC10994_03913(alkB_2)
RTMG4H71_21630
RKOJWS14_13290
RGOKYT97_04920 KYT97_07750 KYT97_25200
GBRGbro_4212
GORKTR9_2914
GOQACH46_19590
GTABCM27_14965
GOCCXX93_04035 CXX93_06965
GITC6V83_00720
GOMD7316_05156(alkB)
GAMGII34_06700 GII34_20580
GPDGII33_02215 GII33_06150
GJIH1R19_14075
GHNMVF96_14475
SPINKV203_09945 KV203_15530
TPRTpau_2750
TSMASU32_15355
SRTSrot_0768
DTMBJL86_0023
DITC3V38_06555
DIZCT688_00095 CT688_01540
DPCA6048_00100 A6048_01605
DLUA6035_00150
SALSSLNWT_0909
SCIB446_00650 B446_34640
SVTSVTN_29895
SNZDC008_34655
SRKFGW37_00480
SCHFIPT68_00765
SXNIAG42_01595
LMOIVV02_18530
JLIEXU32_09700
NCANoca_0122
NDKI601_1337(alkB)
NOYEXE57_11480
NOIFCL41_15700
NOOFE634_00215
NSNEXE58_07580
NBEBack2_03940
NANOG5V58_23145
NMESH9L09_09320
NAROCFH99_01025 CFH99_01465
NPIG7071_04980
NAQUENKNEFLB_00076(alkB)
NROK8W59_00255
NCQK6T13_00310
NPCKUV85_12770
PSIMKR76_00635 KR76_01185
AERAERYTH_04685
AEZC3E78_03660
AEBC6I20_12235
AEFGEV26_14005
TCUTcur_0560
FRAFrancci3_1251
FREFranean1_2192
FRIFraEuI1c_2181
FALFRAAL1986
AMDAMED_6400
AMNRAM_32810
AMMAMES_6308
AMZB737_6308
AOIAORI_4274
AJAAJAP_12590 AJAP_17505
AMYCCU254_33490 CU254_34530
AMYBBKN51_14450
AORISD37_21850
PSEAWY02_07625
PSEEFRP1_16935
PSEHXF36_17955
PSEQAD006_24385
PECQAD017_03975
PAUTPdca_22380
LEDBBK82_00460
ALOCRK58101
MAUMicau_3940
MILML5_4476
MTEMGCE86_02670
MCABHXZ27_09700
MSAGGCM10017556_42190
ASEACPL_4910(alkB)
AMSAMIS_28610
ACTSACWT_4780
AIHAiant_79910
PSUUPsuf_059770 Psuf_091630
CATICS0771_67620
DVCDvina_17675 Dvina_23605
CCAZCOUCH_25840
CAICaci_1373
CWOCwoe_5739
SLRL21SP2_3309
LAJA0128_05975 A0128_13880
LKMEFP84_16680
LKBLPTSP3_g12260
TPXTurpa_1759
SCORJ3U87_21825
FLASY85_18695
FLSGLV81_02985
FLPLK994_03225
FLVKJS94_11330
HHYHalhy_3303
BBDBelba_3611
ALMAO498_08080
MDAIPZ59_10905
SMONAWR27_19795
RSIRunsl_1388
RUNDR864_15815
EOLEmtol_2027
HRSHER32_14815 HER32_14990
MTTFtrac_0880
FPFDCC35_03110
FLMMY04_0667
FYAKMW28_12820
FUVJR347_16635
FBCFB2170_05910
DOKMED134_09286
DDOI597_0625(alkB2)
MLTVC82_1335
SPONHME9304_01516
NDODDD_1421
NOMAAT17_07540
NSDBST91_11255
NOJEJ995_02415
POMMED152_06505
PHALH9I45_13840
WINWPG_1326
WIJBWZ20_09145
TJETJEJU_0991
TMPF9Y86_05550
LULLPB138_13865
FORFORMB_10180
FOHFORMA_10320
KOSKORDIASMS9_01136(alkB1)
KANIMCC3317_29330(alkB1)
AQBD1818_14565
AQAD1815_16695
AQDD1816_16420
MUREQY75_13050
MGELG5B37_10070
GAAHX109_05930
ASAGFGM00_17840
FLGLV716_07615
SABUMBM09_01810
OHOOweho_0550
CHYDH4K34_17330
 » show all
Reference
1  [PMID:4317878]
  Authors
Cardini G, Jurtshuk P.
  Title
The enzymatic hydroxylation of n-octane by Corynebacterium sp. strain 7E1C.
  Journal
J Biol Chem 245:2789-96 (1970)
Reference
2  [PMID:4395379]
  Authors
McKenna EJ, Coon MJ.
  Title
Enzymatic omega-oxidation. IV. Purification and properties of the omega-hydroxylase of Pseudomonas oleovorans.
  Journal
J Biol Chem 245:3882-9 (1970)
Reference
3  [PMID:4294330]
  Authors
Peterson JA, Kusunose M, Kusunose E, Coon MJ.
  Title
Enzymatic omega-oxidation. II. Function of rubredoxin as the electron carrier in omega-hydroxylation.
  Journal
J Biol Chem 242:4334-40 (1967)
Other DBs
ExplorEnz - The Enzyme Database: 1.14.15.3
IUBMB Enzyme Nomenclature: 1.14.15.3
ExPASy - ENZYME nomenclature database: 1.14.15.3
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.15.3
BRENDA, the Enzyme Database: 1.14.15.3
CAS: 9059-16-9

KEGG   REACTION: R06945
Entry
R06945                      Reaction                               
Definition
Cyclohexane + Oxygen + NADH + H+ <=> Cyclohexanol + NAD+ + H2O
Equation
Comment
Alkane monooxygenase (K00496) requires rubredoxin and rubredoxin reductase.
Reaction class
RC00001  C00003_C00004
RC00478  C00854_C11249
Enzyme
1.14.13.-       1.14.15.3
Pathway
rn00930  Caprolactam degradation
rn01120  Microbial metabolism in diverse environments
Orthology
K00496  alkane 1-monooxygenase [EC:1.14.15.3]

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