K00787                      KO                                     

farnesyl diphosphate synthase [EC:]
map00900  Terpenoid backbone biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map05164  Influenza A
map05166  Human T-cell leukemia virus 1 infection
M00366  C10-C20 isoprenoid biosynthesis, plants
M00367  C10-C20 isoprenoid biosynthesis, non-plant eukaryotes
H01933  Porokeratosis
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K00787  FDPS; farnesyl diphosphate synthase
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K00787  FDPS; farnesyl diphosphate synthase
   05164 Influenza A
    K00787  FDPS; farnesyl diphosphate synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K00787  FDPS; farnesyl diphosphate synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)  dimethylallyltranstransferase
     K00787  FDPS; farnesyl diphosphate synthase  (2E,6E)-farnesyl diphosphate synthase
     K00787  FDPS; farnesyl diphosphate synthase
Prenyltransferases [BR:ko01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   K00787  FDPS; farnesyl diphosphate synthase
Other DBs
RN: R01658 R02003
GO: 0004161 0004337
HSA: 2224(FDPS)
PTR: 457366(FDPS)
PPS: 100981763(FDPS) 100990091
GGO: 101130805(FDPS)
PON: 100172538(FDPS)
NLE: 100590882 100598529(FDPS)
MCC: 709287 717761(FDPS)
MCF: 101865059(FDPS) 102119088
CSAB: 103223880(FDPS) 103231848
CATY: 105590546 105593537(FDPS)
PANU: 101002939 101017660(FDPS)
RRO: 104659589(FDPS)
RBB: 108526849(FDPS)
TFN: 117074566(FDPS)
PTEH: 111543763(FDPS)
CJC: 100392642(FDPS)
SBQ: 101046369(FDPS)
MMUR: 105873165(FDPS)
MMU: 110196(Fdps)
MCAL: 110291229(Fdps)
MPAH: 110319996(Fdps)
RNO: 83791(Fdps)
MCOC: 116093150(Fdps)
MUN: 110548993(Fdps)
CGE: 100754883(Fdps)
PLEU: 114707887(Fdps)
NGI: 103750841(Fdps)
HGL: 101721614(Fdps)
CCAN: 109688018(Fdps)
OCU: 103350044(FDPS)
TUP: 102470600(FDPS)
CFA: 480129(FDPS)
VVP: 112918924(FDPS)
VLG: 121473744(FDPS)
AML: 100474496(FDPS)
UMR: 103668371(FDPS)
UAH: 113245269(FDPS)
ORO: 101363916(FDPS)
ELK: 111139000
MPUF: 101693108(FDPS)
EJU: 114198665(FDPS)
MLX: 118013886(FDPS) 118022280
FCA: 101086533(FDPS)
PTG: 102969585(FDPS)
PPAD: 109256231(FDPS)
AJU: 106981517(FDPS)
HHV: 120244668(FDPS)
BTA: 281156(FDPS)
BOM: 102273722(FDPS)
BIU: 109553630(FDPS)
BBUB: 102391217(FDPS)
CHX: 102186540(FDPS)
OAS: 101119093(FDPS)
ODA: 120855740(FDPS)
SSC: 100153932(FDPS)
CFR: 102522669(FDPS)
CBAI: 105068152(FDPS)
CDK: 105088801(FDPS)
BACU: 103016390(FDPS)
LVE: 103088735(FDPS)
OOR: 101289697(FDPS) 105748102
DLE: 111167172(FDPS)
PCAD: 102980744(FDPS)
ECB: 100063641(FDPS)
EPZ: 103552839(FDPS)
EAI: 106828488(FDPS)
MYB: 102240123 102255084(FDPS)
MYD: 102760204(FDPS)
MMYO: 118673211(FDPS)
MNA: 107543782(FDPS)
HAI: 109393390(FDPS)
DRO: 112316896(FDPS)
SHON: 118980557 118990153(FDPS)
AJM: 119039719(FDPS)
MMF: 118626915 118637250(FDPS)
PALE: 102888371(FDPS)
PGIG: 120592220(FDPS)
RAY: 107521462(FDPS)
MJV: 108407273(FDPS)
TOD: 119235441(FDPS)
LAV: 100667894(FDPS)
TMU: 101349919
MDO: 100021214
SHR: 100931055(FDPS)
PCW: 110211949(FDPS)
OAA: 114808132(FDPS)
GGA: 425061(FDPS)
PCOC: 116240869(FDPS)
MGP: 104914328(FDPS)
CJO: 107324526(FDPS)
NMEL: 110387952(FDPS)
ACYG: 106048516(FDPS)
TGU: 100226712(FDPS)
LSR: 110471484(FDPS)
SCAN: 103823952(FDPS)
PMOA: 120498950(FDPS)
GFR: 102042593(FDPS)
FAB: 101820504(FDPS)
PHI: 102110858(FDPS)
PMAJ: 107214522(FDPS)
CCAE: 111939533(FDPS)
ETL: 114069575(FDPS)
FPG: 101918908(FDPS)
FCH: 102060121(FDPS)
CLV: 102090748(FDPS)
EGZ: 104134867(FDPS)
NNI: 104020488(FDPS)
PADL: 103913293(FDPS)
AAM: 106494333(FDPS)
ASN: 102387537(FDPS)
AMJ: 102564885(FDPS)
CPOO: 109324808(FDPS)
GGN: 109305127(FDPS)
PSS: 102447860(FDPS)
CMY: 102943224(FDPS)
CPIC: 101941324(FDPS)
CABI: 116817237(FDPS)
ACS: 100565264(fdps)
PVT: 110080990(FDPS)
PBI: 103060467(FDPS)
PMUR: 107297026(FDPS)
PMUA: 114586416(FDPS)
ZVI: 118076121(FDPS)
GJA: 107119557(FDPS)
XLA: 414582(fdps.S) 735190(fdps.L)
XTR: 548584(fdps)
NPR: 108794229(FDPS)
DRE: 552997(fdps)
SRX: 107707162(fdps)
CCAR: 109075297
CAUA: 113059916 113116334(fdps)
IPU: 108267020(fdps)
PHYP: 113542221(fdps)
AMEX: 103044986(fdps)
EEE: 113570600(fdps)
TRU: 101065291(fdps)
LCO: 104934661(fdps)
NCC: 104958849(fdps)
CGOB: 115021548(fdps)
ELY: 117266311(fdps)
PLEP: 121945789(fdps)
SLUC: 116049569(fdps)
ECRA: 117946731(fdps)
PFLV: 114557155(fdps)
GAT: 120810328(fdps)
MSAM: 119897570(fdps)
CUD: 121513023(fdps)
MZE: 101473168(fdps)
ONL: 100706299(fdps)
OAU: 116315731(fdps)
OLA: 101157393(fdps)
OML: 112144006(fdps)
XMA: 102229268(fdps)
XCO: 114142353(fdps)
XHE: 116717840(fdps)
PRET: 103478183(fdps)
CVG: 107088393(fdps)
CTUL: 119782958(fdps)
NFU: 107379594(fdps)
KMR: 108241053(fdps)
ALIM: 106531569(fdps)
AOCE: 111571978
CSEM: 103388252(fdps)
POV: 109632968(fdps)
LCF: 108885928(fdps)
SDU: 111230131(fdps)
SLAL: 111652160(fdps)
XGL: 120784751(fdps)
HCQ: 109521052(fdps)
BPEC: 110163068(fdps)
MALB: 109964077(fdps)
SASA: 100195349(fpps) 106605924
OTW: 112235527(fdps) 112242342
OMY: 110520852 110520853(fdps)
SALP: 112075534(fdps)
ELS: 105024442(fdps)
SFM: 108924952(fdps)
PKI: 111840865(fdps)
AANG: 118236550(fdps)
LOC: 102696883(fdps)
PSPA: 121306997(fdps)
LCM: 102363777(FDPS)
BFO: 118409624
BBEL: 109482420
CIN: 100176910
SCLV: 120329548
SPU: 576515
APLC: 110982376
SKO: 102802847
DME: Dmel_CG12389(Fpps)
DER: 6547174
DSE: 6608640
DSI: Dsimw501_GD25915(Dsim_GD25915)
DAN: 6495260
DSR: 110179328
DPE: 6592826
DMN: 108159714
DWI: 6643284
DGR: 6559968
DAZ: 108617257
DNV: 108654916
DHE: 111604439
DVI: 6636477
LCQ: 111675931
ACOZ: 120952200
AARA: 120902392
AAG: 5578269
BIM: 100749317
BBIF: 117213223
BTER: 100650005
CCAL: 108624334
MGEN: 117226867
NMEA: 116425746
CGIG: 122402911
HST: 105183507
CFO: 105258274
FEX: 115233309
LHU: 105678756
PGC: 109859126
OBO: 105285204
PCF: 106788042
NVI: 100120871
CSOL: 105365356
MDL: 103577762
CCIN: 107265608
TCA: 661272(Fpps)
DPA: 109543592
ATD: 109608031
NVL: 108556289
APLN: 108743602
BMOR: 100101207(Fpps2) 100101208(Fpps3) 692433(Fps)
API: 100144905(Ipps) 100166187
DNX: 107163395
AGS: 114120037
CLEC: 106663309
ZNE: 110841246
DMK: 116936610
PVM: 113823975
HAME: 121872984
HAZT: 108666830
RSAN: 119405656
RMP: 119181434
TUT: 107360761
PTEP: 107450203
SDM: 118191753
CEL: CELE_R06C1.2(fdps-1)
CBR: CBG18688
BMY: BM_BM5248(Bma-fdps-1)
PCAN: 112559809
CRG: 105346203
MYI: 110451367
PMAX: 117336513
OBI: 106877226
LAK: 106175927
EGL: EGR_05723
NVE: 5512735
EPA: 110249558
ATEN: 116303569
ADF: 107344174
AMIL: 114949866
PDAM: 113666464
SPIS: 111345083
HMG: 100204892
AQU: 100635733
ATH: AT4G17190(FPS2) AT5G47770(FPS1)
THJ: 104812789
CPAP: 110817926
CIT: 102615408
PVY: 116122337
EGR: 104445569
VRA: 106775037
VAR: 108341763
VUN: 114186764
CCAJ: 109803502
APRC: 113869470
CAM: 101497550
LJA: Lj6g3v1708410.1(Lj6g3v1708410.1) Lj6g3v1708410.2(Lj6g3v1708410.2)
ADU: 107483040
AIP: 107638741
MNT: 21403112
POP: 7458466
PEU: 105111935
PALZ: 118032194
VVI: 100232975
VRI: 117908064
DCR: 108219876
NCOL: 116259007
DOSA: Os01t0695300-01(Os01g0695300) Os01t0703400-01(Os01g0703400) Os04t0657100-01(Os04g0657100) Os05t0543400-01(Os05g0543400)
DCT: 110096432
PEQ: 110034180
ATR: 18447570
PPP: 112276317
ERC: Ecym_8102
KMX: KLMA_10389(FPS1)
NCS: NCAS_0B08330(NCAS0B08330)
NDI: NDAI_0A00910(NDAI0A00910)
TPF: TPHA_0E03340(TPHA0E03340)
TBL: TBLA_0C05770(TBLA0C05770)
TDL: TDEL_0C03780(TDEL0C03780)
KAF: KAFR_0G00430(KAFR0G00430)
PIC: PICST_89338(ERG20)
SLB: AWJ20_2504(ERG20)
BNN: FOA43_000036(FPS1)
BBRX: BRETT_001080(FPS1)
NCR: NCU01175(fpp)
MGR: MGG_08649
SSCK: SPSK_06442
CMT: CCM_03203
MBE: MBM_06938
ANI: AN8012.2
ANG: ANI_1_1456024(An02g10350) ANI_1_1504144(An16g01670)
ABE: ARB_06803
TVE: TRV_06757
PTE: PTT_11298
SPO: SPAC6F12.13c(fps1) SPBC36.06c(spo9)
CNE: CNE04510
TASA: A1Q1_07053
MGL: MGL_0638
MRT: MRET_2506
DFA: DFA_02231(pakF)
PCB: PCHAS_092460(PC000417.01.0)
TAN: TA17400
TPV: TP03_0857
BBO: BBOV_I000120(16.m00760)
CPV: cgd4_2550
SMIN: v1.2.018339.t1(symbB.v1.2.018339.t1) v1.2.038912.t1(symbB.v1.2.038912.t1)
SPAR: SPRG_10991
LMA: LMJF_22_1360(FPPS)
LIF: LINJ_22_1210(FPPS)
LBZ: LBRM_22_1240(FPPS)
 » show all
Vandermoten S, Haubruge E, Cusson M
New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition.
Cell Mol Life Sci 66:3685-95 (2009)
Cunillera N, Arro M, Delourme D, Karst F, Boronat A, Ferrer A
Arabidopsis thaliana contains two differentially expressed farnesyl-diphosphate synthase genes.
J Biol Chem 271:7774-80 (1996)
Wilkin DJ, Kutsunai SY, Edwards PA
Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester.
J Biol Chem 265:4607-14 (1990)

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