KEGG   ORTHOLOGY: K01242
Entry
K01242                      KO                                     

Symbol
CD38
Name
ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map04020  Calcium signaling pathway
map04640  Hematopoietic cell lineage
map04921  Oxytocin signaling pathway
map04970  Salivary secretion
map04972  Pancreatic secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K01242  CD38; ADP-ribosyl cyclase 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K01242  CD38; ADP-ribosyl cyclase 1
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K01242  CD38; ADP-ribosyl cyclase 1
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K01242  CD38; ADP-ribosyl cyclase 1
  09154 Digestive system
   04970 Salivary secretion
    K01242  CD38; ADP-ribosyl cyclase 1
   04972 Pancreatic secretion
    K01242  CD38; ADP-ribosyl cyclase 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K01242  CD38; ADP-ribosyl cyclase 1
   00536 Glycosaminoglycan binding proteins
    K01242  CD38; ADP-ribosyl cyclase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.20  2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
     K01242  CD38; ADP-ribosyl cyclase 1
 3. Hydrolases
  3.2  Glycosylases
   3.2.2  Hydrolysing N-glycosyl compounds
    3.2.2.6  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
     K01242  CD38; ADP-ribosyl cyclase 1
CD molecules [BR:ko04090]
 Proteins
  K01242  CD38; CD38 antigen (p45)
Glycosaminoglycan binding proteins [BR:ko00536]
 Hyaluronan
  Cell surface receptors
   K01242  CD38; ADP-ribosyl cyclase 1
Other DBs
RN: R00102 R00119 R10629 R10630 R10631 R10632
GO: 0050135
Genes
HSA: 952(CD38)
PTR: 745433(CD38)
PPS: 100974952(CD38)
GGO: 101149825(CD38)
PON: 100457558(CD38)
NLE: 100606960(CD38)
MCC: 714399(CD38)
MCF: 102126394(CD38)
CSAB: 103246326(CD38)
CATY: 105579036(CD38)
PANU: 101022305(CD38)
RRO: 104658170(CD38)
RBB: 108531741(CD38)
TFN: 117085174(CD38)
PTEH: 111539166(CD38)
CJC: 100387937(CD38)
SBQ: 101036203(CD38)
MMUR: 105856078(CD38)
MMU: 12494(Cd38)
MCAL: 110294426(Cd38)
MPAH: 110330967(Cd38)
RNO: 25668(Cd38)
MCOC: 116070680(Cd38)
MUN: 110559148(Cd38)
CGE: 100773187(Cd38)
PLEU: 114687856 114709225(Cd38)
NGI: 103728882(Cd38)
HGL: 101720283(Cd38)
CCAN: 109691561(Cd38)
OCU: 100009409(CD38)
TUP: 102480083(CD38)
CFA: 403756(CD38)
VVP: 112919984(CD38)
VLG: 121489687(CD38)
AML: 100481326(CD38)
UMR: 103658362(CD38)
UAH: 113266704(CD38)
ORO: 101364829(CD38)
ELK: 111149296
MPUF: 101685175(CD38)
EJU: 114196716(CD38)
MLX: 118010687(CD38)
FCA: 101101308(CD38)
PYU: 121038074(CD38)
PTG: 102955186(CD38)
PPAD: 109269635(CD38)
AJU: 106975653(CD38)
HHV: 120237985(CD38)
BTA: 327677(CD38)
BOM: 102273331(CD38)
BIU: 109560687(CD38)
BBUB: 102401480(CD38)
CHX: 102172881(CD38)
ODA: 120861630(CD38)
CCAD: 122428274(CD38)
SSC: 100511702(CD38)
CFR: 102508026(CD38)
CBAI: 105083239(CD38)
CDK: 105098339(CD38)
BACU: 103020545(CD38)
LVE: 103087769(CD38)
OOR: 101284537(CD38)
DLE: 111171401(CD38)
PCAD: 102981972(CD38)
ECB: 100068959(CD38)
EPZ: 103565759(CD38)
EAI: 106827091(CD38)
MYB: 102252244(CD38)
MYD: 102759158(CD38)
MMYO: 118666935(CD38)
HAI: 109372167(CD38)
DRO: 112316692(CD38)
SHON: 118986595(CD38)
AJM: 119035514(CD38)
MMF: 118641660(CD38)
PALE: 102889755(CD38)
PGIG: 120582820(CD38)
RAY: 107507351(CD38)
MJV: 108408183(CD38)
LAV: 100660287(CD38)
TMU: 101346368
MDO: 103094598(CD38)
SHR: 105751033(CD38)
PCW: 110212844(CD38)
OAA: 100074315(CD38)
GGA: 422827(CD38)
PCOC: 116225812
MGP: 100548136(CD38)
CJO: 107313951(CD38)
NMEL: 110398571(CD38)
ACYG: 106033418(CD38)
TGU: 101232999(CD38)
LSR: 110484008
SCAN: 103824319
PMOA: 120497360(CD38)
GFR: 102032646(CD38)
FAB: 101813225(CD38)
PHI: 102100836(CD38)
PMAJ: 107203546
CCAE: 111928170
CCW: 104690901(CD38)
ETL: 114061141
FPG: 101912278(CD38)
FCH: 102048375
EGZ: 104134477(CD38)
NNI: 104010763(CD38)
ACUN: 113479380
PADL: 103916996(CD38)
AAM: 106498697
NPD: 112958546
CPOO: 109322366(CD38)
GGN: 109304108
PSS: 102444963(CD38)
CMY: 102933862(CD38)
CPIC: 101935553
TST: 117878308
CABI: 116821059(CD38)
ACS: 100566030(cd38)
PVT: 110085956(CD38)
PBI: 103059310
PMUR: 107292463
TSR: 106543891(CD38)
PGUT: 117660712
PMUA: 114604446
ZVI: 118084020(CD38)
GJA: 107120012(CD38)
XLA: 100036901(cd38.L)
XTR: 496666(cd38)
NPR: 108799313
DRE: 101886891
SANH: 107693813
SGH: 107568972
CAUA: 113075268
AMEX: 103029242
HCQ: 109517521
SALP: 111953730
ELS: 105031580
RTP: 109917306
BFO: 118405736
APLC: 110981710
PCAN: 112555871
PMAX: 117342726
NVE: 5505197
ADF: 107339424
AMIL: 114961589
SPIS: 111329655
DGT: 114519185
 » show all
Reference
PMID:2319135
  Authors
Jackson DG, Bell JI
  Title
Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation.
  Journal
J Immunol 144:2811-5 (1990)
  Sequence
[hsa:952]
Reference
  Authors
Malavasi F, Deaglio S, Funaro A, Ferrero E, Horenstein AL, Ortolan E, Vaisitti T, Aydin S
  Title
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology.
  Journal
Physiol Rev 88:841-86 (2008)
DOI:10.1152/physrev.00035.2007

KEGG   ORTHOLOGY: K18152
Entry
K18152                      KO                                     

Symbol
BST1, CD157
Name
ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map04970  Salivary secretion
map04972  Pancreatic secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
 09150 Organismal Systems
  09154 Digestive system
   04970 Salivary secretion
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
   04972 Pancreatic secretion
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.20  2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
     K18152  BST1, CD157; ADP-ribosyl cyclase 2
 3. Hydrolases
  3.2  Glycosylases
   3.2.2  Hydrolysing N-glycosyl compounds
    3.2.2.6  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
     K18152  BST1, CD157; ADP-ribosyl cyclase 2
CD molecules [BR:ko04090]
 Proteins
  K18152  CD157, BST1; bone marrow stromal cell antigen 1
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
 Enzymes
  K18152  BST1, CD157; ADP-ribosyl cyclase 2
Other DBs
RN: R00102 R00119 R10629 R10630 R10631 R10632
GO: 0050135
Genes
HSA: 683(BST1)
PTR: 461126(BST1)
PPS: 100972434(BST1)
GGO: 101145401(BST1)
PON: 100174150(BST1)
NLE: 100606064(BST1)
MCC: 722848(BST1)
MCF: 101926698(BST1)
CSAB: 103246328(BST1)
CATY: 105579041(BST1)
PANU: 101017008(BST1)
RRO: 104658167(BST1)
RBB: 108531746(BST1)
TFN: 117085172(BST1)
PTEH: 111539163(BST1)
CJC: 100402445(BST1)
SBQ: 101035567(BST1)
MMUR: 105856080(BST1)
MMU: 12182(Bst1)
MCAL: 110294333(Bst1)
MPAH: 110330979(Bst1)
RNO: 81506(Bst1)
MCOC: 116070677(Bst1)
MUN: 110559149(Bst1)
CGE: 100773468(Bst1)
PLEU: 114709224(Bst1)
NGI: 103728884(Bst1)
HGL: 101713685(Bst1)
CCAN: 109691564(Bst1)
OCU: 100351817(BST1)
TUP: 102468679(BST1)
CFA: 488820(BST1)
VVP: 112919977(BST1)
VLG: 121489283(BST1)
AML: 100463977(BST1)
UMR: 103658313(BST1)
UAH: 113266702(BST1)
ORO: 101365133(BST1)
ELK: 111149117
MPUF: 101684892(BST1)
EJU: 114198536(BST1)
MLX: 118010690(BST1)
FCA: 101101052(BST1)
PYU: 121038087(BST1)
PTG: 102962771(BST1)
PPAD: 109269636(BST1)
AJU: 106975627(BST1)
HHV: 120237994(BST1)
BTA: 616757(BST1)
BOM: 102271683(BST1)
BIU: 109560088(BST1)
BBUB: 102400853(BST1)
CHX: 102169848(BST1)
OAS: 101116575(BST1) 114115251
ODA: 120861770(BST1)
CCAD: 122428330(BST1)
SSC: 100625942(BST1)
CFR: 102508256(BST1)
CBAI: 105083238(BST1)
CDK: 105098338(BST1)
BACU: 103000954(BST1)
LVE: 103088314(BST1)
OOR: 101284786(BST1)
DLE: 111171425(BST1)
PCAD: 102982819(BST1)
ECB: 100068968(BST1)
EPZ: 103565758(BST1)
EAI: 106827092(BST1)
MYB: 102252530(BST1)
MYD: 102770056(BST1)
MMYO: 118666927(BST1)
HAI: 109372831(BST1)
DRO: 112316691(BST1)
SHON: 118989556(BST1)
AJM: 119035581(BST1)
MMF: 118615378(BST1)
PALE: 102884937(BST1)
PGIG: 120582708(BST1)
RAY: 107507352(BST1)
MJV: 108403411(BST1)
TOD: 119260888(BST1)
LAV: 100659997(BST1)
TMU: 101346112
MDO: 100015733(BST1)
SHR: 100915627(BST1)
PCW: 110212831(BST1)
OAA: 100079912(BST1)
GGA: 422828(BST1)
PCOC: 116225809(BST1)
MGP: 100546297
CJO: 107313950(BST1)
NMEL: 110398576
APLA: 101799363(BST1)
ACYG: 106035386(BST1)
TGU: 100224783(BST1)
LSR: 110484039
SCAN: 103824309(BST1)
PMOA: 120497359
GFR: 102032481(BST1)
FAB: 101808664(BST1)
PHI: 102101014(BST1)
PMAJ: 107203272
CCAE: 111928172
CCW: 104690721
ETL: 114061133(BST1)
FPG: 101917967(BST1)
FCH: 102048871
CLV: 102089855(BST1)
EGZ: 104134476(BST1)
NNI: 104010764(BST1)
ACUN: 113479383(BST1)
PADL: 103916997(BST1)
AAM: 106498751
NPD: 112958511
ASN: 102376962(BST1)
AMJ: 102559494(BST1)
CPOO: 109322214(BST1)
GGN: 109303956
PSS: 102444728(BST1)
CMY: 102933631(BST1)
CPIC: 101935271
TST: 117878553
CABI: 116821061(BST1)
XLA: 101027297(bst1.L)
XTR: 101733556
NPR: 108799310(BST1)
AANG: 118226015
PSPA: 121324571
ARUT: 117420417
RTP: 109917325
BBEL: 109465410
APLC: 110977913
SKO: 100370260
CRG: 105319809
PMAX: 117342638
ATEN: 116291709
ADF: 107340996
AMIL: 114948060
 » show all
Reference
PMID:8202488
  Authors
Kaisho T, Ishikawa J, Oritani K, Inazawa J, Tomizawa H, Muraoka O, Ochi T, Hirano T
  Title
BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth.
  Journal
Proc Natl Acad Sci U S A 91:5325-9 (1994)
DOI:10.1073/pnas.91.12.5325
  Sequence
[hsa:683]
Reference
  Authors
Quarona V, Zaccarello G, Chillemi A, Brunetti E, Singh VK, Ferrero E, Funaro A, Horenstein AL, Malavasi F
  Title
CD38 and CD157: a long journey from activation markers to multifunctional molecules.
  Journal
Cytometry B Clin Cytom 84:207-17 (2013)
DOI:10.1002/cyto.b.21092
Reference
  Authors
Ortolan E, Vacca P, Capobianco A, Armando E, Crivellin F, Horenstein A, Malavasi F
  Title
CD157, the Janus of CD38 but with a unique personality.
  Journal
Cell Biochem Funct 20:309-22 (2002)
DOI:10.1002/cbf.978
  Sequence
[hsa:683]

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