KEGG ORTHOLOGY: K01542

ORTHOLOGY: K01542

Entry

K01542                      KO

Symbol

ATP4A

Name

H+/K+-exchanging ATPase subunit alpha [EC:7.2.2.19]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04966

Collecting duct acid secretion

map04971

Gastric acid secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K01542  ATP4A; H+/K+-exchanging ATPase subunit alpha
09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    K01542  ATP4A; H+/K+-exchanging ATPase subunit alpha
  09155 Excretory system
   04966 Collecting duct acid secretion
    K01542  ATP4A; H+/K+-exchanging ATPase subunit alpha
Enzymes [BR:ko01000]
7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.19  H+/K+-exchanging ATPase
     K01542  ATP4A; H+/K+-exchanging ATPase subunit alpha

Other DBs

GO:

0008900

TC:

3.A.3.1.2

Genes

HSA:	495(ATP4A)

PTR:	747915(ATP4A)

PPS:	100980523(ATP4A)

GGO:	101138827(ATP4A)

PON:	100435235(ATP4A)

PPYG:

129020752(ATP4A)

NLE:	100593416(ATP4A)

HMH:	116478910(ATP4A)

SSYN:

129461144(ATP4A)

MCC:	100426215(ATP4A)

MCF:	102124568(ATP4A)

MTHB:

126941882

MNI:	105495516(ATP4A)

CSAB:

103234521(ATP4A)

CATY:

105578179(ATP4A)

PANU:

101008375(ATP4A)

TGE:	112613167(ATP4A)

MLEU:

105541294(ATP4A)

RRO:	104667094(ATP4A)

RBB:	108512346(ATP4A)

TFN:	117092362(ATP4A)

PTEH:

111529928(ATP4A)

CANG:

105516102(ATP4A)

CJC:	100405348(ATP4A)

SBQ:	101047734(ATP4A)

CIMI:

108286357(ATP4A)

ANAN:

105707158(ATP4A)

CSYR:

103273562(ATP4A)

MMUR:

105876924(ATP4A)

LCAT:

123624471(ATP4A)

ERUF:

138374294(ATP4A)

PCOQ:

105816253(ATP4A)

OGA:	100941378(ATP4A)

MMU:	11944(Atp4a)

MCAL:

110297674(Atp4a)

MPAH:

110316696(Atp4a)

RNO:	24216(Atp4a)

MCOC:

116101990(Atp4a)

ANU:	117712562(Atp4a)

ASYL:

127682822(Atp4a)

MMIU:

308413440(ATP4A)

MUN:	110551638(Atp4a)

CGE:	100767384(Atp4a)

MAUA:

101834043(Atp4a)

PROB:

127238907(Atp4a)

PLEU:

114681649(Atp4a)

PMAV:

102924452(Atp4a)

MORG:

121449422(Atp4a)

MFOT:

126486695

AAMP:

119821880(Atp4a)

CNL:	130865457(Atp4a)

NGI:	103729925(Atp4a)

HGL:	101724247(Atp4a)

CPOC:

100732743(Atp4a)

CCAN:

109689140(Atp4a)

DORD:

105993074(Atp4a)

DSP:	122097466(Atp4a)

DMER:

138811080(Atp4a)

PLOP:

125368255(Atp4a)

NCAR:

124966338

SVUL:

306649124(ATP4A)

MMMA:

107151750(Atp4a)

ITI:	101964579(Atp4a)

SCIL:

308637865(ATP4A)

MAVE:

308268433(ATP4A)

OCU:	100009279(ATP4A)

OPI:	101532969(ATP4A)

OCZ:	121153890(ATP4A)

TUP:	102480463(ATP4A)

GVR:	103601451(ATP4A)

CFA:	431686(ATP4A)

CLUD:

112643525(ATP4A)

VVP:	112928326(ATP4A)

VLG:	121479246(ATP4A)

NPO:	129500580(ATP4A)

AML:	100465081(ATP4A)

UMR:	103682508(ATP4A)

UAH:	113244763(ATP4A)

UAR:	123793887(ATP4A)

ELK:

111161471

LLV:

125088370

MPUF:

106003277(ATP4A)

MNP:	132006068(ATP4A)

MLK:	131818496(ATP4A)

NVS:	122911556(ATP4A)

MMAQ:

308358802(ATP4A)

ORO:	101368519(ATP4A)

EJU:	114204018 114224363(ATP4A)

ZCA:	113935424(ATP4A)

MLX:	118022790(ATP4A)

MANO:

123856039(ATP4A)

NSU:	110590090(ATP4A)

LWW:	102728557(ATP4A)

FCA:	101100771(ATP4A)

PCOO:

112851271(ATP4A)

PBG:	122495067(ATP4A)

PVIV:

125153523(ATP4A)

LRUF:

124511813

LGF:	123578213(ATP4A)

AJU:

106974749

PTG:	102964110(ATP4A)

PPAD:

109251505(ATP4A)

PUC:

125915911

PLEZ:

122208198(ATP4A)

HHV:	120243462(ATP4A)

CCRU:

144239595(ATP4A)

BTA:	521163(ATP4A)

BOM:	102273487(ATP4A)

BIU:	109571697(ATP4A)

BJV:	133229422(ATP4A)

BBUB:

102415959(ATP4A)

BKE:	129630882(ATP4A)

BBIS:

104995244(ATP4A)

CHX:	102180792(ATP4A)

OAS:	101116166(ATP4A)

OCAN:

138418715(ATP4A)

BTAX:

128062999(ATP4A)

CSUM:

138095764(ATP4A)

ODA:	120873301(ATP4A)

CCAD:

122421382(ATP4A)

MREE:

136161184(ATP4A)

OVR:	110123675(ATP4A)

MBEZ:

129546062(ATP4A)

SSC:	397552(ATP4A)

CFR:	102505116(ATP4A)

CBAI:

105065041(ATP4A)

CDK:	105088096(ATP4A)

VPC:	102530856(ATP4A)

BACU:

103012701(ATP4A)

BMUS:

118884801(ATP4A)

LVE:	103071724(ATP4A)

OOR:	101276734(ATP4A)

LALB:

132509544(ATP4A)

GMF:	115862583(ATP4A)

DDP:	132416111(ATP4A)

SCOO:

307179006(ATP4A)

PCRS:

137215221(ATP4A)

DLE:	111181140(ATP4A)

PCAD:

102994597(ATP4A)

PSIU:

116744556(ATP4A)

PPHC:

136141203(ATP4A)

NASI:

112392228(ATP4A)

HAMP:

307066046(ATP4A)

ECB:	100147108(ATP4A)

EPZ:	103560041(ATP4A)

EAI:	106829240(ATP4A)

MYB:	102249396(ATP4A)

MYD:	102753224(ATP4A)

MMYO:

118674738(ATP4A)

MLF:	102427161(ATP4A)

MDT:	132216993(ATP4A)

MYUM:

138996781(ATP4A)

PKL:	118720628(ATP4A)

EFUS:

103284507(ATP4A)

POTS:

308236340(ATP4A)

MNA:	107543398(ATP4A)

DRO:	112320122(ATP4A)

SHON:

118982540(ATP4A)

AJM:	119044216(ATP4A)

PDIC:

114511655(ATP4A)

PHAS:

123823744(ATP4A)

MMF:	118638589(ATP4A)

PPAM:

129083092(ATP4A)

HAI:	109372015(ATP4A)

RFQ:	117035341(ATP4A)

RHII:

308489977(ATP4A)

PALE:

102882245(ATP4A)

PGIG:

120592418(ATP4A)

PVP:	105306638(ATP4A)

RAY:	107497657(ATP4A)

MJV:	108398957(ATP4A)

TOD:	119248621(ATP4A)

SARA:

101559007(ATP4A)

SFUM:

130043943(ATP4A)

SETR:

126028489(ATP4A)

LAV:	100670470(ATP4A)

TMU:

101350003

ETF:	101656652(ATP4A)

DNM:	101442103(ATP4A)

MDO:	100013166(ATP4A)

GAS:	123243026(ATP4A)

SHR:	100926385(ATP4A)

AFZ:

127556065

PCW:	110201386(ATP4A)

TVP:	118839023(ATP4A)

MLAO:

141509382(ATP4A)

CJO:

107307398

APLA:

119714257(ATP4A)

AACU:

137848812(ATP4A)

OJA:	118159813(ATP4A)

BCLA:

308454872(ATP4A)

ABRC:

308186593(ATP4A)

CATA:

118261601 118261629(ATP4A)

AFUL:

116501745(ATP4A)

TGU:	115492958(ATP4A)

LSR:

110483038

VMC:	128803008(ATP4A)

VCHA:

128782832(ATP4A)

AIB:	137465810 137467606

PMOA:

120510986

ATRC:

139586089

MATE:

118701183(ATP4A)

OMA:

130263330

ACOE:

138101612

ZLE:	135461007(ATP4A)

SVG:	106864376(ATP4A)

LCAI:

146423527(LOC146423527) 146423530(ATP4A)

CFAI:

136284510 136304912

CCIC:

134055861(ATP4A)

PECH:

308232716(ATP4A)

FPG:	101911437(ATP4A)

FCH:	102055866(ATP4A)

FRS:	119144541(ATP4A)

SURA:

HLE:

AGEN:

HHAR:

BBUT:

142025945(ATP4A)

IIN:	128978656(ATP4A)

NNI:

104011769

PLEC:

309604273(LOC309604273)

PARX:

142051358(ATP4A)

AFOR:

103901363

CBOR:

142074363(ATP4A)

CBOY:

140645006(ATP4A)

MAME:

142403297(ATP4A)

CNIC:

136000746(ATP4A)

NMAY:

308051190(LOC308051190) 308051205(ATP4A)

CUCA:

128849903(ATP4A)

PCUR:

138734872(ATP4A)

GAME:

129196993(ATP4A)

HEK:	139790662(ATP4A)

CVF:

104294498

RTD:	128903884(ATP4A)

CRID:

134509802(ATP4A)

LMIC:

141735298(ATP4A)

NARQ:

141478562(ATP4A)

AROW:

112963221

NPD:	112957892(ATP4A)

DNE:

112996443

ASN:	102387741(ATP4A)

AMJ:

109283416

PSS:	102450978(ATP4A)

CIZ:	142003790(ATP4A)

CMY:	102936245(ATP4A)

CCAY:

125625842(ATP4A)

LKP:	140902845(ATP4A)

NDS:	141977612(ATP4A)

DCC:	119847678(ATP4A)

CPIC:

101946000(ATP4A)

TST:	117869762(ATP4A)

EOB:	135892187(ATP4A)

CABI:

116833676(ATP4A)

MRV:	120390272(ATP4A)

EMQ:	137160054(ATP4A)

ACS:	100563553(atp4a)

ASAO:

132780244(ATP4A)

PVT:	110089078(ATP4A)

SUND:

121915588(ATP4A)

PBI:	103054731(ATP4A)

PMUR:

107292625(ATP4A)

CTIG:

120300069(ATP4A)

TSR:

106548299

PGUT:

117669240(ATP4A)

PCAE:

139321347(ATP4A)

APRI:

131204521(ATP4A)

PTEX:

113448214(ATP4A)

NSS:	113423747(ATP4A)

VKO:	123019395(ATP4A)

PMUA:

114602396(ATP4A)

PRAF:

128418525(ATP4A)

ZVI:	118087382(ATP4A)

HCG:	128332837(ATP4A)

GJA:	107116203(ATP4A)

STOW:

125434809(ATP4A)

EMC:	129343052(ATP4A)

XLA:	108696872 733327(atp4a.S)

XTR:	100488221(atp4a)

NPR:	108797188(ATP4A)

RTEM:

120916253(ATP4A)

ACAT:

141110332(ATP4A)

PADS:

140340436(ATP4A)

BBUF:

120986820(ATP4A)

DTC:	141085179(ATP4A)

HSQ:	130294390(ATP4A)

PCOB:

134966889(ATP4A)

PWL:	138246521(ATP4A)

MUO:	115476325(ATP4A)

GSH:	117345556(ATP4A)

TROS:

TDW:

IPU:

IFU:

PHYP:

113532853(atp4a)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:	113571928(atp4a)

CHAR:

105891898

SPIL:

134082744

ASAD:

121720882

NCC:	104957693(atp4a)

TBEN:

117480677

CGOB:

115021320(atp4a)

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

SVIT:

ECRA:

ESP:

PFLV:

114556886(atp4a)

PFLT:

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

TBU:	306744402(LOC306744402)

CVE:

AMIR:

MSAM:

SCHU:

EARM:

ALAT:

ASTR:

PKLU:

LCO:	104940311(atp4a)

AMMM:

307259136(LOC307259136)

MZE:

101464178

ONL:	100690043(atp4a)

OAU:

MCEP:

AOCE:

LCF:

POV:	109633020(atp4a)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

SDU:	111236799(atp4a)

SLAL:

111652775(atp4a)

XGL:

120784338

BPEC:

110171389(atp4a)

ENY:

140373595

MALB:

109967366(atp4a)

BSPL:

SJO:

SSCO:

TTY:

GMH:	115553894(atp4a)

ZFA:	307234233(LOC307234233)

SASA:

106577750 106605632

STRU:

115176661 115182575

OTW:	112227190 112245864

OMY:	100136301 110519929

OGO:	123997984 124005106

ONE:	115102130 115140890

OKI:	109900952 109901664

OKE:	118364085 118367644

OMM:	135520459 135522034

OCLA:

139390547 139423254

SALP:

111959186 111964878

SNH:	120031708 120048543

SFON:

129837229 129856825

CCLU:

121543053 121556072

ELS:	105019136(atp4a)

OEP:

134023417

SFM:	108919133(atp4a)

PKI:	111841121(atp4a)

AANG:

118211254

AROT:

135237877

CCOG:

133127017

LOC:	102687313(atp4a)

PSPA:

121299114

ARUT:

117434009 117968514

PSEX:

120541731

LCM:	102352096(ATP4A)

SCAU:

STOZ:

HAKA:

Reference

PMID:2160952

Authors

Maeda M, Oshiman K, Tamura S, Futai M

Title

Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control region.

Journal

J Biol Chem 265:9027-32 (1990)
DOI:10.1016/S0021-9258(19)38807-6

Sequence

[hsa:495]

All links

Ontology (2)   
   GO (1)   
   TC (1)   
Gene (622)   
   MGENES (193)   
   RefGene (422)   
   OC (7)   
All databases (624)   

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