KEGG   ORTHOLOGY: K02304
Entry
K02304                      KO                                     
Symbol
MET8
Name
precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
Pathway
map00860  Porphyrin metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01240  Biosynthesis of cofactors
Module
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K02304  MET8; precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     K02304  MET8; precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     K02304  MET8; precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Other DBs
RN: R02864 R03947
COG: COG1648
GO: 0043115 0004325
Genes
QSU: 111985287 112036963
SCE: YBR213W(MET8)
SEUB: DI49_1239
SPAO: SPAR_B03110
AGO: AGOS_AAR152W
ERC: Ecym_3081
KLA: KLLA0_C05544g
KMX: KLMA_10243(MET8)
LTH: KLTH0H06820g
VPO: Kpol_530p45
NCS: NCAS_0H01490(NCAS0H01490)
NDI: NDAI_0F01760(NDAI0F01760)
TPF: TPHA_0F02830(TPHA0F02830)
TBL: TBLA_0F02410(TBLA0F02410)
TDL: TDEL_0G03660(TDEL0G03660)
KAF: KAFR_0G02310(KAFR0G02310)
KNG: KNAG_0M00860(KNAG0M00860)
PIC: PICST_63116(MET8)
CAL: CAALFM_C307210WA(MET8)
SLB: AWJ20_4352(MET8)
NCR: NCU07585
NTE: NEUTE1DRAFT77927(NEUTE1DRAFT_77927)
MGR: MGG_17830
SSCK: SPSK_09667
MAW: MAC_04288
MAJ: MAA_02805
CMT: CCM_04648
BFU: BCIN_12g05710(Bcmet8)
MBE: MBM_00710
ANI: AN6710.2
ANG: ANI_1_278064(An07g02200)
ALUC: AKAW2_11934S(MET8)
ACHE: ACHE_60971S(MET8)
APUU: APUU_70240A(MET8)
ABE: ARB_00672
TVE: TRV_05014
PTE: PTT_11930
CNE: CNF00750
CNB: CNBF3830
TASA: A1Q1_04432
ABP: AGABI1DRAFT117978(AGABI1DRAFT_117978)
SCM: SCHCO_02607604(SCHCODRAFT_02607604)
MGL: MGL_2195
MRT: MRET_0314
 » show all
Reference
  Authors
Schubert HL, Raux E, Brindley AA, Leech HK, Wilson KS, Hill CP, Warren MJ
  Title
The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase.
  Journal
EMBO J 21:2068-75 (2002)
DOI:10.1093/emboj/21.9.2068
  Sequence
[sce:YBR213W]

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