KEGG   ORTHOLOGY: K04102
Entry
K04102                      KO                                     
Symbol
pht5
Name
4,5-dihydroxyphthalate decarboxylase [EC:4.1.1.55]
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00623  Phthalate degradation, phthalate => protocatechuate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K04102  pht5; 4,5-dihydroxyphthalate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.55  4,5-dihydroxyphthalate decarboxylase
     K04102  pht5; 4,5-dihydroxyphthalate decarboxylase
Other DBs
RN: R01635 R05375
GO: 0018796
Genes
SERA: Ser39006_004620
SERQ: CWC46_04620
RACE: JHW33_10315
ROX: BV494_11240
RVC: J9880_01820
EAME: GXP68_15290
RBAD: H2866_13170
DSO: A4U42_06935
DDQ: DDI_3865
BGJ: AWC36_14580
HAM: HALO0381
CNC: CNE_2c21240(phtD) CNE_BB2p00930(phtD)
BCEN: DM39_6345
BXE: Bxe_A2046
BXB: DR64_4202
BFN: OI25_6506
BPE: BP0683
BPC: BPTD_0690
BPER: BN118_3023
BPET: B1917_0469
BPEU: Q425_4290
BPAR: BN117_0384
BPA: BPP0387
BBR: BB0389
BPT: Bpet0251
BAV: BAV0612(phtD)
BHZ: ACR54_04438(pht5)
POL: Bpro_1912
PNA: Pnap_4626
VEI: Veis_2927
CTES: O987_21860
LIM: L103DPR2_01692(pht5_1) L103DPR2_02571(pht5_3)
MES: Meso_0812
AMIH: CO731_00161(pht5)
RHT: NT26_0606(phtD)
BRAD: BF49_1198
BARH: WN72_20660
MTUN: MTUNDRAET4_0231.1(phtD)
PHL: KKY_2552
PLEO: OHA_1_01088(pht5)
HDI: HDIA_0359(pht5_1) HDIA_4227(pht5_2) HDIA_4233(pht5_3)
MMED: Mame_05093(pht5)
LABT: FIU93_07215(pht3)
RUT: FIU92_10275(pht1)
CID: P73_2964
RID: RIdsm_00902(pht5)
ROT: FIV09_09515(pht1) FIV09_12220(pht4)
MMAN: MMAN_42200
MGAD: MGAD_32420
PAUT: Pdca_37810
SDYN: Mal52_39900(pht5)
AG: BAA02513(pht5)
 » show all
Reference
  Authors
Nomura Y, Nakagawa M, Ogawa N, Harashima S, Oshima Y
  Title
Genes in PHT plasmid encoding the initial degradation pathway of phthalate in Pseudomonas putida.
  Journal
J Ferment Bioeng 74:333-344 (1992)
DOI:10.1016/0922-338X(92)90028-S
  Sequence

KEGG   ENZYME: 4.1.1.55
Entry
EC 4.1.1.55                 Enzyme                                 
Name
4,5-dihydroxyphthalate decarboxylase;
4,5-dihydroxyphthalate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Reaction(IUBMB)
4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2 [RN:R01635]
Reaction(KEGG)
R01635;
(other) R05375
Substrate
4,5-dihydroxyphthalate [CPD:C03233]
Product
3,4-dihydroxybenzoate [CPD:C00230];
CO2 [CPD:C00011]
History
EC 4.1.1.55 created 1972
Pathway
ec00624  Polycyclic aromatic hydrocarbon degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04102  4,5-dihydroxyphthalate decarboxylase
Genes
SERASer39006_004620
SERQCWC46_04620
RACEJHW33_10315
ROXBV494_11240
RVCJ9880_01820
EAMEGXP68_15290
RBADH2866_13170
DSOA4U42_06935
DDQDDI_3865
BGJAWC36_14580
BNGEH206_18220
BIZHC231_19335
PAGGAL522_09720
PAGCBEE12_12190
PANSFCN45_05510
LRZBJI69_16450
PLULFOB45_02780
PEZHWQ56_18630 HWQ56_18655
HALCEY643_17420
HAMHALO0381
HSRHSBAA_48210
HMDCTT34_16725
HSXHNO51_14945
MPRFJ8N69_04565
MGEOCFI10_14935
RPFRpic12D_2784 Rpic12D_4963
CNCCNE_2c21240(phtD) CNE_BB2p00930(phtD)
CCUPBKK81_20070
CUPBKK80_21735
CUUBKK79_26900
BVIBcep1808_4268 Bcep1808_4307
BCENDM39_6345
BMUBmul_4781 Bmul_4810
BMKDM80_3999 DM80_4025
BYIBYI23_B001670 BYI23_D008110 BYI23_D008200
BUEBRPE67_BCDS04060 BRPE67_DCDS10030 BRPE67_DCDS10120
BXEBxe_A2046
BXBDR64_4202
BPYBphyt_2225
BUZAYM40_11985
BFNOI25_6506
BCAIK788_0001936 K788_0001942 K788_0002080 K788_0006046 K788_0006051 K788_0006973
PSPWBJG93_04710 BJG93_19260 BJG93_19295
PHSC2L64_23710 C2L64_42425 C2L64_43205 C2L64_49450
PTERC2L65_26855 C2L65_39465 C2L65_40380 C2L65_41300 C2L65_41330
PGPCUJ91_22190 CUJ91_24950 CUJ91_24980
PMEGFNZ07_20470
PTROG5S35_28065 G5S35_28090 G5S35_28155 G5S35_35520
PGISI6I06_25480 I6I06_25485
PACPFAZ97_21795 FAZ97_34640 FAZ97_34675
PACSFAZ98_14410 FAZ98_23655 FAZ98_23675 FAZ98_25920 FAZ98_25950 FAZ98_30425
PEWKZJ38_26715 KZJ38_27355
PNRAT302_18000
BUOBRPE64_DCDS03540 BRPE64_DCDS03640 BRPE64_DCDS07090
BPEBP0683
BPCBPTD_0690
BPERBN118_3023
BPETB1917_0469
BPEUQ425_4290
BPARBN117_0384
BPABPP0387
BBHBN112_3024
BBRBB0389
BBMBN115_0374
BBXBBS798_0385
BPTBpet0251
BAVBAV0612(phtD)
BHZACR54_04438(pht5)
BBROBAU06_03755
BFZBAU07_03955 BAU07_15860
BPDZBBN53_00960 BBN53_03780
BOHAKI39_11040 AKI39_14195 AKI39_21325
BGMCAL15_18115
ADTAPT56_20790
ACHRC2U31_19610 C2U31_25990
CDNBN940_06901
AFAUZ73_14455
PIGEGT29_02190 EGT29_02800 EGT29_03400 EGT29_05080 EGT29_05090 EGT29_08040 EGT29_16085 EGT29_21775 EGT29_23305 EGT29_27680 EGT29_28195
PACRFXN63_13475
RHYRD110_17805 RD110_25750
POLBpro_1912
PNAPnap_4626
POSDT070_20415
POOF7R28_10160
ACIDCBP33_05525
ACIPCBP36_05975 CBP36_20405
ACINCBP34_05360
ACISCBP35_12970
VEIVeis_2927
DELDelCs14_1656
CTTCtCNB1_1485
CTESO987_21860
OTKC6570_10590
LIML103DPR2_01692(pht5_1) L103DPR2_02571(pht5_3)
HYRBSY239_3463
HYNF9K07_06630 F9K07_22620 F9K07_27555
HTNKI616_03510 KI616_03530
DIHG7047_04615 G7047_04650 G7047_06770 G7047_26535 G7047_26540
STHMIS481_16085 IS481_17590
HRBHrubri_2651
MASWAM586_27415 AM586_27620 AM586_27685
DUGHH213_15575 HH213_15610
SUTKFG381_12310
MESRFGU64_18900 FGU64_18930
MESMeso_0812
AAKAA2016_6290
AMIHCO731_00161(pht5)
PHTBLM14_15135
ORMHTY61_15040
EMXFKV68_30050 FKV68_30095 FKV68_30155
ALFCFBP5473_19340
ARUIG6M88_16515
AVQHRR99_16800
RJGCCGE525_28185
RHRCKA34_23245
RIIFFM53_025260
RRGJ3P73_26000
NEOCYG48_17355
NENNCHU2750_48890
RHTNT26_0606(phtD)
ABAWD5400_03695 D5400_20240
BRCBCCGELA001_15995
BRADBF49_1198
BICLMTR13_15100
BRQCIT40_12020
BGZXH91_21280
BSYMCIT39_11260
BBETF8237_02990
BARHWN72_20660
TRBHB776_05180
BVVBHK69_01795
BOIBLM15_12195 BLM15_16195
BOFFQV39_17840
BAPIBBC0122_007930
STARG3545_14630 G3545_20000 G3545_21650
MOCBB934_24465
MICOGDR74_15635
MTUNMTUNDRAET4_0231.1(phtD)
MLGCWB41_10080
RHZRHPLAN_02150 RHPLAN_05430 RHPLAN_08180 RHPLAN_09030 RHPLAN_10250 RHPLAN_10400 RHPLAN_10470 RHPLAN_21070 RHPLAN_23490 RHPLAN_27380 RHPLAN_27510 RHPLAN_30240 RHPLAN_30440 RHPLAN_33070 RHPLAN_33370 RHPLAN_34990 RHPLAN_47510 RHPLAN_51220 RHPLAN_59590 RHPLAN_64790 RHPLAN_68290
PHLKKY_2552
DSALK1X15_01465
PLEOOHA_1_01088(pht5)
HDIHDIA_0359(pht5_1) HDIA_4227(pht5_2) HDIA_4233(pht5_3)
MMEDMame_05093(pht5)
PSINCAK95_02200 CAK95_15630 CAK95_24720
TSOIZ6_03430 IZ6_06900
LABTFIU93_07215(pht3)
BRLBZG35_10665 BZG35_10690
BGOEIFJ75_11330
RUAD1823_14495
RUTFIU92_10275(pht1)
RPONG3256_05245
CIDP73_2964
CEHCEW89_13900
TPROGa0080559_TMP5107
PABYGa0080574_TMP2099
RIDRIdsm_00902(pht5)
AHTANTHELSMS3_01342 ANTHELSMS3_01357 ANTHELSMS3_04764
OCDFHY55_04875
ROTFIV09_09515(pht1) FIV09_12220(pht4)
RMHLVO79_19210
PKDF8A10_01145
PPANESD82_01060
TAWEI545_11275
PGVSL003B_1108
HDHG5B40_16620
CBOTATE48_17510
NORFA702_15525
NDRHT578_08890
SPHRBSY17_4180 BSY17_4184
SHYDCJD35_19400 CJD35_19420 CJD35_19635
SPHJBSL82_13980
POTE2E27_18190
RGIRGI145_16725 RGI145_16755 RGI145_21160
ROSCTJ15_00850
RMUCFOB66_01840
RMTIAI58_16225 IAI58_18390
SRFLHU95_07655
NCBC0V82_20115 C0V82_20160
BACAFAY30_04565
PARHI5S86_11330 I5S86_11355
SCIAHUG15_03360
PNPIJ22_14400 IJ22_32350
PYGAWM70_00715
COHEAV92_02555
AACOK1I37_00655
ACOLK5I23_05550
FWADCMF_22740
MMANMMAN_42200
MGADMGAD_32420
ROAPd630_LPD00211
SMALSMALA_3532 SMALA_7792 SMALA_7812
SSOII1A49_21425 I1A49_42800
SGMGCM10017557_73370 GCM10017557_73390 GCM10017557_73400
SAUOBV401_21100
SNQCP978_01370 CP978_01385
SPRACP972_27990 CP972_28105
MSEDE3O41_13970
SALCC2138_00905
ARZAUT26_02345 AUT26_19520
PUEFV140_21270
NPSKRR39_10735
NGNLCN96_16605
AACDLWP59_07660
PAUTPdca_37810
PMADBAY61_22330
PSUUPsuf_075990
JTLM6D93_02965
RMARGBA65_17485
SBAEDSM104329_03696
SDYNMal52_39900(pht5)
AMOAnamo_1078
HSNDV733_04370 DV733_05155
HRRHZS55_08175 HZS55_08200
HPELHZS54_08830 HZS54_08855
HLTI7X12_06080
HALQHrr1229_000835 Hrr1229_000860 Hrr1229_001505
HSSJ7656_11255 J7656_11285
SRUBC2R22_03385
HDFAArcSl_0383 AArcSl_0384 AArcSl_0387
SSHIJ5U23_01790 J5U23_01815 J5U23_01825
SULOGFS33_09975 GFS33_10035 GFS33_10225
 » show all
Reference
1  [PMID:16748829]
  Authors
Ribbons DW, Evans WC.
  Title
Oxidative metabolism of phthalic acid by soil pseudomonads.
  Journal
Biochem J 76:310-8 (1960)
DOI:10.1042/bj0760310
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.55
IUBMB Enzyme Nomenclature: 4.1.1.55
ExPASy - ENZYME nomenclature database: 4.1.1.55
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.1.55
BRENDA, the Enzyme Database: 4.1.1.55
CAS: 37290-48-5

KEGG   REACTION: R01635
Entry
R01635                      Reaction                               
Name
4,5-Dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Definition
4,5-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2
Equation
Reaction class
RC00390  C00230_C03233
Enzyme
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00623  Phthalate degradation, phthalate => protocatechuate
Orthology
K04102  4,5-dihydroxyphthalate decarboxylase [EC:4.1.1.55]
Other DBs
RHEA: 24187

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