KEGG   ORTHOLOGY: K04117
Entry
K04117                      KO                                     
Symbol
aliB
Name
cyclohexanecarboxyl-CoA dehydrogenase [EC:1.3.99.-]
Pathway
map00362  Benzoate degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00540  Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K04117  aliB; cyclohexanecarboxyl-CoA dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.99  With unknown physiological acceptors
    1.3.99.-
     K04117  aliB; cyclohexanecarboxyl-CoA dehydrogenase
Other DBs
RN: R05619
Genes
PSET: THL1_3541
PSIL: PMA3_18700
MAD: HP15_4141
MSR: AU15_21950
MSX: AU14_15320
MARI: ACP86_11265 ACP86_20275
MSQ: BKP64_15425
ALC: OTEC02_08685
AEI: AOY20_11405
ARJ: DOM24_08435(aliB)
ALJ: G8D99_08360(aliB)
ASHA: G8E00_07725(aliB)
HSX: HNO51_18890(aliB)
HSV: HNO53_19140(aliB)
REH: H16_B1694(h16_B1694)
CTI: RALTA_B1487(badJ)
COX: E0W60_02405(aliB)
BCEN: DM39_6477(aliB)
BPSL: WS57_17370
BANN: JFN94_18815(aliB)
PARB: CJU94_39045(aliB)
PTRO: G5S35_36595(aliB)
PACP: FAZ97_31965(aliB)
PPNO: DA70_22575
PPNM: LV28_08145
PAPI: SG18_02570
PAND: DRB87_16945(aliB)
PFIB: PI93_009545(aliB)
ACHB: DVB37_17145(aliB)
POL: Bpro_5273
PNA: Pnap_2125
ACRA: BSY15_303(aliB)
VEI: Veis_4106
VBO: CKY39_28750(aliB)
CODO: LAD35_02815(aliB)
HPSE: HPF_12930(acdA4)
DIH: G7047_24810(aliB)
DAER: H9K75_12265(aliB)
LCH: Lcho_1187
AON: DEH84_15665(aliB)
EBA: ebA1959(badJ)
APET: ToN1_06890 ToN1_46740(aliB)
AZA: AZKH_3420(badJ)
AZD: CDA09_11760(aliB)
PLA: Plav_1771
RPA: RPA0652(aliB)
RPC: RPC_1034
RPD: RPD_1543
RPE: RPE_0613
RPT: Rpal_0719
VGO: GJW-30_1_01055(acrC_3)
XAU: Xaut_0913
RBM: TEF_19745
MALG: MALG_03754
SPSE: SULPSESMR1_04131(carC)
RID: RIdsm_05475(acdA_12)
PPAN: ESD82_07075(aliB)
HML: HmaOT1_17295(aliB)
RAP: RHOA_0347(aliB)
BACO: OXB_1161
VPN: A21D_02259(mmgC_2)
PASA: BAOM_1368(aliB)
AAD: TC41_1118
CEF: CE2779
CTER: A606_01870
CCOE: CETAM_10655(acrC)
ROP: ROP_46750
SALS: SLNWT_6897
NCA: Noca_4298
NML: Namu_0878
PDX: Psed_4099
PSEE: FRP1_16420
PAUT: Pdca_60280
HAU: Haur_5209
 » show all
Reference
  Authors
Pelletier DA, Harwood CS
  Title
2-Hydroxycyclohexanecarboxyl coenzyme A dehydrogenase, an enzyme characteristic of the anaerobic benzoate degradation pathway used by Rhodopseudomonas palustris.
  Journal
J Bacteriol 182:2753-60 (2000)
DOI:10.1128/JB.182.10.2753-2760.2000
Reference
  Authors
Hirakawa H, Hirakawa Y, Greenberg EP, Harwood CS
  Title
BadR and BadM Proteins Transcriptionally Regulate Two Operons Needed for Anaerobic Benzoate Degradation by Rhodopseudomonas palustris.
  Journal
Appl Environ Microbiol 81:4253-62 (2015)
DOI:10.1128/AEM.00377-15
  Sequence
[rpa:RPA0652]

KEGG   ORTHOLOGY: K19067
Entry
K19067                      KO                                     
Symbol
E1.3.8.11
Name
cyclohexane-1-carbonyl-CoA dehydrogenase [EC:1.3.8.11]
Pathway
map00362  Benzoate degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K19067  E1.3.8.11; cyclohexane-1-carbonyl-CoA dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.8  With a flavin as acceptor
    1.3.8.11  cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein)
     K19067  E1.3.8.11; cyclohexane-1-carbonyl-CoA dehydrogenase
Other DBs
RN: R10601
Genes
GME: Gmet_3307
GEO: Geob_2190
GBM: Gbem_3576
DML: Dmul_00970
SAT: SYN_02586
Reference
  Authors
Kung JW, Seifert J, von Bergen M, Boll M
  Title
Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus.
  Journal
J Bacteriol 195:3193-200 (2013)
DOI:10.1128/JB.00322-13
  Sequence
[sat:SYN_02586]

KEGG   ENZYME: 1.3.8.11
Entry
EC 1.3.8.11                 Enzyme                                 
Name
cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein);
aliB (gene name);
cyclohexane-1-carbonyl-CoA dehydrogenase (ambiguous)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With a flavin as acceptor
Sysname
cyclohexane-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase
Reaction(IUBMB)
cyclohexane-1-carbonyl-CoA + electron-transfer flavoprotein = cyclohex-1-ene-1-carbonyl-CoA + reduced electron-transfer flavoprotein [RN:R10601]
Reaction(KEGG)
R10601
Substrate
cyclohexane-1-carbonyl-CoA [CPD:C09823];
electron-transfer flavoprotein [CPD:C04253]
Product
cyclohex-1-ene-1-carbonyl-CoA [CPD:C09811];
reduced electron-transfer flavoprotein [CPD:C04570]
Comment
Contains FAD. The enzyme, characterized from the strict anaerobic bacterium Syntrophus aciditrophicus, is involved in production of cyclohexane-1-carboxylate, a byproduct produced by that organism during fermentation of benzoate and crotonate to acetate.
History
EC 1.3.8.11 created 2013, modified 2020
Pathway
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K19067  cyclohexane-1-carbonyl-CoA dehydrogenase
Genes
GMEGmet_3307
GEOGeob_2190
GBMGbem_3576
DMLDmul_00970
SATSYN_02586
Reference
1  [PMID:10781543]
  Authors
Pelletier DA, Harwood CS
  Title
2-Hydroxycyclohexanecarboxyl coenzyme A dehydrogenase, an enzyme characteristic of the anaerobic benzoate degradation pathway used by Rhodopseudomonas palustris.
  Journal
J Bacteriol 182:2753-60 (2000)
DOI:10.1128/JB.182.10.2753-2760.2000
Reference
2  [PMID:23667239]
  Authors
Kung JW, Seifert J, von Bergen M, Boll M
  Title
Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus.
  Journal
J Bacteriol 195:3193-200 (2013)
DOI:10.1128/JB.00322-13
  Sequence
[sat:SYN_02586]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.8.11
IUBMB Enzyme Nomenclature: 1.3.8.11
ExPASy - ENZYME nomenclature database: 1.3.8.11
BRENDA, the Enzyme Database: 1.3.8.11

KEGG   REACTION: R05619
Entry
R05619                      Reaction                               
Definition
Cyclohexane-1-carboxyl-CoA + Acceptor <=> Cyclohex-1-ene-1-carboxyl-CoA + Reduced acceptor
Equation
Comment
BadJ
Reaction class
RC02035  C09811_C09823
Enzyme
1.3.-.-
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00540  Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA
Orthology
K04117  cyclohexanecarboxyl-CoA dehydrogenase [EC:1.3.99.-]

KEGG   REACTION: R10601
Entry
R10601                      Reaction                               
Name
cyclohexane-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase
Definition
Cyclohexane-1-carboxyl-CoA + Electron-transferring flavoprotein <=> Cyclohex-1-ene-1-carboxyl-CoA + Reduced electron-transferring flavoprotein
Equation
Reaction class
RC02035  C09811_C09823
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K19067  cyclohexane-1-carbonyl-CoA dehydrogenase [EC:1.3.8.11]
Other DBs
RHEA: 38938

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