KEGG   ORTHOLOGY: K04141
Entry
K04141                      KO                                     
Symbol
ADRB1
Name
adrenergic receptor beta-1
Pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04261  Adrenergic signaling in cardiomyocytes
map04540  Gap junction
map04923  Regulation of lipolysis in adipocytes
map04924  Renin secretion
map04970  Salivary secretion
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04024 cAMP signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04022 cGMP-PKG signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04141  ADRB1; adrenergic receptor beta-1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04141  ADRB1; adrenergic receptor beta-1
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K04141  ADRB1; adrenergic receptor beta-1
   04924 Renin secretion
    K04141  ADRB1; adrenergic receptor beta-1
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04141  ADRB1; adrenergic receptor beta-1
  09154 Digestive system
   04970 Salivary secretion
    K04141  ADRB1; adrenergic receptor beta-1
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K04141  ADRB1; adrenergic receptor beta-1
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K04141  ADRB1; adrenergic receptor beta-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04141  ADRB1; adrenergic receptor beta-1
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    K04141  ADRB1; adrenergic receptor beta-1
Other DBs
GO: 0004940
TC: 9.A.14.3.11
Genes
HSA: 153(ADRB1)
PTR: 466206(ADRB1)
PPS: 100978740(ADRB1)
GGO: 101149664(ADRB1)
PON: 100441708(ADRB1)
NLE: 100606030(ADRB1)
MCC: 100426598(ADRB1)
MCF: 107126443(ADRB1)
CSAB: 103216543(ADRB1)
CATY: 105577918(ADRB1)
PANU: 110740390(ADRB1)
TGE: 112631736(ADRB1)
RRO: 104659193(ADRB1)
RBB: 108542470(ADRB1)
TFN: 117066654(ADRB1)
PTEH: 111538914(ADRB1)
CJC: 100387664(ADRB1)
MMUR: 105875389(ADRB1)
LCAT: 123650240(ADRB1)
OGA: 100940919(ADRB1)
MMU: 11554(Adrb1)
MCAL: 110285631(Adrb1)
MPAH: 110333803(Adrb1)
RNO: 24925(Adrb1)
MCOC: 116104027(Adrb1)
MUN: 110545114(Adrb1)
CGE: 113834807
MAUA: 101830640(Adrb1)
PLEU: 114697069(Adrb1)
MORG: 121454690(Adrb1)
AAMP: 119804182(Adrb1)
NGI: 103731758(Adrb1)
HGL: 101706546(Adrb1)
CPOC: 100379595(Adrb1)
CCAN: 109678400(Adrb1)
DSP: 122115801(Adrb1)
NCAR: 124985454
OCU: 100338084(ADRB1)
OPI: 101519586(ADRB1)
TUP: 102478713(ADRB1)
CFA: 493972(ADRB1)
CLUD: 112672364(ADRB1)
VVP: 112914728(ADRB1)
VLG: 121484304(ADRB1)
AML: 100471252(ADRB1)
UAH: 113251957(ADRB1)
UAR: 123795977(ADRB1)
ELK: 111145258
LLV: 125084967
ORO: 101365047(ADRB1)
EJU: 114223091(ADRB1)
ZCA: 113923428(ADRB1)
MLX: 118026567(ADRB1)
FCA: 493971(ADRB1)
PBG: 122493269(ADRB1)
PPAD: 109272931(ADRB1)
AJU: 113600301(ADRB1)
HHV: 120235331(ADRB1)
BTA: 281604(ADRB1)
BOM: 102270402(ADRB1)
BIU: 109553237(ADRB1)
BBUB: 102399704(ADRB1)
CHX: 102187558(ADRB1)
OAS: 443528(ADRB1)
ODA: 120873913(ADRB1)
CCAD: 122446563(ADRB1)
SSC: 397355(ADRB1)
CFR: 116666991(ADRB1)
CBAI: 105080806(ADRB1)
CDK: 105104750(ADRB1)
VPC: 116282527(ADRB1)
BACU: 103003267(ADRB1)
LVE: 103082012(ADRB1)
OOR: 101286166(ADRB1)
DLE: 111172295(ADRB1)
PCAD: 112064233(ADRB1)
PSIU: 116741698(ADRB1)
ECB: 100146832(ADRB1)
EAI: 123278100(ADRB1)
MYB: 102258046(ADRB1)
MMYO: 118669728(ADRB1)
MNA: 107536422(ADRB1)
PKL: 118719031(ADRB1)
HAI: 109392029(ADRB1)
DRO: 112300171(ADRB1)
SHON: 118999398(ADRB1)
AJM: 119040081(ADRB1)
PDIC: 114495957(ADRB1)
PHAS: 123829013(ADRB1)
MMF: 118632329(ADRB1)
RFQ: 117035752(ADRB1)
PALE: 102880796(ADRB1)
PGIG: 120609071(ADRB1)
PVP: 105291472(ADRB1)
RAY: 107511714(ADRB1)
MJV: 108384355(ADRB1)
TOD: 119234190(ADRB1)
SARA: 101558256(ADRB1)
LAV: 100654973(ADRB1)
TMU: 101347074
DNM: 101443500(ADRB1)
MDO: 100027410(ADRB1)
GAS: 123236281(ADRB1)
SHR: 116421895(ADRB1)
PCW: 110209527(ADRB1)
OAA: 100082919(ADRB1)
GGA: 101750705(ADRB1)
PCOC: 116231610(ADRB1)
MGP: 100303680(ADRB1)
CJO: 107316142(ADRB1)
NMEL: 110400444(ADRB1)
APLA: 101790405(ADRB1)
ACYG: 106031933(ADRB1)
AFUL: 116491490(ADRB1)
TGU: 100221186(ADRB3) 100221823(ADRB1)
LSR: 110468269(ADRB1)
SCAN: 103814126(ADRB1)
PMOA: 120502000(ADRB1)
OTC: 121341696(ADRB1)
PRUF: 121350186(ADRB1)
GFR: 102034437(ADRB1)
FAB: 101805929(ADRB1)
PHI: 102113245(ADRB1)
PMAJ: 107207049(ADRB1)
CCAE: 111930959(ADRB1)
CCW: 120410234(ADRB1)
CBRC: 103616294(ADRB1)
ETL: 114066977(ADRB1)
ZAB: 102061192(ADRB1)
FPG: 101917348(ADRB1)
FCH: 102052904(ADRB1)
CLV: 102087468(ADRB1)
EGZ: 104123630(ADRB1)
NNI: 104022377(ADRB1)
PLET: 104621128(ADRB1)
ACUN: 113481792(ADRB1)
TALA: 116960628(ADRB1)
PADL: 103918669(ADRB1)
ACHC: 115348366(ADRB1)
CMAC: 104486763
LDI: 104354936(ADRB1)
MNB: 103778596(ADRB1)
OHA: 104329509(ADRB1)
AAM: 106489475(ADRB1)
AROW: 112967933(ADRB1)
NPD: 112957142(ADRB1)
DNE: 112980955(ADRB1)
ASN: 102368318(ADRB1)
AMJ: 102574660(ADRB1)
CPOO: 109324345(ADRB1)
GGN: 109287633(ADRB1)
PSS: 102447221(ADRB1)
CMY: 102930847(ADRB1)
CPIC: 101935916(ADRB1)
TST: 117880854(ADRB1)
CABI: 116821746(ADRB1)
MRV: 120408953(ADRB1)
ACS: 100563228(adrb1)
PVT: 110071978(ADRB1)
SUND: 121927354(ADRB1)
PBI: 103066230(ADRB1)
PMUR: 107287322(ADRB1)
TSR: 106545862(ADRB1)
PGUT: 117678722(ADRB1)
VKO: 123027937(ADRB1)
PMUA: 114597471(ADRB1)
ZVI: 118093408(ADRB1)
GJA: 107122433(ADRB1)
STOW: 125438569(ADRB1)
XTR: 116412276
NPR: 108802079(ADRB1)
RTEM: 120946826(ADRB1)
BBUF: 121005104(ADRB1)
BGAR: 122941104(ADRB1)
DRE: 557194(adrb1)
SRX: 107755541
PPRM: 120474591(adrb1)
MAMB: 125255369(adrb1)
IPU: 108273437(adrb1)
PHYP: 113527186(adrb1)
SMEO: 124388447(adrb1)
TFD: 113638958(adrb1)
AMEX: 103043371(adrb1)
EEE: 113586622(adrb1)
TRU: 101068216(adrb1)
LCO: 104927885(adrb1)
CGOB: 115024347(adrb1)
ELY: 117246910(adrb1)
EFO: 125881205(adrb1)
PLEP: 121958919(adrb1)
SLUC: 116061397(adrb1)
ECRA: 117937180(adrb1)
PFLV: 114548388(adrb1)
GAT: 120819287(adrb1)
PPUG: 119212437(adrb1)
MSAM: 119916614(adrb1)
CUD: 121528452(adrb1)
ALAT: 119010163(adrb1)
MZE: 101474916(adrb1)
ONL: 100710833(adrb1)
OAU: 116329853(adrb1)
OLA: 101156611(adrb1)
OML: 112154216(adrb1)
XMA: 102226151(adrb1)
XCO: 114152261(adrb1)
XHE: 116726735(adrb1)
PRET: 103481286(adrb1)
PFOR: 103153377(adrb1)
PLAI: 106961051(adrb1)
PMEI: 106907511(adrb1)
GAF: 122823102(adrb1)
CVG: 107094714(adrb1)
CTUL: 119780495(adrb1)
GMU: 124875463(adrb1)
NFU: 107387883(adrb1)
KMR: 108247041(adrb1)
ALIM: 106516953(adrb1)
NWH: 119423646(adrb1)
AOCE: 111567295(adrb1)
MCEP: 125022000(adrb1)
CSEM: 103381516(adrb1)
POV: 109626653(adrb1)
SSEN: 122759026(adrb1)
HHIP: 117753159(adrb1)
HSP: 118100373(adrb1)
LCF: 108898720(adrb1)
SDU: 111219546(adrb1)
SLAL: 111669641(adrb1)
XGL: 120793936(adrb1)
HCQ: 109523917(adrb1)
BPEC: 110154323(adrb1)
MALB: 109963035(adrb1)
BSPL: 114845577(adrb1)
ELS: 105031082(adrb1)
SFM: 114910243(adrb1)
PKI: 111836057(adrb1)
AANG: 118219838(adrb1)
LOC: 102691081(adrb1)
ARUT: 117415298 117418120(adrb1)
LCM: 102359969(ADRB1)
CMK: 103186583(adrb1) 103190260
RTP: 109923571
BFO: 118413814
BBEL: 109462530
SKO: 102808166
BVK: 117237065
FAS: 105273260
DAM: 107040472
PXU: 106117456
PVM: 113825549
PCHN: 125036072
PTRU: 123517432
PPOI: 119090140
RSAN: 119401489
SDM: 118189487
GAE: 121381089
CRG: 105318459
AMIL: 114974417
 » show all
Reference
PMID:2825170
  Authors
Frielle T, Collins S, Daniel KW, Caron MG, Lefkowitz RJ, Kobilka BK
  Title
Cloning of the cDNA for the human beta 1-adrenergic receptor.
  Journal
Proc Natl Acad Sci U S A 84:7920-4 (1987)
DOI:10.1073/pnas.84.22.7920
  Sequence
[hsa:153]
Reference
  Authors
Pak Y, Pham N, Rotin D
  Title
Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation.
  Journal
Mol Cell Biol 22:7942-52 (2002)
DOI:10.1128/MCB.22.22.7942-7952.2002
  Sequence
[hsa:153]

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