KEGG ORTHOLOGY: K04147

ORTHOLOGY: K04147

Entry

K04147                      KO

Symbol

DRD4

Name

dopamine receptor D4

Pathway

map04080

Neuroactive ligand-receptor interaction

map04728

Dopaminergic synapse

Disease

H01450

Obsessive-compulsive disorder

H01671

Neurosis

H01895

Attention deficit hyperactivity disorder (ADHD)

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04147  DRD4; dopamine receptor D4
09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    K04147  DRD4; dopamine receptor D4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04147  DRD4; dopamine receptor D4
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Dopamine
    K04147  DRD4; dopamine receptor D4

Other DBs

GO:

0001591

Genes

HSA:	1815(DRD4)

PTR:	449578(DRD4)

PPS:	100975028(DRD4)

PON:	100462264(DRD4)

NLE:	100605969(DRD4)

HMH:	116466583(DRD4)

MCC:	699697(DRD4)

MCF:	102129091(DRD4)

MTHB:

126935840

MNI:	105494142(DRD4)

CSAB:

103231255(DRD4)

CATY:

105577204(DRD4)

PANU:

101006821(DRD4)

TGE:	112606858(DRD4)

RRO:	104656265(DRD4)

RBB:	108519717(DRD4)

TFN:	117079844(DRD4)

PTEH:

111533362(DRD4)

CANG:

105503278(DRD4)

CJC:	100410254(DRD4)

CIMI:

108288782(DRD4)

CSYR:

103252076(DRD4)

MMUR:

105874043(DRD4)

LCAT:

123641926(DRD4)

PCOQ:

105816504(DRD4)

OGA:	100942161(DRD4)

MMU:	13491(Drd4)

MCAL:

110299106(Drd4)

MPAH:

110336331(Drd4)

RNO:	25432(Drd4)

MCOC:

116100971(Drd4)

ANU:	117721041(Drd4)

MUN:	110553893(Drd4)

CGE:	100751093(Drd4)

MAUA:

101837477(Drd4)

PROB:

127227737(Drd4)

PLEU:

114695121(Drd4)

MORG:

121458134(Drd4)

MFOT:

126498200

AAMP:

119805682(Drd4)

NGI:	103751110(Drd4)

HGL:	101708437(Drd4)

CPOC:

100733356(Drd4)

CCAN:

109698036(Drd4)

DSP:	122102583(Drd4)

NCAR:

124960292

CFA:	119864199(DRD4)

CLUD:

112663528(DRD4)

VVP:	112914608(DRD4)

VLG:	121472190(DRD4)

AML:	105242158(DRD4)

UAH:	113248798(DRD4)

UAR:	123775549(DRD4)

ELK:

111149948

LLV:

125078588

MPUF:

106004514(DRD4)

NVS:	122914580(DRD4)

ORO:	101374603(DRD4)

EJU:	114201511(DRD4)

ZCA:	113915198(DRD4)

MLX:	118015661(DRD4)

NSU:	110582245(DRD4)

LWW:	102742999(DRD4)

FCA:	111556768(DRD4)

PYU:	121022811(DRD4)

PBG:	122484168(DRD4)

LRUF:

124527531

PPAD:

109259826(DRD4)

PUC:

125937386

AJU:	113596787(DRD4)

HHV:	120223421(DRD4)

BTA:	101906668(DRD4)

CHX:	108634223(DRD4)

OAS:	114110137(DRD4)

ODA:	120859780(DRD4)

CCAD:

122430586(DRD4)

SSC:	100512329(DRD4)

CFR:	102505709(DRD4)

CBAI:

105069987(DRD4)

CDK:	105105453(DRD4)

VPC:	102527132(DRD4)

BACU:

102998943(DRD4)

LVE:	103077762(DRD4)

OOR:	101276710(DRD4)

DLE:	111170290(DRD4)

PCAD:

102979303(DRD4)

PSIU:

116758686(DRD4)

ECB:	100147552(DRD4)

EAI:	123277790(DRD4)

MMYO:

118649020(DRD4)

MNA:	107542323(DRD4)

PKL:	118717953(DRD4)

HAI:	109375622(DRD4)

SHON:

118982257(DRD4)

AJM:	119062182(DRD4)

PDIC:

114499190(DRD4)

PHAS:

123807355(DRD4)

MMF:	118643168(DRD4)

RFQ:	117030456(DRD4)

PGIG:

120584668(DRD4)

RAY:	107507163(DRD4)

SARA:

101545829(DRD4)

LAV:	100655981(DRD4)

TMU:

101352591

ETF:	101648333(DRD4)

MDO:	100618204(DRD4)

SHR:	116420079(DRD4)

AFZ:

127541738

PCW:	110202979(DRD4)

OAA:	114810299(DRD4)

GGA:	423016(DRD4)

PCOC:

116237805(DRD4)

MGP:	100546496(DRD4)

CJO:	107314165(DRD4)

NMEL:

110401919(DRD4)

APLA:

101797742(DRD4)

ACYG:

106047027(DRD4)

AFUL:

116490135(DRD4)

TGU:	100228686(DRD4)

LSR:	110467571(DRD4)

SCAN:

103822310(DRD4)

PMOA:

120500962(DRD4)

OTC:	121337724(DRD4)

PRUF:

121357309(DRD4)

GFR:	102034185(DRD4)

FAB:	101816830(DRD4)

PHI:	102106131(DRD4)

PMAJ:

107205240(DRD4)

CCAE:

111930366(DRD4)

CCW:	120410159(DRD4)

CBRC:

103613051(DRD4)

ETL:	114067952(DRD4)

ZAB:	102066929(DRD4)

ACHL:

103809898(DRD4)

SVG:	106854726(DRD4)

FPG:	101923143(DRD4)

FCH:	102047285(DRD4)

CLV:	102096088(DRD4)

EGZ:	104131370(DRD4)

NNI:	104020528(DRD4)

PLET:

104616514(DRD4)

PCRI:

104037332(DRD4)

ACUN:

113481035(DRD4)

TALA:

104364574(DRD4)

PADL:

103925149(DRD4)

AFOR:

103902622(DRD4)

ACHC:

115352022(DRD4)

HALD:

104313536(DRD4)

HLE:	104829829(DRD4)

AGEN:

126047521

GCL:

127016976

CCRI:

104166681(DRD4)

CMAC:

104483889(DRD4)

MUI:	104546493(DRD4)

FGA:	104070893(DRD4)

GSTE:

104261022(DRD4)

LDI:	104346722(DRD4)

OHA:	104333302(DRD4)

NNT:	104412238(DRD4)

SHAB:

115607020(DRD4)

DPUB:

104299769(DRD4)

PGUU:

104468117(DRD4)

CPEA:

104385140(DRD4)

AVIT:

104272268(DRD4)

CVF:	104292995(DRD4)

CUCA:

104064429(DRD4)

TEO:	104379034(DRD4)

AAM:	106486729(DRD4)

AROW:

112969684(DRD4)

NPD:	112952065(DRD4)

TGT:	104580069(DRD4)

DNE:	112989506(DRD4)

SCAM:

104141485(DRD4)

ASN:	102382464(DRD4)

AMJ:	102563488(DRD4)

CPOO:

109318210(DRD4)

GGN:	109299217(DRD4)

PSS:	102459870(DRD4)

CMY:	102929688(DRD4)

CPIC:

101932676(DRD4)

TST:	117876638(DRD4)

CABI:

116838806(DRD4)

MRV:	120403000(DRD4)

ACS:	100565088(drd4)

PVT:	110074195(DRD4)

SUND:

121916972(DRD4)

PBI:	103051517(DRD4)

PMUR:

107283884(DRD4)

CTIG:

120298379(DRD4)

TSR:	106553964(DRD4)

PGUT:

117665186(DRD4)

VKO:	123021364(DRD4)

PMUA:

114599668(DRD4)

ZVI:	118089409(DRD4)

GJA:	107112901(DRD4)

STOW:

125427230(DRD4)

XLA:	108713876(drd4.L) 108715168(drd4.S)

XTR:	100486482(drd4)

NPR:	108786698(DRD4)

RTEM:

120917373(DRD4)

BBUF:

120980632(DRD4)

BGAR:

122921042(DRD4)

DRE:	503564(drd4a) 503565(drd4b) 503566(drd4-rs)

SRX:	107712616 107726856 107730172 107732971 107738833 107754372

SANH:

107655149 107663015 107674856 107686879 107694151 107699035 107699039

SGH:	107551439 107557292 107561186 107561434 107591318 107600352

CCAR:

109073213 109078485 109087161 109091546 109094269

CAUA:

113042899 113043031 113048621 113062541 113085976 113105314

CGIB:

127947342 127956300 127961115 127974354 128014175 128016297

PPRM:

120476541(drd4-rs) 120492597(drd4b)

MAMB:

125245979(drd4-rs) 125247823(drd4a) 125265821(drd4b)

CIDE:

127507668 127511435 127516671

MASI:

127410268 127435386 127436046 127436768 127437270 127442998

IPU:	108270559(drd4b) 108274555(drd4a)

PHYP:

113529991(drd4) 113536780

SMEO:

124391731(drd4b) 124391919(drd4a)

TFD:	113646739(drd4b) 113653925(drd4a)

AMEX:

103025686 103032612(drd4) 103044336

EEE:	113578778 113579982 113584503

TRU:	101074860(drd4) 101078250

TNG:	GSTEN00012495G001 GSTEN00016052G001

LCO:	104935131 104938444 109138022

NCC:	104954599 104966378(drd4)

CGOB:

115028220

ELY:	117249428(drd4-rs) 117250345 117252208(drd4b) 117262030(drd4a)

EFO:	125881073(drd4b) 125882734(drd4-rs) 125886752(drd4a)

PLEP:

121939267 121950530

SLUC:

116036286(drd4a) 116065893(drd4-rs) 116067285(drd4b)

ECRA:

117939695(drd4b) 117949746

ESP:	116687174 116693766

PFLV:

114555756 114560537

GAT:

120809248

PPUG:

119196202 119224960(drd4b)

MSAM:

119890599(drd4b) 119893082 119895521(drd4-rs)

CUD:	121505165(drd4-rs) 121513523(drd4b) 121515249

ALAT:

119017917(drd4b) 119024021(drd4a) 119032236(drd4-rs)

MZE:	101473075 101473958 101486227

ONL:	100693279 100704531 102079696

OAU:	116313811(drd4-rs) 116317509 116334296(drd4b)

OLA:	101164385 101173120 101173126

OML:	112139228(drd4a) 112141983(drd4b) 112157078(drd4-rs)

XMA:	102227358 102227899

XCO:	114142522 114161223

XHE:	116719273 116736570

PRET:

103459826(drd4) 103463031

PFOR:

103129965 103155219(drd4)

PLAI:

106935070 106949359(drd4)

PMEI:

106924555(drd4) 106931758

GAF:	122824605(drd4b) 122826481(drd4-rs)

CVG:	107082767 107092979

CTUL:

119778957(drd4-rs) 119780589(drd4b)

GMU:	124867248(drd4b) 124882737(drd4-rs)

NFU:	107382056 107396082(drd4)

KMR:	108229721(drd4-rs) 108249900(drd4a) 112449904(drd4b)

ALIM:

106513125 106530946(drd4)

NWH:	119415370(drd4a)

AOCE:

111567783 111575966 111582546

MCEP:

125005005(drd4b) 125015014

CSEM:

103378863(drd4) 103379532 103384452

POV:	109624109 109646117

SSEN:

122772392(drd4b) 122776235

HHIP:

117759157(drd4b) 117763555

HSP:	118109068(drd4a) 118109213(drd4b)

LCF:	108892411(drd4-rs) 108893793 108894166

SDU:	111223087 111235997 111238877

SLAL:

111656652 111665067(drd4) 111670436

XGL:	120792454(drd4b) 120792711 120801219(drd4-rs)

HCQ:	109514277 109522924(drd4)

SSCV:

125967089 125970305

BPEC:

110161856 110163789(drd4)

MALB:

109956462(drd4) 109967751 109971561

BSPL:

114851851(drd4b) 114857032

SASA:

106561126 106562687 106576100 106584511 106587966 106595330 106609138

STRU:

115166720 115180425 115192719 115197014 115198681 115203602

OTW:	112214397 112216807(drd4-rs) 112219080 112222030(drd4a) 112240898(drd4b)

OMY:	110490201(drd4-rs) 110492890 110500258 110521350(drd4a) 118944527 118964984(drd4b)

OGO:	123994706 124009896 124013629 124019856 124019884 124037602(drd4a)

ONE:	115106245 115133219 115134464 115144801(drd4)

SALP:

111950911 111951363 111962180 111971660

SNH:	120031782 120037911 120037912 120049067 120051793 120066589

CCLU:

121531297 121539962(drd4a) 121543713 121546287 121583049(drd4b)

ELS:	105007372 105020169 105028893

SFM:	108934547 108936381 108942227

PKI:	111833243 111840434 111859430

AANG:

118214763 118219065 118227217 118231183(drd4-rs)

LOC:	102686099(drd4) 102691939

PSPA:

121295035 121319048 121320262(drd4-rs) 121329492

ARUT:

117415356 117432453 117434428

PSEX:

120519700(drd4a) 120534122(drd4-rs)

LCM:	102349281(DRD4) 102352528

CMK:

103189088

RTP:	109928816(drd4) 109932153

CPLA:

122557749 122561503(drd4-rs)

BFO:

BBEL:

ACER:

MGEN:

MSEX:

BGT:

Reference

PMID:1840645

Authors

Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB, Civelli O

Title

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine.

Journal

Nature 350:610-4 (1991)
DOI:10.1038/350610a0

Sequence

[hsa:1815]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (3)   
Drug (21)   
   KEGG DRUG (21)   
Gene (646)   
   KEGG GENES (480)   
   KEGG MGENES (89)   
   RefGene (73)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (678)   

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