KEGG   ORTHOLOGY: K04603
Entry
K04603                      KO                                     
Symbol
GRM1
Name
metabotropic glutamate receptor 1
Pathway
map04020  Calcium signaling pathway
map04068  FoxO signaling pathway
map04072  Phospholipase D signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04540  Gap junction
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04730  Long-term depression
map04742  Taste transduction
map04915  Estrogen signaling pathway
map05017  Spinocerebellar ataxia
map05022  Pathways of neurodegeneration - multiple diseases
Disease
H00063  Spinocerebellar ataxia (SCA)
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
   04020 Calcium signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
   04072 Phospholipase D signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04603  GRM1; metabotropic glutamate receptor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04603  GRM1; metabotropic glutamate receptor 1
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
  09156 Nervous system
   04724 Glutamatergic synapse
    K04603  GRM1; metabotropic glutamate receptor 1
   04720 Long-term potentiation
    K04603  GRM1; metabotropic glutamate receptor 1
   04730 Long-term depression
    K04603  GRM1; metabotropic glutamate receptor 1
   04723 Retrograde endocannabinoid signaling
    K04603  GRM1; metabotropic glutamate receptor 1
  09157 Sensory system
   04742 Taste transduction
    K04603  GRM1; metabotropic glutamate receptor 1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K04603  GRM1; metabotropic glutamate receptor 1
   05022 Pathways of neurodegeneration - multiple diseases
    K04603  GRM1; metabotropic glutamate receptor 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04603  GRM1; metabotropic glutamate receptor 1
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04603  GRM1; metabotropic glutamate receptor 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04603  GRM1; metabotropic glutamate receptor 1
G protein-coupled receptors [BR:ko04030]
 Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   K04603  GRM1; metabotropic glutamate receptor 1
Other DBs
GO: 0001639
TC: 9.A.14.7.1
Genes
HSA: 2911(GRM1)
PTR: 463049(GRM1)
PPS: 100968079(GRM1)
GGO: 101150458(GRM1)
PON: 100451342(GRM1)
NLE: 100592587(GRM1)
MCC: 698736(GRM1)
MCF: 102145647(GRM1)
CSAB: 103240205(GRM1)
CATY: 105588798(GRM1)
PANU: 101005483(GRM1)
TGE: 112622646(GRM1)
TFN: 117097320(GRM1)
PTEH: 111528139(GRM1)
CJC: 100410312(GRM1)
SBQ: 101036619(GRM1)
CSYR: 103269071
MMUR: 105864337(GRM1)
LCAT: 123633346(GRM1)
OGA: 100959023(GRM1)
MMU: 14816(Grm1)
MCAL: 110303088(Grm1)
MPAH: 110338039(Grm1)
RNO: 24414(Grm1)
MCOC: 116097763(Grm1)
CGE: 100751598(Grm1)
MAUA: 101831018(Grm1)
PLEU: 114686464(Grm1)
MORG: 121466446(Grm1)
AAMP: 119821203(Grm1)
NGI: 103737030(Grm1)
HGL: 101712477(Grm1)
CPOC: 100730891(Grm1)
DORD: 105993642(Grm1)
DSP: 122125197(Grm1)
NCAR: 124989681
OCU: 100356201(GRM1)
OPI: 101516509(GRM1)
TUP: 102479064(GRM1)
CFA: 484024(GRM1)
VVP: 112919501(GRM1)
VLG: 121479810(GRM1)
AML: 100479929(GRM1)
UAH: 113259527(GRM1)
UAR: 123797395(GRM1)
ELK: 111147676
LLV: 125103220
MPUF: 101686929(GRM1)
EJU: 114209321(GRM1)
ZCA: 113928053(GRM1)
MLX: 118001000(GRM1)
FCA: 101094104(GRM1)
PYU: 121013347(GRM1)
PBG: 122490065(GRM1)
PTG: 102961964(GRM1)
PPAD: 109252510(GRM1)
AJU: 106965803(GRM1)
HHV: 120231041(GRM1)
BTA: 540485(GRM1)
BOM: 102280395(GRM1)
BIU: 109563668(GRM1)
BBUB: 102414394(GRM1)
OAS: 443101(GRM1)
ODA: 120862584(GRM1)
CCAD: 122434178(GRM1)
SSC: 100625610(GRM1)
CFR: 102523079(GRM1)
CBAI: 105077300(GRM1)
CDK: 105092074(GRM1)
VPC: 102535537(GRM1)
LVE: 103085587(GRM1)
OOR: 101286756(GRM1)
DLE: 111166689(GRM1)
PCAD: 102978027(GRM1)
PSIU: 116763496(GRM1)
ECB: 100060603(GRM1)
EPZ: 103564725(GRM1)
EAI: 106837226(GRM1)
MMYO: 118660637(GRM1)
MLF: 102428336(GRM1)
PKL: 118705702(GRM1)
HAI: 109380898(GRM1)
DRO: 112297397(GRM1)
AJM: 119049056(GRM1)
PDIC: 114495128(GRM1)
PHAS: 123821691(GRM1)
MMF: 118621105(GRM1)
RFQ: 117020443(GRM1)
PALE: 102878912(GRM1)
PGIG: 120589402(GRM1)
PVP: 105289441(GRM1)
RAY: 107518526(GRM1)
TOD: 119252954(GRM1)
SARA: 101542044(GRM1)
TMU: 101357087
DNM: 101447287
MDO: 100026724(GRM1)
GAS: 123246629(GRM1)
SHR: 100919608(GRM1)
PCW: 110208519(GRM1)
OAA: 100075372(GRM1)
GGA: 421614(GRM1)
PCOC: 116241737(GRM1)
MGP: 100540165(GRM1)
CJO: 107311576(GRM1)
APLA: 101803914(GRM1)
ACYG: 106034294(GRM1)
AFUL: 116487901(GRM1)
TGU: 751999(GRM1)
LSR: 110468842(GRM1)
SCAN: 103818453(GRM1)
PMOA: 120501378(GRM1)
OTC: 121346039(GRM1)
PRUF: 121354867(GRM1)
GFR: 102038278(GRM1)
FAB: 101807135(GRM1)
PHI: 102107527(GRM1)
PMAJ: 107202384(GRM1)
CCAE: 111927059(GRM1)
CCW: 104689210(GRM1)
ZAB: 102070841(GRM1)
FPG: 101920400(GRM1)
CLV: 102091439(GRM1)
EGZ: 104133563(GRM1)
NNI: 104013781(GRM1)
PLET: 104623282
TALA: 104361564(GRM1)
PADL: 103918143(GRM1)
ACHC: 115345049(GRM1)
AAM: 106486778(GRM1)
AROW: 112974150(GRM1)
NPD: 112951956(GRM1)
DNE: 112983279(GRM1)
ASN: 102378290(GRM1)
AMJ: 102563002(GRM1)
CPOO: 109319121(GRM1)
GGN: 109304791(GRM1)
PSS: 102460135(GRM1)
CMY: 102932638(GRM1)
CPIC: 101940955(GRM1)
TST: 117874861(GRM1)
CABI: 116833187(GRM1)
MRV: 120402034(GRM1)
ACS: 100564433(grm1)
PVT: 110088369(GRM1)
SUND: 121919479(GRM1)
TSR: 106543622(GRM1)
PGUT: 117666344(GRM1)
VKO: 123032748(GRM1)
PMUA: 114594222(GRM1)
ZVI: 118082832(GRM1)
STOW: 125437609
XTR: 100495945(grm1)
NPR: 108787741(GRM1)
RTEM: 120937555(GRM1)
BBUF: 120999276(GRM1)
BGAR: 122935464(GRM1)
DRE: 100150246(grm1b) 555576(grm1a)
CCAR: 109108722
PPRM: 120480202(grm1b) 120494051(grm1a)
MAMB: 125268361(grm1b) 125278093(grm1a)
IPU: 108270069(grm1b) 108279026(grm1a)
SMEO: 124390628(grm1b) 124401793(grm1a)
TFD: 113643380(grm1a) 113659571(grm1b)
TRU: 101065368(grm1) 101071408
LCO: 104929400 104934310(grm1)
CGOB: 115004925 115028830(grm1)
ELY: 117267639(grm1b) 117271197(grm1a)
PLEP: 121954147(grm1b) 121955656(grm1a)
SLUC: 116057666(grm1b) 116066169(grm1a)
ECRA: 117935939(grm1b) 117961555(grm1a)
PFLV: 114546747 114572847(grm1)
GAT: 120807652(grm1a) 120833264(grm1b)
PPUG: 119195374(grm1a) 119227715(grm1b)
MSAM: 119908408(grm1a) 119910801
CUD: 121521017(grm1a) 121525845
ALAT: 119012531(grm1a) 119034234(grm1b)
MZE: 101467938 101483242(grm1)
ONL: 100697502 100701745(grm1)
OAU: 116310668(grm1a) 116318116(grm1b)
OLA: 101165118(grm1) 101170976
OML: 112142945(grm1b) 112157966(grm1a)
XMA: 102224833(grm1) 102226132
XCO: 114134732 114158865(grm1)
XHE: 116709324 116734017(grm1)
PRET: 103457526(grm1) 103458356
GAF: 122825690(grm1a) 122846438(grm1b)
CVG: 107086032(grm1) 107091581
CTUL: 119792758(grm1b) 119795948(grm1a)
GMU: 124855863(grm1b) 124882406(grm1a)
NFU: 107377567(grm1) 107391977
KMR: 108239081(grm1b) 108240124(grm1a)
ALIM: 106519782(grm1)
NWH: 119418222(grm1a) 119427470(grm1b)
AOCE: 111572587(grm1) 111578565
CSEM: 103380242 103381085(grm1)
POV: 109636085(grm1)
SSEN: 122782935 122784448(grm1a)
HHIP: 117756137(grm1b) 117758227(grm1a)
HSP: 118099176(grm1a) 118116980(grm1b)
SDU: 111225349 111240111(grm1)
SLAL: 111655604(grm1) 111665818
XGL: 120789204(grm1a) 120795478(grm1b)
HCQ: 109527746(grm1)
BPEC: 110155964(grm1)
MALB: 109954042(grm1)
BSPL: 114848636(grm1b) 114849174(grm1a)
SFM: 108923354
PKI: 111857957
AANG: 118228541(grm1b) 118229128(grm1a)
LOC: 102687262(grm1)
LCM: 102359097(GRM1)
CMK: 103179290(grm1b)
BFO: 118422754
BBEL: 109464724
CPII: 120424103
NVI: 100118400
TPRE: 106659666
FAS: 105263454
DAM: 107042600
CCIN: 107271356
PPYR: 116176120
SLIU: 111362599
NLU: 111053765
CSEC: 111864910
HAME: 121854265
DSV: 119461421
RMP: 119174367
HRF: 124116628
MMER: 123552410
OSN: 118762639
XEN: 124433505
HMG: 100206629
 » show all
Reference
PMID:1847995
  Authors
Masu M, Tanabe Y, Tsuchida K, Shigemoto R, Nakanishi S
  Title
Sequence and expression of a metabotropic glutamate receptor.
  Journal
Nature 349:760-5 (1991)
DOI:10.1038/349760a0
  Sequence
[rno:24414]

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