KEGG   ORTHOLOGY: K04913
Entry
K04913                      KO                                     

Name
KCNK2, K2P2.1
Definition
potassium channel subfamily K member 2
Pathway
ko04927  Cortisol synthesis and secretion
ko04934  Cushing syndrome
ko04971  Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    K04913  KCNK2, K2P2.1; potassium channel subfamily K member 2
  09154 Digestive system
   04971 Gastric acid secretion
    K04913  KCNK2, K2P2.1; potassium channel subfamily K member 2
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04913  KCNK2, K2P2.1; potassium channel subfamily K member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04913  KCNK2, K2P2.1; potassium channel subfamily K member 2
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, two-pore domain (K2P)
   K04913  KCNK2, K2P2.1; potassium channel subfamily K member 2
Other DBs
GO: 0022841
TC: 1.A.1.9.1
Genes
HSA: 3776(KCNK2)
PTR: 457734(KCNK2)
PPS: 100991720(KCNK2)
GGO: 101149331(KCNK2)
PON: 100435329(KCNK2)
NLE: 100601855(KCNK2)
MCC: 708705(KCNK2)
MCF: 102146456(KCNK2)
CSAB: 103230096(KCNK2)
RRO: 104657055(KCNK2)
RBB: 108528238(KCNK2)
CJC: 100400002(KCNK2)
SBQ: 101048117(KCNK2)
MMU: 16526(Kcnk2)
MCAL: 110292906(Kcnk2)
MPAH: 110321229(Kcnk2)
RNO: 170899(Kcnk2)
MUN: 110553409(Kcnk2)
CGE: 100751502(Kcnk2)
NGI: 103727069(Kcnk2)
HGL: 101722094(Kcnk2)
CCAN: 109700240(Kcnk2)
OCU: 100356478(KCNK2)
TUP: 102488856(KCNK2)
CFA: 490295(KCNK2)
VVP: 112921786(KCNK2)
AML: 100481291(KCNK2)
UMR: 103672450(KCNK2)
UAH: 113262981(KCNK2)
ORO: 101374381(KCNK2)
ELK: 111150823
FCA: 101096695(KCNK2)
PTG: 102968820(KCNK2)
PPAD: 109254391(KCNK2)
AJU: 106966794(KCNK2)
BTA: 282590(KCNK2)
BOM: 102271922(KCNK2)
BIU: 109570750(KCNK2)
BBUB: 102413225(KCNK2)
CHX: 102179222(KCNK2)
OAS: 101111729(KCNK2)
SSC: 100627197(KCNK2)
CFR: 102509102(KCNK2)
CDK: 105099341(KCNK2)
BACU: 103013336(KCNK2)
LVE: 103089238(KCNK2)
OOR: 101270799(KCNK2)
DLE: 111184609(KCNK2)
PCAD: 102981407(KCNK2)
ECB: 100050114(KCNK2)
EPZ: 103559377(KCNK2)
EAI: 106846819(KCNK2)
MYB: 102263619
MYD: 102773670(KCNK2)
MNA: 107546296(KCNK2)
HAI: 109379086(KCNK2)
DRO: 112296671(KCNK2)
PALE: 102885724(KCNK2)
RAY: 107521645(KCNK2)
MJV: 108391322(KCNK2)
LAV: 100654542(KCNK2)
TMU: 101349413
MDO: 100023531(KCNK2)
SHR: 100935232(KCNK2)
PCW: 110222680(KCNK2)
OAA: 100079421(KCNK2)
GGA: 770954(KCNK2)
MGP: 100538823(KCNK2)
CJO: 107311088(KCNK2)
NMEL: 110395509(KCNK2)
APLA: 101802542(KCNK2)
ACYG: 106031574(KCNK2)
TGU: 100220097(KCNK2)
LSR: 110479967(KCNK2)
SCAN: 103821508(KCNK2)
GFR: 102039165(KCNK2)
FAB: 101815844(KCNK2)
PHI: 102101096(KCNK2)
PMAJ: 107202578(KCNK2)
CCAE: 111926195(KCNK2)
CCW: 104685631(KCNK2)
ETL: 114060903(KCNK2)
FPG: 101923937(KCNK2)
FCH: 102055556(KCNK2)
CLV: 102086497(KCNK2)
EGZ: 104132858(KCNK2)
NNI: 104019660(KCNK2)
ACUN: 113478704(KCNK2)
PADL: 103922112(KCNK2)
AAM: 106490378(KCNK2)
ASN: 102385689(KCNK2)
AMJ: 102576820(KCNK2)
PSS: 102452042(KCNK2)
CMY: 102947248(KCNK2)
CPIC: 101947567(KCNK2)
ACS: 100558061(kcnk2)
PVT: 110087179(KCNK2)
PBI: 103067710(KCNK2)
PMUR: 107289293(KCNK2)
TSR: 106555457(KCNK2)
PMUA: 114594671(KCNK2)
GJA: 107125653(KCNK2)
XLA: 108716457(kcnk2.L) 108717710(kcnk2.S)
XTR: 100495685(kcnk2)
NPR: 108784775(KCNK2)
DRE: 559728(kcnk2a) 568565(kcnk2b)
IPU: 108261241(kcnk2)
PHYP: 113528844(kcnk2)
AMEX: 103023432
EEE: 113591913
TRU: 101071825(kcnk2) 101075749
NCC: 104947338(kcnk2) 104966753
MZE: 101474522 101479664(kcnk2)
ONL: 100699231 100708445(kcnk2)
OLA: 101165275(kcnk2) 101168108
XMA: 102232358 102238204(kcnk2)
XCO: 114142707 114158719(kcnk2)
PRET: 103457649(kcnk2) 103462837
CVG: 107083347(kcnk2) 107092146
NFU: 107377589(kcnk2) 107381183
KMR: 108237338(kcnk2a) 108240075
ALIM: 106513130 106516937(kcnk2)
AOCE: 111568229(kcnk2) 111570296
CSEM: 103380829(kcnk2)
POV: 109636214(kcnk2) 109636747
LCF: 108877004 108895647(kcnk2)
SDU: 111221101 111239238(kcnk2)
HCQ: 109516756(kcnk2) 109528781
BPEC: 110154405(kcnk2) 110172983
MALB: 109954288(kcnk2) 109954548
SASA: 106603213(kcnk10) 106607929(kcnk2) 106611358
ELS: 105015423(kcnk2)
SFM: 108924047(kcnk2)
LCM: 102353730(KCNK2)
CMK: 103186169(kcnk2)
RTP: 109919499(kcnk2)
CIN: 100179668
SPU: 575019
 » show all
Reference
  Authors
Bockenhauer D, Zilberberg N, Goldstein SA
  Title
KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel.
  Journal
Nat Neurosci 4:486-91 (2001)
DOI:10.1038/87434
  Sequence
[hsa:3776]
Reference
  Authors
Meadows HJ, Benham CD, Cairns W, Gloger I, Jennings C, Medhurst AD, Murdock P, Chapman CG
  Title
Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel.
  Journal
Pflugers Arch 439:714-22 (2000)
DOI:10.1007/s004249900235
  Sequence
[hsa:3776]

KEGG   ORTHOLOGY: K04920
Entry
K04920                      KO                                     

Name
KCNK10, K2P10.1
Definition
potassium channel subfamily K member 10
Pathway
ko04971  Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    K04920  KCNK10, K2P10.1; potassium channel subfamily K member 10
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04920  KCNK10, K2P10.1; potassium channel subfamily K member 10
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04920  KCNK10, K2P10.1; potassium channel subfamily K member 10
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04920  KCNK10, K2P10.1; potassium channel subfamily K member 10
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, two-pore domain (K2P)
   K04920  KCNK10, K2P10.1; potassium channel subfamily K member 10
Other DBs
GO: 0022841
TC: 1.A.1.9.4
Genes
HSA: 54207(KCNK10)
PTR: 736753(KCNK10)
PPS: 100988462(KCNK10)
GGO: 101139654(KCNK10)
PON: 100459817(KCNK10)
NLE: 100588245(KCNK10)
MCC: 694669(KCNK10)
MCF: 102146600(KCNK10)
CSAB: 103229492(KCNK10)
RRO: 104678549(KCNK10)
RBB: 108522796(KCNK10)
CJC: 100413228(KCNK10)
SBQ: 101045018(KCNK10)
MMU: 72258(Kcnk10)
MCAL: 110307089(Kcnk10)
MPAH: 110324244(Kcnk10)
RNO: 65272(Kcnk10)
MUN: 110551254(Kcnk10)
CGE: 100750735(Kcnk10)
NGI: 103742713(Kcnk10)
HGL: 101721172(Kcnk10)
OCU: 100009503(KCNK10)
TUP: 102482882(KCNK10)
CFA: 490822(KCNK10)
VVP: 112930189(KCNK10)
AML: 100472604(KCNK10)
UMR: 103673934(KCNK10)
UAH: 113267387(KCNK10)
ORO: 101364079(KCNK10)
ELK: 111148667
FCA: 101091456(KCNK10)
PTG: 102954342(KCNK10)
PPAD: 109274422(KCNK10)
AJU: 106989904(KCNK10)
BTA: 525109(KCNK10)
BOM: 102283111(KCNK10)
BIU: 109565406(KCNK10)
BBUB: 102413916(KCNK10)
CHX: 102188322(KCNK10)
OAS: 101113681(KCNK10)
SSC: 100155276(KCNK10)
CFR: 102521934(KCNK10)
CDK: 105096758(KCNK10)
BACU: 103011778(KCNK10)
LVE: 103077112(KCNK10)
OOR: 101279751(KCNK10)
DLE: 111176182(KCNK10)
PCAD: 102991366(KCNK10)
ECB: 100061881(KCNK10)
EPZ: 103551796(KCNK10)
EAI: 106834297(KCNK10)
MYB: 102257725(KCNK10)
MYD: 102761158(KCNK10)
MNA: 107534866(KCNK10)
HAI: 109382644(KCNK10)
DRO: 112311614(KCNK10)
PALE: 102881872(KCNK10)
RAY: 107499536(KCNK10)
MJV: 108394450(KCNK10)
LAV: 100660189(KCNK10)
TMU: 101355262
MDO: 100019320(KCNK10)
SHR: 100914508(KCNK10)
PCW: 110217773(KCNK10)
OAA: 100089254(KCNK10)
GGA: 428902(KCNK10)
MGP: 100549775(KCNK10)
CJO: 107315261(KCNK10)
NMEL: 110402000(KCNK10)
APLA: 101801403(KCNK10)
ACYG: 106036924(KCNK10)
TGU: 100219150(KCNK10)
LSR: 110476195(KCNK10)
SCAN: 103826487(KCNK10)
GFR: 102041549(KCNK10)
FAB: 101810472(KCNK10)
PHI: 102113487(KCNK10)
PMAJ: 107205259(KCNK10)
CCAE: 111929917(KCNK10)
CCW: 104685807(KCNK10)
ETL: 114069329(KCNK10)
FPG: 101924730(KCNK10)
FCH: 102049182(KCNK10)
CLV: 102097941(KCNK10)
EGZ: 104126304(KCNK10)
NNI: 104022224(KCNK10)
ACUN: 113480846(KCNK10)
PADL: 103912989(KCNK10)
AAM: 106483122(KCNK10)
ASN: 102384308(KCNK10)
AMJ: 102575089(KCNK10)
PSS: 102456560(KCNK10)
CMY: 102930922(KCNK10)
CPIC: 101953183(KCNK10)
ACS: 100564560(kcnk10)
PVT: 110069986(KCNK10)
PBI: 103059917(KCNK10)
PMUR: 107299920(KCNK10)
TSR: 106547136(KCNK10)
PMUA: 114591286(KCNK10)
GJA: 107123398(KCNK10)
XLA: 108699831(kcnk10.S) 446288(kcnk10.L)
XTR: 100497885(kcnk10)
NPR: 108792557(KCNK10)
DRE: 563228(kcnk10a) 565629(kcnk10b)
IPU: 108257634 108269658(kcnk10)
PHYP: 113524813 113538538(kcnk10)
AMEX: 103030192(kcnk10) 103032675
TRU: 101075883(kcnk10)
LCO: 104924150(kcnk10) 109139602
NCC: 104942342(kcnk10) 104965095
ONL: 100699239 100712091(kcnk10)
OLA: 101162012(kcnk10) 101171299
XMA: 102227894(kcnk10)
XCO: 114134720(kcnk10)
PRET: 103459964(kcnk10)
CVG: 107098748(kcnk10)
NFU: 107392183(kcnk10)
KMR: 108232717(kcnk10b)
ALIM: 106526358(kcnk10)
AOCE: 111573279(kcnk10) 111574115
LCF: 108875085(kcnk10) 108901748
SDU: 111225979(kcnk10) 111239764
BPEC: 110156585(kcnk10) 110163494
MALB: 109966561 109968008(kcnk10)
SFM: 108924038(kcnk10)
PKI: 111841751(kcnk10)
LCM: 102353926(KCNK10)
CMK: 103185364(kcnk10)
RTP: 109939131(kcnk10)
BFO: 118428199
CIN: 100183963
APLC: 110990177
PVM: 113818444
TUT: 107367398
DPTE: 113789326
CSCU: 111623342
PTEP: 107436952
LAK: 106181448
 » show all
Reference
  Authors
Huang D, Yu B
  Title
Recent advance and possible future in TREK-2: a two-pore potassium channel may involved in the process of NPP, brain ischemia and memory impairment.
  Journal
Med Hypotheses 70:618-24 (2008)
DOI:10.1016/j.mehy.2007.06.016
  Sequence
[hsa:54207]

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