KEGG   ORTHOLOGY: K04961
Entry
K04961                      KO                                     
Symbol
RYR1
Name
ryanodine receptor 1
Pathway
map04020  Calcium signaling pathway
map04371  Apelin signaling pathway
map04713  Circadian entrainment
map04730  Long-term depression
map04921  Oxytocin signaling pathway
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
Disease
H00699  Central core disease
H01310  Multi-minicore disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04961  RYR1; ryanodine receptor 1
   04020 Calcium signaling pathway
    K04961  RYR1; ryanodine receptor 1
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K04961  RYR1; ryanodine receptor 1
  09156 Nervous system
   04730 Long-term depression
    K04961  RYR1; ryanodine receptor 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04961  RYR1; ryanodine receptor 1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K04961  RYR1; ryanodine receptor 1
   05020 Prion disease
    K04961  RYR1; ryanodine receptor 1
   05022 Pathways of neurodegeneration - multiple diseases
    K04961  RYR1; ryanodine receptor 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04961  RYR1; ryanodine receptor 1
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04961  RYR1; ryanodine receptor 1
   04040 Ion channels
    K04961  RYR1; ryanodine receptor 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04961  RYR1; ryanodine receptor 1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04961  RYR1; ryanodine receptor 1
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ryanodine receptor
   K04961  RYR1; ryanodine receptor 1
Other DBs
GO: 0005219
TC: 1.A.3.1.2
Genes
HSA: 6261(RYR1)
PTR: 100612063(RYR1)
PPS: 100992272(RYR1)
GGO: 101143735(RYR1)
PON: 100447042(RYR1)
NLE: 100592793
MCC: 693612(RYR1)
MCF: 102129553(RYR1)
CSAB: 103234633(RYR1)
CATY: 105594519(RYR1)
PANU: 101026547
TGE: 112613556(RYR1)
RRO: 104679962(RYR1)
RBB: 108538989(RYR1)
TFN: 117092481(RYR1)
PTEH: 111554005(RYR1)
CJC: 100405957(RYR1)
SBQ: 101040405(RYR1)
MMUR: 105877018(RYR1)
LCAT: 123624371(RYR1)
OGA: 100962804(RYR1)
MMU: 20190(Ryr1)
MCAL: 110299024(Ryr1)
MPAH: 110330776(Ryr1)
RNO: 114207(Ryr1)
MCOC: 116101936(Ryr1)
MUN: 110552535(Ryr1)
CGE: 100766013(Ryr1)
MAUA: 101840708(Ryr1)
PLEU: 114684981(Ryr1)
MORG: 121449089(Ryr1)
AAMP: 119820756(Ryr1)
NGI: 103750787(Ryr1)
HGL: 101708954(Ryr1)
CPOC: 100727848(Ryr1)
CCAN: 109695821(Ryr1)
DORD: 105993062(Ryr1)
DSP: 122097395(Ryr1)
NCAR: 124966810
OCU: 100009540(RYR1)
OPI: 101521583(RYR1)
TUP: 102475336(RYR1)
CFA: 606491(RYR1)
VVP: 112928307(RYR1)
VLG: 121483797(RYR1)
AML: 100471044(RYR1)
UMR: 103661069(RYR1)
UAH: 113243259(RYR1)
UAR: 123784559(RYR1)
ELK: 111161376
LLV: 125089926
MPUF: 101672983(RYR1)
ORO: 101364655(RYR1)
EJU: 114198938(RYR1)
ZCA: 113935520(RYR1)
MLX: 118022771(RYR1)
FCA: 101094224(RYR1)
PYU: 121011339(RYR1)
PBG: 122494096(RYR1)
PTG: 102971670(RYR1)
PPAD: 109256597(RYR1)
AJU: 106980247(RYR1)
HHV: 120220611(RYR1)
BTA: 100139857(RYR1)
BOM: 102275567(RYR1)
BBUB: 102398635(RYR1)
CHX: 102179229(RYR1)
OAS: 101112591(RYR1)
ODA: 120873294(RYR1)
CCAD: 122420334(RYR1)
SSC: 396718(RYR1)
CFR: 102516436(RYR1)
CDK: 105096948(RYR1)
VPC: 102525492(RYR1)
BACU: 103007765(RYR1)
LVE: 103069357(RYR1)
OOR: 101283632(RYR1)
DLE: 111180892(RYR1)
PCAD: 102976725
PSIU: 116743441(RYR1)
ECB: 100034090(RYR1)
EPZ: 103541052(RYR1)
EAI: 106836101(RYR1)
MYB: 102253755(RYR1)
MYD: 102763591(RYR1)
MMYO: 118674213(RYR1)
MLF: 102437305(RYR1)
MNA: 107532181(RYR1)
PKL: 118702392(RYR1)
HAI: 109395341
DRO: 112319987(RYR1)
SHON: 118976360(RYR1)
AJM: 119046710(RYR1)
PDIC: 114510907(RYR1)
PHAS: 123823738(RYR1)
MMF: 118639622(RYR1)
RFQ: 117034373(RYR1)
PALE: 102891286(RYR1)
PGIG: 120596309(RYR1)
PVP: 105300232(RYR1) 105304450
RAY: 107520956(RYR1)
MJV: 108399498
TOD: 119250147(RYR1)
SARA: 101550906(RYR1)
LAV: 100655020(RYR1)
TMU: 101351543
DNM: 101431584
MDO: 100013232(RYR1)
GAS: 123240034(RYR1)
SHR: 100916717(RYR1)
PCW: 110202421(RYR1)
OAA: 100681936(RYR1)
GGA: 101748756(RYR1L1)
MGP: 100008574(RYR1)
LSR: 110481838
PMOA: 120505122
PHI: 102114265(RYR1)
CLV: 102094459
AROW: 112961560
ASN: 102379620(RYR1)
AMJ: 102563585(RYR1)
CMY: 102946217(RYR1)
CPIC: 101952293(RYR1)
TST: 117888922(RYR1)
MRV: 120388242(RYR1)
ACS: 100558429(ryr1)
PVT: 110075640(RYR1)
SUND: 121915128(RYR1)
PBI: 103063254(RYR1)
PMUR: 107293912(RYR1)
PGUT: 117677601
VKO: 123025844(RYR1)
PMUA: 114603221(RYR1)
ZVI: 118086895(RYR1)
GJA: 107117768
XLA: 108698642(ryr1.L) 108700581
XTR: 100495378(ryr1)
NPR: 108786654(RYR1)
RTEM: 120913406(RYR1)
BBUF: 121009321(RYR1)
BGAR: 122946356(RYR1)
DRE: 570245(ryr1b) 798565(ryr1a)
PPRM: 120482698(ryr1a) 120487887(ryr1b)
MAMB: 125254212(ryr1b) 125262225(ryr1a)
IPU: 108264731 108276801(ryr1a)
SMEO: 124393574(ryr1a) 124395450
TFD: 113650233(ryr1a) 113650773
AMEX: 103022324(ryr1) 103047751
NCC: 104963769 104967745(ryr1)
ELY: 117259471(ryr1b) 117267084
PLEP: 121943032(ryr1b) 121952273
SLUC: 116040031(ryr1b) 116064741(ryr1a)
ECRA: 117938068(ryr1b) 117955843
GAT: 120817717(ryr1b) 120822199
PPUG: 119215626 119216058(ryr1b)
MSAM: 119883493(ryr1b) 119895837
CUD: 121518712 121524386(ryr1b)
ALAT: 119030801 119034262(ryr1b)
OAU: 116336197 116336492(ryr1b)
OLA: 101160087(ryr1) 101167142
OML: 112141892 112149715(ryr1b)
PRET: 103475196(ryr1) 103475680
GAF: 122833037(ryr1b) 122844448
CTUL: 119778063 119785721(ryr1b)
GMU: 124876344 124883896(ryr1b)
KMR: 108236972 108244668(ryr1b)
NWH: 119420597(ryr1a)
SSEN: 122773170(ryr1b) 122779385(ryr1a)
HHIP: 117772371(ryr1b) 117774331(ryr1a)
HSP: 118106529(ryr1b) 118122262(ryr1a)
XGL: 120791720(ryr1b) 120802314
BSPL: 114868419(ryr1b) 114869714
SASA: 106603084(ryr1)
PKI: 111838045 111841417(ryr1)
AANG: 118209433(ryr1b) 118236393
LOC: 102685847(ryr1)
LCM: 102356360(RYR1)
CMK: 103190328
RTP: 109927309
 » show all
Reference
PMID:2298749
  Authors
Zorzato F, Fujii J, Otsu K, Phillips M, Green NM, Lai FA, Meissner G, MacLennan DH
  Title
Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum.
  Journal
J Biol Chem 265:2244-56 (1990)
  Sequence
[hsa:6261]

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