KEGG   ORTHOLOGY: K05034
Entry
K05034                      KO                                     
Symbol
SLC6A1, GAT1
Name
solute carrier family 6 (neurotransmitter transporter, GABA) member 1
Pathway
map04721  Synaptic vesicle cycle
map04727  GABAergic synapse
Disease
H02361  Myoclonic-atonic epilepsy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    K05034  SLC6A1, GAT1; solute carrier family 6 (neurotransmitter transporter, GABA) member 1
   04721 Synaptic vesicle cycle
    K05034  SLC6A1, GAT1; solute carrier family 6 (neurotransmitter transporter, GABA) member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05034  SLC6A1, GAT1; solute carrier family 6 (neurotransmitter transporter, GABA) member 1
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC6: Sodium- and chloride-dependent neurotransmitter transporter
   K05034  SLC6A1, GAT1; solute carrier family 6 (neurotransmitter transporter, GABA) member 1
Other DBs
GO: 0005332
TC: 2.A.22.3.2
Genes
HSA: 6529(SLC6A1)
PTR: 460170(SLC6A1)
PPS: 100981601(SLC6A1)
GGO: 101127329(SLC6A1)
PON: 100449710(SLC6A1)
NLE: 100580505(SLC6A1)
MCC: 696617(SLC6A1)
MCF: 102143347(SLC6A1)
CSAB: 103228010(SLC6A1)
CATY: 105585785(SLC6A1)
PANU: 101020753(SLC6A1)
TGE: 112618493(SLC6A1)
RRO: 104673285(SLC6A1)
RBB: 108519327(SLC6A1)
TFN: 117083252(SLC6A1)
PTEH: 111546896(SLC6A1)
CJC: 100405198(SLC6A1)
SBQ: 101031662(SLC6A1)
CSYR: 103262033(SLC6A1)
MMUR: 105882654(SLC6A1)
OGA: 100949098(SLC6A1)
MMU: 232333(Slc6a1)
MCAL: 110296234(Slc6a1)
MPAH: 110315972(Slc6a1)
RNO: 79212(Slc6a1)
MCOC: 116099417(Slc6a1)
MUN: 110548920(Slc6a1)
CGE: 100760370(Slc6a1)
PLEU: 114689625(Slc6a1)
NGI: 103751440(Slc6a1)
HGL: 101716075(Slc6a1)
CPOC: 100731072(Slc6a1)
CCAN: 109701751(Slc6a1)
DORD: 105981309(Slc6a1)
DSP: 122108099(Slc6a1)
OCU: 103349186(SLC6A1)
OPI: 101532272(SLC6A1)
TUP: 102485460(SLC6A1)
CFA: 484655(SLC6A1)
VVP: 112933741(SLC6A1)
VLG: 121494959(SLC6A1)
AML: 100481037(SLC6A1)
UMR: 103669553(SLC6A1)
UAH: 113257173(SLC6A1)
UAR: 123799214(SLC6A1)
ELK: 111144145
LLV: 125108605
MPUF: 101684935(SLC6A1)
ORO: 101367494(SLC6A1)
EJU: 114207751(SLC6A1)
ZCA: 113918206(SLC6A1)
MLX: 118005393(SLC6A1)
FCA: 101088066(SLC6A1)
PYU: 121041258(SLC6A1)
PBG: 122487507(SLC6A1)
PTG: 102961904(SLC6A1)
PPAD: 109254358(SLC6A1)
AJU: 106972379(SLC6A1)
HHV: 120231329(SLC6A1)
BTA: 407118(SLC6A1)
BOM: 102272749(SLC6A1)
BIU: 109576154(SLC6A1)
BBUB: 102405939(SLC6A1)
CHX: 102188363(SLC6A1)
OAS: 101121462(SLC6A1)
ODA: 120868131(SLC6A1)
CCAD: 122424865(SLC6A1)
SSC: 100156668(SLC6A1)
CFR: 102511412(SLC6A1)
CBAI: 105067460(SLC6A1)
CDK: 105093110(SLC6A1)
VPC: 102525379(SLC6A1)
BACU: 103009674(SLC6A1)
LVE: 103072201(SLC6A1)
OOR: 101275449(SLC6A1)
DLE: 111168961(SLC6A1)
PCAD: 102985268(SLC6A1)
PSIU: 116762935(SLC6A1)
ECB: 100051613(SLC6A1)
EPZ: 103552729(SLC6A1)
EAI: 106835632(SLC6A1)
MYB: 102259217(SLC6A1)
MYD: 102768507(SLC6A1)
MMYO: 118668063(SLC6A1)
MLF: 102439601(SLC6A1)
MNA: 107534769(SLC6A1)
PKL: 118715217(SLC6A1)
HAI: 109387306(SLC6A1)
DRO: 112301146(SLC6A1)
SHON: 118990150(SLC6A1)
AJM: 119044801(SLC6A1)
PDIC: 114502113(SLC6A1)
PHAS: 123814556(SLC6A1)
MMF: 118633425(SLC6A1)
RFQ: 117037089(SLC6A1)
PALE: 102890590(SLC6A1)
PGIG: 120621460(SLC6A1)
PVP: 105299029(SLC6A1)
RAY: 107498365(SLC6A1)
MJV: 108394129(SLC6A1)
TOD: 119255560(SLC6A1)
SARA: 101551686(SLC6A1)
LAV: 100657816(SLC6A1)
TMU: 101354376
DNM: 101412982(SLC6A1)
MDO: 100015027(SLC6A1)
GAS: 123230705(SLC6A1)
SHR: 100926814(SLC6A1)
PCW: 110204875(SLC6A1)
OAA: 103164714(SLC6A1)
GGA: 415960(SLC6A1)
PCOC: 116226853 116239135(SLC6A1)
MGP: 100543038 104913133(SLC6A1)
CJO: 107315443 107319721(SLC6A1)
NMEL: 110395288 110404992(SLC6A1)
APLA: 101794982 101795056(SLC6A1)
ACYG: 106031043 106040072(SLC6A1)
AFUL: 116487081 116492894(SLC6A1)
TGU: 100222137 100225982(SLC6A1)
LSR: 110470656(SLC6A1) 110472974
SCAN: 103816940(SLC6A1) 103820452
PMOA: 120498371(SLC6A1) 120501614
OTC: 121332942 121348234(SLC6A1)
PRUF: 121362668 121365606(SLC6A1)
GFR: 102043122 102044604(SLC6A1)
FAB: 101813906(SLC6A1) 101814140
PHI: 102104120 102105393(SLC6A1)
PMAJ: 107204952 107210455(SLC6A1)
CCW: 104692231 104695752(SLC6A1)
ETL: 114062778 114069252(SLC6A1)
ZAB: 102070391(SLC6A1) 102073051
FPG: 101914729(SLC6A1) 101916548
FCH: 102050110 102052677(SLC6A1)
CLV: 102090229(SLC6A1) 102097632
EGZ: 104124317(SLC6A1) 104129752
NNI: 104020223 104022938(SLC6A1)
ACUN: 113485035(SLC6A1) 113491468
TALA: 104365626(SLC6A1) 104367816
PADL: 103921317(SLC6A1) 103924500
ACHC: 115333316(SLC6A1) 115352440
AAM: 106486664(SLC6A1) 106488559
AROW: 112963796(SLC6A1) 112968282
NPD: 112953080(SLC6A1) 112958308
DNE: 112984572(SLC6A1) 112993370
ASN: 102374525(SLC6A1) 102376042
AMJ: 102564359 102568842(SLC6A1)
CPOO: 109311413(SLC6A1) 109316474
GGN: 109289159(SLC6A1) 109296213
PSS: 102444650(SLC6A1) 102449895
CMY: 102941921(SLC6A1) 102943816
CPIC: 101942105 101951541(SLC6A1)
CABI: 116815467 116819616(SLC6A1)
ACS: 100551673 100556107(slc6a1)
PVT: 110076676 110083805(SLC6A1)
SUND: 121922760(SLC6A1) 121930358
PBI: 103056721(SLC6A1)
PMUR: 107302475(SLC6A1)
TSR: 106548627(SLC6A1)
PGUT: 117677844(SLC6A1)
VKO: 123016518 123034128(SLC6A1)
PMUA: 114591628(SLC6A1) 114605587
ZVI: 118080660(SLC6A1) 118091178
GJA: 107106031(SLC6A1) 107120217
XLA: 108704036 446294(slc6a1.S) 734186(XB5944457.S)
XTR: 100127682 100491859(slc6a1)
NPR: 108785471(SLC6A1) 108804619
RTEM: 120932692 120945272(SLC6A1)
BBUF: 120978674(SLC6A1) 121004206
BGAR: 122928505 122943280(SLC6A1)
DRE: 492490(slc6a1b) 568985(slc6a1l) 692318(slc6a1a)
IPU: 108255294(slc6a1b) 108276326(slc6a1a) 108279609(slc6a1l)
SMEO: 124399261(slc6a1a) 124400934(slc6a1l) 124402421(slc6a1b)
AMEX: 103034184 103035538(slc6a1)
EEE: 113572327 113583799(slc6a1)
ELY: 117249385(slc6a1l) 117257144(slc6a1b) 117258276(slc6a1a)
PLEP: 121946813 121957635(slc6a1b)
SLUC: 116051336(slc6a1b) 116059988 116062109(slc6a1a)
ECRA: 117938412(slc6a1l) 117943034(slc6a1b) 117947524(slc6a1a)
PPUG: 119194199(slc6a1b) 119211465 119221976
MSAM: 119886707(slc6a1b) 119906273(slc6a1a) 119918299(slc6a1l)
CUD: 121505319(slc6a1l) 121506016(slc6a1b) 121517961(slc6a1a)
OAU: 116309860(slc6a1l) 116313690(slc6a1b) 116331140(slc6a1a)
OML: 112144655(slc6a1b) 112152674 112158876(slc6a1a)
GAF: 122826657(slc6a1l) 122832982(slc6a1a) 122833633(slc6a1b)
CTUL: 119781379(slc6a1a) 119785662(slc6a1l) 119786486(slc6a1b)
GMU: 124857296(slc6a1b) 124871470(slc6a1a) 124882963
KMR: 108231587(slc6a1b) 108232048(slc6a1a) 108235073(slc6a1l)
NWH: 119411835(slc6a1b) 119417514(slc6a1a) 119428151(slc6a1l)
SSEN: 122766354(slc6a1l) 122768280(slc6a1b) 122777384(slc6a1a)
HHIP: 117756966 117761001(slc6a1b) 117764665(slc6a1a)
XGL: 120800387 120803665(slc6a1a) 120807157(slc6a1b)
AANG: 118211205(slc6a1b)
LOC: 102683526 102690331(slc6a1)
LCM: 102357144 102360179(SLC6A1)
CMK: 103186241 103190813(slc6a1b)
BFO: 118416081
BBEL: 109464977
DME: Dmel_CG1732(Gat)
DER: 6555853
DSE: 6619473
DSI: Dsimw501_GD27536(Dsim_GD27536)
DAN: 6495047
DSR: 110185425
DPE: 6601991
DMN: 108164510
DWI: 6651364
DGR: 6557185
DAZ: 108614590
DNV: 108652399
DHE: 111599784
DVI: 6623814
BOD: 106623653
SCAC: 106091802
LCQ: 111688143
ACOZ: 120958197
AARA: 120902709
AAG: 5573698
CPII: 120419023
CNS: 116340091
AME: 406071(Gat-a) 408381 494511(Gat-1B)
ATD: 109597327
NVL: 108559989
PPYR: 116166194
OTU: 111414272
BMOR: 101742290
BMAN: 114253530
MSEX: 115441249
BANY: 112056851
PPOT: 106111318
PXU: 106118550
PRAP: 111004306
ZCE: 119837579
HAW: 110379046
TNL: 113496240
OFU: 114364127
API: 100161653
DNX: 107170162
AGS: 114122802
RMD: 113552099
BTAB: 109038876
DCI: 103509991
HHAL: 106681409
NLU: 111049205
FOC: 113206252
ZNE: 110834937
CSEC: 111863525
FCD: 110862790
PVM: 113802098
PJA: 122257214
HAME: 121876668
PCLA: 123766166
PTRU: 123513336
HAZT: 108670654
TUT: 107366237
DPTE: 113796864
PTEP: 107443763
CEL: CELE_T03F7.1(snf-11) CELE_T13B5.1(snf-3)
CBR: CBG_07219(Cbr-snf-3) CBG_23167(Cbr-snf-11)
BMY: BM_BM5517(Bma-snf-11) BM_BM5758(Bma-snf-3)
TSP: Tsp_10901
PCAN: 112572460
BGT: 106057862
MYI: 110443918
OSN: 115231765
LAK: 106175411
PDAM: 113665820
CMT: CCM_02862
ANI: AN8966.2
 » show all
Reference
  Authors
Conti F, Minelli A, Melone M
  Title
GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications.
  Journal
Brain Res Brain Res Rev 45:196-212 (2004)
DOI:10.1016/j.brainresrev.2004.03.003
Reference
  Authors
Hahn MK, Blakely RD
  Title
The functional impact of SLC6 transporter genetic variation.
  Journal
Annu Rev Pharmacol Toxicol 47:401-41 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105242
Reference
  Authors
Thimgan MS, Berg JS, Stuart AE
  Title
Comparative sequence analysis and tissue localization of members of the SLC6 family of transporters in adult Drosophila melanogaster.
  Journal
J Exp Biol 209:3383-404 (2006)
DOI:10.1242/jeb.02328

DBGET integrated database retrieval system