KEGG ORTHOLOGY: K05193

ORTHOLOGY: K05193

Entry

K05193                      KO

Symbol

GLRA1

Name

glycine receptor alpha-1

Pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

Disease

H00769

Hyperekplexia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05193  GLRA1; glycine receptor alpha-1
   04082 Neuroactive ligand signaling
    K05193  GLRA1; glycine receptor alpha-1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05193  GLRA1; glycine receptor alpha-1
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05193  GLRA1; glycine receptor alpha-1
Membrane trafficking [BR:ko04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    K05193  GLRA1; glycine receptor alpha-1
Ion channels [BR:ko04040]
Ligand-gated channels
  Glycine
   K05193  GLRA1; glycine receptor alpha-1

Other DBs

GO:	0016934 0022824

TC:

1.A.9.3

Genes

HSA:	2741(GLRA1)

PTR:	471712(GLRA1)

PPS:	100987306(GLRA1)

GGO:	101141272(GLRA1)

PON:	100446940(GLRA1)

PPYG:

129036414(GLRA1)

NLE:	100583008(GLRA1)

HMH:	116471744(GLRA1)

SSYN:

129486132(GLRA1)

MCC:	713940(GLRA1)

MCF:	102120775(GLRA1)

MTHB:

126956605

MNI:	105466838(GLRA1)

CSAB:

103244821(GLRA1)

CATY:

105589915(GLRA1)

PANU:

100999328(GLRA1)

TGE:	112625699(GLRA1)

MLEU:

105543401(GLRA1)

RRO:	104658586(GLRA1)

RBB:	108532019(GLRA1)

TFN:	117065629(GLRA1)

PTEH:

111552671(GLRA1)

CANG:

105504259(GLRA1)

CJC:	100385045(GLRA1)

SBQ:	101053655(GLRA1)

CIMI:

108312555(GLRA1)

ANAN:

105724148(GLRA1)

CSYR:

103250962(GLRA1)

MMUR:

105858029(GLRA1)

LCAT:

123638046(GLRA1)

ERUF:

138393194(GLRA1)

PCOQ:

105821546(GLRA1)

OGA:	100962310(GLRA1)

MMU:	14654(Glra1)

MCAL:

110304789(Glra1)

MPAH:

110331539(Glra1)

RNO:	25674(Glra1)

MCOC:

116077391(Glra1)

ANU:	117710436(Glra1)

ASYL:

127694245(Glra1)

MUN:	110547209(Glra1)

CGE:	100761438(Glra1)

MAUA:

101839368(Glra1)

PROB:

127219853

PLEU:

114700415(Glra1)

PMAV:

102906840(Glra1)

MORG:

121456657(Glra1)

MFOT:

126510944

AAMP:

119812592(Glra1)

CNL:	130877686(Glra1)

NGI:	103749057(Glra1)

HGL:	101726680(Glra1)

CPOC:

100271906(Glra1)

CCAN:

109678684

DORD:

105998940(Glra1)

DSP:	122115452(Glra1)

DMER:

138827146(Glra1)

PLOP:

125342127(Glra1)

NCAR:

124986688

MMMA:

107148172(Glra1)

ITI:	101959519(Glra1)

OCU:

100344552

OPI:	101534556(GLRA1)

OCZ:	121153353(GLRA1)

TUP:	102497539(GLRA1)

CFA:	489172(GLRA1)

CLUD:

112651770(GLRA1)

VVP:	112928704(GLRA1)

VLG:	121486637(GLRA1)

NPO:	129509762(GLRA1)

AML:	100473634(GLRA1)

UMR:	103664570(GLRA1)

UAH:	113263875(GLRA1)

UAR:	123803677(GLRA1)

ELK:

111141152

LLV:

125099693

MPUF:

101692642(GLRA1)

MNP:	132027518(GLRA1)

MLK:	131831127(GLRA1)

NVS:	122902085(GLRA1)

ORO:	101384795(GLRA1)

EJU:	114211835(GLRA1)

ZCA:	113929473(GLRA1)

MLX:	118006816(GLRA1)

MANO:

123863019(GLRA1)

NSU:	110586929(GLRA1)

LWW:	102736068(GLRA1)

FCA:	101099022(GLRA1)

PYU:	121045424(GLRA1)

PCOO:

112860357(GLRA1)

PBG:	122493957(GLRA1)

PVIV:

125160244(GLRA1)

LRUF:

124507187

LGF:	123575860(GLRA1)

AJU:

106967687

PTG:	102964576(GLRA1)

PPAD:

109275992(GLRA1)

PUC:

125934522

PLEZ:

122225953(GLRA1)

HHV:	120236610(GLRA1)

CCRU:

144235498(GLRA1)

BTA:	281783(GLRA1)

BOM:	102265244(GLRA1)

BIU:	109561292(GLRA1)

BBUB:

102398235(GLRA1)

BKE:	129631018(GLRA1)

BBIS:

104996342(GLRA1)

CHX:	102169587(GLRA1)

OAS:	101107093(GLRA1)

BTAX:

128051220(GLRA1)

CSUM:

138085829(GLRA1)

ODA:	120863382(GLRA1)

CCAD:

122439192(GLRA1)

MREE:

136168520(GLRA1)

OVR:	110129516(GLRA1)

MBEZ:

129558745(GLRA1)

SSC:	100513384(GLRA1)

CFR:	102506085(GLRA1)

CBAI:

105080906(GLRA1)

CDK:	105095158(GLRA1)

VPC:	102528919(GLRA1)

BACU:

103006920(GLRA1)

BMUS:

118893235(GLRA1)

LVE:	103073547(GLRA1)

OOR:	101285733(GLRA1)

LALB:

132518413(GLRA1)

GMF:	115840747(GLRA1)

DDP:	132422385(GLRA1)

DLE:	111183010(GLRA1)

PCAD:

102977716(GLRA1)

PSIU:

116750687(GLRA1)

PPHC:

136120485(GLRA1)

NASI:

112402723(GLRA1)

ECB:	100060055(GLRA1)

EPZ:	103553362(GLRA1)

EAI:	106834927(GLRA1)

MYB:	102241661(GLRA1)

MYD:	102773364(GLRA1)

MMYO:

118657596(GLRA1)

MLF:	102423073(GLRA1)

MDT:	132235881(GLRA1)

MYUM:

139011607(GLRA1)

PKL:	118710729(GLRA1)

EFUS:

103295771(GLRA1)

MNA:	107538000(GLRA1)

DRO:	112319595(GLRA1)

SHON:

118986126(GLRA1)

AJM:	119057968(GLRA1)

PDIC:

114509869(GLRA1)

PHAS:

123810548(GLRA1)

MMF:	118615561(GLRA1)

PPAM:

129066373(GLRA1)

HAI:	109373446(GLRA1)

RFQ:	117016762(GLRA1)

PALE:

102896152(GLRA1)

PGIG:

120581599(GLRA1)

PVP:	105299474(GLRA1)

RAY:	107520502(GLRA1)

MJV:	108403464(GLRA1)

TOD:	119235489(GLRA1)

SARA:

101553877(GLRA1)

SFUM:

130021513(GLRA1)

SETR:

126015503(GLRA1)

LAV:	100671428(GLRA1)

TMU:

101353025

ETF:	101642087(GLRA1)

DNM:	101439953(GLRA1)

MDO:	100029574(GLRA1)

GAS:	123233815(GLRA1)

SHR:	100923382(GLRA1)

AFZ:

127550115

PCW:	110192883(GLRA1)

TVP:	118843885(GLRA1)

PBRV:

138172570(GLRA1)

MLAO:

141502688(GLRA1)

OAA:	100077594(GLRA1)

TACU:

119919607(GLRA1)

GGA:	427637(GLRA1)

PCOC:

116231916(GLRA1)

MGP:	100546420(GLRA1)

CJO:	107320237(GLRA1)

TPAI:

128081453(GLRA1)

LMUT:

125700145(GLRA1)

NMEL:

110405503(GLRA1)

APLA:

101805435(GLRA1)

AACU:

137864335(GLRA1)

OJA:	118173748(GLRA1)

ACYG:

106032839(GLRA1)

CATA:

118254493(GLRA1)

AFUL:

116494813(GLRA1)

TGU:	115490550(GLRA1)

LSR:	110482687(GLRA1)

VMC:	128814994(GLRA1)

VCHA:

128795753(GLRA1)

AIB:	137483107(GLRA1)

SCAN:

103817322(GLRA1)

PMOA:

120498583(GLRA1)

OTC:	121332345(GLRA1)

PRUF:

121361387(GLRA1)

ATRC:

139597749(GLRA1)

MATE:

118692084(GLRA1)

MAEN:

136562953(GLRA1)

GFR:	102034100(GLRA1)

FAB:	101816523(GLRA1)

OMA:	130258704(GLRA1)

PHI:	102099879(GLRA1)

PMAJ:

107210892(GLRA1)

CCAE:

111935517(GLRA1)

CCW:	104689561(GLRA1)

CBRC:

103611417(GLRA1)

ACOE:

138118095(GLRA1)

ETL:	114065601(GLRA1)

ZAB:	102062936(GLRA1)

ZLE:	135453900(GLRA1)

ACHL:

103798404(GLRA1)

SVG:	106859559(GLRA1)

MMEA:

130579366(GLRA1)

HRT:	120759183(GLRA1)

SATI:

136367301(GLRA1)

CFAI:

136297218(GLRA1)

CCIC:

134049466(GLRA1)

FPG:	101921100(GLRA1)

FCH:	102049885(GLRA1)

FRS:	119153019(GLRA1)

CCRI:

104165578(GLRA1)

NNT:	104407207(GLRA1)

SHAB:

115616026(GLRA1)

ACUN:

113485150(GLRA1)

ANOC:

141964895(GLRA1)

SURA:

141949619(GLRA1)

TALA:

104368056(GLRA1)

ACHC:

115334175(GLRA1)

HALD:

104317647(GLRA1)

HLE:	104838920(GLRA1)

AGEN:

126050831

HHAR:

128134440(GLRA1)

BBUT:

142044200(GLRA1)

GCL:

127021902

CSTI:

104557071

LDI:	104353432(GLRA1)

MNB:	103773803(GLRA1)

DPUB:

104309363(GLRA1)

PPUS:

135185023(GLRA1)

IIN:	128972904(GLRA1)

AVIT:

104267147(GLRA1)

BRHI:

104498582(GLRA4)

EGZ:	104123111(GLRA1)

NNI:	104014213(GLRA1)

PCRI:

104032807(GLRA1)

PCAO:

104043320(GLRA1)

PARX:

142061505(GLRA1)

PADL:

103915731(GLRA1)

AFOR:

103904368(GLRA1)

FGA:

104082459

CBOR:

142088673(GLRA1)

GSTE:

104256402

CBOY:

140656606(GLRA1)

MAME:

142413436(GLRA1)

CLV:	102092412(GLRA1)

CNIC:

135993744(GLRA1)

MUI:

104540244

PGUU:

104464344(GLRA1)

PLET:

104627873(GLRA1)

EHS:	104506613(GLRA1)

CMAC:

104487715(GLRA1)

CUCA:

104059686(GLRA1)

PCUR:

138726948(GLRA1)

TEO:	104376992(GLRA1)

BREG:

104639724

GAME:

129212769(GLRA1)

OHA:	104336755(GLRA1)

ACAR:

104526041(GLRA1)

CPEA:

104392599(GLRA1)

CVF:	104293131(GLRA1)

RTD:	128916225(GLRA1)

CRID:

134522155(GLRA1)

NARQ:

141469838(GLRA1)

AAM:	106493605(GLRA1)

AROW:

112966487(GLRA1)

NPD:	112954476(GLRA1)

TGT:	104572756(GLRA1)

DNE:	112994294(GLRA1)

SCAM:

104151064(GLRA1)

ASN:	102377170(GLRA1)

AMJ:	102562960(GLRA1)

CPOO:

109310298(GLRA1)

GGN:	109290088(GLRA1)

PSS:	102447313(GLRA1)

CIZ:	142021157(GLRA1)

CMY:	102947340(GLRA1)

CCAY:

125641764(GLRA1)

LKP:	140916476(GLRA1)

NDS:	141991873(GLRA1)

DCC:	119860221(GLRA1)

CPIC:

101932156(GLRA1)

TST:	117882053(GLRA1)

EOB:	135882974(GLRA1)

CABI:

116820071(GLRA1)

MRV:	120371036(GLRA1)

ACS:	100560473(glra1)

ASAO:

132768981(GLRA1)

PVT:	110089760(GLRA1)

SUND:

121922756(GLRA1)

PBI:	103066914(GLRA1)

PMUR:

107293200(GLRA1)

CTIG:

120304793(GLRA1)

TSR:	106550117(GLRA1)

PGUT:

117654990(GLRA1)

PCAE:

139309680(GLRA1)

APRI:

131190516(GLRA1)

PTEX:

113433519(GLRA1)

NSS:	113424270(GLRA1)

VKO:	123035808(GLRA1)

PMUA:

114591374(GLRA1)

PRAF:

128407984(GLRA1)

ZVI:	118080447(GLRA1)

HCG:	128342166(GLRA1)

GJA:	107113895(GLRA1)

STOW:

125430047(GLRA1)

EMC:	129328579(GLRA1)

XLA:	108710191 108712269(glra1.S)

XTR:	100498379(glra1)

NPR:	108786321(GLRA1)

RTEM:

120932609(GLRA1)

ACAT:

141132566(GLRA1)

PADS:

140323422(GLRA1)

BBUF:

121004574(GLRA1)

BGAR:

122926072(GLRA1)

DTC:	141083582(GLRA1)

HSQ:	130267308(GLRA1)

PCOB:

134933271(GLRA1)

PWL:	138245731(GLRA1)

MUO:	115476845(GLRA1)

GSH:	117351834(GLRA1)

DRE:	30676(glra1)

SRX:	107717398 107741059(glra1)

SANH:

107662012 107664787(glra1)

SGH:	107567205(glra1) 107598350

CCAR:

109057001(glra1) 109093737

CAUA:

113057822 113114269

CGIB:

127971682 128027014

PTET:

122358288(glra1)

LROH:

127176313(glra1)

GRF:	141288710(glra1)

OMC:	131553763(glra1)

PPRM:

120484932(glra1)

RKG:	130084860(glra1)

MAMB:

125259197(glra1)

CIDE:

127494636

CERY:

137006379(glra1)

MASI:

127412947 127417997

TROS:

130563911(glra1)

TDW:	130437821(glra1)

MANU:

129422803(glra1)

PDAB:

135753571(glra1)

IPU:

108269080

IFU:	128611462(glra1)

PHYP:

113529338(glra1)

SMEO:

124386475(glra1)

TFD:	113636015(glra1)

TVC:	132856240(glra1)

CGAR:

128531257(glra1)

NGRA:

132890205(glra1)

TRN:	134319429(glra1)

AMEX:

103026517(glra1)

CMAO:

118806860(glra1)

EEE:	113573358(glra1)

CHAR:

105906259(glra1)

SPIL:

134068828(glra1)

ASAD:

121694608(glra1)

TFS:	130531890(glra1)

TNG:	GSTEN00024269G001

LCO:	104928619(glra1)

TBEN:

117472509(glra1)

CGOB:

115014561(glra1)

PGEO:

117453965(glra1)

GACU:

117549664(glra1)

EMAC:

134860341(glra1)

ELY:	117253309(glra1)

EFO:	125894089(glra1)

PLEP:

121947790(glra1)

SLUC:

116062441(glra1)

SVIT:

144524883(glra1)

ECRA:

117951899(glra1)

ESP:	116696545(glra1)

PFLV:

114562830(glra1)

PFLT:

120566596(glra1)

GAT:	120817819(glra1)

PPUG:

119210637(glra1)

AFB:	129089784(glra1)

CLUM:

117737247(glra1)

PSWI:

130209334(glra1)

CANA:

137782646(glra1)

CVE:	137875098(glra1)

MSAM:

119889450(glra1)

SCHU:

122880769(glra1)

EARM:

139291108(glra1)

CUD:	121516549(glra1)

SPUL:

138598124(glra1)

LMIX:

132982220(glra1)

HTC:	141793271(glra1)

ALAT:

119007817(glra1)

ASTR:

137602386(glra1)

PKLU:

139207067(glra1)

MZE:	101470314(glra1)

ONL:	100697877(glra1)

OAU:	116325405(glra1)

OLA:	101173557(glra1)

OML:	112137874(glra1)

CSAI:

133446720(glra1)

XMA:	102228647(glra1)

XCO:	114139370(glra1)

XHE:	116714244(glra1)

PRET:

103471669(glra1)

PFOR:

103140094(glra1)

PLAI:

106949801(glra1)

PMEI:

106927327(glra1)

GAF:	122837191(glra1)

PPRL:

129360466 129360471

CVG:	107082688(glra1)

CTUL:

119790084(glra1)

GMU:	124860374(glra1)

NFU:	107380703(glra1)

KMR:	108243973(glra1)

ALIM:

106523913 106532799(glra1)

NWH:	119408641(glra1)

AOCE:

111578099(glra1)

EJA:	138210333(glra1)

BFRE:

138627625(glra1)

MCEP:

125007821(glra1)

CSEM:

103391091(glra1)

POV:

109633322

SSEN:

122778524(glra1)

SSOE:

131472370(glra1)

HSP:	118112770(glra1)

SMAU:

118319666(glra1)

LCF:

108882480

SDU:

111232632

SLAL:

111662569(glra1)

XGL:	120785833(glra1)

HCQ:	109516672(glra1)

SSCV:

125987700(glra1)

SBIA:

133508288(glra1)

PTAO:

133484284(glra1)

BPEC:

110156357(glra1)

ENY:	140354809(glra1) 140357115

MALB:

109956745(glra1)

BSPL:

114864187(glra1)

SJO:	128363218(glra1)

SSCO:

133985976(glra1)

TTY:	137189915(glra1)

GMH:	115552815(glra1)

SASA:

106604187 106604188 106612254(glra1)

STRU:

115167237 115205723

OTW:	112220587 121846945(glra1)

OMY:	110489213(glra1) 110504553

OGO:	123993723 124010466(glra1)

ONE:	115116885 115124557

OKI:	109878039 109910214

OKE:	118373580 118375185(glra1)

OMM:	135526748 135545480

OCLA:

139366558 139397371 139397477

SALP:

111965595 112081117

SNH:	120047816 120062176

SFON:

129827438 129858487

CCLU:

121530797 121538721(glra1)

ELS:	105030026(glra1)

OEP:	134032329(glra1)

SFM:	108922912(glra1)

PKI:	111836307(glra1)

AANG:

118222123(glra1)

AROT:

135251072(glra1)

CCOG:

133124321(glra1)

LOC:	102684263(glra1)

PSPA:

121296821 121323762

ARUT:

117413486 117431026

PSEX:

120543045(glra1)

LCM:	102352455(GLRA1)

CMK:	103184176(glra1)

RTP:	109938500(glra1)

CPLA:

122556517(glra1)

CPUN:

140491957(glra1)

HOC:	132823248(glra1)

SCAU:

119965383(glra1)

STOZ:

140427091

LERI:

129701861

HAKA:

140739213(glra1)

PMRN:

116957524 116957526

LRJ:	133339571 133339621 133339638 133339647 133339654

BFO:	118417064 118422798

BBEL:

109481152 109481313 109481957 109483208

LPIC:

129257456 129283933

LVG:

121411490

AJJ:

139978945

ARUN:

117288222 117288408 117301030

AAMU:

139937262

SKO:

102804758

PFLL:

139115091 139115857 139115862 139115868 139116297 139116457 139121404 139121554 139121764 139131532 139134853 139136929 139140155 139140156 139147063 139147065

CCIN:

107272502

PJA:	122244521 122247083 122258223

PCHN:

125024613 125026304

HAME:

121857766 121873808 121874216

PCLA:

123769824

PTRU:

123505819 123509455 123511912

MNZ:

135201706

MRJ:

136849874

HAZT:

108678427 108678438

OOT:	143018107 143037581

EAF:

111713981

LSM:	121122259 121123324

TCF:	131883573 131885330

DSV:	119456073 119456836

DALB:

135916463

RSAN:

119393622 119394912 119394916

RMP:	119172711 119172832 119179367 119183055

DFR:

124500382

CVS:	136980421 136980767 136981779 136981780

PTEP:

107456705

ABRU:

129976481

UDV:	129224770 129231003

SDM:	118195359 118195498 118195799 118199873 118199934

LPOL:

106458413 106461487 106478190

PVUL:

126829283

LSAX:

138968969

BARL:

143283871 143298595 143298970 143300529

GAE:	121369150 121374632

HRF:	124139621 124141840

HRJ:	124276828 124282170

HASI:

137272842

HCRA:

139449597

CRG:	105327474 105331127

CANU:

128156445 128156923

CVN:	111122821 111123723 111125046 111126221 111126896

OED:	125681415 125681993

MYI:

PMAX:

AIRR:

YBA:

MMER:

123528004 123556549 123557060 123558139

RPHI:

132728176

DPOL:

127879805 127879813

MAEA:

128226702 128227249

OSN:	115214289 115218542

LJP:	135467571 135472260 135472411 135472943

EGL:

EGR_04431

LLON:

135493427 135493652 135493724 135501668

NVE:	5506821 5511687 5511690 5512620

EPA:	110241673 110241678

ATEN:

116288295 116288314 116298085 116298091

AMIL:

114968728

MCAZ:

138016593 138050632

MFOO:

137997046 138000717

PDAM:

113668682 113675098 113687048

SPIS:

111331321 111331360

XEN:

124445325

HSY:	130614433 130648925

RES:

135686797

CCLM:

134193980

» show all

Reference

PMID:2155780

Authors

Grenningloh G, Schmieden V, Schofield PR, Seeburg PH, Siddique T, Mohandas TK, Becker CM, Betz H

Title

Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

Journal

EMBO J 9:771-6 (1990)
DOI:10.1002/j.1460-2075.1990.tb08172.x

Sequence

[hsa:2741]

All links

Ontology (3)   
   GO (2)   
   TC (1)   
Gene (483)   
   MGENES (77)   
   RefGene (402)   
   OC (4)   
All databases (486)   

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