KEGG   ORTHOLOGY: K05473
Entry
K05473                      KO                                     

Symbol
TNFSF11, RANKL, CD254
Name
tumor necrosis factor ligand superfamily member 11
Pathway
map04060  Cytokine-cytokine receptor interaction
map04064  NF-kappa B signaling pathway
map04380  Osteoclast differentiation
map04917  Prolactin signaling pathway
map04928  Parathyroid hormone synthesis, secretion and action
map05207  Chemical carcinogenesis - receptor activation
map05224  Breast cancer
map05323  Rheumatoid arthritis
Disease
H00436  Osteopetrosis
H01470  Giant cell tumor of bone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04928 Parathyroid hormone synthesis, secretion and action
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09162 Cancer: specific types
   05224 Breast cancer
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04090 CD molecules
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Tumor necrosis fators
   K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
CD molecules [BR:ko04090]
 Proteins
  K05473  CD254, TNFSF11; tumor necrosis factor (ligand) superfamily, member 11
Other DBs
GO: 0005164
Genes
HSA: 8600(TNFSF11)
PTR: 467353(TNFSF11)
PPS: 100994539(TNFSF11)
GGO: 101131644(TNFSF11)
PON: 100439883(TNFSF11)
NLE: 100599838(TNFSF11)
MCC: 699955(TNFSF11)
MCF: 102137946(TNFSF11)
CSAB: 103214344(TNFSF11)
CATY: 105587810(TNFSF11)
PANU: 101026064(TNFSF11)
RRO: 104671084(TNFSF11)
RBB: 108514105(TNFSF11)
TFN: 117096667(TNFSF11)
PTEH: 111540414(TNFSF11)
CJC: 100401379(TNFSF11)
SBQ: 101051208(TNFSF11)
MMUR: 105869318(TNFSF11)
MMU: 21943(Tnfsf11)
MCAL: 110309649(Tnfsf11)
MPAH: 110325778(Tnfsf11)
RNO: 117516(Tnfsf11)
MCOC: 116084439(Tnfsf11)
MUN: 110562414(Tnfsf11)
CGE: 100768715(Tnfsf11)
PLEU: 114699851(Tnfsf11)
NGI: 103751291(Tnfsf11)
HGL: 101696350(Tnfsf11)
CCAN: 109700348(Tnfsf11)
OCU: 100341009(TNFSF11)
TUP: 102487682(TNFSF11)
CFA: 609418(TNFSF11)
VVP: 112928102(TNFSF11)
VLG: 121477078(TNFSF11)
AML: 100483079(TNFSF11)
UMR: 103677566(TNFSF11)
UAH: 113251369(TNFSF11)
ORO: 101376926(TNFSF11)
ELK: 111147123
MPUF: 101672512 101682798(TNFSF11)
EJU: 114211677(TNFSF11)
MLX: 118009176(TNFSF11)
FCA: 724036(TNFSF11)
PTG: 102954463(TNFSF11)
PPAD: 109265885(TNFSF11)
AJU: 106971982(TNFSF11)
HHV: 120248657(TNFSF11)
BTA: 513836(TNFSF11)
BOM: 102267691(TNFSF11)
BIU: 109566677(TNFSF11)
BBUB: 102393260(TNFSF11)
CHX: 102176335(TNFSF11)
OAS: 100037694(TNFSF11)
ODA: 120883183(TNFSF11)
SSC: 100037976(TNFSF11)
CFR: 102507742(TNFSF11)
CBAI: 105083435(TNFSF11)
CDK: 105089768(TNFSF11)
BACU: 103002678(TNFSF11)
LVE: 103074658(TNFSF11)
OOR: 101284929(TNFSF11)
DLE: 111175123(TNFSF11)
PCAD: 102978976(TNFSF11)
ECB: 100060254(TNFSF11)
EPZ: 103560371(TNFSF11)
EAI: 106847554(TNFSF11)
MYB: 102260756(TNFSF11)
MYD: 102751742(TNFSF11)
MMYO: 118651542(TNFSF11)
MNA: 107531354(TNFSF11)
HAI: 109386844(TNFSF11)
DRO: 112311127(TNFSF11)
SHON: 118997034(TNFSF11)
AJM: 119042868(TNFSF11)
MMF: 118622793(TNFSF11)
PALE: 102896284(TNFSF11)
PGIG: 120614450(TNFSF11)
RAY: 107517455(TNFSF11)
MJV: 108407315(TNFSF11)
TOD: 119259662(TNFSF11)
LAV: 100663523(TNFSF11)
TMU: 101342165
MDO: 100011641(TNFSF11)
SHR: 105750026(TNFSF11)
PCW: 110201421(TNFSF11)
OAA: 100076541(TNFSF11)
GGA: 428067(TNFSF11)
PCOC: 116244153(TNFSF11)
MGP: 104917524(TNFSF11)
CJO: 107308113(TNFSF11)
NMEL: 110387248(TNFSF11)
APLA: 101803149(TNFSF11)
ACYG: 106035087(TNFSF11)
TGU: 100227247(TNFSF11)
LSR: 110470890(TNFSF11)
SCAN: 103812581(TNFSF11)
PMOA: 120505810(TNFSF11)
GFR: 102038556(TNFSF11)
FAB: 101822088(TNFSF11)
PHI: 102111124(TNFSF11)
PMAJ: 107212828(TNFSF11)
CCAE: 111935210(TNFSF11)
CCW: 104693175(TNFSF11)
ETL: 114059881(TNFSF11)
FPG: 101919009(TNFSF11)
FCH: 102050665(TNFSF11)
CLV: 102098042(TNFSF11)
EGZ: 104132030(TNFSF11)
NNI: 104010922(TNFSF11)
ACUN: 113480179(TNFSF11)
PADL: 103915905(TNFSF11)
AAM: 106489200(TNFSF11)
ASN: 102387902(TNFSF11)
AMJ: 102559854(TNFSF11)
CPOO: 109305514(TNFSF11)
GGN: 109302252(TNFSF11)
PSS: 102444457(TNFSF11)
CMY: 102947527(TNFSF11)
CPIC: 101936501(TNFSF11)
TST: 117871596(TNFSF11)
CABI: 116817999(TNFSF11)
ACS: 100566737(tnfsf11)
PVT: 110084678(TNFSF11)
PMUR: 107283208(TNFSF11)
PGUT: 117667006(TNFSF11)
PMUA: 114600094(TNFSF11)
ZVI: 118079346(TNFSF11)
GJA: 107123862(TNFSF11)
XLA: 496322(tnfsf11.L) 733333(tnfsf11.S)
XTR: 100038074(tnfsf11)
NPR: 108790250(TNFSF11)
SRX: 107713713 107749039(tnfsf11)
SANH: 107661329(tnfsf11) 107688674
SGH: 107580040
EEE: 113582613
TRU: 101080086
LCO: 104934832
MSAM: 119885223 119904577(tnfsf11)
MZE: 101482899(tnfsf11)
ONL: 100690570
OAU: 116310490(tnfsf11)
XMA: 102231551(tnfsf11)
XCO: 114148628(tnfsf11)
PRET: 103481812(tnfsf11)
CVG: 107101899
NFU: 107389518(tnfsf11)
KMR: 108245125(tnfsf11)
ALIM: 106511186
AOCE: 111568245
CSEM: 103391567(tnfsf11)
POV: 109642694
HCQ: 109514543(tnfsf11)
BPEC: 110170617(tnfsf11)
MALB: 109971659
SFM: 108920497(tnfsf11) 108928984
LCM: 102363811(TNFSF11)
SPU: 115922601
 » show all
Reference
PMID:9367155
  Authors
Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L
  Title
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
  Journal
Nature 390:175-9 (1997)
DOI:10.1038/36593
  Sequence
[hsa:8600]

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