KEGG   ORTHOLOGY: K05742
Entry
K05742                      KO                                     

Symbol
SLC9A1, NHE1
Name
solute carrier family 9 (sodium/hydrogen exchanger), member 1
Pathway
map04024  cAMP signaling pathway
map04260  Cardiac muscle contraction
map04261  Adrenergic signaling in cardiomyocytes
map04371  Apelin signaling pathway
map04810  Regulation of actin cytoskeleton
map04919  Thyroid hormone signaling pathway
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05205  Proteoglycans in cancer
Disease
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04024 cAMP signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04261 Adrenergic signaling in cardiomyocytes
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
  09154 Digestive system
   04970 Salivary secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04971 Gastric acid secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04972 Pancreatic secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04976 Bile secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC9: Na+/H+ exchanger
   K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
Other DBs
GO: 0015385
TC: 2.A.36.1.1 2.A.36.1.4
Genes
HSA: 6548(SLC9A1)
PTR: 456669(SLC9A1)
PPS: 100995124(SLC9A1)
GGO: 101134383(SLC9A1)
PON: 100450045(SLC9A1)
NLE: 100581293(SLC9A1)
MCC: 720079(SLC9A1)
MCF: 101865259(SLC9A1)
CSAB: 103225299(SLC9A1)
CATY: 105594911(SLC9A1)
PANU: 101025420(SLC9A1)
RRO: 104675732(SLC9A1)
RBB: 108518204(SLC9A1)
TFN: 117093042(SLC9A1)
PTEH: 111547635(SLC9A1)
CJC: 100388466(SLC9A1)
SBQ: 101042099(SLC9A1)
MMUR: 105863538(SLC9A1)
MMU: 20544(Slc9a1)
MCAL: 110292287(Slc9a1)
MPAH: 110322856(Slc9a1)
RNO: 24782(Slc9a1)
MCOC: 116096786(Slc9a1)
MUN: 110552459(Slc9a1)
CGE: 100689320(Slc9a1)
PLEU: 114705938(Slc9a1)
NGI: 103737082(Slc9a1)
HGL: 101724784(Slc9a1)
CCAN: 109698756(Slc9a1)
OCU: 100009586(SLC9A1)
TUP: 102501147(SLC9A1)
CFA: 478171(SLC9A1)
VVP: 112931659(SLC9A1)
VLG: 121497607(SLC9A1)
AML: 100478707(SLC9A1)
UMR: 103666507(SLC9A1)
UAH: 113268442(SLC9A1)
ORO: 101369980(SLC9A1)
MPUF: 101671364(SLC9A1)
EJU: 114216990(SLC9A1)
MLX: 118019822(SLC9A1)
FCA: 101088766(SLC9A1)
PTG: 102956531(SLC9A1)
PPAD: 109256776(SLC9A1)
AJU: 106977548(SLC9A1)
HHV: 120231816(SLC9A1)
BTA: 317654(SLC9A1)
BOM: 102275424(SLC9A1)
BIU: 109573208(SLC9A1)
BBUB: 102403111(SLC9A1)
CHX: 102179249(SLC9A1)
OAS: 494435(SLC9A1)
ODA: 120855120(SLC9A1)
SSC: 397458(SLC9A1)
CFR: 102517893(SLC9A1)
CBAI: 105063448(SLC9A1)
CDK: 105100703(SLC9A1)
BACU: 103013771(SLC9A1)
LVE: 103083053(SLC9A1)
OOR: 101272326(SLC9A1)
DLE: 111163304(SLC9A1)
PCAD: 102979091(SLC9A1)
ECB: 100070959(SLC9A1)
EPZ: 103550531(SLC9A1)
EAI: 106839089(SLC9A1)
MYB: 102260344(SLC9A1)
MYD: 102754223(SLC9A1)
MMYO: 118675346(SLC9A1)
MNA: 107540015(SLC9A1)
HAI: 109386737(SLC9A1)
DRO: 112299258(SLC9A1)
SHON: 118977748(SLC9A1)
AJM: 119052315(SLC9A1)
MMF: 118626285(SLC9A1)
PALE: 102888463(SLC9A1)
PGIG: 120595972(SLC9A1)
RAY: 107503560(SLC9A1)
MJV: 108383513(SLC9A1)
TOD: 119235177(SLC9A1)
LAV: 104846349(SLC9A1)
TMU: 101342248
MDO: 100017140(SLC9A1)
SHR: 100927417(SLC9A1)
PCW: 110206146(SLC9A1)
OAA: 100088668(SLC9A1)
GGA: 419580(SLC9A1)
PCOC: 116230104(SLC9A1)
MGP: 100008573(SLC9A1)
CJO: 107323990(SLC9A1)
NMEL: 110387336(SLC9A1)
APLA: 101803574(SLC9A1)
ACYG: 106047889(SLC9A1)
TGU: 100229450(SLC9A1)
LSR: 110472858(SLC9A1)
SCAN: 103823594(SLC9A1)
PMOA: 120513847(SLC9A1)
GFR: 102032850(SLC9A1)
FAB: 101817623(SLC9A1)
PHI: 102103995(SLC9A1)
PMAJ: 107214153(SLC9A1)
CCAE: 111938953(SLC9A1)
ETL: 114068051(SLC9A1)
FPG: 101911642(SLC9A1)
FCH: 102059778(SLC9A1)
CLV: 102086647(SLC9A1)
EGZ: 104134879(SLC9A1)
NNI: 104017832(SLC9A1)
ACUN: 113488369(SLC9A1)
PADL: 103925878(SLC9A1)
ASN: 102370779(SLC9A1)
AMJ: 102575554(SLC9A1)
CPOO: 109318619(SLC9A1)
GGN: 109294195(SLC9A1)
PSS: 102447706(SLC9A1)
CMY: 102944004(SLC9A1)
CPIC: 101944127(SLC9A1)
TST: 117868272(SLC9A1)
CABI: 116837951(SLC9A1)
ACS: 100555032(slc9a1)
PVT: 110090947(SLC9A1)
PBI: 103064198(SLC9A1)
PMUR: 107294309(SLC9A1)
TSR: 106544692(SLC9A1)
PGUT: 117663527(SLC9A1)
PMUA: 114601510(SLC9A1)
ZVI: 118086339(SLC9A1)
GJA: 107110810(SLC9A1)
XLA: 108708100(slc9a1.L) 397917(slc9a1.S)
XTR: 100496739(slc9a1)
NPR: 108790812(SLC9A1)
DRE: 101885761(slc9a1a) 795135(slc9a1b)
SRX: 107713848(slc9a1) 107737341
PHYP: 113525374 113532843(slc9a1)
AMEX: 103040045(slc9a1) 103046642
EEE: 113583546(slc9a1) 113590159
NCC: 104952406 104953974(slc9a1)
CGOB: 115015521 115020992(slc9a1)
ELY: 117263830 117265759(slc9a1a)
PLEP: 121945900(slc9a1a) 121957776
SLUC: 116047130 116060760(slc9a1a)
ECRA: 117946136(slc9a1a) 117956214
GAT: 120810001(slc9a1a) 120826957
MSAM: 119897251(slc9a1a) 119907251
CUD: 121513220(slc9a1a) 121523741
MZE: 101464569 101464596(slc9a1)
OAU: 116315166 116320903(slc9a1a)
OML: 112137653 112143495(slc9a1a)
XMA: 102218019 102232120(slc9a1)
CTUL: 119777459(slc9a1a) 119790508
KMR: 108240374(slc9a1a) 108247901
SLAL: 111649465 111651770(slc9a1)
XGL: 120784304(slc9a1a) 120786347
HCQ: 109515389(slc9a1) 109516318
OMY: 100136740(slc9a1b) 110488849 110517020(slc9a1a)
SFM: 108919129
AANG: 118230682(slc9a1a) 118233475
LOC: 102687426(slc9a1)
PSPA: 121308281
LCM: 102351735(SLC9A1)
CMK: 103179577(slc9a1)
RTP: 109914572(slc9a1)
CSEC: 111868361
HAME: 121869039
HAZT: 108675073
CBR: CBG17545(Cbr-pbo-4)
PCAN: 112555699
OBI: 106873157
ADF: 107329791
AQU: 100637760
 » show all
Reference
PMID:2536298
  Authors
Sardet C, Franchi A, Pouyssegur J
  Title
Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter.
  Journal
Cell 56:271-80 (1989)
DOI:10.1016/0092-8674(89)90901-X
  Sequence
[hsa:6548]

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