KEGG   ORTHOLOGY: K05783
Entry
K05783                      KO                                     
Symbol
benD-xylL
Name
dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]
Pathway
map00362  Benzoate degradation
map00364  Fluorobenzoate degradation
map00622  Xylene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
   00364 Fluorobenzoate degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
   00622 Xylene degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.25  1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
     K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
    1.3.1.-
     K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K05783
Other DBs
RN: R00813 R05292 R05293 R05309 R05314 R08111 R08112 R08113
COG: COG1028
GO: 0047116
Genes
EFE: EFER_1485(benD)
KPN: KPN_01869
KPU: KP1_2934
KPM: KPHS_28390
KPP: A79E_2376
KPH: KPNIH24_14210(benD)
KPZ: KPNIH27_13570(benD)
KPV: KPNIH29_14240(benD)
KPW: KPNIH30_14505(benD)
KPY: KPNIH31_13520(benD)
KPG: KPNIH32_14400(benD)
KPC: KPNIH10_14040(benD)
KPQ: KPR0928_14020(benD)
KPO: KPN2242_12265(benD)
KPR: KPR_2933(benD)
KPJ: N559_2421
KPI: D364_09585(benD)
KPX: PMK1_04210(lvr)
KPB: FH42_05420(benD)
KPNE: KU54_012115(benD)
KPNU: LI86_12050(benD)
KPNK: BN49_2969(benD)
KVA: Kvar_2435
KPE: KPK_2488(cbeD)
KPK: A593_24210(benD)
KVD: KR75_22145(benD)
KVQ: SP68_02890(benD)
KOC: AB185_22235(benD)
KQU: AVR78_18380(benD)
EAE: EAE_19880(benD)
EAR: CCG29904
KQV: B8P98_13160(benD)
ROR: RORB6_06755(benD)
RON: TE10_13830(benD)
RPLN: B1209_13860(benD)
RTG: NCTC13098_03815(lvr_2)
CFAR: CI104_13175(benD)
CIR: C2U53_22220(benD)
PGE: LG71_16210(benD)
PSGC: G163CM_11650(lvr)
EBF: D782_2133
EBU: CUC76_01775(benD)
SMAF: D781_2850
SERM: CLM71_14595(benD)
SFJ: SAMEA4384070_3090(xecD)
SSUR: ATE40_011850(benD)
XSA: SB85_10140(benD)
PSD: DSC_14910(benD)
VNA: PN96_18365(benD)
VEJ: VEJY3_17926(benD)
VJP: NP165_16980(benD)
PAE: PA2515(xylL)
PAEV: N297_2586
PAEI: N296_2586
PAU: PA14_32130(xylL)
PAP: PSPA7_2722(xylL)
PAG: PLES_27801(xylL)
PAF: PAM18_2524(benD)
PNC: NCGM2_3520(benD)
PAEB: NCGM1900_4012(benD)
PDK: PADK2_12670(benD)
PSG: G655_12450(benD)
PRP: M062_13075(benD)
PAEP: PA1S_13070(benD)
PAEM: U769_12650(benD)
PAEL: T223_14270(benD)
PAEU: BN889_02739(benD)
PAEG: AI22_20850(benD)
PAEC: M802_2583
PAEO: M801_2451
PMK: MDS_4167
PRE: PCA10_30910(benD)
PPSE: BN5_3608(benD)
PCQ: PcP3B5_23360(lvr)
PPU: PP_3164(benD)
PPF: Pput_2551
PPT: PPS_2762
PPB: PPUBIRD1_2569(benD)
PPI: YSA_10652
PPX: T1E_1059(benD)
PPUH: B479_13460(benD)
PPUT: L483_17645(benD)
PPUN: PP4_25400(benD) PP4_48180(benD)
PPUD: DW66_3021
PMON: X969_13160(benD)
PMOT: X970_12805(benD)
PFL: PFL_3855(xylL)
PPRC: PFLCHA0_c39130(xylL)
PPRO: PPC_3951(benD)
PFE: PSF113_2894(benD)
PFN: HZ99_02920(benD)
PMAN: OU5_6167(xylL)
PAZO: AYR47_21845(benD)
PFX: A7318_13915(benD)
PEN: PSEEN3140(benD)
PPUU: PputUW4_03254(xylL)
PDR: H681_11365(benD)
PSV: PVLB_12230(benD)
PKC: PKB_2103(xylL)
PCH: EY04_20395(benD)
PCP: JM49_10825(benD)
PFZ: AV641_09800(benD)
PLQ: AA042_19050(benD)
PSES: PSCI_4806(benD)
PSEM: TO66_21090(benD)
PPSY: AOC04_06645(benD)
PSOS: POS17_3976(benD)
PFK: PFAS1_22860(benD)
PPSL: BJP27_02335(benD)
PSET: THL1_2895
PSIL: PMA3_10990(benD)
PALL: UYA_06695(benD) UYA_20405(benD)
PGY: AWU82_15480(benD)
PDW: BV82_2263
PSEP: C4K39_5809
PTW: TUM18999_29750(xylL)
PTAE: NCTC10697_02700(benD)
PSA: PST_1670(benD)
PSR: PSTAA_1698(benD)
PSC: A458_09170(benD)
PSJ: PSJM300_08880(benD)
PSTU: UIB01_13630(benD)
PBM: CL52_07430(benD)
AVN: Avin_08620(benD)
AVL: AvCA_08620(benD)
AVD: AvCA6_08620(benD)
ACX: Achr_32810(benD)
MHC: MARHY0281(benD)
MAD: HP15_1108
MPQ: ABA45_01255(benD)
MARI: ACP86_12000(benD)
PSO: PSYCG_06665(benD)
PALI: A3K91_1588
ACB: A1S_1212
ABY: ABAYE2558(benD)
ABN: AB57_1347
ABB: ABBFA_02336(lvr)
ABX: ABK1_1644
ABH: M3Q_1568
ABAD: ABD1_12210(benD)
ABAZ: P795_11430
ABAU: IX87_04590
ABAA: IX88_08130
ACC: BDGL_000463(benD)
ACD: AOLE_13350(benD)
ACI: ACIAD1439(benD)
ASJ: AsACE_CH01477(benD)
AGU: AS4_23700(benD)
AVB: RYU24_15340(benD)
ABOU: ACBO_16050(benD)
AMG: AMEC673_15500(benD)
CYQ: Q91_2245
CZA: CYCME_2563(benD)
HHU: AR456_17680(benD)
HSI: BOX17_05810(benD)
HHH: CLM76_07040(benD)
HBE: BEI_1519
APAC: S7S_13320
MARS: A8C75_10510(benD)
MGEO: CFI10_04840(benD)
OCE: GU3_01775
ZDF: AN401_00165(benD)
PSE: NH8B_1753(benD)
RSC: RCFBP_11859(benD)
RSL: RPSI07_1884(benD)
RPI: Rpic_1367
RMN: TK49_11665(benD)
REH: H16_A1960(benD)
CNC: CNE_1c19300(benD)
CUH: BJN34_08575(benD)
RME: Rmet_4885(benD)
CCUP: BKK81_23220(benD)
CUP: BKK80_33070(benD)
CUU: BKK79_23955(benD)
BMA: BMAA0184
BMV: BMASAVP1_1357(benD)
BML: BMA10229_1552(benD)
BMN: BMA10247_A0212(benD)
BMAL: DM55_3534
BMAE: DM78_4623
BMAQ: DM76_4231
BMAI: DM57_14455(benD)
BMAF: DM51_3935
BMAZ: BM44_3496
BMAB: BM45_4332
BPS: BPSS1906(benD)
BPM: BURPS1710b_A1002(benD)
BPL: BURPS1106A_A2584(benD)
BPD: BURPS668_A2728(benD)
BPSE: BDL_5312
BPSM: BBQ_4224
BPSU: BBN_5371
BPSD: BBX_4477
BPZ: BP1026B_II2045(benD)
BPK: BBK_4645
BPSH: DR55_5828
BPSA: BBU_4103
BPSO: X996_5626
BUT: X994_5189
BTQ: BTQ_3763
BTJ: BTJ_4794
BTZ: BTL_5580
BTD: BTI_5084
BTV: BTHA_4621
BTHE: BTN_5251
BTHM: BTRA_5521
BTHA: DR62_5380(benD)
BTHL: BG87_5596
BOK: DM82_6196
BOC: BG90_4468
BUU: WS70_27015(benD)
BSAV: WS86_28725(benD)
BVE: AK36_5311
BCEN: DM39_5094
BCEW: DM40_5132
BCEO: I35_7537
BAM: Bamb_6581
BMU: Bmul_3241
BMK: DM80_4620
BMUL: NP80_3313
BCED: DM42_7057
BCEP: APZ15_36345(benD)
BDL: AK34_5715
BPYR: ABD05_32070(benD)
BCON: NL30_37450(benD)
BUB: BW23_4425
BDF: WI26_27680(benD)
BLAT: WK25_16340(benD)
BTEI: WS51_27265(benD)
BSEM: WJ12_16745(benD)
BPSL: WS57_00510(benD)
BMEC: WJ16_18210(benD)
BSTG: WT74_22610(benD)
BSTL: BBJ41_36465(benD)
BGO: BM43_5498
BUK: MYA_5341
BUL: BW21_4619
BUD: AQ610_29995(benD)
BUM: AXG89_16415(benD)
BUI: AX768_26125(benD)
BXE: Bxe_B0912(benD)
BXB: DR64_6233
BPH: Bphy_5349
BUZ: AYM40_26005(benD)
PARB: CJU94_35245(benD) CJU94_37920(benD)
PHS: C2L64_29825(benD) C2L64_48515(benD)
PTER: C2L65_18575(benD)
PCJ: CUJ87_08370(benD)
PTS: CUJ90_10080(benD)
PDIO: PDMSB3_2246.1(benD)
CABA: SBC2_79750
BPT: Bpet1396(benD)
BHO: D560_1121
BHM: D558_1108
BTRM: SAMEA390648701944(benD)
ACHR: C2U31_10450(benD)
AFA: UZ73_17880(benD)
AFQ: AFA_08575(benD)
PNA: Pnap_2109
ACRA: BSY15_1216
CSER: CCO03_07070(benD)
HPSE: HPF_01835(lvr)
HSE: Hsero_1311(cbeD)
HSZ: ACP92_06560(benD)
HRB: Hrubri_1137(cbeD)
MASW: AM586_16570(benD)
DAR: Daro_2781
THK: CCZ27_03210(benD) CCZ27_16240(benD)
AMIH: CO731_00666(ydaD)
PHT: BLM14_21520(benD)
SFD: USDA257_c54420(benD)
EAD: OV14_a1474(fabG2)
EAH: FA04_27030(benD)
RHK: Kim5_CH01085(benD)
RSUL: N2599_31260(benD)
XAU: Xaut_4355
MET: M446_1327
MNO: Mnod_2371
MIND: mvi_57260(benD)
RUT: FIU92_22560(novJ)
CEH: CEW89_02920(benD)
CON: TQ29_16490(benD)
SULD: B5M07_19090(benD)
RMM: ROSMUCSMR3_03736(lvr)
ROT: FIV09_19530(ycdF3)
PDE: Pden_1180
PCON: B0A89_14340(benD)
PZH: CX676_12390(benD)
NRE: BES08_19580(benD)
SPHD: HY78_12335(benD)
SPHM: G432_15085(benD)
SECH: B18_24650
SPHR: BSY17_105
SPHT: K426_21224(benD)
SYA: A6768_16780(benD)
BLAS: BSY18_3981
BFW: B5J99_00990(benD)
ALB: AEB_P2434
RGI: RGI145_20865(benD)
AZL: AZL_a07370(benD)
MMAT: MMAGJ_52720(benD)
CGL: Cgl2407(Cgl2407)
CGB: cg2640(benD)
CGU: WA5_2323(BenD)
CGT: cgR_2288
CGS: C624_11685(benD)
CGG: C629_11695(benD)
CGM: cgp_2640(benD)
CGJ: AR0_11525(benD)
CGQ: CGLAR1_11375(benD)
CGX: SB89_11180(benD)
CEF: CE2308
CHN: A605_11140(benD)
CCN: H924_10135(benD)
CMD: B841_10265(benD)
CII: CIMIT_11045(benD)
CMQ: B840_09755(xylL)
CDX: CDES_10945(benD)
CSTA: CSTAT_12750(benD)
CCJZ: ccrud_10715(benD)
CAMG: CAMM_12485(benD)
CSUR: N24_2477(benD)
CCYS: SAMEA4530656_0415(benD)
CCOE: CETAM_10400(lvr)
COK: COCCU_10780(lvr2)
CCYC: SCMU_25440(benD)
BFV: C628_11665(benD)
RHA: RHA1_ro02387(benD)
RQI: C1M55_27410(benD)
ROP: ROP_21010(benD)
RPY: Y013_13600(benD)
RBY: CEJ39_00980(benD)
RAV: AAT18_24450(benD)
RRZ: CS378_14030(benD)
RHQ: IM25_04945(benD)
RHOD: AOT96_07380(benD)
RRT: 4535765_04644(benD)
RCR: NCTC10994_02858(benD)
ROZ: CBI38_27130(benD)
DPC: A6048_05505(benD)
DLU: A6035_05570(benD)
STSU: B7R87_02845(benD)
ARU: ASPU41_14625(benD)
ARN: CGK93_10510(benD)
ACRY: AC20117_04985(benD)
PSUL: AU252_22710(benD)
KPL: KPaMU14_10935(benD)
KFV: AS188_00025(benD)
SHT: KO02_15975(benD)
CSAL: NBC122_01822(ycdF)
 » show all
Reference
PMID:1740120
  Authors
Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S
  Title
cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.
  Journal
Eur J Biochem 204:113-20 (1992)
DOI:10.1111/j.1432-1033.1992.tb16612.x
  Sequence
[aci:ACIAD1439]

KEGG   ENZYME: 1.3.1.25
Entry
EC 1.3.1.25                 Enzyme                                 
Name
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase;
dihydrodihydroxybenzoate dehydrogenase;
DHBDH;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase;
2-hydro-1,2-dihydroxybenzoate dehydrogenase;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase;
dihydrodihydroxybenzoate dehydrogenase;
(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
Reaction(IUBMB)
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+ [RN:R00813]
Reaction(KEGG)
R00813;
(other) R08111 R08112 R08113
Substrate
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate [CPD:C06321];
NAD+ [CPD:C00003]
Product
catechol [CPD:C00090];
CO2 [CPD:C00011];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.3.1.25 created 1976, modified 2004 (EC 1.3.1.55 created 1999, incorporated 2004)
Pathway
ec00362  Benzoate degradation
ec00364  Fluorobenzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05783  dihydroxycyclohexadiene carboxylate dehydrogenase
Genes
EFEEFER_1485(benD)
KPNKPN_01869
KPUKP1_2934
KPMKPHS_28390
KPPA79E_2376
KPHKPNIH24_14210(benD)
KPZKPNIH27_13570(benD)
KPVKPNIH29_14240(benD)
KPWKPNIH30_14505(benD)
KPYKPNIH31_13520(benD)
KPGKPNIH32_14400(benD)
KPCKPNIH10_14040(benD)
KPQKPR0928_14020(benD)
KPTVK055_0615
KPOKPN2242_12265(benD)
KPRKPR_2933(benD)
KPJN559_2421
KPID364_09585(benD)
KPAKPNJ1_02608
KPSKPNJ2_02563
KPXPMK1_04210(lvr)
KPBFH42_05420(benD)
KPNEKU54_012115(benD)
KPNULI86_12050(benD)
KPNKBN49_2969(benD)
KVAKvar_2435
KPEKPK_2488(cbeD)
KPKA593_24210(benD)
KVDKR75_22145(benD)
KVQSP68_02890(benD)
KOCAB185_22235(benD)
KQUAVR78_18380(benD)
EAEEAE_19880(benD)
EARCCG29904
KQVB8P98_13160(benD)
KARLGL98_11655
KGRJJJ10_14635
RORRORB6_06755(benD)
RONTE10_13830(benD)
RPLNB1209_13860(benD)
RAODSD31_13375
RTGNCTC13098_03815(lvr_2)
CSEDJY391_11115
CAFAL524_15085
CFARCI104_13175(benD)
CIRC2U53_22220(benD)
CTELGBC03_17315
EBTEBL_c18160
PGELG71_16210(benD)
BUFD8682_03275
IZHFEM41_18110
PSGCG163CM_11650(lvr)
EBFD782_2133
EBUCUC76_01775(benD)
SMWSMWW4_v1c30600
SMAFD781_2850
SRZAXX16_2219
SERMCLM71_14595(benD)
SFJSAMEA4384070_3090(xecD)
SSURATE40_011850(benD)
SRHZFO014_19065
SENPKHA73_15020
RBADH2866_19745
XSASB85_10140(benD)
PSDDSC_14910(benD)
VNAPN96_18365(benD)
VEJVEJY3_17926(benD)
VJPNP165_16980(benD)
PAEPA2515(xylL)
PAEVN297_2586
PAEIN296_2586
PAUPA14_32130(xylL)
PAPPSPA7_2722(xylL)
PAGPLES_27801(xylL)
PAFPAM18_2524(benD)
PNCNCGM2_3520(benD)
PAEBNCGM1900_4012(benD)
PDKPADK2_12670(benD)
PSGG655_12450(benD)
PRPM062_13075(benD)
PAEPPA1S_13070(benD)
PAERPA1R_gp0309
PAEMU769_12650(benD)
PAELT223_14270(benD)
PAESSCV20265_2794
PAEUBN889_02739(benD)
PAEGAI22_20850(benD)
PAECM802_2583
PAEOM801_2451
PMKMDS_4167
PREPCA10_30910(benD)
PPSEBN5_3608(benD)
PFUWKF707C_15520(bzaB) KF707C_28440
PCQPcP3B5_23360(lvr)
PPUPP_3164(benD)
PPFPput_2551
PPGPputGB1_2685
PPWPputW619_2707
PPTPPS_2762
PPBPPUBIRD1_2569(benD)
PPIYSA_10652
PPXT1E_1059(benD)
PPUHB479_13460(benD)
PPUTL483_17645(benD)
PPUNPP4_25400(benD) PP4_48180(benD)
PPUDDW66_3021
PFVPsefu_2026
PMONX969_13160(benD)
PMOTX970_12805(benD)
PPJRK21_01914
PFLPFL_3855(xylL)
PPRCPFLCHA0_c39130(xylL)
PPROPPC_3951(benD)
PFEPSF113_2894(benD)
PFNHZ99_02920(benD)
PFOPfl01_2324 Pfl01_2965(benD)
PMANOU5_6167(xylL)
PAZOAYR47_21845(benD)
PFXA7318_13915(benD)
PENPSEEN3140(benD)
PLULFOB45_00445
PBAPSEBR_a2882
PPUUPputUW4_03254(xylL)
PDRH681_11365(benD)
PSVPVLB_12230(benD)
PKCPKB_2103(xylL)
PCHEY04_20395(benD)
PCZPCL1606_21670
PCPJM49_10825(benD)
PFZAV641_09800(benD)
PLQAA042_19050(benD)
PALKPSAKL28_52390
PSESPSCI_4806(benD)
PSEMTO66_21090(benD)
PPSYAOC04_06645(benD)
PSOSPOS17_3976(benD)
PFKPFAS1_22860(benD)
PPSLBJP27_02335(benD)
PSETTHL1_2895
PSILPMA3_10990(benD)
PYMAK972_2990
PALLUYA_06695(benD) UYA_20405(benD)
PUMHGP31_18590
PPSHG5J76_17155
PGYAWU82_15480(benD)
PLALFXN65_12620
PEZHWQ56_13965
PDWBV82_2263
PZEHU754_016970
PSEPC4K39_5809
PTZHU718_017520
PSHHHU773_013520
PANHHU763_012295
PAZEKSS91_10650
PORYEJA05_13820
PWZJ7655_17885
PTKEXN22_01370
PTWTUM18999_29750(xylL)
PTAENCTC10697_02700(benD)
PGFJ0G10_14060
PCAVD3880_08570
PJUL1P09_13265
PPHNHU825_11445
PIZLAB08_R37340
PSIHLOY51_13760
PSAPST_1670(benD)
PSRPSTAA_1698(benD)
PSCA458_09170(benD)
PSJPSJM300_08880(benD)
PSHPsest_2696
PSTUUIB01_13630(benD)
PSEDDM292_11225
PCHLLLJ08_12930
PBMCL52_07430(benD)
PKGLW136_09530
SDEGGOM96_16690
AVNAvin_08620(benD)
AVLAvCA_08620(benD)
AVDAvCA6_08620(benD)
ACXAchr_32810(benD)
HPEGEAO82_00580
MHCMARHY0281(benD)
MADHP15_1108
MPQABA45_01255(benD)
MARIACP86_12000(benD)
PCRPcryo_1264
PSOPSYCG_06665(benD)
PALIA3K91_1588
PSPGAK823_04985
PSYGAK825_05000
PSYPE5677_05445
ACBA1S_1212
ABYABAYE2558(benD)
ABCACICU_01189
ABNAB57_1347
ABBABBFA_02336(lvr)
ABXABK1_1644
ABZABZJ_01348
ABRABTJ_02517
ABDABTW07_1376
ABHM3Q_1568
ABADABD1_12210(benD)
ABJBJAB07104_01359
ABABBJAB0715_01371
ABAJBJAB0868_01307
ABAZP795_11430
ABKLX00_05835
ABAUIX87_04590
ABAAIX88_08130
ABWBL01_13775
ABALABLAC_20300
ACCBDGL_000463(benD)
ANORR32_12270
ALCOTEC02_13000
ACALBUM88_05780
ASEII8T81_13015
ACDAOLE_13350(benD)
ACIACIAD1439(benD)
ATTAMQ28_00600
AEIAOY20_11285
AJORZ95_08915
ACWA0J50_11650
ACVAMD27_07845
AJNBVL33_09975
ASOLBEN76_06765
ASJAsACE_CH01477(benD)
AIDCTZ23_07100
ADVDJ533_10820
ARJDOM24_07535
AWUBEN71_06045
ACUMC9E88_012210
AGUAS4_23700(benD)
ALWFOB21_01940
ADSFPL17_10305
ABERBSR55_11570
ATNFM020_08965
ALJG8D99_08475
ATGJ4G44_08925
AVBRYU24_15340(benD)
ABOUACBO_16050(benD)
AGYLFPL18_02705
AVZHWI77_08295
MOIMOVS_09455
AMGAMEC673_15500(benD)
ALRDS731_05535
CYQQ91_2245
CZACYCME_2563(benD)
CYYCPC19_01575
HAKKO116_00235
HHUAR456_17680(benD)
HSIBOX17_05810(benD)
HHHCLM76_07040(benD)
HBEBEI_1519
HCAMI4484_18800
HPIZGYM47_16275
HPROLMS44_22930
APACS7S_13320
MMEMarme_1558
MARSA8C75_10510(benD)
MGEOCFI10_04840(benD)
MSECLN244_11355
ASIMFE240_08800
OCEGU3_01775
ZDFAN401_00165(benD)
GBIPG2T_09665
VMSLVJ82_06055
USULVJ78_07365
UTELVJ83_07960
PSENH8B_1753(benD)
RSCRCFBP_11859(benD)
RSLRPSI07_1884(benD)
RSNRSPO_c01859
RSYRSUY_19290
RPIRpic_1367
RPFRpic12D_1431
RPJN234_27840 N234_37270(benD)
RMNTK49_11665(benD)
RINACS15_1754
RSGJK151_11745
REHH16_A1960(benD)
CNCCNE_1c19300(benD)
CUHBJN34_08575(benD)
REUReut_B4406
RMERmet_4885(benD)
CBWRR42_s0554
CCUPBKK81_23220(benD)
CUPBKK80_33070(benD)
CUUBKK79_23955(benD)
CPAUEHF44_23095
COXE0W60_20505 E0W60_32235
BMABMAA0184
BMVBMASAVP1_1357(benD)
BMLBMA10229_1552(benD)
BMNBMA10247_A0212(benD)
BMALDM55_3534
BMAEDM78_4623
BMAQDM76_4231
BMAIDM57_14455(benD)
BMAFDM51_3935
BMAZBM44_3496
BMABBM45_4332
BPSBPSS1906(benD)
BPMBURPS1710b_A1002(benD)
BPLBURPS1106A_A2584(benD)
BPDBURPS668_A2728(benD)
BPSEBDL_5312
BPSMBBQ_4224
BPSUBBN_5371
BPSDBBX_4477
BPZBP1026B_II2045(benD)
BPQBPC006_II2547
BPKBBK_4645
BPSHDR55_5828
BPSABBU_4103
BPSOX996_5626
BUTX994_5189
BTEBTH_II0470
BTQBTQ_3763
BTJBTJ_4794
BTZBTL_5580
BTDBTI_5084
BTVBTHA_4621
BTHEBTN_5251
BTHMBTRA_5521
BTHADR62_5380(benD)
BTHLBG87_5596
BOKDM82_6196
BOCBG90_4468
BUUWS70_27015(benD)
BSAVWS86_28725(benD)
BHGI6G56_27550
BVIBcep1808_5828
BVEAK36_5311
BURBcep18194_C7049
BCMBcenmc03_6134
BCHBcen2424_6527
BCENDM39_5094
BCEWDM40_5132
BCEOI35_7537
BAMBamb_6581
BACBamMC406_6296
BMUBmul_3241
BMKDM80_4620
BMULNP80_3313
BCEDDM42_7057
BCEPAPZ15_36345(benD)
BDLAK34_5715
BPYRABD05_32070(benD)
BCONNL30_37450(benD)
BUBBW23_4425
BDFWI26_27680(benD)
BLATWK25_16340(benD)
BTEIWS51_27265(benD)
BSEMWJ12_16745(benD)
BPSLWS57_00510(benD)
BMECWJ16_18210(benD)
BSTGWT74_22610(benD)
BSTLBBJ41_36465(benD)
BUGBC1001_1344
BGOBM43_5498
BYIBYI23_D002180
BUKMYA_5341
BUEBRPE67_DCDS03930
BULBW21_4619
BUQAC233_11160
BUDAQ610_29995(benD)
BUMAXG89_16415(benD)
BUIAX768_26125(benD)
BURKDM992_37910
BXEBxe_B0912(benD)
BXBDR64_6233
BPHBphy_5349
BGEBC1002_6177
BPXBUPH_01851
BPYBphyt_1594
BUZAYM40_26005(benD)
BCAIK788_0005752
PSPWBJG93_32100
PARBCJU94_35245(benD) CJU94_37920(benD)
PHSC2L64_29825(benD) C2L64_48515(benD)
PTERC2L65_18575(benD)
PCJCUJ87_08370(benD)
PTSCUJ90_10080(benD)
PCAFDSC91_002403
PTROG5S35_36180
PGISI6I06_20450 I6I06_20465
PACPFAZ97_31360
PACSFAZ98_17695
PDIOPDMSB3_2246.1(benD)
CABASBC2_79750
BUOBRPE64_DCDS08510
BPTBpet1396(benD)
BHOD560_1121
BHMD558_1108
BTRMSAMEA390648701944(benD)
AXYAXYL_01800
AISBUW96_17365
ACHRC2U31_10450(benD)
ACHBDVB37_15210
ACHOH4P35_21825
AFAUZ73_17880(benD)
AFQAFA_08575(benD)
AAQUD3M96_09795
AAMMFE795_07790
OURCEQ07_11095
OUEI6G29_07010
PNAPnap_2109
ACRABSY15_1216
CSERCCO03_07070(benD)
CODOLAD35_11955
ADNAlide_2649
HPSEHPF_01835(lvr)
DIHG7047_12820
SIMPC6571_19145
JAJEKL02_16455
JASFJQ89_23180
HSEHsero_1311(cbeD)
HSZACP92_06560(benD)
HRBHrubri_1137(cbeD)
HHFE2K99_06475
HFRG5S34_06740
MASWAM586_16570(benD)
MALIEYF70_17200
MUMFCL38_01220
GLCJQN73_16180
AONDEH84_15075
RBUPG1C_04535
DARDaro_2781
DDENKI615_11390
TMZTmz1t_3099
THKCCZ27_03210(benD) CCZ27_16240(benD)
AMIHCO731_00666(ydaD)
PHTBLM14_21520(benD)
SFHSFHH103_03581
SFDUSDA257_c54420(benD)
SINOSS05631_c27060
EADOV14_a1474(fabG2)
EAHFA04_27030(benD)
ESJSJ05684_b58660
EAKEKH55_4347
ARAArad_12206
RHKKim5_CH01085(benD)
RSULN2599_31260(benD)
BBETF8237_17750
BOSBSY19_2041
XAUXaut_4355
XDIEZH22_09305
LNEFZC33_07195
METM446_1327
MNOMnod_2371
MEEDA075_16970
MTEADK419_08715
MINDmvi_57260(benD)
RHZRHPLAN_59320
RUTFIU92_22560(novJ)
CMARIMCC12053_2583
CEHCEW89_02920(benD)
CONTQ29_16490(benD)
SULDB5M07_19090(benD)
RMMROSMUCSMR3_03736(lvr)
ROKRAK1035_2575
ROTFIV09_19530(ycdF3)
PDEPden_1180
PCONB0A89_14340(benD)
PZHCX676_12390(benD)
PPANESD82_01805
PSANHGN31_00295
TECAKL02_003795
NARSaro_0540 Saro_3837
NPPPP1Y_AT15839 PP1Y_AT31260
NPNJI59_24685
NREBES08_19580(benD)
NOGGKE62_05255
NDRHT578_08795
SWISwit_2636 Swit_5024
SPHDHY78_12335(benD)
SPHMG432_15085(benD)
SECHB18_24650
SPHRBSY17_105
SPHTK426_21224(benD)
SYAA6768_16780(benD)
SBARH5V43_22415
SPHYCHN51_07050
BLASBSY18_3981
BFWB5J99_00990(benD)
ALBAEB_P2434
CNAAB433_18075
ERYCP97_14260
RGIRGI145_20865(benD)
RMUCFOB66_02980
AZLAZL_a07370(benD)
AZMDM194_25860
SMUCJL100_027665
SROEJL101_026020
PARHI5S86_15030
MMATMMAGJ_52720(benD)
CGLCgl2407(Cgl2407)
CGBcg2640(benD)
CGUWA5_2323(BenD)
CGTcgR_2288
CGSC624_11685(benD)
CGGC629_11695(benD)
CGMcgp_2640(benD)
CGJAR0_11525(benD)
CGQCGLAR1_11375(benD)
CGXSB89_11180(benD)
CEFCE2308
CHNA605_11140(benD)
CCNH924_10135(benD)
CMDB841_10265(benD)
CIICIMIT_11045(benD)
CMQB840_09755(xylL)
CDXCDES_10945(benD)
CSTACSTAT_12750(benD)
CCJZccrud_10715(benD)
CAMGCAMM_12485(benD)
CSURN24_2477(benD)
CCYSSAMEA4530656_0415(benD)
CYZC3B44_09185
CCOECETAM_10400(lvr)
COKCOCCU_10780(lvr2)
CCYCSCMU_25440(benD)
CPOYGP475_09410
BFVC628_11665(benD)
RHARHA1_ro02387(benD)
RQIC1M55_27410(benD)
ROPROP_21010(benD)
ROAPd630_LPD06583
RPYY013_13600(benD)
RBYCEJ39_00980(benD)
RAVAAT18_24450(benD)
RRZCS378_14030(benD)
RHQIM25_04945(benD)
RHODAOT96_07380(benD)
RRT4535765_04644(benD)
RCRNCTC10994_02858(benD)
RKOJWS14_12420
ROZCBI38_27130(benD)
RPSKJWS13_33420
DTMBJL86_1202
DPCA6048_05505(benD)
DLUA6035_05570(benD)
DKNNHB83_05170
SQZFQU76_02750
STSUB7R87_02845(benD)
ARUASPU41_14625(benD)
ARNCGK93_10510(benD)
ACRYAC20117_04985(benD)
ARTPE5206_02265
APNAsphe3_35130
PSULAU252_22710(benD)
PSNINIBR502771_06640
PSEYGU243_07215
GLUF0M17_16120
KPLKPaMU14_10935(benD)
KFVAS188_00025(benD)
KRSEQG70_04345
SATKSA2016_0099
CIGE7744_08330
PAEYKUF55_15625
SVISvir_19240
SHTKO02_15975(benD)
FSEDI487_06970
CSALNBC122_01822(ycdF)
 » show all
Reference
1  [PMID:4341530]
  Authors
Reiner AM.
  Title
Metabolism of aromatic compounds in bacteria. Purification and properties of the catechol-forming enzyme, 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid (NAD + ) oxidoreductase (decarboxylating).
  Journal
J Biol Chem 247:4960-5 (1972)
Reference
2  [PMID:1740120]
  Authors
Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S
  Title
cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.
  Journal
Eur J Biochem 204:113-20 (1992)
DOI:10.1111/j.1432-1033.1992.tb16612.x
  Sequence
[aci:ACIAD1439]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.25
IUBMB Enzyme Nomenclature: 1.3.1.25
ExPASy - ENZYME nomenclature database: 1.3.1.25
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.25
BRENDA, the Enzyme Database: 1.3.1.25
CAS: 60496-16-4

KEGG   REACTION: R00813
Entry
R00813                      Reaction                               
Name
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
Definition
(1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ <=> Catechol + NADH + CO2 + H+
Equation
Comment
BenD
Reaction class
RC00001  C00003_C00004
RC00271  C00090_C06321
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
Orthology
K05783  dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]
Other DBs
RHEA: 11563

DBGET integrated database retrieval system