KEGG   ORTHOLOGY: K05783
Entry
K05783                      KO                                     
Symbol
benD-xylL
Name
dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]
Pathway
map00362  Benzoate degradation
map00364  Fluorobenzoate degradation
map00622  Xylene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
   00364 Fluorobenzoate degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
   00622 Xylene degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.25  1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
     K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
    1.3.1.-
     K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K05783
Other DBs
RN: R00813 R05292 R05293 R05309 R05314 R08111 R08112 R08113
COG: COG1028
GO: 0047116
Genes
EFE: EFER_1485(benD)
KPN: KPN_01869
KPU: KP1_2934
KPM: KPHS_28390
KPP: A79E_2376
KPH: KPNIH24_14210(benD)
KPZ: KPNIH27_13570(benD)
KPV: KPNIH29_14240(benD)
KPW: KPNIH30_14505(benD)
KPY: KPNIH31_13520(benD)
KPG: KPNIH32_14400(benD)
KPC: KPNIH10_14040(benD)
KPQ: KPR0928_14020(benD)
KPT: VK055_0615
KPO: KPN2242_12265(benD)
KPR: KPR_2933(benD)
KPJ: N559_2421
KPI: D364_09585(benD)
KPA: KPNJ1_02608
KPS: KPNJ2_02563
KPX: PMK1_04210(lvr)
KPB: FH42_05420(benD)
KPNE: KU54_012115(benD)
KPNU: LI86_12050(benD)
KPNK: BN49_2969(benD)
KVA: Kvar_2435
KPE: KPK_2488(cbeD)
KPK: A593_24210(benD)
KVD: KR75_22145(benD)
KVQ: SP68_02890(benD)
KOC: AB185_22235(benD)
KQU: AVR78_18380(benD)
EAE: EAE_19880(benD)
EAR: CCG29904
KQV: B8P98_13160(benD)
KAR: LGL98_11655
KGR: JJJ10_14635
ROR: RORB6_06755(benD)
RON: TE10_13830(benD)
RPLN: B1209_13860(benD)
RAO: DSD31_13375
RTG: NCTC13098_03815(lvr_2)
CSED: JY391_11115
CAF: AL524_15085
CFAR: CI104_13175(benD)
CIR: C2U53_22220(benD)
CTEL: GBC03_17315
EBT: EBL_c18160
PGE: LG71_16210(benD)
BUF: D8682_03275
IZH: FEM41_18110
PSGC: G163CM_11650(lvr)
EBF: D782_2133
EBU: CUC76_01775(benD)
SMW: SMWW4_v1c30600
SMAF: D781_2850
SRZ: AXX16_2219
SERM: CLM71_14595(benD)
SFJ: SAMEA4384070_3090(xecD)
SSUR: ATE40_011850(benD)
SRHZ: FO014_19065
SENP: KHA73_15020
SNEM: NLX84_15360(benD)
RBAD: H2866_19745
XSA: SB85_10140(benD)
PSD: DSC_14910(benD)
VNA: PN96_18365(benD)
VEJ: VEJY3_17926(benD)
VJP: NP165_16980(benD)
PAE: PA2515(xylL)
PAEV: N297_2586
PAEI: N296_2586
PAU: PA14_32130(xylL)
PAP: PSPA7_2722(xylL)
PAG: PLES_27801(xylL)
PAF: PAM18_2524(benD)
PNC: NCGM2_3520(benD)
PAEB: NCGM1900_4012(benD)
PDK: PADK2_12670(benD)
PSG: G655_12450(benD)
PRP: M062_13075(benD)
PAEP: PA1S_13070(benD)
PAER: PA1R_gp0309
PAEM: U769_12650(benD)
PAEL: T223_14270(benD)
PAES: SCV20265_2794
PAEU: BN889_02739(benD)
PAEG: AI22_20850(benD)
PAEC: M802_2583
PAEO: M801_2451
PMK: MDS_4167
PRE: PCA10_30910(benD)
PPSE: BN5_3608(benD)
PFUW: KF707C_15520(bzaB) KF707C_28440
PCQ: PcP3B5_23360(lvr)
PPAA: B7D75_12600
PPU: PP_3164(benD)
PPF: Pput_2551
PPG: PputGB1_2685
PPW: PputW619_2707
PPT: PPS_2762
PPB: PPUBIRD1_2569(benD)
PPI: YSA_10652
PPX: T1E_1059(benD)
PPUH: B479_13460(benD)
PPUT: L483_17645(benD)
PPUN: PP4_25400(benD) PP4_48180(benD)
PPUD: DW66_3021
PFV: Psefu_2026
PMON: X969_13160(benD)
PMOT: X970_12805(benD)
PPJ: RK21_01914
PFL: PFL_3855(xylL)
PPRC: PFLCHA0_c39130(xylL)
PPRO: PPC_3951(benD)
PFE: PSF113_2894(benD)
PFN: HZ99_02920(benD)
PFO: Pfl01_2324 Pfl01_2965(benD)
PMAN: OU5_6167(xylL)
PAZO: AYR47_21845(benD)
PFX: A7318_13915(benD)
PEN: PSEEN3140(benD)
PLUL: FOB45_00445
PBA: PSEBR_a2882
PPUU: PputUW4_03254(xylL)
PDR: H681_11365(benD)
PSV: PVLB_12230(benD)
PKC: PKB_2103(xylL)
PCH: EY04_20395(benD)
PCZ: PCL1606_21670
PCP: JM49_10825(benD)
PFZ: AV641_09800(benD)
PLQ: AA042_19050(benD)
PALK: PSAKL28_52390
PSES: PSCI_4806(benD)
PSEM: TO66_21090(benD)
PPSY: AOC04_06645(benD)
PSOS: POS17_3976(benD)
PFK: PFAS1_22860(benD)
PPSL: BJP27_02335(benD)
PSET: THL1_2895
PSIL: PMA3_10990(benD)
PYM: AK972_2990
PALL: UYA_06695(benD) UYA_20405(benD)
PUM: HGP31_18590
PPSH: G5J76_17155
PGY: AWU82_15480(benD)
PLAL: FXN65_12620
PEZ: HWQ56_13965
PDW: BV82_2263
PZE: HU754_016970
PSEP: C4K39_5809
PTZ: HU718_017520
PSHH: HU773_013520
PANH: HU763_012295
PAZE: KSS91_10650
PORY: EJA05_13820
PWZ: J7655_17885
PTK: EXN22_01370
PTW: TUM18999_29750(xylL)
PTAE: NCTC10697_02700(benD)
PGF: J0G10_14060
PCAV: D3880_08570
PJU: L1P09_13265
PPHN: HU825_11445
PIZ: LAB08_R37340
PSIH: LOY51_13760
PFIT: KJY40_13375
PSA: PST_1670(benD)
PSR: PSTAA_1698(benD)
PSC: A458_09170(benD)
PSJ: PSJM300_08880(benD)
PSH: Psest_2696
PSTU: UIB01_13630(benD)
PSED: DM292_11225
PCHL: LLJ08_12930
PBM: CL52_07430(benD)
PKG: LW136_09530
SDEG: GOM96_16690
AVN: Avin_08620(benD)
AVL: AvCA_08620(benD)
AVD: AvCA6_08620(benD)
ACX: Achr_32810(benD)
HPEG: EAO82_00580
PBAU: OS670_01855
MHC: MARHY0281(benD)
MAD: HP15_1108
MPQ: ABA45_01255(benD)
MARI: ACP86_12000(benD)
PCR: Pcryo_1264
PSO: PSYCG_06665(benD)
PALI: A3K91_1588
PSPG: AK823_04985
PSYG: AK825_05000
PSYP: E5677_05445
ACB: A1S_1212
ABY: ABAYE2558(benD)
ABC: ACICU_01189
ABN: AB57_1347
ABB: ABBFA_02336(lvr)
ABX: ABK1_1644
ABZ: ABZJ_01348
ABR: ABTJ_02517
ABD: ABTW07_1376
ABH: M3Q_1568
ABAD: ABD1_12210(benD)
ABJ: BJAB07104_01359
ABAB: BJAB0715_01371
ABAJ: BJAB0868_01307
ABAZ: P795_11430
ABK: LX00_05835
ABAU: IX87_04590
ABAA: IX88_08130
ABW: BL01_13775
ABAL: ABLAC_20300
ACC: BDGL_000463(benD)
ANO: RR32_12270
ALC: OTEC02_13000
ACAL: BUM88_05780
ASEI: I8T81_13015
ACD: AOLE_13350(benD)
ACI: ACIAD1439(benD)
ATT: AMQ28_00600
AEI: AOY20_11285
AJO: RZ95_08915
ACW: A0J50_11650
ACV: AMD27_07845
AJN: BVL33_09975
ASOL: BEN76_06765
ASJ: AsACE_CH01477(benD)
AID: CTZ23_07100
ADV: DJ533_10820
ARJ: DOM24_07535
AWU: BEN71_06045
ACUM: C9E88_012210
AGU: AS4_23700(benD)
ALW: FOB21_01940
ADS: FPL17_10305
ABER: BSR55_11570
ATN: FM020_08965
ALJ: G8D99_08475
ATG: J4G44_08925
AVB: RYU24_15340(benD)
ABOU: ACBO_16050(benD)
AGYL: FPL18_02705
AVZ: HWI77_08295
MOI: MOVS_09455
AMG: AMEC673_15500(benD)
ALR: DS731_05535
CYQ: Q91_2245
CZA: CYCME_2563(benD)
CYY: CPC19_01575
HAK: KO116_00235
HHU: AR456_17680(benD)
HSI: BOX17_05810(benD)
HHH: CLM76_07040(benD)
HBE: BEI_1519
HCAM: I4484_18800
HPIZ: GYM47_16275
HPRO: LMS44_22930
HQD: K1Y77_14475
APAC: S7S_13320
MME: Marme_1558
MARS: A8C75_10510(benD)
MGEO: CFI10_04840(benD)
MSEC: LN244_11355
MRZ: KDW95_03785
ASIM: FE240_08800
OCE: GU3_01775
ZDF: AN401_00165(benD)
GBI: PG2T_09665
VMS: LVJ82_06055
USU: LVJ78_07365
UTE: LVJ83_07960
PSE: NH8B_1753(benD)
RSC: RCFBP_11859(benD)
RSL: RPSI07_1884(benD)
RSN: RSPO_c01859
RSY: RSUY_19290
RPI: Rpic_1367
RPF: Rpic12D_1431
RPJ: N234_27840 N234_37270(benD)
RMN: TK49_11665(benD)
RIN: ACS15_1754
RSG: JK151_11745
RWE: KOL96_15110
REH: H16_A1960(benD)
CNC: CNE_1c19300(benD)
CUH: BJN34_08575(benD)
REU: Reut_B4406
RME: Rmet_4885(benD)
CBW: RR42_s0554
CCUP: BKK81_23220(benD)
CUP: BKK80_33070(benD)
CUU: BKK79_23955(benD)
CPAU: EHF44_23095
COX: E0W60_20505 E0W60_32235
BMA: BMAA0184
BMV: BMASAVP1_1357(benD)
BML: BMA10229_1552(benD)
BMN: BMA10247_A0212(benD)
BMAL: DM55_3534
BMAE: DM78_4623
BMAQ: DM76_4231
BMAI: DM57_14455(benD)
BMAF: DM51_3935
BMAZ: BM44_3496
BMAB: BM45_4332
BPS: BPSS1906(benD)
BPM: BURPS1710b_A1002(benD)
BPL: BURPS1106A_A2584(benD)
BPD: BURPS668_A2728(benD)
BPSE: BDL_5312
BPSM: BBQ_4224
BPSU: BBN_5371
BPSD: BBX_4477
BPZ: BP1026B_II2045(benD)
BPQ: BPC006_II2547
BPK: BBK_4645
BPSH: DR55_5828
BPSA: BBU_4103
BPSO: X996_5626
BUT: X994_5189
BTE: BTH_II0470
BTQ: BTQ_3763
BTJ: BTJ_4794
BTZ: BTL_5580
BTD: BTI_5084
BTV: BTHA_4621
BTHE: BTN_5251
BTHM: BTRA_5521
BTHA: DR62_5380(benD)
BTHL: BG87_5596
BOK: DM82_6196
BOC: BG90_4468
BUU: WS70_27015(benD)
BSAV: WS86_28725(benD)
BHG: I6G56_27550
BVI: Bcep1808_5828
BVE: AK36_5311
BUR: Bcep18194_C7049
BCM: Bcenmc03_6134
BCH: Bcen2424_6527
BCEN: DM39_5094
BCEW: DM40_5132
BCEO: I35_7537
BAM: Bamb_6581
BAC: BamMC406_6296
BMU: Bmul_3241
BMK: DM80_4620
BMUL: NP80_3313
BCED: DM42_7057
BCEP: APZ15_36345(benD)
BDL: AK34_5715
BPYR: ABD05_32070(benD)
BCON: NL30_37450(benD)
BUB: BW23_4425
BDF: WI26_27680(benD)
BLAT: WK25_16340(benD)
BTEI: WS51_27265(benD)
BSEM: WJ12_16745(benD)
BPSL: WS57_00510(benD)
BMEC: WJ16_18210(benD)
BSTG: WT74_22610(benD)
BSTL: BBJ41_36465(benD)
BARI: NLX30_38100(benD)
BUG: BC1001_1344
BGO: BM43_5498
BYI: BYI23_D002180
BUK: MYA_5341
BUE: BRPE67_DCDS03930
BUL: BW21_4619
BUQ: AC233_11160
BUD: AQ610_29995(benD)
BUM: AXG89_16415(benD)
BUI: AX768_26125(benD)
BURK: DM992_37910
BXE: Bxe_B0912(benD)
BXB: DR64_6233
BPH: Bphy_5349
BGE: BC1002_6177
BPX: BUPH_01851
BPY: Bphyt_1594
BUZ: AYM40_26005(benD)
BCAI: K788_0005752
PSPW: BJG93_32100
PARB: CJU94_35245(benD) CJU94_37920(benD)
PHS: C2L64_29825(benD) C2L64_48515(benD)
PTER: C2L65_18575(benD)
PCJ: CUJ87_08370(benD)
PTS: CUJ90_10080(benD)
PCAF: DSC91_002403
PTRO: G5S35_36180
PGIS: I6I06_20450 I6I06_20465
PACP: FAZ97_31360
PACS: FAZ98_17695
PDIO: PDMSB3_2246.1(benD)
CABA: SBC2_79750
BUO: BRPE64_DCDS08510
BPT: Bpet1396(benD)
BHO: D560_1121
BHM: D558_1108
BTRM: SAMEA390648701944(benD)
AXY: AXYL_01800
AIS: BUW96_17365
ACHR: C2U31_10450(benD)
ACHB: DVB37_15210
ACHO: H4P35_21825
AFA: UZ73_17880(benD)
AFQ: AFA_08575(benD)
AAQU: D3M96_09795
AAMM: FE795_07790
OUR: CEQ07_11095
OUE: I6G29_07010
PNA: Pnap_2109
ACRA: BSY15_1216
CSER: CCO03_07070(benD)
CODO: LAD35_11955
ADN: Alide_2649
HPSE: HPF_01835(lvr)
DIH: G7047_12820
SIMP: C6571_19145
JAJ: EKL02_16455
JAS: FJQ89_23180
HSE: Hsero_1311(cbeD)
HSZ: ACP92_06560(benD)
HRB: Hrubri_1137(cbeD)
HHF: E2K99_06475
HFR: G5S34_06740
MASW: AM586_16570(benD)
MALI: EYF70_17200
MUM: FCL38_01220
GLC: JQN73_16180
AON: DEH84_15075
RBU: PG1C_04535
DAR: Daro_2781
DDEN: KI615_11390
TMZ: Tmz1t_3099
THK: CCZ27_03210(benD) CCZ27_16240(benD)
AMIH: CO731_00666(ydaD)
PHT: BLM14_21520(benD)
SFH: SFHH103_03581
SFD: USDA257_c54420(benD)
SINO: SS05631_c27060
EAD: OV14_a1474(fabG2)
EAH: FA04_27030(benD)
ESJ: SJ05684_b58660
EAK: EKH55_4347
ARA: Arad_12206
RHK: Kim5_CH01085(benD)
RSUL: N2599_31260(benD)
BBET: F8237_17750
BOS: BSY19_2041
XAU: Xaut_4355
XDI: EZH22_09305
LNE: FZC33_07195
MET: M446_1327
MNO: Mnod_2371
MEE: DA075_16970
MTEA: DK419_08715
MIND: mvi_57260(benD)
RHZ: RHPLAN_59320
RUT: FIU92_22560(novJ)
CMAR: IMCC12053_2583
CEH: CEW89_02920(benD)
CON: TQ29_16490(benD)
SULD: B5M07_19090(benD)
RMM: ROSMUCSMR3_03736(lvr)
ROK: RAK1035_2575
ROT: FIV09_19530(ycdF3)
PDE: Pden_1180
PCON: B0A89_14340(benD)
PZH: CX676_12390(benD)
PPAN: ESD82_01805
PSAN: HGN31_00295
TEC: AKL02_003795
NAR: Saro_0540 Saro_3837
NPP: PP1Y_AT15839 PP1Y_AT31260
NPN: JI59_24685
NRE: BES08_19580(benD)
NOG: GKE62_05255
NDR: HT578_08795
SWI: Swit_2636 Swit_5024
SPHD: HY78_12335(benD)
SPHM: G432_15085(benD)
SECH: B18_24650
SPHR: BSY17_105
SPHT: K426_21224(benD)
SYA: A6768_16780(benD)
SBAR: H5V43_22415
SPHY: CHN51_07050
BLAS: BSY18_3981
BFW: B5J99_00990(benD)
ALB: AEB_P2434
CNA: AB433_18075
ERY: CP97_14260
RGI: RGI145_20865(benD)
RMUC: FOB66_02980
AZL: AZL_a07370(benD)
AZM: DM194_25860
SMUC: JL100_027665
SROE: JL101_026020
PARH: I5S86_15030
MMAT: MMAGJ_52720(benD)
CGL: Cgl2407(Cgl2407)
CGB: cg2640(benD)
CGU: WA5_2323(BenD)
CGT: cgR_2288
CGS: C624_11685(benD)
CGG: C629_11695(benD)
CGM: cgp_2640(benD)
CGJ: AR0_11525(benD)
CGQ: CGLAR1_11375(benD)
CGX: SB89_11180(benD)
CEF: CE2308
CHN: A605_11140(benD)
CCN: H924_10135(benD)
CMD: B841_10265(benD)
CII: CIMIT_11045(benD)
CMQ: B840_09755(xylL)
CDX: CDES_10945(benD)
CSTA: CSTAT_12750(benD)
CCJZ: ccrud_10715(benD)
CAMG: CAMM_12485(benD)
CSUR: N24_2477(benD)
CCYS: SAMEA4530656_0415(benD)
CYZ: C3B44_09185
CCOE: CETAM_10400(lvr)
COK: COCCU_10780(lvr2)
CCYC: SCMU_25440(benD)
CPOY: GP475_09410
BFV: C628_11665(benD)
RHA: RHA1_ro02387(benD)
RQI: C1M55_27410(benD)
ROP: ROP_21010(benD)
ROA: Pd630_LPD06583
RPY: Y013_13600(benD)
RBY: CEJ39_00980(benD)
RAV: AAT18_24450(benD)
RRZ: CS378_14030(benD)
RHQ: IM25_04945(benD)
RHOD: AOT96_07380(benD)
RRT: 4535765_04644(benD)
RCR: NCTC10994_02858(benD)
RKO: JWS14_12420
ROZ: CBI38_27130(benD)
RPSK: JWS13_33420
RGOR: NMQ04_19740(benD)
DTM: BJL86_1202
DPC: A6048_05505(benD)
DLU: A6035_05570(benD)
DKN: NHB83_05170
SQZ: FQU76_02750
STSU: B7R87_02845(benD)
ARU: ASPU41_14625(benD)
ARN: CGK93_10510(benD)
ACRY: AC20117_04985(benD)
ARTP: E5206_02265
APN: Asphe3_35130
PSUL: AU252_22710(benD)
PSNI: NIBR502771_06640
PSEY: GU243_07215
GLU: F0M17_16120
KPL: KPaMU14_10935(benD)
KFV: AS188_00025(benD)
KRS: EQG70_04345
SATK: SA2016_0099
CIG: E7744_08330
PAEY: KUF55_15625
SVI: Svir_19240
SHT: KO02_15975(benD)
FSE: DI487_06970
CSAL: NBC122_01822(ycdF)
 » show all
Reference
PMID:1740120
  Authors
Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S
  Title
cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.
  Journal
Eur J Biochem 204:113-20 (1992)
DOI:10.1111/j.1432-1033.1992.tb16612.x
  Sequence
[aci:ACIAD1439]

  All links  
Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (12)   
   KEGG ENZYME (1)   
   KEGG REACTION (8)   
   KEGG RCLASS (3)   
Gene (1137)   
   KEGG GENES (586)   
   KEGG MGENES (423)   
   RefGene (127)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (1168)   

Download RDF
KEGG   ENZYME: 1.3.1.25
Entry
EC 1.3.1.25                 Enzyme                                 
Name
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase;
dihydrodihydroxybenzoate dehydrogenase;
DHBDH;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase;
2-hydro-1,2-dihydroxybenzoate dehydrogenase;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase;
dihydrodihydroxybenzoate dehydrogenase;
(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
Reaction(IUBMB)
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+ [RN:R00813]
Reaction(KEGG)
R00813;
(other) R08111 R08112 R08113
Substrate
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate [CPD:C06321];
NAD+ [CPD:C00003]
Product
catechol [CPD:C00090];
CO2 [CPD:C00011];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.3.1.25 created 1976, modified 2004 (EC 1.3.1.55 created 1999, incorporated 2004)
Pathway
ec00362  Benzoate degradation
ec00364  Fluorobenzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05783  dihydroxycyclohexadiene carboxylate dehydrogenase
Genes
EFE: EFER_1485(benD)
KPN: KPN_01869
KPU: KP1_2934
KPM: KPHS_28390
KPP: A79E_2376
KPH: KPNIH24_14210(benD)
KPZ: KPNIH27_13570(benD)
KPV: KPNIH29_14240(benD)
KPW: KPNIH30_14505(benD)
KPY: KPNIH31_13520(benD)
KPG: KPNIH32_14400(benD)
KPC: KPNIH10_14040(benD)
KPQ: KPR0928_14020(benD)
KPT: VK055_0615
KPO: KPN2242_12265(benD)
KPR: KPR_2933(benD)
KPJ: N559_2421
KPI: D364_09585(benD)
KPA: KPNJ1_02608
KPS: KPNJ2_02563
KPX: PMK1_04210(lvr)
KPB: FH42_05420(benD)
KPNE: KU54_012115(benD)
KPNU: LI86_12050(benD)
KPNK: BN49_2969(benD)
KVA: Kvar_2435
KPE: KPK_2488(cbeD)
KPK: A593_24210(benD)
KVD: KR75_22145(benD)
KVQ: SP68_02890(benD)
KOC: AB185_22235(benD)
KQU: AVR78_18380(benD)
EAE: EAE_19880(benD)
EAR: CCG29904
KQV: B8P98_13160(benD)
KAR: LGL98_11655
KGR: JJJ10_14635
ROR: RORB6_06755(benD)
RON: TE10_13830(benD)
RPLN: B1209_13860(benD)
RAO: DSD31_13375
RTG: NCTC13098_03815(lvr_2)
CSED: JY391_11115
CAF: AL524_15085
CFAR: CI104_13175(benD)
CIR: C2U53_22220(benD)
CTEL: GBC03_17315
EBT: EBL_c18160
PGE: LG71_16210(benD)
BUF: D8682_03275
IZH: FEM41_18110
PSGC: G163CM_11650(lvr)
EBF: D782_2133
EBU: CUC76_01775(benD)
SMW: SMWW4_v1c30600
SMAF: D781_2850
SRZ: AXX16_2219
SERM: CLM71_14595(benD)
SFJ: SAMEA4384070_3090(xecD)
SSUR: ATE40_011850(benD)
SRHZ: FO014_19065
SENP: KHA73_15020
SNEM: NLX84_15360(benD)
RBAD: H2866_19745
XSA: SB85_10140(benD)
PSD: DSC_14910(benD)
VNA: PN96_18365(benD)
VEJ: VEJY3_17926(benD)
VJP: NP165_16980(benD)
PAE: PA2515(xylL)
PAEV: N297_2586
PAEI: N296_2586
PAU: PA14_32130(xylL)
PAP: PSPA7_2722(xylL)
PAG: PLES_27801(xylL)
PAF: PAM18_2524(benD)
PNC: NCGM2_3520(benD)
PAEB: NCGM1900_4012(benD)
PDK: PADK2_12670(benD)
PSG: G655_12450(benD)
PRP: M062_13075(benD)
PAEP: PA1S_13070(benD)
PAER: PA1R_gp0309
PAEM: U769_12650(benD)
PAEL: T223_14270(benD)
PAES: SCV20265_2794
PAEU: BN889_02739(benD)
PAEG: AI22_20850(benD)
PAEC: M802_2583
PAEO: M801_2451
PMK: MDS_4167
PRE: PCA10_30910(benD)
PPSE: BN5_3608(benD)
PFUW: KF707C_15520(bzaB) KF707C_28440
PCQ: PcP3B5_23360(lvr)
PPAA: B7D75_12600
PPU: PP_3164(benD)
PPF: Pput_2551
PPG: PputGB1_2685
PPW: PputW619_2707
PPT: PPS_2762
PPB: PPUBIRD1_2569(benD)
PPI: YSA_10652
PPX: T1E_1059(benD)
PPUH: B479_13460(benD)
PPUT: L483_17645(benD)
PPUN: PP4_25400(benD) PP4_48180(benD)
PPUD: DW66_3021
PFV: Psefu_2026
PMON: X969_13160(benD)
PMOT: X970_12805(benD)
PPJ: RK21_01914
PFL: PFL_3855(xylL)
PPRC: PFLCHA0_c39130(xylL)
PPRO: PPC_3951(benD)
PFE: PSF113_2894(benD)
PFN: HZ99_02920(benD)
PFO: Pfl01_2324 Pfl01_2965(benD)
PMAN: OU5_6167(xylL)
PAZO: AYR47_21845(benD)
PFX: A7318_13915(benD)
PEN: PSEEN3140(benD)
PLUL: FOB45_00445
PBA: PSEBR_a2882
PPUU: PputUW4_03254(xylL)
PDR: H681_11365(benD)
PSV: PVLB_12230(benD)
PKC: PKB_2103(xylL)
PCH: EY04_20395(benD)
PCZ: PCL1606_21670
PCP: JM49_10825(benD)
PFZ: AV641_09800(benD)
PLQ: AA042_19050(benD)
PALK: PSAKL28_52390
PSES: PSCI_4806(benD)
PSEM: TO66_21090(benD)
PPSY: AOC04_06645(benD)
PSOS: POS17_3976(benD)
PFK: PFAS1_22860(benD)
PPSL: BJP27_02335(benD)
PSET: THL1_2895
PSIL: PMA3_10990(benD)
PYM: AK972_2990
PALL: UYA_06695(benD) UYA_20405(benD)
PUM: HGP31_18590
PPSH: G5J76_17155
PGY: AWU82_15480(benD)
PLAL: FXN65_12620
PEZ: HWQ56_13965
PDW: BV82_2263
PZE: HU754_016970
PSEP: C4K39_5809
PTZ: HU718_017520
PSHH: HU773_013520
PANH: HU763_012295
PAZE: KSS91_10650
PORY: EJA05_13820
PWZ: J7655_17885
PTK: EXN22_01370
PTW: TUM18999_29750(xylL)
PTAE: NCTC10697_02700(benD)
PGF: J0G10_14060
PCAV: D3880_08570
PJU: L1P09_13265
PPHN: HU825_11445
PIZ: LAB08_R37340
PSIH: LOY51_13760
PFIT: KJY40_13375
PSA: PST_1670(benD)
PSR: PSTAA_1698(benD)
PSC: A458_09170(benD)
PSJ: PSJM300_08880(benD)
PSH: Psest_2696
PSTU: UIB01_13630(benD)
PSED: DM292_11225
PCHL: LLJ08_12930
PBM: CL52_07430(benD)
PKG: LW136_09530
SDEG: GOM96_16690
AVN: Avin_08620(benD)
AVL: AvCA_08620(benD)
AVD: AvCA6_08620(benD)
ACX: Achr_32810(benD)
HPEG: EAO82_00580
PBAU: OS670_01855
MHC: MARHY0281(benD)
MAD: HP15_1108
MPQ: ABA45_01255(benD)
MARI: ACP86_12000(benD)
PCR: Pcryo_1264
PSO: PSYCG_06665(benD)
PALI: A3K91_1588
PSPG: AK823_04985
PSYG: AK825_05000
PSYP: E5677_05445
ACB: A1S_1212
ABY: ABAYE2558(benD)
ABC: ACICU_01189
ABN: AB57_1347
ABB: ABBFA_02336(lvr)
ABX: ABK1_1644
ABZ: ABZJ_01348
ABR: ABTJ_02517
ABD: ABTW07_1376
ABH: M3Q_1568
ABAD: ABD1_12210(benD)
ABJ: BJAB07104_01359
ABAB: BJAB0715_01371
ABAJ: BJAB0868_01307
ABAZ: P795_11430
ABK: LX00_05835
ABAU: IX87_04590
ABAA: IX88_08130
ABW: BL01_13775
ABAL: ABLAC_20300
ACC: BDGL_000463(benD)
ANO: RR32_12270
ALC: OTEC02_13000
ACAL: BUM88_05780
ASEI: I8T81_13015
ACD: AOLE_13350(benD)
ACI: ACIAD1439(benD)
ATT: AMQ28_00600
AEI: AOY20_11285
AJO: RZ95_08915
ACW: A0J50_11650
ACV: AMD27_07845
AJN: BVL33_09975
ASOL: BEN76_06765
ASJ: AsACE_CH01477(benD)
AID: CTZ23_07100
ADV: DJ533_10820
ARJ: DOM24_07535
AWU: BEN71_06045
ACUM: C9E88_012210
AGU: AS4_23700(benD)
ALW: FOB21_01940
ADS: FPL17_10305
ABER: BSR55_11570
ATN: FM020_08965
ALJ: G8D99_08475
ATG: J4G44_08925
AVB: RYU24_15340(benD)
ABOU: ACBO_16050(benD)
AGYL: FPL18_02705
AVZ: HWI77_08295
MOI: MOVS_09455
AMG: AMEC673_15500(benD)
ALR: DS731_05535
CYQ: Q91_2245
CZA: CYCME_2563(benD)
CYY: CPC19_01575
HAK: KO116_00235
HHU: AR456_17680(benD)
HSI: BOX17_05810(benD)
HHH: CLM76_07040(benD)
HBE: BEI_1519
HCAM: I4484_18800
HPIZ: GYM47_16275
HPRO: LMS44_22930
HQD: K1Y77_14475
APAC: S7S_13320
MME: Marme_1558
MARS: A8C75_10510(benD)
MGEO: CFI10_04840(benD)
MSEC: LN244_11355
MRZ: KDW95_03785
ASIM: FE240_08800
OCE: GU3_01775
ZDF: AN401_00165(benD)
GBI: PG2T_09665
VMS: LVJ82_06055
USU: LVJ78_07365
UTE: LVJ83_07960
PSE: NH8B_1753(benD)
RSC: RCFBP_11859(benD)
RSL: RPSI07_1884(benD)
RSN: RSPO_c01859
RSY: RSUY_19290
RPI: Rpic_1367
RPF: Rpic12D_1431
RPJ: N234_27840 N234_37270(benD)
RMN: TK49_11665(benD)
RIN: ACS15_1754
RSG: JK151_11745
RWE: KOL96_15110
REH: H16_A1960(benD)
CNC: CNE_1c19300(benD)
CUH: BJN34_08575(benD)
REU: Reut_B4406
RME: Rmet_4885(benD)
CBW: RR42_s0554
CCUP: BKK81_23220(benD)
CUP: BKK80_33070(benD)
CUU: BKK79_23955(benD)
CPAU: EHF44_23095
COX: E0W60_20505 E0W60_32235
BMA: BMAA0184
BMV: BMASAVP1_1357(benD)
BML: BMA10229_1552(benD)
BMN: BMA10247_A0212(benD)
BMAL: DM55_3534
BMAE: DM78_4623
BMAQ: DM76_4231
BMAI: DM57_14455(benD)
BMAF: DM51_3935
BMAZ: BM44_3496
BMAB: BM45_4332
BPS: BPSS1906(benD)
BPM: BURPS1710b_A1002(benD)
BPL: BURPS1106A_A2584(benD)
BPD: BURPS668_A2728(benD)
BPSE: BDL_5312
BPSM: BBQ_4224
BPSU: BBN_5371
BPSD: BBX_4477
BPZ: BP1026B_II2045(benD)
BPQ: BPC006_II2547
BPK: BBK_4645
BPSH: DR55_5828
BPSA: BBU_4103
BPSO: X996_5626
BUT: X994_5189
BTE: BTH_II0470
BTQ: BTQ_3763
BTJ: BTJ_4794
BTZ: BTL_5580
BTD: BTI_5084
BTV: BTHA_4621
BTHE: BTN_5251
BTHM: BTRA_5521
BTHA: DR62_5380(benD)
BTHL: BG87_5596
BOK: DM82_6196
BOC: BG90_4468
BUU: WS70_27015(benD)
BSAV: WS86_28725(benD)
BHG: I6G56_27550
BVI: Bcep1808_5828
BVE: AK36_5311
BUR: Bcep18194_C7049
BCM: Bcenmc03_6134
BCH: Bcen2424_6527
BCEN: DM39_5094
BCEW: DM40_5132
BCEO: I35_7537
BAM: Bamb_6581
BAC: BamMC406_6296
BMU: Bmul_3241
BMK: DM80_4620
BMUL: NP80_3313
BCED: DM42_7057
BCEP: APZ15_36345(benD)
BDL: AK34_5715
BPYR: ABD05_32070(benD)
BCON: NL30_37450(benD)
BUB: BW23_4425
BDF: WI26_27680(benD)
BLAT: WK25_16340(benD)
BTEI: WS51_27265(benD)
BSEM: WJ12_16745(benD)
BPSL: WS57_00510(benD)
BMEC: WJ16_18210(benD)
BSTG: WT74_22610(benD)
BSTL: BBJ41_36465(benD)
BARI: NLX30_38100(benD)
BUG: BC1001_1344
BGO: BM43_5498
BYI: BYI23_D002180
BUK: MYA_5341
BUE: BRPE67_DCDS03930
BUL: BW21_4619
BUQ: AC233_11160
BUD: AQ610_29995(benD)
BUM: AXG89_16415(benD)
BUI: AX768_26125(benD)
BURK: DM992_37910
BXE: Bxe_B0912(benD)
BXB: DR64_6233
BPH: Bphy_5349
BGE: BC1002_6177
BPX: BUPH_01851
BPY: Bphyt_1594
BUZ: AYM40_26005(benD)
BCAI: K788_0005752
PSPW: BJG93_32100
PARB: CJU94_35245(benD) CJU94_37920(benD)
PHS: C2L64_29825(benD) C2L64_48515(benD)
PTER: C2L65_18575(benD)
PCJ: CUJ87_08370(benD)
PTS: CUJ90_10080(benD)
PCAF: DSC91_002403
PTRO: G5S35_36180
PGIS: I6I06_20450 I6I06_20465
PACP: FAZ97_31360
PACS: FAZ98_17695
PDIO: PDMSB3_2246.1(benD)
CABA: SBC2_79750
BUO: BRPE64_DCDS08510
BPT: Bpet1396(benD)
BHO: D560_1121
BHM: D558_1108
BTRM: SAMEA390648701944(benD)
AXY: AXYL_01800
AIS: BUW96_17365
ACHR: C2U31_10450(benD)
ACHB: DVB37_15210
ACHO: H4P35_21825
AFA: UZ73_17880(benD)
AFQ: AFA_08575(benD)
AAQU: D3M96_09795
AAMM: FE795_07790
OUR: CEQ07_11095
OUE: I6G29_07010
PNA: Pnap_2109
ACRA: BSY15_1216
CSER: CCO03_07070(benD)
CODO: LAD35_11955
ADN: Alide_2649
HPSE: HPF_01835(lvr)
DIH: G7047_12820
SIMP: C6571_19145
JAJ: EKL02_16455
JAS: FJQ89_23180
HSE: Hsero_1311(cbeD)
HSZ: ACP92_06560(benD)
HRB: Hrubri_1137(cbeD)
HHF: E2K99_06475
HFR: G5S34_06740
MASW: AM586_16570(benD)
MALI: EYF70_17200
MUM: FCL38_01220
GLC: JQN73_16180
AON: DEH84_15075
RBU: PG1C_04535
DAR: Daro_2781
DDEN: KI615_11390
TMZ: Tmz1t_3099
THK: CCZ27_03210(benD) CCZ27_16240(benD)
AMIH: CO731_00666(ydaD)
PHT: BLM14_21520(benD)
SFH: SFHH103_03581
SFD: USDA257_c54420(benD)
SINO: SS05631_c27060
EAD: OV14_a1474(fabG2)
EAH: FA04_27030(benD)
ESJ: SJ05684_b58660
EAK: EKH55_4347
ARA: Arad_12206
RHK: Kim5_CH01085(benD)
RSUL: N2599_31260(benD)
BBET: F8237_17750
BOS: BSY19_2041
XAU: Xaut_4355
XDI: EZH22_09305
LNE: FZC33_07195
MET: M446_1327
MNO: Mnod_2371
MEE: DA075_16970
MTEA: DK419_08715
MIND: mvi_57260(benD)
RHZ: RHPLAN_59320
RUT: FIU92_22560(novJ)
CMAR: IMCC12053_2583
CEH: CEW89_02920(benD)
CON: TQ29_16490(benD)
SULD: B5M07_19090(benD)
RMM: ROSMUCSMR3_03736(lvr)
ROK: RAK1035_2575
ROT: FIV09_19530(ycdF3)
PDE: Pden_1180
PCON: B0A89_14340(benD)
PZH: CX676_12390(benD)
PPAN: ESD82_01805
PSAN: HGN31_00295
TEC: AKL02_003795
NAR: Saro_0540 Saro_3837
NPP: PP1Y_AT15839 PP1Y_AT31260
NPN: JI59_24685
NRE: BES08_19580(benD)
NOG: GKE62_05255
NDR: HT578_08795
SWI: Swit_2636 Swit_5024
SPHD: HY78_12335(benD)
SPHM: G432_15085(benD)
SECH: B18_24650
SPHR: BSY17_105
SPHT: K426_21224(benD)
SYA: A6768_16780(benD)
SBAR: H5V43_22415
SPHY: CHN51_07050
BLAS: BSY18_3981
BFW: B5J99_00990(benD)
ALB: AEB_P2434
CNA: AB433_18075
ERY: CP97_14260
RGI: RGI145_20865(benD)
RMUC: FOB66_02980
AZL: AZL_a07370(benD)
AZM: DM194_25860
SMUC: JL100_027665
SROE: JL101_026020
PARH: I5S86_15030
MMAT: MMAGJ_52720(benD)
CGL: Cgl2407(Cgl2407)
CGB: cg2640(benD)
CGU: WA5_2323(BenD)
CGT: cgR_2288
CGS: C624_11685(benD)
CGG: C629_11695(benD)
CGM: cgp_2640(benD)
CGJ: AR0_11525(benD)
CGQ: CGLAR1_11375(benD)
CGX: SB89_11180(benD)
CEF: CE2308
CHN: A605_11140(benD)
CCN: H924_10135(benD)
CMD: B841_10265(benD)
CII: CIMIT_11045(benD)
CMQ: B840_09755(xylL)
CDX: CDES_10945(benD)
CSTA: CSTAT_12750(benD)
CCJZ: ccrud_10715(benD)
CAMG: CAMM_12485(benD)
CSUR: N24_2477(benD)
CCYS: SAMEA4530656_0415(benD)
CYZ: C3B44_09185
CCOE: CETAM_10400(lvr)
COK: COCCU_10780(lvr2)
CCYC: SCMU_25440(benD)
CPOY: GP475_09410
BFV: C628_11665(benD)
RHA: RHA1_ro02387(benD)
RQI: C1M55_27410(benD)
ROP: ROP_21010(benD)
ROA: Pd630_LPD06583
RPY: Y013_13600(benD)
RBY: CEJ39_00980(benD)
RAV: AAT18_24450(benD)
RRZ: CS378_14030(benD)
RHQ: IM25_04945(benD)
RHOD: AOT96_07380(benD)
RRT: 4535765_04644(benD)
RCR: NCTC10994_02858(benD)
RKO: JWS14_12420
ROZ: CBI38_27130(benD)
RPSK: JWS13_33420
RGOR: NMQ04_19740(benD)
DTM: BJL86_1202
DPC: A6048_05505(benD)
DLU: A6035_05570(benD)
DKN: NHB83_05170
SQZ: FQU76_02750
STSU: B7R87_02845(benD)
ARU: ASPU41_14625(benD)
ARN: CGK93_10510(benD)
ACRY: AC20117_04985(benD)
ARTP: E5206_02265
APN: Asphe3_35130
PSUL: AU252_22710(benD)
PSNI: NIBR502771_06640
PSEY: GU243_07215
GLU: F0M17_16120
KPL: KPaMU14_10935(benD)
KFV: AS188_00025(benD)
KRS: EQG70_04345
SATK: SA2016_0099
CIG: E7744_08330
PAEY: KUF55_15625
SVI: Svir_19240
SHT: KO02_15975(benD)
FSE: DI487_06970
CSAL: NBC122_01822(ycdF)
 » show all
Reference
1  [PMID:4341530]
  Authors
Reiner AM.
  Title
Metabolism of aromatic compounds in bacteria. Purification and properties of the catechol-forming enzyme, 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid (NAD + ) oxidoreductase (decarboxylating).
  Journal
J Biol Chem 247:4960-5 (1972)
Reference
2  [PMID:1740120]
  Authors
Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S
  Title
cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.
  Journal
Eur J Biochem 204:113-20 (1992)
DOI:10.1111/j.1432-1033.1992.tb16612.x
  Sequence
[aci:ACIAD1439]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.25
IUBMB Enzyme Nomenclature: 1.3.1.25
ExPASy - ENZYME nomenclature database: 1.3.1.25
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.25
BRENDA, the Enzyme Database: 1.3.1.25
CAS: 60496-16-4

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Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (1137)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (586)   
   KEGG MGENES (423)   
   RefGene (127)   
Protein sequence (4731)   
   UniProt (1430)   
   SWISS-PROT (2)   
   RefSeq(pep) (3299)   
DNA sequence (33836)   
   RefSeq(nuc) (27212)   
   GenBank (3805)   
   EMBL (2819)   
Protein domain (3)   
   InterPro (3)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (39735)   

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KEGG   REACTION: R08112
Entry
R08112                      Reaction                               
Name
5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating)
Definition
5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
Equation
C16479 + C00003 <=> C16473 + C00004 + C00011 + C00080
Reaction class
RC00001  C00003_C00004
RC00271  C16473_C16479
Enzyme
1.3.1.25
Pathway
rn00364  Fluorobenzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Orthology
K05783  dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   UMBBD-RN (1)   
Gene (587)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (586)   
All databases (606)   

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