KEGG   ORTHOLOGY: K05898
Entry
K05898                      KO                                     
Symbol
kstD
Name
3-oxosteroid 1-dehydrogenase [EC:1.3.99.4]
Pathway
map00984  Steroid degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K05898  kstD; 3-oxosteroid 1-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.99  With unknown physiological acceptors
    1.3.99.4  3-oxosteroid 1-dehydrogenase
     K05898  kstD; 3-oxosteroid 1-dehydrogenase
Other DBs
RN: R09884
COG: COG1053
GO: 0047571
Genes
RBAD: H2866_16870
SOD: Sant_0955
EBI: EbC_17210
PAO: Pat9b_1567
VAF: D1115_23240
PRE: PCA10_12340(kstD)
PFUW: KF707C_11690
PPUT: L483_14095
PPUN: PP4_27200(kstD3)
PVR: PverR02_11670
PKC: PKB_4330
PSET: THL1_1313
PSIL: PMA3_11570
PTAE: NCTC10697_02063(kstD_3)
SPL: Spea_2125
SHL: Shal_2097
PHA: PSHAa2133(tesH)
PTN: PTRA_a2586(kstD)
PNG: PNIG_a2780(kstD)
REH: H16_B0639(h16_B0639)
CNC: CNE_2c05840(kstD) CNE_BB1p03860(ksdD1) CNE_BB1p04140(kstD)
BCJ: BCAM1646
BCEO: I35_5506
BMUL: NP80_3988
BCED: DM42_6312(kstD)
BCON: NL30_03955
BTEI: WS51_05855
BMEC: WJ16_26970
BXB: DR64_7938
BPH: Bphy_7441
BFN: OI25_4615
CABA: SBC2_48750(kstD)
BPE: BP3500
BPC: BPTD_3450
BPA: BPP0873
BBR: BB0967
CTES: O987_07760
EBA: p2A2 p2A323
APET: ToN1_32220
GME: Gmet_2225
PLA: Plav_1792
NEN: NCHU2750_12250(kstD) NCHU2750_48230(kstD)
RHT: NT26_3059
BARH: WN72_09200
KVL: KVU_PA0184(kstD3)
KVU: EIO_3010
SGI: SGRAN_3515(kstD)
SSAN: NX02_07685
SPHB: EP837_02950(urdA) EP837_03338(kstD)
ERF: FIU90_01650(kstD)
LSP: Bsph_0520
KZO: NCTC404_01577(ksdD) NCTC404_01892(kstD)
MTU: Rv3537(kstD)
MTV: RVBD_3537
MTC: MT3641
MRA: MRA_3576
MTUR: CFBS_3753
MTD: UDA_3537
MTUB: MT7199_3599(kstD)
MTUC: J113_24750
MTUE: J114_18915
MTUH: I917_24820
MTUL: TBHG_03477
MTUT: HKBT1_3738
MTUU: HKBT2_3747
MBO: BQ2027_MB3567(kstd)
MBB: BCG_3601
MBT: JTY_3602
MBX: BCGT_3403
MAF: MAF_35490
MMIC: RN08_3913
MCQ: BN44_110029(kstD)
MCV: BN43_90035(kstD)
MCX: BN42_90032(kstD)
MCZ: BN45_100032(kstD)
MLP: MLM_0768
MPSE: MPSD_49570 MPSD_52230(kstD)
MHAD: B586_04625
MBAI: MB901379_04185(kstD_1) MB901379_04190(kstD_2) MB901379_04416(kstD_3)
MSHJ: MSHI_39040
MPHL: MPHLCCUG_00564(ksdD_1) MPHLCCUG_02603(kstD_1) MPHLCCUG_02624(kstD_2) MPHLCCUG_03809(kstD_3) MPHLCCUG_05061(ksdD_2)
MTHN: 4412656_00940(kstD_1) 4412656_00942(kstD_2) 4412656_02901(kstD_3) 4412656_03103(kstD_4) 4412656_04053(ksdD)
MHAS: MHAS_00710(kstD_1) MHAS_02480(kstD_2) MHAS_02630(kstD_3) MHAS_03730(kstD_4)
MAUU: NCTC10437_02715(kstD_1) NCTC10437_02718(ksdD_1) NCTC10437_03987(kstD_2) NCTC10437_04972(ksdD_3) NCTC10437_05002(ksdD_4)
MANY: MANY_12790 MANY_32630(ksdD)
MFLV: NCTC10271_00507(ksdD_1) NCTC10271_01474(kstD_1) NCTC10271_02072(kstD_2) NCTC10271_02164(kstD_3)
MSTE: MSTE_00581
MSAL: DSM43276_00540(kstD_1) DSM43276_00767(kstD_2)
MTER: 4434518_03655(kstD)
ASD: AS9A_0160 AS9A_0923(kstD3)
CAMG: CAMM_03990
CCYS: SAMEA4530656_1797(kstD)
CCYC: SCMU_40160
NFR: ERS450000_01853(ksdD) ERS450000_03774(kstD_1) ERS450000_05822(kstD_2)
NAD: NCTC11293_01234(kstD_1) NCTC11293_04402(kstD_2) NCTC11293_04404(ksdD)
RER: RER_07370(kstD3) RER_12410(kstD2) RER_29470 RER_51050(kstD1)
RRT: 4535765_00579(kstD_1) 4535765_04009(kstD_2) 4535765_04044(kstD_3)
RCR: NCTC10994_02142(kstD_1) NCTC10994_03277(ksdD) NCTC10994_03321(kstD_2)
GBR: Gbro_0895
GPO: GPOL_c41290(kstD1) GPOL_c41370(kstD2)
GOR: KTR9_0802(kstD)
GRU: GCWB2_04100(kstD)
GOM: D7316_02535(ksdD) D7316_02574(kstD_1) D7316_02576(kstD_2) D7316_02586(kstD_3)
TPR: Tpau_3848
TPUL: TPB0596_41890(ksdD)
SDV: BN159_3882(kstD)
STRM: M444_05900
SALU: DC74_7450
SALL: SAZ_38455
SLX: SLAV_27450(kstD1) SLAV_33045(kstD2)
SGE: DWG14_03584(ksdD)
SNF: JYK04_01244(kstD)
IDO: I598_0510(ksdD)
ACIJ: JS278_02361(ksdD)
NCA: Noca_2780
NDK: I601_0580(kstD_1) I601_0607(kstD_2) I601_3473(ksdD)
NCX: Nocox_20135(ksdD1) Nocox_22200(ksdD2)
FAL: FRAAL4374
NML: Namu_2896
SACC: EYD13_11975(kstD)
AMYY: YIM_07935(ksdD) YIM_14440(kstD1) YIM_36690(kstD2)
PDX: Psed_2567
PAUT: Pdca_05130
KAL: KALB_5140
AFS: AFR_27765
CAI: Caci_5094
CWO: Cwoe_1511
AEQ: AEQU_0919
CBAC: JI75_04740
CAU: Caur_0376
TRO: trd_1806
HTU: Htur_3820
 » show all
Reference
  Authors
Knol J, Bodewits K, Hessels GI, Dijkhuizen L, van der Geize R
  Title
3-Keto-5alpha-steroid Delta(1)-dehydrogenase from Rhodococcus erythropolis SQ1 and its orthologue in Mycobacterium tuberculosis H37Rv are highly specific enzymes that function in cholesterol catabolism.
  Journal
Biochem J 410:339-46 (2008)
DOI:10.1042/BJ20071130
  Sequence
[rer:RER_07370]
Reference
  Authors
Ouellet H, Johnston JB, de Montellano PR
  Title
Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.
  Journal
Trends Microbiol 19:530-9 (2011)
DOI:10.1016/j.tim.2011.07.009
  Sequence
[mtu:Rv3537]

KEGG   ENZYME: 1.3.99.4
Entry
EC 1.3.99.4                 Enzyme                                 
Name
3-oxosteroid 1-dehydrogenase;
3-oxosteroid Delta1-dehydrogenase;
Delta1-dehydrogenase;
3-ketosteroid-1-en-dehydrogenase;
3-ketosteroid-Delta1-dehydrogenase;
1-ene-dehydrogenase;
3-oxosteroid:(2,6-dichlorphenolindophenol) Delta1-oxidoreductase;
4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase;
Delta1-steroid reductase;
3-oxosteroid:(acceptor) Delta1-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors
Sysname
3-oxosteroid:acceptor Delta1-oxidoreductase
Reaction(IUBMB)
a 3-oxosteroid + acceptor = a 3-oxo-Delta1-steroid + reduced acceptor [RN:R03748]
Reaction(KEGG)
R03748 > R09884
Substrate
3-oxosteroid [CPD:C01876];
acceptor [CPD:C00028]
Product
3-oxo-Delta1-steroid [CPD:C02941];
reduced acceptor [CPD:C00030]
History
EC 1.3.99.4 created 1965
Pathway
ec00984  Steroid degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05898  3-oxosteroid 1-dehydrogenase
Genes
RBADH2866_16870
SODSant_0955
EBIEbC_17210
PAOPat9b_1567
VAFD1115_23240
PREPCA10_12340(kstD)
PFUWKF707C_11690
PPUTL483_14095
PPUNPP4_27200(kstD3)
PVRPverR02_11670
PPUUPputUW4_01674
PKCPKB_4330
PFZAV641_10565
PLQAA042_20370
PPSYAOC04_07865
PSETTHL1_1313
PSILPMA3_11570
PKEDLD99_14695
PUMHGP31_15830 HGP31_20985
PPSHG5J76_13520
PLALFXN65_05785
PKHJLK41_05745
PAZEKSS91_19225
PPHABVH74_17930
PTAENCTC10697_02063(kstD_3)
PCAVD3880_17465
PPHNHU825_14720
PIZLAB08_R28000 LAB08_R40830
SDEGGOM96_01725
HARRHV822_17945
SPLSpea_2125
SHLShal_2097
COLWA3Q33_18535
CBERB5D82_11305
PHAPSHAa2133(tesH)
PTNPTRA_a2586(kstD)
PNGPNIG_a2780(kstD)
SNANI6N98_06520 I6N98_12630 I6N98_12735 I6N98_14795
ZALAZF00_05175
HJABST95_15060
HALCEY643_07420
AFUSEYZ66_12890
KAKKalk_07520
MSECLN244_04830
MRZKDW95_00825
ENWMJO57_10980
SDFACG33_00240 ACG33_03450
SOKD0B54_05120 D0B54_07290 D0B54_07645 D0B54_08710 D0B54_09355 D0B54_19275
SINIGT972_09335
FCEJN531_005735
GBIPG2T_07500 PG2T_14660
GPBHDN1F_02580
RINACS15_4393
REHH16_B0639(h16_B0639)
CNCCNE_2c05840(kstD) CNE_BB1p03860(ksdD1) CNE_BB1p04140(kstD)
CUHBJN34_30940
REUReut_A1543
CTIRALTA_B0488
CBWRR42_s2344
COXE0W60_08140
BURBcep18194_B1414
BCJBCAM1646
BCENDM39_6203 DM39_6493
BCEOI35_5506
BMULNP80_3988
BCTGEM_3819 GEM_4009
BCEDDM42_6312(kstD)
BCEPAPZ15_30825
BPYRABD05_27640
BCONNL30_03955
BDFWI26_21365
BTEIWS51_05855
BPSLWS57_05850 WS57_17450
BMECWJ16_26970
BSTLBBJ41_21525 BBJ41_35430
BANNJFN94_26170
BARINLX30_29990 NLX30_35350
BYIBYI23_C010760
BUEBRPE67_CCDS00170
BURKDM992_32455 DM992_41125
BXBDR64_7938
BPHBphy_7441
BFNOI25_4615
PSPWBJG93_29220
PVEUC34_06890
CABASBC2_48750(kstD)
BUOBRPE64_CCDS00170
BPEBP3500
BPCBPTD_3450
BPERBN118_0892 BN118_0895
BPETB1917_3279 B1917_3282
BPEUQ425_5990 Q425_6020
BPARBN117_3819 BN117_3822
BPABPP0873
BBHBN112_2476
BBRBB0967
BBMBN115_0926 BN115_0929
BBXBBS798_0941 BBS798_0944
CTTCtCNB1_1357
CTESO987_07760
ADKAlide2_4318
DIHG7047_09725
SWSI6J16_04070 I6J16_04345
BBAYA4V04_02290
DOEDENOEST_0776 DENOEST_1147 DENOEST_1377 DENOEST_3667 DENOEST_3674
EBAp2A2 p2A323
APETToN1_32220
FLEKI610_13350 KI610_13515
AZDCDA09_09370
THUAC731_008845
GMEGmet_2225
MSDMYSTI_04791 MYSTI_04825
SURSTAUR_1901
MRMA7982_08059
MESWA9K65_013385
PLAPlav_1792
SIXBSY16_5063
EAKEKH55_4631
RBQJ2J99_22330
NGLRG1141_PA07480
NENNCHU2750_12250(kstD) NCHU2750_48230(kstD)
RHTNT26_3059
SOJK6301_20385
OCHCES85_5632 CES85_5667(ksdD)
BOTCIT37_04025
BGQX265_40215
BGZXH91_34775
BARHWN72_09200
BDGLPJ38_36490
BBANJ4G43_044505
LNEFZC33_07685
APRAG3A50_13355
NTDEGO55_01175 EGO55_03150 EGO55_05950 EGO55_06800 EGO55_06870 EGO55_13510
CAENK5X80_05520 K5X80_08115 K5X80_13040 K5X80_14890
DEVOH4N61_04490
BRND1F64_03505
KVLKVU_PA0184(kstD3)
KVUEIO_3010
CONTQ29_17615
TPROGa0080559_TMP3710
PPANESD82_08150
NARSaro_3540 Saro_3626 Saro_3732
NPPPP1Y_AT32705 PP1Y_Mpl3421
NPNJI59_08515 JI59_08580
NREBES08_05000 BES08_05070
NOVTQ38_012610 TQ38_017115 TQ38_027060
NOTC7W88_10820 C7W88_19740 C7W88_20255
NGFFRF71_08520 FRF71_13305
NOGGKE62_06680 GKE62_06765
NDRHT578_14300
SGISGRAN_3515(kstD)
SPHOC3E99_12385
SWISwit_1830 Swit_1839 Swit_3358
SPHDHY78_08405 HY78_16385 HY78_16430 HY78_26490
RDICMV14_05590 CMV14_07380 CMV14_07470 CMV14_14470 CMV14_14575 CMV14_14605 CMV14_16805
SPHMG432_16115 G432_17580 G432_20560
SSANNX02_07685
SPKCKC8_00840 KC8_02850 KC8_05230
SPHAD3Y57_03675 D3Y57_15260
SLANGV829_01815
SBINSBA_ch2_4140
SJPSJA_C1-18540
SYBTZ53_05530
SBDATN00_11125 ATN00_16585
SPMIK663_17706 K663_22173
SPHBEP837_02950(urdA) EP837_03338(kstD)
SPHRBSY17_3477 BSY17_3832
SPHTK426_15965 K426_21984 K426_29275
SYAA6768_12370 A6768_22365 A6768_25440
SUFLFIL70_21945
SBARH5V43_19015
SPHGAZE99_00945 AZE99_04345 AZE99_15685
SFLASPHFLASMR4Y_02342(kstD) SPHFLASMR4Y_02381(kstD)
SPHYCHN51_05510
BLASBSY18_3610 BSY18_830
BFWB5J99_13335
SPHJBSL82_04290
SPZRG5C33_13760 G5C33_13970 G5C33_14155
PARJJ4G78_12930
PHAOHF685_05420
ALHG6N82_09410
ELQGa0102493_111097
ERFFIU90_01650(kstD)
PORLBG023_11288
PHZCHX26_01205 CHX26_05380
NAOY958_14880
NCBC0V82_14450
CSOALIS82_04945
LSPBsph_0520
LFUHR49_04970
LYSLBYS11_18460
LYZDCE79_01090 DCE79_12880
LYCFH508_0019420
LCAPICJ70_05590
PPSRI6J18_14680
PRDF7984_00995 F7984_05355 F7984_10365
BVJI5776_02510
BOUI5818_06765
KZONCTC404_01577(ksdD) NCTC404_01892(kstD)
DSYDSY0768 DSY1422
DHDDhaf_0777 Dhaf_0779 Dhaf_2538
DDHDesde_0650
DDLDesdi_0568 Desdi_1520 Desdi_1643
DEDDHBDCA_p2416
DECDCF50_p2428
MHAPJFY71_04880
MTURv3537(kstD)
MTVRVBD_3537
MTCMT3641
MRAMRA_3576
MTFTBFG_13570
MTBTBMG_03577
MTKTBSG_03603
MTZTBXG_003552
MTGMRGA327_21850
MTECCDC5079_3278
MTURCFBS_3753
MTLCCDC5180_3230
MTOMTCTRI2_3601
MTDUDA_3537
MTNERDMAN_3881
MTJJ112_19045
MTUBMT7199_3599(kstD)
MTUCJ113_24750
MTUEJ114_18915
MTXM943_18185
MTUHI917_24820
MTULTBHG_03477
MTUTHKBT1_3738
MTUUHKBT2_3747
MTQHKBS1_3750
MBOBQ2027_MB3567(kstd)
MBBBCG_3601
MBTJTY_3602
MBMBCGMEX_3599
MBKK60_036750
MBXBCGT_3403
MAFMAF_35490
MMICRN08_3913
MCEMCAN_35481
MCQBN44_110029(kstD)
MCVBN43_90035(kstD)
MCXBN42_90032(kstD)
MCZBN45_100032(kstD)
MPAMAP_0530c MAP_0696 MAP_1433c MAP_1483c
MAOMAP4_0384 MAP4_2359 MAP4_2412 MAP4_3168 MAP4_3173 MAP4_3337
MAVIRC58_01830 RC58_11725 RC58_11990 RC58_15700 RC58_15725 RC58_16550
MAVURE97_01840 RE97_11735 RE97_12000 RE97_15730 RE97_15755 RE97_16585
MAVMAV_0624 MAV_0880 MAV_2953 MAV_3039
MITOCO_05340 OCO_07360 OCO_27850 OCO_28770 OCO_41130
MIAOCU_05380 OCU_07370 OCU_27720 OCU_28630 OCU_41040
MIDMIP_00988 MIP_01273 MIP_03682 MIP_03826
MYOOEM_05410 OEM_07440 OEM_26320 OEM_27260 OEM_41390
MCHIAN480_02670 AN480_04835 AN480_14585 AN480_15055 AN480_21590
MIROCQ_05490 OCQ_07510 OCQ_26420 OCQ_27350 OCQ_42400
MMALCKJ54_02595 CKJ54_03685 CKJ54_12650 CKJ54_19625
MLPMLM_0768
MMANMMAN_10150 MMAN_11100 MMAN_22030 MMAN_22160 MMAN_29190 MMAN_48300(kstD) MMAN_50370
MSAMycsm_03156 Mycsm_04177 Mycsm_04180 Mycsm_04567 Mycsm_05774
MULMUL_0346 MUL_4098
MMIMMAR_4775 MMAR_5024
MMAEMMARE11_46040 MMARE11_46090 MMARE11_48340
MLIMULP_05004 MULP_05276
MPSEMPSD_49570 MPSD_52230(kstD)
MSHOMSHO_04970 MSHO_57920
MMCMmcs_0293 Mmcs_3784 Mmcs_4662
MKMMkms_0303 Mkms_3857 Mkms_4750
MJLMjls_0284 Mjls_3788 Mjls_5045
MMMW7S_02615 W7S_03600 W7S_13490 W7S_13950 W7S_20535
MKNMKAN_10210 MKAN_10235 MKAN_11850 MKAN_29060
MYVG155_04095 G155_04625 G155_09250 G155_20865
MYEAB431_15070 AB431_15085 AB431_21450 AB431_21475 AB431_26370
MGOAFA91_11065 AFA91_16195
MHADB586_04625
MDXBTO20_10365 BTO20_26120 BTO20_31205
MSHGMSG_01156 MSG_02465 MSG_02534 MSG_04313 MSG_04522(kstD)
MFJMFLOJ_07060 MFLOJ_08020 MFLOJ_22300 MFLOJ_41000 MFLOJ_42970 MFLOJ_43020
MSTOMSTO_08390 MSTO_09250 MSTO_26070 MSTO_44970(kstD) MSTO_47140
MSIMMSIM_13580 MSIM_29420 MSIM_31540 MSIM_52410
MSAKMSAS_05480 MSAS_06230 MSAS_17210 MSAS_17660 MSAS_26520 MSAS_28780
MKUI2456_13065 I2456_22795 I2456_25510
MGROFZ046_02645 FZ046_22890 FZ046_24685 FZ046_24710
MXEMYXE_06120(kstD) MYXE_10050 MYXE_17280
MNVMNVI_02640 MNVI_10130 MNVI_10180 MNVI_11600 MNVI_12190(kstD)
MPAGC0J29_07005 C0J29_15220 C0J29_19370 C0J29_26265 C0J29_26290 C0J29_27560
MNMMNVM_19110 MNVM_19140 MNVM_23930(ksdD) MNVM_26220
MGORH0P51_00565 H0P51_06215 H0P51_14395 H0P51_17945 H0P51_24505 H0P51_25615
MCOOMCOO_16140 MCOO_24650 MCOO_24700 MCOO_26250 MCOO_26880(kstD)
MBAIMB901379_04185(kstD_1) MB901379_04190(kstD_2) MB901379_04416(kstD_3)
MSEOMSEO_12560 MSEO_13510 MSEO_32180 MSEO_34160
MHEKJMUB5695_00511(kstD) JMUB5695_00572 JMUB5695_00958 JMUB5695_01797
MGAUMGALJ_02530 MGALJ_18150 MGALJ_23040 MGALJ_26320 MGALJ_38010(ksdD)
MLJMLAC_02380 MLAC_47770
MBRDMBRA_20360(kstD) MBRA_21000 MBRA_23080
MSHJMSHI_39040
MKRMKOR_35770(kstD) MKOR_36640 MKOR_36670
MDFK0O62_15945 K0O62_15955 K0O62_20760 K0O62_25485
MMAMK3U93_11770 K3U93_12050 K3U93_21205 K3U93_22485
MHOLK3U96_03300 K3U96_07985 K3U96_09520
MHERK3U94_19590 K3U94_20800
MSENK3U95_09050 K3U95_25175
MPAEK0O64_14475 K0O64_14535 K0O64_20985 K0O64_25865
MSPGF6B93_20300
MOTLTS72_01395 LTS72_11060 LTS72_28120
MVMMJO54_19495 MJO54_20715
MRFMJO55_19205 MJO55_23915
MPAAMKK62_02600 MKK62_02835 MKK62_03605 MKK62_07855
MCROMI149_15275 MI149_15390 MI149_21560 MI149_26175
MSMMSMEG_2869 MSMEG_4864 MSMEG_5941
MSGMSMEI_2793 MSMEI_2795 MSMEI_4739 MSMEI_5781
MSBLJ00_14260 LJ00_14270 LJ00_24055 LJ00_29375
MSNLI99_14265 LI99_14275 LI99_24060 LI99_29380
MSHLI98_14270 LI98_14280 LI98_24065 LI98_29385
MVAMvan_2865 Mvan_2868 Mvan_4243 Mvan_5237
MGIMflv_1519 Mflv_2403 Mflv_4567
MSPMspyr1_09030 Mspyr1_18350 Mspyr1_39670
MCBMycch_1568 Mycch_3687 Mycch_4569 Mycch_4602
MNED174_24280
MYNMyAD_23820
MFTXA26_07720 XA26_08840 XA26_18500 XA26_42560
MPHLMPHLCCUG_00564(ksdD_1) MPHLCCUG_02603(kstD_1) MPHLCCUG_02624(kstD_2) MPHLCCUG_03809(kstD_3) MPHLCCUG_05061(ksdD_2)
MVQMYVA_1642 MYVA_1644(kstD2) MYVA_4046 MYVA_5095 MYVA_5132
MLLB1R94_12240 B1R94_20215 B1R94_20230 B1R94_24995
MRHMycrhN_2293 MycrhN_3920 MycrhN_4239 MycrhN_4735 MycrhN_6267
MTHN4412656_00940(kstD_1) 4412656_00942(kstD_2) 4412656_02901(kstD_3) 4412656_03103(kstD_4) 4412656_04053(ksdD)
MHASMHAS_00710(kstD_1) MHAS_02480(kstD_2) MHAS_02630(kstD_3) MHAS_03730(kstD_4)
MDUMDUV_04270 MDUV_26880 MDUV_26900 MDUV_49630(ksdD) MDUV_49960
MCHTMCHIJ_12910 MCHIJ_12930 MCHIJ_19770(ksdD) MCHIJ_29350 MCHIJ_48880
MAUUNCTC10437_02715(kstD_1) NCTC10437_02718(ksdD_1) NCTC10437_03987(kstD_2) NCTC10437_04972(ksdD_3) NCTC10437_05002(ksdD_4)
MMAGMMAD_39640 MMAD_39690 MMAD_48010(ksdD)
MMORMMOR_12240(ksdD) MMOR_23060 MMOR_26630 MMOR_47180
MFXMFAL_01380 MFAL_01430 MFAL_33570(ksdD) MFAL_33830
MAICMAIC_05720(ksdD) MAIC_26450 MAIC_26590 MAIC_37900 MAIC_37950
MIJMINS_00210(ksdD) MINS_06050 MINS_35280 MINS_42990 MINS_43300
MALVMALV_19860 MALV_29540 MALV_42690(ksdD) MALV_51970
MTYMTOK_22730(ksdD) MTOK_23200
MPSCMPSYJ_16270(ksdD) MPSYJ_16570 MPSYJ_25770
MARZMARA_48380(ksdD) MARA_57590 MARA_57640 MARA_60850
MGADMGAD_00930 MGAD_06670 MGAD_21490 MGAD_37090(ksdD) MGAD_56270
MHEVMHEL_04970 MHEL_28200(ksdD) MHEL_49620 MHEL_49760
MSARMSAR_10570(ksdD) MSAR_31350 MSAR_41470 MSAR_41500
MANYMANY_12790 MANY_32630(ksdD)
MAUBMAUB_26370(ksdD) MAUB_35860 MAUB_54650
MPOFMPOR_43460 MPOR_53100 MPOR_53450(ksdD)
MPHUMPHO_14520 MPHO_34410 MPHO_43990(ksdD)
MMUCC1S78_000950 C1S78_011030 C1S78_019365 C1S78_025295
MMATMMAGJ_01320 MMAGJ_34810(ksdD)
MBOKMBOE_04220(ksdD) MBOE_19660 MBOE_31250
MFGK6L26_05660 K6L26_10870 K6L26_27825
MSEIMSEDJ_02000(ksdD) MSEDJ_47750 MSEDJ_51160
MFLVNCTC10271_00507(ksdD_1) NCTC10271_01474(kstD_1) NCTC10271_02072(kstD_2) NCTC10271_02164(kstD_3)
MCEEMCEL_05820 MCEL_38250(ksdD) MCEL_47590
MMONEWR22_01570 EWR22_19460 EWR22_25205
MABMAB_0081 MAB_0622c
MMVMYCMA_0051 MYCMA_0322
MABBMASS_0083 MASS_0592
MABLMMASJCM_0084 MMASJCM_0611
MCHEBB28_00395 BB28_02980
MIZBAB75_00695 BAB75_03730
MSTEMSTE_00581
MSAOMYCSP_02680
MSALDSM43276_00540(kstD_1) DSM43276_00767(kstD_2)
MJDJDM601_3456 JDM601_3683 JDM601_4271 JDM601_4274
MTER4434518_03655(kstD)
MMINMMIN_06930 MMIN_06960 MMIN_12060(ksdD)
MHIBMHIB_24040 MHIB_24070 MHIB_28520 MHIB_28570 MHIB_30730(ksdD)
ASDAS9A_0160 AS9A_0923(kstD3)
MPAKMIU77_02175 MIU77_10760
CGTcgR_2519 cgR_2520
CGSC624_12845 C624_12850
CGGC629_12850 C629_12855
CGJAR0_12605 AR0_12610
CGQCGLAR1_12470 CGLAR1_12475
CGXSB89_12310 SB89_12315
CHNA605_01175
CMDB841_08615
CGYCGLY_11530
CCJZccrud_00210 ccrud_11775 ccrud_11780
CAMGCAMM_03990
CSURN24_0047(kstD) N24_2696 N24_2697
CCYSSAMEA4530656_1797(kstD)
CCYCSCMU_40160
BFVC628_12940 C628_12945
NFANFA_40910 NFA_4630
NFRERS450000_01853(ksdD) ERS450000_03774(kstD_1) ERS450000_05822(kstD_2)
NCYNOCYR_0490 NOCYR_2410 NOCYR_2412(ksdD)
NBRO3I_002610
NNONONO_c04910 NONO_c44710 NONO_c59000(kstD) NONO_c75370
NSLBOX37_02140 BOX37_11775 BOX37_11785
NSRNS506_00508(kstD) NS506_01255 NS506_04161 NS506_06834
NTPCRH09_03190 CRH09_08310
NOZDMB37_06020 DMB37_23555
NODFOH10_05055 FOH10_22780 FOH10_28785
NAHF5544_02600 F5544_38210
NADNCTC11293_01234(kstD_1) NCTC11293_04402(kstD_2) NCTC11293_04404(ksdD)
NWLNWFMUON74_04860 NWFMUON74_27380 NWFMUON74_27420
NIEKV110_02990
NTCKHQ06_03710 KHQ06_28340 KHQ06_35340
NHUH0264_03790 H0264_31285 H0264_34515
NYALTV02_02905 LTV02_28925 LTV02_38485
NGPLTT66_15365 LTT66_28670 LTT66_34675
RHARHA1_ro02483 RHA1_ro04532(kstD) RHA1_ro05798 RHA1_ro09040(kstD)
RERRER_07370(kstD3) RER_12410(kstD2) RER_29470 RER_51050(kstD1)
REYO5Y_03580 O5Y_05765 O5Y_13455 O5Y_15475 O5Y_24190
REBXU06_03820 XU06_05985 XU06_13670 XU06_15710 XU06_24615
RQIC1M55_04065 C1M55_06235 C1M55_14680 C1M55_16725 C1M55_18985 C1M55_25780
ROPROP_22100 ROP_44470(kstD3) ROP_58590
ROAPd630_LPD00983 Pd630_LPD02417 Pd630_LPD02437 Pd630_LPD06709
RPYY013_10735 Y013_10770 Y013_14855 Y013_14890 Y013_19010
RBYCEJ39_05375 CEJ39_21530 CEJ39_21565
RAVAAT18_03885 AAT18_04135 AAT18_20780 AAT18_21795 AAT18_24755
RHWBFN03_15240
RRZCS378_10100 CS378_14320 CS378_19545 CS378_19770
RHQIM25_02475 IM25_02510 IM25_08860
RHODAOT96_05530 AOT96_14460 AOT96_16625 AOT96_24885 AOT96_26910 AOT96_29615
RRT4535765_00579(kstD_1) 4535765_04009(kstD_2) 4535765_04044(kstD_3)
RCRNCTC10994_02142(kstD_1) NCTC10994_03277(ksdD) NCTC10994_03321(kstD_2)
RTMG4H71_07435 G4H71_10725 G4H71_11670
RKOJWS14_13035 JWS14_14245 JWS14_24450 JWS14_31710 JWS14_40250 JWS14_41770
RGOKYT97_12825 KYT97_23100
ROZCBI38_00765 CBI38_01185 CBI38_01375 CBI38_30315
RPSKJWS13_12200 JWS13_20475 JWS13_32850
RGORNMQ04_02500
REQREQ_06770 REQ_10320 REQ_13080 REQ_15820 REQ_30200 REQ_43820
GBRGbro_0895
GPOGPOL_c41290(kstD1) GPOL_c41370(kstD2)
GORKTR9_0802(kstD)
GOQACH46_03080 ACH46_03085 ACH46_03205
GTABCM27_02525 BCM27_02565 BCM27_04395 BCM27_04795 BCM27_04905
GOCCXX93_06405
GITC6V83_04225
GRUGCWB2_04100(kstD)
GOMD7316_02535(ksdD) D7316_02574(kstD_1) D7316_02576(kstD_2) D7316_02586(kstD_3)
GAVC5O27_00940 C5O27_10765
GODGKZ92_03850 GKZ92_16365
GAMGII34_01425 GII34_18440 GII34_18510 GII34_19590 GII34_22970
GPDGII33_03265 GII33_04220 GII33_04290 GII33_16000 GII33_21730
GJIH1R19_03800 H1R19_03935
GOILK459_05195 LK459_05210
GHNMVF96_04170
GAMIIHQ52_06740
GMGNWF22_15340 NWF22_15625
SPINKV203_17400
TPRTpau_3848
TSMASU32_21920
TPULTPB0596_41890(ksdD)
DTMBJL86_0683
DITC3V38_09215 C3V38_11995
DIZCT688_03130
DPCA6048_03075 A6048_06195
DLUA6035_02460 A6035_03375 A6035_06275
DKNNHB83_02925
CBQAL705_04915
TOYFO059_01535 FO059_11435 FO059_14045
SMASAVERM_1595
SCBSCAB_63391 SCAB_77171
SDVBN159_3882(kstD)
SVTSVTN_35930
STRMM444_05900
STSIA4E84_23440
SLSSLINC_4924
SALUDC74_7450
SALLSAZ_38455
SLXSLAV_27450(kstD1) SLAV_33045(kstD2)
SGEDWG14_03584(ksdD)
SCYAEJ357_27015
SGZC0216_18530
SVNCP980_29965
SNKCP967_03180 CP967_03305
SHAWCEB94_23790
SGALCP966_21220
SAQUEJC51_28250
SPHVF9278_13155
SCHACP983_18170
SGXH4W23_38560
SCOECP976_25160
SNFJYK04_01244(kstD)
SFEUIM697_41345
SXNIAG42_03490
SLFJEQ17_45825
SDECL3078_14570
SYANNRK68_03380
SRUGF0345_00830
SAKBK1J60_30980
STAALDH80_36425
MAURBOH66_06275
MHOSCXR34_05695 CXR34_05735
MPRTET475_04315 ET475_04340
MSEDE3O41_04430
MSFIT882_05835
MTECOAU46_13995
AGFET445_03460
CRYB7495_17260
SUBTKPL76_01985
ARLAFL94_05105 AFL94_16925 AFL94_17005
ARYATC04_00425 ATC04_01165 ATC04_01250 ATC04_12780
ARQBWQ92_13440 BWQ92_20415
ARNCGK93_19195
ACRYAC20117_06590
ARTPE5206_02050 E5206_05325
AJGKKR91_14765
ASUNKG104_02805 KG104_15635
PSULAU252_17345
GLUF0M17_16240
GPRJQN66_17030
SATKSA2016_1183 SA2016_3921
IDOI598_0510(ksdD)
SANWG7063_10390
CWANKG103_18020
CFENKG102_05245
OEKFFI11_012845
PEIH9L10_15195
GEZFE251_00325 FE251_01985
PPCHMPREF9154_1971
PBOPACID_09620
AACIASQ49_16405
ACIJJS278_02361(ksdD)
MIKFOE78_09230
TFABW733_10375
TEJKDB89_05585
RAINRai3103_00195
PRVG7070_03450 G7070_05355
NCANoca_2780
NDKI601_0580(kstD_1) I601_0607(kstD_2) I601_3473(ksdD)
NDPE2C04_03060 E2C04_03095
NBEBack2_27140
NANOG5V58_01325 G5V58_09730
NAROCFH99_02530 CFH99_13585
NPIG7071_12475 G7071_15970
NPCKUV85_04260
PSIMKR76_01140 KR76_02655 KR76_14500 KR76_27115 KR76_27125
AEBC6I20_03230
MGGMPLG2_2464
MUZH4N58_14260
TCUTcur_0768 Tcur_3521
ACTWF7P10_03570 F7P10_28345 F7P10_28470
NOABKM31_03280
NOWGBF35_27970
NCXNocox_20135(ksdD1) Nocox_22200(ksdD2)
NGNLCN96_31195
FREFranean1_2897 Franean1_4718
FRIFraEuI1c_0561
FALFRAAL4374
NMLNamu_2896
SACGFDZ84_16245
SACCEYD13_11975(kstD)
AMDAMED_1344 AMED_2520
AMNRAM_06815 RAM_12810 RAM_36890
AMMAMES_1337 AMES_2492 AMES_7073
AMZB737_1338 B737_2493 B737_7073
AOIAORI_2482 AORI_3113
AJAAJAP_23800 AJAP_26415(ksdD)
AMQAMETH_4840
AMYCCU254_10450 CU254_23430 CU254_24040
AMYBBKN51_05010 BKN51_07725
AABA4R43_16055
AMYYYIM_07935(ksdD) YIM_14440(kstD1) YIM_36690(kstD2)
AORISD37_13475 SD37_15895
AACDLWP59_29210
APRTMUY14_23840 MUY14_29870
AROONQK81_07030 NQK81_09940
ATHML1857_26975
PDXPsed_2567
PHHAFB00_28935 AFB00_28945
PAUTPdca_05130
PBROHOP40_31105
SSYIEKG83_27235
KALKALB_5140
KPHYAOZ06_42840 AOZ06_47560
LEDBBK82_38755 BBK82_38950
ALOCRK57818 CRK59603
PMADBAY61_10945
SACEGIY23_13365
STPStrop_2629 Strop_2676
SAQSare_2826 Sare_2884
MICBMicB006_5170
MTUACSH63_14255
AMSAMIS_17420 AMIS_19000 AMIS_19140 AMIS_30780
AFSAFR_27765
AIHAiant_18290 Aiant_18980
PSUUPsuf_010640 Psuf_060860
CAICaci_5094
FLHEJ997_04545 EJ997_07985
BSOLFSW04_23915
CWOCwoe_1511
AYMYM304_04750
SHIShel_13870 Shel_26990
AEQAEQU_0919
CBACJI75_04740
RTSCE91St31_00710 CE91St31_06020 CE91St31_06250
ERZER308_09135
EUZDVS28_a4225
DETHHX448_03140
CAUCaur_0376
CHLChy400_0402
TROtrd_1806
PMETG4Y79_12490
SPSCE2P86_04415
EFALFH779_05715
CIVIMZ16_00275
CHYDH4K34_00830
HTUHtur_3820
MEUZKRP56_04315
CSUCSUB_C1174
 » show all
Reference
1  [PMID:13673006]
  Authors
LEVY HR, TALALAY P.
  Title
Bacterial oxidation of steroids. II. Studies on the enzymatic mechanism of ring A dehydrogenation.
  Journal
J Biol Chem 234:2014-21 (1959)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.99.4
IUBMB Enzyme Nomenclature: 1.3.99.4
ExPASy - ENZYME nomenclature database: 1.3.99.4
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.99.4
BRENDA, the Enzyme Database: 1.3.99.4
CAS: 9029-04-3

KEGG   REACTION: R09884
Entry
R09884                      Reaction                               
Name
androstenedione:acceptor Delta1-oxidoreductase
Definition
Androstenedione + Acceptor <=> Androsta-1,4-diene-3,17-dione + Reduced acceptor
Equation
Reaction class
RC00991  C00280_C20144
Enzyme
Pathway
rn00984  Steroid degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K05898  3-oxosteroid 1-dehydrogenase [EC:1.3.99.4]
Other DBs
RHEA: 51059

DBGET integrated database retrieval system