KEGG   ORTHOLOGY: K06637
Entry
K06637                      KO                                     

Symbol
BUB1B, BUBR1, MAD3L
Name
mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
Pathway
map04110  Cell cycle
map05166  Human T-cell leukemia virus 1 infection
Disease
H01288  Mosaic variegated aneuploidy syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  BUB family
   K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Genes
HSA: 701(BUB1B)
PTR: 453324(BUB1B)
PPS: 100970272(BUB1B)
GGO: 101145178(BUB1B)
PON: 100455824(BUB1B)
NLE: 100607252(BUB1B)
MCC: 100423079(BUB1B)
MCF: 102133579(BUB1B)
CSAB: 103245845(BUB1B)
CATY: 105574259(BUB1B)
PANU: 101009307(BUB1B)
RRO: 104659672(BUB1B)
RBB: 108526889(BUB1B)
TFN: 117070876(BUB1B)
PTEH: 111524256(BUB1B)
CJC: 100413586(BUB1B)
SBQ: 101052819(BUB1B)
MMUR: 105872430(BUB1B)
MMU: 12236(Bub1b)
MCAL: 110284043(Bub1b)
MPAH: 110318363(Bub1b)
RNO: 171576(Bub1b)
MCOC: 116090691(Bub1b)
MUN: 110566837(Bub1b)
CGE: 100754771
PLEU: 114705912(Bub1b)
NGI: 103741499(Bub1b)
HGL: 101705847(Bub1b)
OCU: 100349688(BUB1B)
TUP: 102493876(BUB1B)
CFA: 608350(BUB1B)
VVP: 112919939(BUB1B)
VLG: 121484782(BUB1B)
AML: 100464546(BUB1B)
UMR: 103673467(BUB1B)
UAH: 113242041(BUB1B)
ORO: 101373720(BUB1B)
ELK: 111140380
MPUF: 101671914(BUB1B)
EJU: 114221352(BUB1B)
MLX: 118003216(BUB1B)
PYU: 121042064(BUB1B)
PBG: 122468784(BUB1B)
PTG: 102972649(BUB1B)
PPAD: 109262594(BUB1B)
AJU: 106968546(BUB1B)
HHV: 120232293(BUB1B)
BTA: 537027(BUB1B)
BOM: 102274816(BUB1B)
BIU: 109564922(BUB1B)
BBUB: 102416300(BUB1B)
CHX: 102176047(BUB1B)
OAS: 101108313(BUB1B)
ODA: 120853220(BUB1B)
CCAD: 122443380(BUB1B)
SSC: 102164975(BUB1B)
CFR: 102521363(BUB1B)
CBAI: 105076892(BUB1B)
CDK: 105096887(BUB1B)
BACU: 103016990(BUB1B)
LVE: 103079417(BUB1B)
OOR: 101282086(BUB1B)
DLE: 111181757(BUB1B)
PCAD: 102985069(BUB1B)
ECB: 100629735(BUB1B)
EPZ: 103561630(BUB1B)
EAI: 106835169(BUB1B)
MYB: 102253751(BUB1B)
MYD: 102756936(BUB1B)
MMYO: 118649734(BUB1B)
MNA: 107543005(BUB1B)
HAI: 109383975(BUB1B)
DRO: 112311444(BUB1B)
SHON: 118993598(BUB1B)
AJM: 119061304(BUB1B)
MMF: 118634820(BUB1B)
PALE: 102896980(BUB1B)
PGIG: 120587191(BUB1B)
RAY: 107514461(BUB1B)
MJV: 108401648
TOD: 119238482(BUB1B)
LAV: 100668287(BUB1B)
TMU: 101346237
OAA: 100084747(BUB1B)
GGA: 378922(BUB1B)
PCOC: 116237837(BUB1B)
MGP: 100543305
CJO: 107314246(BUB1B)
NMEL: 110401707(BUB1B)
APLA: 101790286(BUB1B)
ACYG: 106047065(BUB1B)
TGU: 100232557(BUB1B)
LSR: 110485065(BUB1B)
SCAN: 103822308(BUB1B)
PMOA: 120500971(BUB1B)
GFR: 102045196(BUB1B)
FAB: 101822055(BUB1B)
PHI: 102102959(BUB1B)
PMAJ: 107205325(BUB1B)
CCAE: 111930493(BUB1B)
CCW: 104692976(BUB1B)
ETL: 114067937(BUB1B)
FPG: 101911948(BUB1B)
FCH: 102047575(BUB1B)
CLV: 102096269(BUB1B)
EGZ: 104131362(BUB1B)
NNI: 104020527(BUB1B)
ACUN: 113481007(BUB1B)
PADL: 103925168(BUB1B)
AAM: 106486730(BUB1B)
AROW: 112969663(BUB1B)
NPD: 112952072(BUB1B)
DNE: 112989500(BUB1B)
ASN: 102376270(BUB1B)
AMJ: 102573314(BUB1B)
CPOO: 109321486(BUB1B)
GGN: 109298734(BUB1B)
PSS: 102459964(BUB1B)
CMY: 102930824(BUB1B)
CPIC: 101953667(BUB1B)
TST: 117876712(BUB1B)
CABI: 116837812(BUB1B)
ACS: 100551949(bub1b)
PGUT: 117665696(BUB1B)
ZVI: 118083023(BUB1B)
GJA: 107119644(BUB1B)
XLA: 378923(bub1b.L)
XTR: 100125106(bub1b)
NPR: 108789285(BUB1B)
DRE: 567006(bub1bb)
SRX: 107726582
SANH: 107663167 107678768(bub1b)
CCAR: 109055584
CAUA: 113117807
IPU: 108269626(bub1b)
PHYP: 113538618(bub1b)
AMEX: 103035444(bub1b)
EEE: 113571360(bub1b)
TRU: 101076711(bub1b)
LCO: 104924801(bub1b)
NCC: 104953742(bub1b)
MSAM: 119910356(bub1bb)
MZE: 101474622(bub1b)
ONL: 100706285(bub1b)
OAU: 116322284(bub1bb)
OLA: 100820727(bub1b)
OML: 112141506(bub1bb)
XMA: 102231436(bub1b)
XCO: 114134078(bub1b)
XHE: 116708858(bub1b)
PRET: 103458557(bub1b)
CVG: 107094351(bub1b)
NFU: 107392480(bub1b)
KMR: 108234189(bub1bb)
ALIM: 106519848(bub1b)
AOCE: 111578032
CSEM: 103389571(bub1b)
POV: 109628147(bub1b)
LCF: 108892586(bub1b)
SDU: 111225862(bub1b)
SLAL: 111652451(bub1b)
XGL: 120795511(bub1bb)
HCQ: 109516066(bub1b)
BPEC: 110155400(bub1b)
MALB: 109968322(bub1b)
SASA: 106582108
OTW: 112261851
OMY: 110497980(bub1bb) 110529349
SALP: 111968788
SNH: 120024182
ELS: 105015642(bub1b)
SFM: 108919506(bub1b)
PKI: 111838880(bub1b)
AANG: 118207288(bub1bb)
LOC: 102691087(bub1b)
PSPA: 121329501
ARUT: 117418591(bub1bb) 117422654
BFO: 118425548
NLU: 111048718
DMK: 116928359
HAME: 121878405
HAZT: 108665736
EAF: 111711381
DSV: 119458661
RSAN: 119383899
VDE: 111242989
VJA: 111260345
SDM: 118192438
BGT: 106067972
PMAX: 117318644
NVE: 5498620
ATEN: 116303805
HMG: 100211978
 » show all
Reference
  Authors
Shin HJ, Baek KH, Jeon AH, Park MT, Lee SJ, Kang CM, Lee HS, Yoo SH, Chung DH, Sung YC, McKeon F, Lee CW
  Title
Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability.
  Journal
Cancer Cell 4:483-97 (2003)
DOI:10.1016/S1535-6108(03)00302-7
  Sequence
[hsa:701]
Reference
PMID:9618306
  Authors
Donadelli R, Benatti L, Remuzzi A, Morigi M, Gullans SR, Benigni A, Remuzzi G, Noris M
  Title
Identification of a novel gene--SSK1--in human endothelial cells exposed to shear stress.
  Journal
Biochem Biophys Res Commun 246:881-7 (1998)
DOI:10.1006/bbrc.1998.8713
  Sequence
[hsa:701]

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