K06645                      KO                                     

M-phase inducer phosphatase 1 [EC:]
map04110  Cell cycle
map04218  Cellular senescence
map04914  Progesterone-mediated oocyte maturation
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06645  CDC25A; M-phase inducer phosphatase 1
   04218 Cellular senescence
    K06645  CDC25A; M-phase inducer phosphatase 1
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K06645  CDC25A; M-phase inducer phosphatase 1
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K06645  CDC25A; M-phase inducer phosphatase 1
   05207 Chemical carcinogenesis - receptor activation
    K06645  CDC25A; M-phase inducer phosphatase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K06645  CDC25A; M-phase inducer phosphatase 1
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06645  CDC25A; M-phase inducer phosphatase 1
   03400 DNA repair and recombination proteins
    K06645  CDC25A; M-phase inducer phosphatase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases  protein-tyrosine-phosphatase
     K06645  CDC25A; M-phase inducer phosphatase 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein tyrosine phosphatases (PTPs)
  Class III PTPs
    K06645  CDC25A; M-phase inducer phosphatase 1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     K06645  CDC25A; M-phase inducer phosphatase 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    K06645  CDC25A; M-phase inducer phosphatase 1
Other DBs
GO: 0004725
HSA: 993(CDC25A)
PTR: 460341(CDC25A)
PPS: 100985899(CDC25A)
GGO: 101142222(CDC25A)
PON: 100460228(CDC25A)
NLE: 100588003(CDC25A)
MCC: 710858(CDC25A)
MCF: 102137696(CDC25A)
CSAB: 103228635(CDC25A)
CATY: 105573640(CDC25A)
PANU: 101017438(CDC25A)
RRO: 104671299(CDC25A)
RBB: 108517663(CDC25A)
TFN: 117080687(CDC25A)
PTEH: 111555493(CDC25A)
CJC: 100408832(CDC25A)
SBQ: 101041208(CDC25A)
MMUR: 105874913(CDC25A)
MMU: 12530(Cdc25a)
MCAL: 110301556(Cdc25a)
MPAH: 110327415(Cdc25a)
RNO: 171102(Cdc25a)
MCOC: 116072801(Cdc25a)
MUN: 110565748(Cdc25a)
CGE: 100767961(Cdc25a)
PLEU: 114705236(Cdc25a)
NGI: 103750230(Cdc25a)
HGL: 101699133(Cdc25a)
CCAN: 109699005(Cdc25a)
OCU: 100354280(CDC25A)
TUP: 102482369(CDC25A)
CFA: 484780(CDC25A)
VVP: 112912171(CDC25A)
VLG: 121494228(CDC25A)
AML: 100477247(CDC25A)
UMR: 103675112(CDC25A)
UAH: 113256823(CDC25A)
ORO: 101369809(CDC25A)
ELK: 111144080
MPUF: 101680806(CDC25A)
EJU: 114225128(CDC25A)
MLX: 118005263(CDC25A)
FCA: 101098445(CDC25A)
PYU: 121011146(CDC25A)
PTG: 102957057(CDC25A)
PPAD: 109247747(CDC25A)
AJU: 106979176(CDC25A)
HHV: 120229362(CDC25A)
BTA: 520188(CDC25A)
BOM: 102285046(CDC25A)
BIU: 109576463(CDC25A)
BBUB: 102415490(CDC25A)
CHX: 102181731(CDC25A)
OAS: 101113178(CDC25A)
ODA: 120868201(CDC25A)
CCAD: 122424249(CDC25A)
SSC: 100737380(CDC25A)
CFR: 102509600(CDC25A)
CBAI: 105083373(CDC25A)
CDK: 105103857(CDC25A)
BACU: 103016547(CDC25A)
LVE: 103085456(CDC25A)
OOR: 101282274(CDC25A)
DLE: 111174440(CDC25A)
PCAD: 102992519(CDC25A)
ECB: 100064223(CDC25A)
EPZ: 103567910(CDC25A)
EAI: 106821782(CDC25A)
MYD: 102760761(CDC25A)
MMYO: 118668522(CDC25A)
MNA: 107529418(CDC25A)
HAI: 109375294(CDC25A)
DRO: 112309765(CDC25A)
SHON: 118976202(CDC25A)
AJM: 119038075(CDC25A)
MMF: 118633065(CDC25A)
PALE: 102897196(CDC25A)
PGIG: 120582298(CDC25A)
RAY: 107513304(CDC25A)
MJV: 108402658(CDC25A)
TOD: 119259478(CDC25A)
LAV: 100659991(CDC25A)
TMU: 101346532
MDO: 100018150(CDC25A)
SHR: 100924467(CDC25A)
PCW: 110217106(CDC25A)
OAA: 100085311(CDC25A)
GGA: 420375(CDC25A)
PCOC: 116238507(CDC25A)
MGP: 100546502(CDC25A)
CJO: 107308656(CDC25A)
NMEL: 110390717(CDC25A)
APLA: 101800901(CDC25A)
ACYG: 106046801(CDC25A)
TGU: 100231363(CDC25A)
SCAN: 103813021(CDC25A)
PMOA: 120510615(CDC25A)
GFR: 102040683(CDC25A)
FAB: 101816817(CDC25A)
PHI: 102104005(CDC25A)
PMAJ: 107201060(CDC25A)
CCAE: 111925581(CDC25A)
CCW: 104686374(CDC25A)
ETL: 114069284(CDC25A)
FPG: 101911899(CDC25A)
FCH: 102054923(CDC25A)
CLV: 102084553(CDC25A)
EGZ: 104121808(CDC25A)
NNI: 104019237(CDC25A)
ACUN: 113476811(CDC25A)
PADL: 103916196(CDC25A)
AAM: 106499367
NPD: 112951558(CDC25A)
ASN: 102384816(CDC25A)
AMJ: 102569214(CDC25A)
CPOO: 109305787(CDC25A)
GGN: 109291133(CDC25A)
PSS: 102458852(CDC25A)
CMY: 102931776(CDC25A)
CPIC: 101944298(CDC25A)
TST: 117871895(CDC25A)
CABI: 116828404(CDC25A)
ACS: 100558641(cdc25a) 103280245
PVT: 110082540(CDC25A)
PBI: 103059140(CDC25A)
TSR: 106549893(CDC25A)
PGUT: 117673238
PMUA: 114607182(CDC25A)
ZVI: 118092194
GJA: 107124887(CDC25A)
XLA: 398141(cdc25a.L) 734734(cdc25a.S)
XTR: 733851(cdc25a)
NPR: 108800705
HHAL: 106685042
VDE: 111245511
VJA: 111260799
GAE: 121382917
 » show all
Galaktionov K, Beach D
Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins.
Cell 67:1181-94 (1991)
Karlsson-Rosenthal C, Millar JB
Cdc25: mechanisms of checkpoint inhibition and recovery.
Trends Cell Biol 16:285-92 (2006)
Hong HY, Choi J, Cho YW, Kim BC
Cdc25A promotes cell survival by stimulating NF-kappaB activity through IkappaB-alpha phosphorylation and destabilization.
Biochem Biophys Res Commun 420:293-6 (2012)

DBGET integrated database retrieval system