KEGG   ORTHOLOGY: K07408
Entry
K07408                      KO                                     
Symbol
CYP1A1
Name
cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00380  Tryptophan metabolism
map00830  Retinol metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map01100  Metabolic pathways
map04913  Ovarian steroidogenesis
map05204  Chemical carcinogenesis - DNA adducts
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
   05207 Chemical carcinogenesis - receptor activation
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
   05208 Chemical carcinogenesis - reactive oxygen species
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP1 family
   K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Other DBs
RN: R02354 R02355 R03089 R03408 R03629 R07000 R07001 R07021 R07022 R07079 R07080 R07081 R07085 R07087 R07098 R07099 R08390 R08392 R09418 R09423 R09442
Genes
HSA: 1543(CYP1A1)
PTR: 453744(CYP1A1)
PPS: 100976184(CYP1A1)
GGO: 101129522
PON: 100457153
NLE: 100585507
MCC: 678694(CYP1A1)
MCF: 102129994(CYP1A1)
CSAB: 103245331(CYP1A1)
CATY: 105600061
PANU: 101001307
TGE: 112627760
RRO: 104672151
RBB: 108531476
TFN: 117070364
PTEH: 111529702
CJC: 100393083(CYP1A1)
SBQ: 101038217
CSYR: 103271646
MMUR: 105854864
OGA: 100955410
MMU: 13076(Cyp1a1)
MCAL: 110301270
MPAH: 110328033
RNO: 24296(Cyp1a1)
MCOC: 116071961
MUN: 110558545
CGE: 100751269
MAUA: 101844540
PLEU: 114690337
MORG: 121445349
NGI: 103736921
HGL: 101707509
CPOC: 100135512(Cyp1a1)
CCAN: 109701505
DORD: 105982352
DSP: 122098438
NCAR: 124977051
OCU: 100328613(CYP1A1)
OPI: 101533768
TUP: 102484009
CFA: 100686778(CYP1A1)
VVP: 112908776
VLG: 121484958
AML: 100473028
UMR: 103678992
UAH: 113240972
UAR: 123790682
ELK: 111153267
LLV: 125105138
MPUF: 101676222
ORO: 101382250
EJU: 114206471
ZCA: 113910089
MLX: 118003748
FCA: 554347(CYP1A1)
PYU: 121041992
PBG: 122468425
PTG: 102966263
PPAD: 109262691
AJU: 106979443
HHV: 120235772
BTA: 282870(CYP1A1)
BOM: 102283235
BIU: 109575587
BBUB: 102399021
CHX: 102170823
OAS: 100170113(CYP1A1)
ODA: 120875451
CCAD: 122419730
SSC: 403103(CYP1A1)
CFR: 102518111
CBAI: 105069192
CDK: 105087262
VPC: 102530468
BACU: 103008057
LVE: 103071513
OOR: 101287158
DLE: 111177818
PCAD: 102984326
PSIU: 116749907
ECB: 100062285(CYP1A1)
EPZ: 103552317
EAI: 106831264
MYB: 102262349
MYD: 102762200
MMYO: 118675915
MLF: 102437172
MNA: 107535216
PKL: 118728867
HAI: 109396247
DRO: 112301821
SHON: 118987754
PDIC: 114492343
PHAS: 123825280
MMF: 118643668
RFQ: 117024155
PALE: 102892046
PGIG: 120597850
PVP: 105306836
RAY: 107510533
MJV: 108388606
TOD: 119237890
SARA: 101550604
LAV: 100665901
TMU: 101359275
DNM: 101423437
MDO: 100029871
GAS: 123232970
SHR: 100927711
PCW: 110213927
OAA: 100080942(CYP1A1)
ZVI: 118084457
STOW: 125424760
BBEL: 109480286
GAE: 121368990
CRG: 105329067
 » show all
Reference
PMID:2989797
  Authors
Jaiswal AK, Gonzalez FJ, Nebert DW
  Title
Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism.
  Journal
Nucleic Acids Res 13:4503-20 (1985)
DOI:10.1093/nar/13.12.4503
  Sequence
[hsa:1543]
Reference
PMID:3019683
  Authors
Kawajiri K, Watanabe J, Gotoh O, Tagashira Y, Sogawa K, Fujii-Kuriyama Y
  Title
Structure and drug inducibility of the human cytochrome P-450c gene.
  Journal
Eur J Biochem 159:219-25 (1986)
DOI:10.1111/j.1432-1033.1986.tb09857.x
  Sequence
[hsa:1543]

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