KEGG   ORTHOLOGY: K07418
Entry
K07418                      KO                                     
Symbol
CYP2J
Name
cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
Pathway
map00590  Arachidonic acid metabolism
map00591  Linoleic acid metabolism
map01100  Metabolic pathways
map04726  Serotonergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04913  Ovarian steroidogenesis
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
   00591 Linoleic acid metabolism
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
  09156 Nervous system
   04726 Serotonergic synapse
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
    1.14.14.73  albendazole monooxygenase (sulfoxide-forming)
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
    1.14.14.74  albendazole monooxygenase (hydroxylating)
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
    1.14.14.75  fenbendazole monooxygenase (4'-hydroxylating)
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07418  CYP2J; cytochrome P450 family 2 subfamily J
Other DBs
RN: R07042 R07043 R07044 R07045 R07046 R07048 R07050 R07051 R07052 R07055 R07056
Genes
HSA: 1573(CYP2J2)
PTR: 456896(CYP2J2)
PPS: 100984148(CYP2J2)
GGO: 101148349
PON: 100447634
NLE: 100589053
MCC: 693631
MCF: 102119662(CYP2J2)
MTHB: 126962785
CSAB: 103224719(CYP2J2)
CATY: 105595967
TGE: 112630798
RRO: 104668045
RBB: 108532916
TFN: 117091994
PTEH: 111522986
CJC: 100397287(CYP2J2)
SBQ: 101041470
CSYR: 103256114
MMU: 100066(Cyp2j11) 13109(Cyp2j5) 13110(Cyp2j6) 230459(Cyp2j13) 242546(Cyp2j12) 665095(Cyp2j8) 74519(Cyp2j9)
RNO: 100912642 313373(Cyp2j10) 313375(Cyp2j3) 502969(Cyp2j16) 65210(Cyp2j4)
CCAN: 109684284
NCAR: 124966849
OCU: 100301544(CYP2J1)
GVR: 103603536
CFA: 610195(CYP2J2)
CLUD: 112647122
VVP: 112926087
VLG: 121499260
AML: 100482335
UMR: 103663082
UAH: 113254606
UAR: 123795371
ELK: 111143525
LLV: 125097704
MPUF: 101684683
ORO: 101382939
EJU: 114212028
ZCA: 113926705
MLX: 118020215
NSU: 110571781
LWW: 102747983
FCA: 101097746
PYU: 121027220
PBG: 122480573
LRUF: 124516300
PTG: 102958105
PPAD: 109266776
AJU: 106974984
HHV: 120236077
LVE: 103072875
OOR: 101287985
DLE: 111175878
PCAD: 102995526
PSIU: 116764420
ECB: 100067247
EPZ: 103564165
EAI: 106833456
MYB: 102259820
MYD: 102765527
MMYO: 118676695
MLF: 102439141
MNA: 107531748
AJM: 119042498
MMF: 118627182
PALE: 102885276
PGIG: 120621913
PVP: 105303444
RAY: 107518358
TMU: 101350163
OAA: 100087745
GGA: 101750603(CYP2J21) 424676(CYP2J23) 424677(CYP2J22) 424729(CYP2J19)
TGU: 100224220(CYP2J40) 100230439(CYP2J19A)
SCAN: 103815060 103815209(CYP2J19)
ETL: 114069063
ZAB: 102067922
ACHL: 103807106
FPG: 101919387
PCRI: 104028699
CCRI: 104159712
PGUU: 104462916
ACAR: 104520204
AVIT: 104278846
CVF: 104285547
BRHI: 104488759
AMJ: 102557714(CYP2P10)
CPOO: 109307018
GGN: 109305297
CMY: 102936353 102940076(CYP2J19)
TST: 117882110
CABI: 116833772
ACS: 100567522
DRE: 100034366(cyp2p8) 100034406(cyp2p7) 393108(cyp2p6) 393592(cyp2p9) 399485(cyp2p10) 797309(cyp2j20)
SRX: 107737305
SANH: 107665313
AMEX: 103037239
TRU: 101075700
CGOB: 115007060
SLUC: 116063278
ECRA: 117950841
PFLV: 114560939
PPUG: 119216714
OLA: 100302452(cyp2p3) 105353996
CSEM: 103383190
POV: 109625616
HSP: 118121284
BPEC: 110173990
SASA: 106584062
OTW: 112250281
OMY: 110521776
OGO: 124038052
ONE: 115145370
SALP: 111971193
SNH: 120052641
CCLU: 121533858
ELS: 105025359
CMK: 103185273
RTP: 109921744
BCOO: 119083310
PVM: 113807691
VDE: 111244479
VJA: 111272117
XEN: 124445682
 » show all
Reference
PMID:1717443 (CYP2J1)
  Authors
Kikuta Y, Sogawa K, Haniu M, Kinosaki M, Kusunose E, Nojima Y, Yamamoto S, Ichihara K, Kusunose M, Fujii-Kuriyama Y
  Title
A novel species of cytochrome P-450 (P-450ib) specific for the small intestine of rabbits. cDNA cloning and its expression in COS cells.
  Journal
J Biol Chem 266:17821-5 (1991)
  Sequence
[ocu:100301544]
Reference
PMID:8631948 (CYP2J2)
  Authors
Wu S, Moomaw CR, Tomer KB, Falck JR, Zeldin DC
  Title
Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart.
  Journal
J Biol Chem 271:3460-8 (1996)
DOI:10.1074/jbc.271.7.3460
  Sequence
[hsa:1573]
Reference
PMID:9139707 (CYP2J3)
  Authors
Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR, Zeldin DC
  Title
Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes.
  Journal
J Biol Chem 272:12551-9 (1997)
DOI:10.1074/jbc.272.19.12551
  Sequence
[rno:313375]
Reference
PMID:9570962 (CYP2J5)
  Authors
Ma J, Ramachandran S, Fiedorek FT Jr, Zeldin DC
  Title
Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4.
  Journal
Genomics 49:152-5 (1998)
DOI:10.1006/geno.1998.5235
  Sequence
[mmu:13109]
Reference
  Authors
Scarborough PE, Ma J, Qu W, Zeldin DC
  Title
P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues.
  Journal
Drug Metab Rev 31:205-34 (1999)
DOI:10.1081/DMR-100101915

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