KEGG   ORTHOLOGY: K08525
Entry
K08525                      KO                                     

Symbol
RXRB, NR2B2
Name
retinoid X receptor beta
Pathway
map03320  PPAR signaling pathway
map04659  Th17 cell differentiation
map04919  Thyroid hormone signaling pathway
map04920  Adipocytokine signaling pathway
map04928  Parathyroid hormone synthesis, secretion and action
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
map05207  Chemical carcinogenesis - receptor activation
map05216  Thyroid cancer
map05222  Small cell lung cancer
map05223  Non-small cell lung cancer
map05226  Gastric cancer
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K08525  RXRB, NR2B2; retinoid X receptor beta
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   03320 PPAR signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   04919 Thyroid hormone signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   04928 Parathyroid hormone synthesis, secretion and action
    K08525  RXRB, NR2B2; retinoid X receptor beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05202 Transcriptional misregulation in cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05207 Chemical carcinogenesis - receptor activation
    K08525  RXRB, NR2B2; retinoid X receptor beta
  09162 Cancer: specific types
   05226 Gastric cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05216 Thyroid cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05222 Small cell lung cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05223 Non-small cell lung cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K08525  RXRB, NR2B2; retinoid X receptor beta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08525  RXRB, NR2B2; retinoid X receptor beta
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08525  RXRB, NR2B2; retinoid X receptor beta
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    K08525  RXRB, NR2B2; retinoid X receptor beta
Nuclear receptors [BR:ko03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   K08525  RXRB, NR2B2; retinoid X receptor beta
Other DBs
GO: 0004886
Genes
HSA: 6257(RXRB)
PTR: 462601(RXRB)
PPS: 100992933(RXRB)
GGO: 101143109(RXRB)
PON: 100460920(RXRB)
NLE: 100580742(RXRB)
MCC: 717368(RXRB)
MCF: 102132522(RXRB)
CSAB: 103221675(RXRB)
CATY: 105593512(RXRB)
PANU: 101021005(RXRB)
RRO: 104657982(RXRB)
RBB: 108540287(RXRB)
TFN: 117087032(RXRB)
PTEH: 111542907(RXRB)
CJC: 100414004(RXRB)
SBQ: 101040304(RXRB)
MMUR: 105885999(RXRB)
MMU: 20182(Rxrb)
MCAL: 110312146(Rxrb)
MPAH: 110335436(Rxrb)
RNO: 361801(Rxrb)
MCOC: 116074254(Rxrb)
MUN: 110543383(Rxrb)
CGE: 100759059(Rxrb)
PLEU: 114686359(Rxrb)
NGI: 103739713(Rxrb)
HGL: 101723696(Rxrb)
CCAN: 109686703(Rxrb)
OCU: 100354287(RXRB)
TUP: 102495243(RXRB)
CFA: 481735(RXRB)
VVP: 112913873(RXRB)
VLG: 121498240(RXRB)
AML: 100475696(RXRB)
UMR: 103665560(RXRB)
UAH: 113243791(RXRB)
ORO: 101373938(RXRB)
ELK: 111152195
MPUF: 101679943(RXRB)
EJU: 114222159(RXRB)
MLX: 118001622(RXRB)
PTG: 102952674(RXRB)
PPAD: 109271425(RXRB)
AJU: 106976118(RXRB)
HHV: 120238152(RXRB)
BTA: 504943(RXRB)
BOM: 102286075(RXRB)
BIU: 109576548(RXRB)
BBUB: 102408491(RXRB)
CHX: 102189445(RXRB)
OAS: 101110798(RXRB)
ODA: 120869850(RXRB)
SSC: 100156801(RXRB)
CFR: 102517692(RXRB)
CBAI: 105064232(RXRB)
CDK: 105101393(RXRB)
BACU: 103006710(RXRB)
LVE: 103087387(RXRB)
OOR: 101287304(RXRB)
DLE: 111178670(RXRB)
PCAD: 102973179(RXRB)
ECB: 100061303(RXRB)
EPZ: 103541179(RXRB)
EAI: 106834605(RXRB)
MYB: 102247746(RXRB)
MYD: 102766946(RXRB)
MMYO: 118679517(RXRB)
MNA: 107542678(RXRB)
HAI: 109392460(RXRB)
DRO: 112302171(RXRB)
SHON: 118991475(RXRB)
AJM: 119041210(RXRB)
MMF: 118621531(RXRB)
PALE: 102888877(RXRB)
PGIG: 120597645(RXRB)
RAY: 107511984(RXRB)
MJV: 108396293(RXRB)
TOD: 119252328(RXRB)
LAV: 100662699(RXRB)
TMU: 101349083
MDO: 100027006(RXRB)
SHR: 100914649(RXRB)
PCW: 110199336(RXRB)
LSR: 110480012(RXRB)
ETL: 114072199
ASN: 102369321(RXRB)
AMJ: 102561414(RXRB)
CPOO: 109314098
CMY: 102930075(RXRB)
CPIC: 101936256
CABI: 116829511(RXRB)
ACS: 100554139
PVT: 110091139(RXRB)
PBI: 103055088(RXRB)
TSR: 106553505
PGUT: 117673475(RXRB)
PMUA: 114592592(RXRB)
ZVI: 118081294(RXRB)
GJA: 107109601(RXRB)
XLA: 394278(rxrb.L) 398075(rxrb.S)
XTR: 548691(rxrb)
NPR: 108788389(RXRB)
DRE: 30530(rxrba)
SGH: 107566635
IPU: 108272672
PHYP: 113535174
AMEX: 103021434
EEE: 113591253
TRU: 101065480
LCO: 104933394
NCC: 104957485(rxrb)
CGOB: 115015525
ELY: 117263089(rxrba)
PLEP: 121957769(rxrba)
SLUC: 116047048(rxrba)
ECRA: 117956557(rxrba)
PFLV: 114567531
GAT: 120826162(rxrba)
MSAM: 119907963(rxrba)
CUD: 121524445(rxrba)
MZE: 101473908
ONL: 100534499
OAU: 116310856(rxrba)
OLA: 100125505
OML: 112161753(rxrba)
XMA: 102217951
XCO: 114156477
XHE: 116730543
PRET: 103472931
CTUL: 119795019(rxrba)
NFU: 107378676 107394848(rxrb)
KMR: 108241994(rxrbb) 108242661(rxrba)
ALIM: 106517732 106519580(rxrb)
AOCE: 111584592
CSEM: 103393870
POV: 109641308
LCF: 108886934
SDU: 111239434
SLAL: 111661213
XGL: 120786101(rxrba)
HCQ: 109514591
BPEC: 110173337
MALB: 109952506
SASA: 106569952 106588394(RXRB)
ELS: 105005656(rxrb) 105018834
SFM: 108935649(rxrb)
PKI: 111835653
LCM: 102350929
NVE: 5511614
AQU: 100616090
 » show all
Reference
PMID:1310259
  Authors
Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen JY, Staub A, Garnier JM, Mader S, et al.
  Title
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.
  Journal
Cell 68:377-95 (1992)
DOI:10.1016/0092-8674(92)90478-U
  Sequence
[hsa:6257]
Reference
  Authors
Lefebvre P, Benomar Y, Staels B
  Title
Retinoid X receptors: common heterodimerization partners with distinct functions.
  Journal
Trends Endocrinol Metab 21:676-83 (2010)
DOI:10.1016/j.tem.2010.06.009

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