KEGG   ORTHOLOGY: K10224
Entry
K10224                      KO                                     
Symbol
FADS1
Name
acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]
Pathway
map01040  Biosynthesis of unsaturated fatty acids
map01100  Metabolic pathways
map01212  Fatty acid metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   01040 Biosynthesis of unsaturated fatty acids
    K10224  FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10224  FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.44  acyl-CoA (8-3)-desaturase
     K10224  FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase)
Lipid biosynthesis proteins [BR:ko01004]
 Desaturase
  Front-end
   K10224  FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase)
Other DBs
RN: R11059 R11060 R12169
Genes
HSA: 3992(FADS1)
PTR: 451243(FADS1)
PPS: 100981162(FADS1)
GGO: 101136185(FADS1)
PON: 100436159(FADS1)
NLE: 100596120(FADS1)
MCC: 722343(FADS1)
MCF: 101864778(FADS1)
MTHB: 126935470
MNI: 105469425(FADS1)
CSAB: 103234224(FADS1)
CATY: 105577579(FADS1)
PANU: 100126707(FADS1)
TGE: 112606126(FADS1)
RRO: 104679375(FADS1)
RBB: 108533599(FADS1)
TFN: 117080259(FADS1)
PTEH: 111524317(FADS1)
CANG: 105512288(FADS1)
CJC: 100389579(FADS1)
SBQ: 101052172(FADS1)
MMUR: 105878618(FADS1)
LCAT: 123641269(FADS1)
PCOQ: 105825052(FADS1)
OGA: 100954652(FADS1)
MMU: 76267(Fads1)
MCAL: 110285897(Fads1)
MPAH: 110322451(Fads1)
RNO: 84575(Fads1)
MCOC: 116103544(Fads1)
MUN: 110548091(Fads1)
CGE: 100773095
MAUA: 101844332(Fads1)
PLEU: 114703435(Fads1)
MORG: 121453877(Fads1)
MFOT: 126498525
AAMP: 119813303(Fads1)
NGI: 103729124(Fads1)
HGL: 101698014(Fads1)
CPOC: 100723348(Fads1)
CCAN: 109685566(Fads1)
DORD: 105995514(Fads1)
DSP: 122104887(Fads1)
NCAR: 124958643
OCU: 100342403
OPI: 101524219(FADS1)
TUP: 102500595(FADS1)
GVR: 103604811(FADS1)
CFA: 483793(FADS1)
CLUD: 112659419(FADS1)
VVP: 112911088(FADS1)
VLG: 121472259(FADS1)
AML: 100472955(FADS1)
UMR: 103678230(FADS1)
UAH: 113246984(FADS1)
UAR: 123785000(FADS1)
ELK: 111149587
LLV: 125078519
MPUF: 101676081(FADS1)
NVS: 122912991(FADS1)
ORO: 101364825(FADS1)
EJU: 114220205(FADS1)
ZCA: 113914860(FADS1)
MLX: 118015924(FADS1)
NSU: 110576324(FADS1)
LWW: 102739160(FADS1)
FCA: 101083966(FADS1)
PYU: 121043898(FADS1)
PBG: 122483865(FADS1)
LRUF: 124505586
PTG: 102968608(FADS1)
PPAD: 109246555(FADS1)
AJU: 106986968(FADS1)
HHV: 120246150(FADS1)
BTA: 533107(FADS1)
BOM: 102276098(FADS1)
BIU: 109554369(FADS1)
BBUB: 102405648(FADS1)
BBIS: 104998703(FADS1)
CHX: 102178247(FADS1)
OAS: 101109049(FADS1)
ODA: 120874548(FADS1)
CCAD: 122431165(FADS1)
SSC: 444995(FADS1)
CFR: 102506763(FADS1)
CBAI: 105070110(FADS1)
CDK: 105094872(FADS1)
VPC: 102543424(FADS1)
BACU: 103008410(FADS1)
LVE: 103082696(FADS1)
OOR: 101275971(FADS1)
DLE: 111183884(FADS1)
PCAD: 102988776(FADS1)
PSIU: 116757880(FADS1)
ECB: 102150261(FADS1)
EPZ: 103543089(FADS1)
EAI: 106847567(FADS1)
MYB: 102261592(FADS1)
MYD: 102773181(FADS1)
MMYO: 118649002(FADS1)
MNA: 107527686(FADS1)
PKL: 118707199(FADS1)
HAI: 109390020(FADS1)
DRO: 112317234(FADS1)
SHON: 118996919(FADS1)
AJM: 119043682(FADS1)
PDIC: 114499452(FADS1)
PHAS: 123829519(FADS1)
MMF: 118627540(FADS1)
RFQ: 117030354(FADS1)
PALE: 102894313(FADS1)
PGIG: 120600651(FADS1)
PVP: 105297785(FADS1)
RAY: 107501590(FADS1)
MJV: 108392394(FADS1)
TOD: 119231397 119250072(FADS1)
SARA: 101540344(FADS1)
LAV: 100677495
TMU: 101347278
ETF: 101661682(FADS1)
DNM: 101417194(FADS1)
MDO: 100028492(FADS1)
SHR: 100922163(FADS1)
PCW: 110195308(FADS1)
OAA: 103171425(FADS1)
GGA: 423119(FADS1L2) 423120(FADS1) 428851(FADS1L1)
FCH: 102049758(FADS1) 106631119
OHA: 104339400 104339408(FADS1)
GGN: 109298190
CPIC: 101936861(FADS1) 101937159
XLA: 108713836(fads1.L) 108715199(fads1.S)
XTR: 100489232(fads1)
NPR: 108794178(FADS1)
RTEM: 120917259(FADS1)
BBUF: 120981188(FADS1)
BGAR: 122920198(FADS1)
AANG: 118215203
LOC: 102691516(fads1)
PSPA: 121330344
PSEX: 120535962
LCM: 102350226(FADS1)
CMK: 103174860
RTP: 109937249
AJC: 117125539
ATD: 109598043
PCAN: 112557826
 » show all
Reference
  Authors
Cho HP, Nakamura M, Clarke SD
  Title
Cloning, expression, and fatty acid regulation of the human delta-5 desaturase.
  Journal
J Biol Chem 274:37335-9 (1999)
DOI:10.1074/jbc.274.52.37335
  Sequence
[hsa:3992]

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