KEGG   ORTHOLOGY: K10258
Entry
K10258                      KO                                     
Symbol
TER, TSC13, CER10
Name
very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
Pathway
map00062  Fatty acid elongation
map01040  Biosynthesis of unsaturated fatty acids
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01212  Fatty acid metabolism
Module
M00415  Fatty acid elongation in endoplasmic reticulum
Disease
H00768  Autosomal recessive intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
   01040 Biosynthesis of unsaturated fatty acids
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.93  very-long-chain enoyl-CoA reductase
     K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Component type
   K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
Other DBs
RN: R07761 R09449 R10828
Genes
HSA: 9524(TECR)
PTR: 455786(TECR)
PPS: 100971383(TECR)
GGO: 109025468(TECR)
PON: 100440904(TECR)
NLE: 100581652(TECR)
MCC: 718928(TECR)
MCF: 101926702(TECR)
CSAB: 103234044(TECR)
CATY: 105601591(TECR)
PANU: 101026540(TECR)
TGE: 112613496(TECR)
RRO: 104661039(TECR)
RBB: 108514773(TECR)
TFN: 117076184(TECR)
PTEH: 111546248 111554381(TECR)
CJC: 100402213(TECR)
SBQ: 101033875(TECR)
CSYR: 103261896(TECR)
MMUR: 105867918(TECR)
LCAT: 123637858(TECR) 123638708
OGA: 100961670(TECR)
MMU: 106529(Tecr)
MCAL: 110300213(Tecr)
MPAH: 110337246(Tecr)
RNO: 191576(Tecr) 499018(RGD1560015)
MCOC: 116069683(Tecr)
MUN: 110545857(Tecr)
CGE: 100761652(Tecr)
MAUA: 101826283(Tecr)
PLEU: 114688224(Tecr)
MORG: 121455891(Tecr)
AAMP: 119801779(Tecr)
NGI: 103751841(Tecr)
HGL: 101716060(Tecr)
CPOC: 100714067(Tecr)
CCAN: 109686636(Tecr)
DORD: 105999261(Tecr)
DSP: 122119692(Tecr)
NCAR: 124968574
OPI: 101534989(TECR)
TUP: 102480210(TECR)
CFA: 476687(TECR)
CLUD: 112666635(TECR)
VVP: 112908161(TECR)
VLG: 121494403(TECR)
AML: 100467030(TECR) 117801863
UMR: 103682180(TECR)
UAH: 113247156(TECR)
UAR: 123801754(TECR)
ELK: 111162454
LLV: 125083500
MPUF: 101676388(TECR)
ORO: 101386071(TECR)
EJU: 114197645(TECR)
ZCA: 113916285(TECR)
MLX: 118005922(TECR)
FCA: 101091601(TECR)
PYU: 121024688(TECR)
PBG: 122486995(TECR)
PTG: 102959844(TECR)
PPAD: 109247758 109253922(TECR)
AJU: 106986213(TECR)
HHV: 120245260(TECR)
BTA: 614105(TECR)
BOM: 102285957(TECR)
BIU: 109561491(TECR)
BBUB: 102397352(TECR)
CHX: 102187120(TECR)
OAS: 101117331(TECR)
ODA: 120864104(TECR)
CCAD: 122440561(TECR)
SSC: 100515709(TECR)
CFR: 102519742(TECR)
CBAI: 105068292(TECR)
CDK: 105105973(TECR)
VPC: 102545694(TECR)
BACU: 102997227(TECR)
LVE: 103070891(TECR)
OOR: 101269817(TECR)
DLE: 111166579(TECR)
PCAD: 102975948(TECR)
PSIU: 116751802(TECR)
ECB: 100065024(TECR)
EPZ: 103565661(TECR)
EAI: 106844303(TECR)
MYB: 102260613(TECR)
MYD: 102751823(TECR)
MMYO: 118652703(TECR)
MLF: 102420692(TECR)
MNA: 107542369(TECR)
PKL: 118706496(TECR)
HAI: 109394266(TECR)
DRO: 112301386(TECR)
SHON: 118984073(TECR)
AJM: 119049699(TECR)
PDIC: 114502622(TECR)
PHAS: 123828267(TECR)
MMF: 118615910(TECR)
RFQ: 117037956(TECR)
PALE: 102887858(TECR)
PGIG: 120618471(TECR)
PVP: 105308511(TECR)
RAY: 107519419(TECR)
MJV: 108393978(TECR)
TOD: 119241043(TECR)
SARA: 101543878 101557823(TECR)
LAV: 100674918(TECR)
TMU: 101348735
DNM: 101439800(TECR)
MDO: 100026440(TECR) 100032861
GAS: 123242624(TECR)
SHR: 100914010(TECR) 116423386
PCW: 110197969 110203436(TECR)
OAA: 100080249 100081999(TECR)
GGA: 107050163 424491(TECR)
PCOC: 116238972(TECR) 116243504
MGP: 100545685(TECR)
CJO: 107317393
NMEL: 110402349(TECR)
APLA: 101799511(TECR)
ACYG: 106039444(TECR)
AFUL: 116491679(TECR)
TGU: 100230168
LSR: 110468229(TECR)
SCAN: 103815135(TECR)
GFR: 102032504(TECR)
FAB: 101810425(TECR)
PHI: 102099600(TECR) 106628096
PMAJ: 107208393
CCAE: 111922653(TECR) 111932652
CCW: 104695353(TECR)
CBRC: 103612775(TECR)
ETL: 114055627(TECR)
ZAB: 102066769(TECR)
FPG: 101910412
FCH: 102049843(TECR)
CLV: 110363827(TECR)
EGZ: 104134018(TECR)
NNI: 104015498
PLET: 104621069(TECR)
PCRI: 104025245(TECR)
ACUN: 113482866(TECR)
TALA: 104358085(TECR)
PADL: 103925113(TECR)
HALD: 104324182(TECR)
CCRI: 104161161(TECR)
CSTI: 104555420(TECR)
EHS: 104504550(TECR)
FGA: 104082968(TECR)
GSTE: 104261550(TECR)
LDI: 104344721(TECR)
MNB: 103781130
AAM: 106499774(TECR)
AROW: 112961864(TECR)
NPD: 112946229(TECR)
DNE: 112979796(TECR)
ASN: 102370679(TECR) 102383204
AMJ: 102559187(TECR) 102575131
CPOO: 109307274(TECR)
GGN: 109286852(TECR)
PSS: 102457301(TECR) 102459125
CMY: 102929357(TECR) 102931932
CPIC: 101937001(TECR) 101945886
TST: 117881252 117888503(TECR)
CABI: 116820507 116825406(TECR)
MRV: 120370281 120391408(TECR)
ACS: 100560578 100566730(tecr)
PVT: 110070802(TECR) 110076484
SUND: 121921198(TECR) 121928617
PBI: 103058993 103065171(TECR)
PMUR: 107292471(TECR) 107295608
TSR: 106543114(TECR)
PGUT: 117659321(TECR) 117677238
VKO: 123024554 123035425(TECR)
PMUA: 114590788(TECR) 114598728
ZVI: 118079968(TECR) 118088377
GJA: 107112228 107117643(TECR)
XLA: 108713542(MGC146850.L) 380153(tecr.L) 444160(tecr.S)
XTR: 493561(tecr) 780081(MGC146850)
NPR: 108789250 108797751(TECR)
RTEM: 120933242(TECR) 120945671
BBUF: 120978502 120986215(TECR)
DRE: 326954(tecrb) 450002(tecrl2b) 566085(tecra) 798606(tecrl2a)
MAMB: 125251117(tecrl2b) 125255757(tecra) 125258034(tecrl2a) 125278130(tecrb)
IPU: 100528865(tecrb) 108255190(tecrl2a) 108256782(tecra)
SMEO: 124376328(tecra) 124378407(tecrb) 124384339(tecrl2a) 124402984(tecrl2b)
TFD: 113636364(tecrb) 113649827(tecrl2a) 113655481(tecrl2b) 113661946(tecra)
ELY: 117255374(tecrb) 117264704 117268496(tecra)
EFO: 125879780(tecra) 125882307(tecrl2a) 125885560(tecrb)
PLEP: 121956431(tecra) 121960674
SLUC: 116042814(tecrb) 116055761 116059458(tecra)
ECRA: 117937872 117958745(tecra) 117959246(tecrb)
GAT: 120811678 120825752(tecrb) 120827143(tecra)
PPUG: 119198318 119217402(tecrb) 119220462(tecra)
MSAM: 119896514(tecra) 119899464(tecrb) 119907318
CUD: 121503681(tecra) 121508514(tecrb) 121527467
ALAT: 119008691 119013482(tecra) 119025994(tecrb)
OAU: 116310621(tecrb) 116317697(tecra) 116335763
OML: 112137470(tecrb) 112146832(tecra) 112151473
PRET: 103461133(tecr) 103482281
GAF: 122821457(tecra) 122824237(tecrl2a) 122829703(tecrb)
CTUL: 119794849(tecra) 119795985 119798025(tecrb)
GMU: 124857930(tecrl2a) 124862898 124864986 124868154(tecrb)
KMR: 108241336(tecra) 108241483(tecrb)
ALIM: 106529633 106530387(tecr)
NWH: 119421720(tecra) 119422775(tecrb)
MCEP: 124995889(tecrl2a) 124998441(tecra) 125003991(tecrb)
SSEN: 122771204(tecrb) 122772526(tecrl2a) 122785720(tecra)
HHIP: 117753845 117765698(tecra) 117769039(tecrb)
HSP: 118098778(tecrl2a) 118120502(tecrb) 118123350(tecra)
LCF: 108885426(tecr) 108902677
XGL: 120788205(tecra) 120789966 120800507(tecrb)
HCQ: 109521419 109527436(tecr)
MALB: 109952401(tecr) 109966006
BSPL: 114851837(tecrb) 114854026 114861094(tecra)
AANG: 118219786(tecrb) 118225720
LOC: 102686016 102686340(tecr)
RTP: 109916854(tecr)
BFO: 118431796
BBEL: 109486152
CIN: 100183960
SCLV: 120339053
APLC: 110985205
SKO: 100372208
DME: Dmel_CG10849(Sc2)
DER: 6546239
DSE: 6610677
DSI: Dsimw501_GD13786(Dsim_GD13786)
DAN: 6506865
DSR: 110183653
DPO: 4812074
DPE: 6601109
DMN: 108152677
DWI: 6643043
DGR: 6558720
DAZ: 108613041
DNV: 108652307
DHE: 111596861
DVI: 6636822
CCAT: 101451986
BOD: 106625933
MDE: 101887858
SCAC: 106088957
LCQ: 111684843
LSQ: 119614956
HIS: 119655714
ACOZ: 120955082
AARA: 120903293
ASTE: 118505333
AAG: 5570994
CPII: 120414909
CNS: 116351695
BCOO: 119072652
AME: 725146
ACER: 107996601
ALAB: 122714998
BIM: 100747299
BBIF: 117205321
BVK: 117238802
BVAN: 117157507
BTER: 100644169
BPYO: 122567664
CCAL: 108626760
OBB: 114875737
MGEN: 117218808
NMEA: 116427316
CGIG: 122399107
SOC: 105193039
MPHA: 105834618
AEC: 105153980
ACEP: 105618040
PBAR: 105433004
VEM: 105563404
HST: 105181228
DQU: 106746495
CFO: 105259215
FEX: 115242265
LHU: 105673344
PGC: 109859407
OBO: 105282481
PCF: 106791875
PFUC: 122522405
VPS: 122636487
NVI: 107980451
CSOL: 105366015
TPRE: 106647989
MDL: 103579818
CGLO: 123267621
FAS: 105268286
DAM: 107045802
AGIF: 122851250
CCIN: 107269001
TCA: 659815
DPA: 109537890
SOY: 115876726
ATD: 109608357
CSET: 123321790
AGB: 108907369
NVL: 108567063
APLN: 108740928
PPYR: 116166007
OTU: 111421540
BMOR: 101742899
MSEX: 115455791
BANY: 112049612
PMAC: 106718707
PPOT: 106100594
PXU: 106124851
PRAP: 110995799
ZCE: 119829437
HAW: 110375119
HZE: 124633678
TNL: 113496889
SLIU: 111353415
OFU: 114349809
PXY: 105385206
AGS: 114122650
RMD: 113560909
DCI: 103515585
CLEC: 106664306
HHAL: 106687828
FOC: 113210083
TPAL: 117642585
ZNE: 110835131
CSEC: 111863541
FCD: 110859769
DMK: 116917298
PVM: 113827755
PJA: 122251137
PCHN: 125025654
HAME: 121875625
PCLA: 123765086
PTRU: 123518808
HAZT: 108671836
LSM: 121119024
PPOI: 119098659
RSAN: 119405195
RMP: 119181189
VDE: 111245145
VJA: 111269559
TUT: 107369209
DFR: 124495727
CSCU: 111629930
PTEP: 107441461
SDM: 118182071
CEL: CELE_C15F1.6(art-1)
CBR: CBG_11196(Cbr-art-1)
TSP: Tsp_07269
PCAN: 112573754
BGT: 106077618
GAE: 121374304
HRF: 124135578
HRJ: 124260109
CRG: 105326706
MYI: 110461543
PMAX: 117326220
MMER: 123524742
OBI: 106878132
LAK: 106164649
EGL: EGR_03533
NVE: 5512326
EPA: 110241894
ATEN: 116291763
ADF: 107357184
AMIL: 114956483
PDAM: 113679514
SPIS: 111341682
DGT: 114526317
XEN: 124442083
HMG: 100209541
AQU: 100640363
ATH: AT3G55360(CER10)
ALY: 9312365
CRB: 17884738
BRP: 103841442
BOE: 106312603
RSZ: 108805403
THJ: 104810019
CIT: 102619239
PVY: 116117715
TCC: 18586099
EGR: 104454293
VRA: 106762967
VAR: 108337072
VUN: 114195412
CCAJ: 109795557
APRC: 113846884
CAM: 101508101(sr5a)
ADU: 107496735
AIP: 107609317
LANG: 109356796
FVE: 101313554
RCN: 112182703
PPER: 18784679
PMUM: 103332647
PAVI: 110756623
PDUL: 117617726
PXB: 103935366
ZJU: 107413483
MNT: 21394038
CSV: 101213758
CMO: 103498153
CPEP: 111808372
RCU: 8267764
JCU: 105647736
HBR: 110649118
QLO: 115957498
VVI: 100266766
VRI: 117929129
SLY: 101263911
SPEN: 107020319
SOT: 102581846
SSTN: 125867929
CANN: 107870238
NSY: 104222744
NTO: 104088381
NAU: 109240729
INI: 109186449
ITR: 116014001
SIND: 105171911
EGT: 105962734
SSPL: 121761128
ECAD: 122604998
LSV: 111905740
DCR: 108210643
CSIN: 114318803
BVG: 104904012
SOE: 110794839
NNU: 104594555
MING: 122077021
TSS: 122661910
NCOL: 116255717
OSA: 4324516
DOSA: Os01t0150000-01(Os01g0150000)
OBR: 102717286
BDI: 100830422
ATS: 109777279
TUA: 125542658
SBI: 8060800
ZMA: 100191179
SITA: 101781761
SVS: 117857367
PHAI: 112895985
EGU: 105052214
MUS: 103987000
ATR: 18436069
MNG: MNEG_5026
APRO: F751_1654
SCE: YDL015C(TSC13)
SEUB: DI49_1039
ERC: Ecym_5259
KMX: KLMA_10196(TSC13)
NCS: NCAS_0I01880(NCAS0I01880)
NDI: NDAI_0A06480(NDAI0A06480)
TPF: TPHA_0A04340(TPHA0A04340)
TBL: TBLA_0B01660(TBLA0B01660)
TDL: TDEL_0D04380(TDEL0D04380)
KAF: KAFR_0F02320(KAFR0F02320)
KNG: KNAG_0K01650(KNAG0K01650)
PIC: PICST_39084(TSC13)
CAL: CAALFM_C101050CA(CaO19.3293)
SLB: AWJ20_1731(TSC13)
NCR: NCU03362
NTE: NEUTE1DRAFT117529(NEUTE1DRAFT_117529)
MGR: MGG_03250
SSCK: SPSK_00299
MAW: MAC_05645
MAJ: MAA_01851
CMT: CCM_05177
MBE: MBM_02606
ANI: AN1968.2
ANG: ANI_1_968184(An04g05930)
ALUC: AKAW2_51558S(TSC13)
ACHE: ACHE_10810A(TSC13)
APUU: APUU_21089A(TSC13)
ABE: ARB_02271
TVE: TRV_04982
PNO: SNOG_07392(SNOG_07391)
PTE: PTT_16464
CNE: CNE01780
CNB: CNBE1760
TASA: A1Q1_00775
SCM: SCHCO_02626626(SCHCODRAFT_02626626)
MGL: MGL_0166
MRT: MRET_1151
DDI: DDB_G0270270(gpsn2)
DFA: DFA_02956(gpsn2)
EHI: EHI_045030(3.t00089) EHI_076870(40.t00027)
PCB: PCHAS_071400(PC000427.01.0)
TAN: TA18840
TPV: TP03_0656
BBO: BBOV_III001830(17.m10668)
CPV: cgd2_1200
SPAR: SPRG_07122
TCR: 457251.10
LMA: LMJF_25_1770(EnCR)
LPAN: LPMP_251850(ENCR)
 » show all
Reference
  Authors
Kohlwein SD, Eder S, Oh CS, Martin CE, Gable K, Bacikova D, Dunn T
  Title
Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae.
  Journal
Mol Cell Biol 21:109-25 (2001)
DOI:10.1128/MCB.21.1.109-125.2001
  Sequence
[sce:YDL015C]
Reference
  Authors
Gable K, Garton S, Napier JA, Dunn TM
  Title
Functional characterization of the Arabidopsis thaliana orthologue of Tsc13p, the enoyl reductase of the yeast microsomal fatty acid elongating system.
  Journal
J Exp Bot 55:543-5 (2004)
DOI:10.1093/jxb/erh061
  Sequence
[ath:AT3G55360]
Reference
PMID:12482854 (H.sapiens)
  Authors
Moon YA, Horton JD.
  Title
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade.
  Journal
J Biol Chem 278:7335-43 (2003)
DOI:10.1074/jbc.M211684200
  Sequence
[hsa:9524]

KEGG   ENZYME: 1.3.1.93
Entry
EC 1.3.1.93                 Enzyme                                 
Name
very-long-chain enoyl-CoA reductase;
TSC13 (gene name);
CER10 (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
very-long-chain acyl-CoA:NADP+ oxidoreductase
Reaction(IUBMB)
a very-long-chain acyl-CoA + NADP+ = a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+ [RN:R10828]
Reaction(KEGG)
R10828;
(other) R07761 R09449
Substrate
very-long-chain acyl-CoA [CPD:C20876];
NADP+ [CPD:C00006]
Product
very-long-chain trans-2,3-dehydroacyl-CoA [CPD:C20879];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase.
History
EC 1.3.1.93 created 2012
Pathway
ec00062  Fatty acid elongation
ec01040  Biosynthesis of unsaturated fatty acids
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K10258  very-long-chain enoyl-CoA reductase
Genes
HSA9524(TECR)
PTR455786(TECR)
PPS100971383(TECR)
GGO109025468(TECR)
PON100440904(TECR)
NLE100581652(TECR)
MCC718928(TECR)
MCF101926702(TECR)
CSAB103234044(TECR)
CATY105601591(TECR)
PANU101026540(TECR)
TGE112613496(TECR)
RRO104661039(TECR)
RBB108514773(TECR)
TFN117076184(TECR)
PTEH111546248 111554381(TECR)
CJC100402213(TECR)
SBQ101033875(TECR)
CSYR103261896(TECR)
MMUR105867918(TECR)
LCAT123637858(TECR) 123638708
OGA100961670(TECR)
MMU106529(Tecr)
MCAL110300213(Tecr)
MPAH110337246(Tecr)
RNO191576(Tecr) 499018(RGD1560015)
MCOC116069683(Tecr)
MUN110545857(Tecr)
CGE100761652(Tecr)
MAUA101826283(Tecr)
PLEU114688224(Tecr)
MORG121455891(Tecr)
AAMP119801779(Tecr)
NGI103751841(Tecr)
HGL101716060(Tecr)
CPOC100714067(Tecr)
CCAN109686636(Tecr)
DORD105999261(Tecr)
DSP122119692(Tecr)
NCAR124968574
OPI101534989(TECR)
TUP102480210(TECR)
CFA476687(TECR)
CLUD112666635(TECR)
VVP112908161(TECR)
VLG121494403(TECR)
AML100467030(TECR) 117801863
UMR103682180(TECR)
UAH113247156(TECR)
UAR123801754(TECR)
ELK111162454
LLV125083500
MPUF101676388(TECR)
ORO101386071(TECR)
EJU114197645(TECR)
ZCA113916285(TECR)
MLX118005922(TECR)
FCA101091601(TECR)
PYU121024688(TECR)
PBG122486995(TECR)
PTG102959844(TECR)
PPAD109247758 109253922(TECR)
AJU106986213(TECR)
HHV120245260(TECR)
BTA614105(TECR)
BOM102285957(TECR)
BIU109561491(TECR)
BBUB102397352(TECR)
CHX102187120(TECR)
OAS101117331(TECR)
ODA120864104(TECR)
CCAD122440561(TECR)
SSC100515709(TECR)
CFR102519742(TECR)
CBAI105068292(TECR)
CDK105105973(TECR)
VPC102545694(TECR)
BACU102997227(TECR)
LVE103070891(TECR)
OOR101269817(TECR)
DLE111166579(TECR)
PCAD102975948(TECR)
PSIU116751802(TECR)
ECB100065024(TECR)
EPZ103565661(TECR)
EAI106844303(TECR)
MYB102260613(TECR)
MYD102751823(TECR)
MMYO118652703(TECR)
MLF102420692(TECR)
MNA107542369(TECR)
PKL118706496(TECR)
HAI109394266(TECR)
DRO112301386(TECR)
SHON118984073(TECR)
AJM119049699(TECR)
PDIC114502622(TECR)
PHAS123828267(TECR)
MMF118615910(TECR)
RFQ117037956(TECR)
PALE102887858(TECR)
PGIG120618471(TECR)
PVP105308511(TECR)
RAY107519419(TECR)
MJV108393978(TECR)
TOD119241043(TECR)
SARA101543878 101557823(TECR)
LAV100674918(TECR)
TMU101348735
DNM101439800(TECR)
MDO100026440(TECR) 100032861
GAS123242624(TECR)
SHR100914010(TECR) 116423386
PCW110197969 110203436(TECR)
OAA100080249 100081999(TECR)
GGA107050163 424491(TECR)
PCOC116238972(TECR) 116243504
MGP100545685(TECR)
CJO107317393
NMEL110402349(TECR)
APLA101799511(TECR)
ACYG106039444(TECR)
AFUL116491679(TECR)
TGU100230168
LSR110468229(TECR)
SCAN103815135(TECR)
PMOA120508662 120510871
OTC121339181 121345143
PRUF121362023 121363358
GFR102032504(TECR)
FAB101810425(TECR)
PHI102099600(TECR) 106628096
PMAJ107208393
CCAE111922653(TECR) 111932652
CCW104695353(TECR)
CBRC103612775(TECR)
ETL114055627(TECR)
ZAB102066769(TECR)
FPG101910412
FCH102049843(TECR)
CLV110363827(TECR)
EGZ104134018(TECR)
NNI104015498
PLET104621069(TECR)
PCRI104025245(TECR)
ACUN113482866(TECR)
TALA104358085(TECR)
PADL103925113(TECR)
ACHC115348278 115348983
HALD104324182(TECR)
CCRI104161161(TECR)
CSTI104555420(TECR)
EHS104504550(TECR)
FGA104082968(TECR)
GSTE104261550(TECR)
LDI104344721(TECR)
MNB103781130
AAM106499774(TECR)
AROW112961864(TECR)
NPD112946229(TECR)
DNE112979796(TECR)
ASN102370679(TECR) 102383204
AMJ102559187(TECR) 102575131
CPOO109307274(TECR)
GGN109286852(TECR)
PSS102457301(TECR) 102459125
CMY102929357(TECR) 102931932
CPIC101937001(TECR) 101945886
TST117881252 117888503(TECR)
CABI116820507 116825406(TECR)
MRV120370281 120391408(TECR)
ACS100560578 100566730(tecr)
PVT110070802(TECR) 110076484
SUND121921198(TECR) 121928617
PBI103058993 103065171(TECR)
PMUR107292471(TECR) 107295608
TSR106543114(TECR)
PGUT117659321(TECR) 117677238
VKO123024554 123035425(TECR)
PMUA114590788(TECR) 114598728
ZVI118079968(TECR) 118088377
GJA107112228 107117643(TECR)
STOW125427835 125432572
XLA108713542(MGC146850.L) 380153(tecr.L) 444160(tecr.S)
XTR493561(tecr) 780081(MGC146850)
NPR108789250 108797751(TECR)
RTEM120933242(TECR) 120945671
BBUF120978502 120986215(TECR)
BGAR122927358 122927359 122943401
DRE326954(tecrb) 450002(tecrl2b) 566085(tecra) 798606(tecrl2a)
SRX107711203 107714113 107729653 107745691 107747144(tecr)
SANH107661839 107670448 107680044 107694603 107697782 107703756
SGH107564537 107573605 107594239 107599304 107602715
CCAR109063766 109080996 109103830 109106768
CAUA113042176 113051426 113066137 113067679 113074513 113097128 113115733
PPRM120477422 120482037(tecrl2b) 120487850 120488094 120489016(tecra)
MAMB125251117(tecrl2b) 125255757(tecra) 125258034(tecrl2a) 125278130(tecrb)
IPU100528865(tecrb) 108255190(tecrl2a) 108256782(tecra)
PHYP113524968 113537422(tecr) 113546295 113547559
SMEO124376328(tecra) 124378407(tecrb) 124384339(tecrl2a) 124402984(tecrl2b)
TFD113636364(tecrb) 113649827(tecrl2a) 113655481(tecrl2b) 113661946(tecra)
AMEX103029998 103040826 103043316 103047753(tecr)
EEE113584545 113590736 113592021(tecr)
TRU101061272 101070143(tecr) 101076261
TNGGSTEN00016634G001 GSTEN00026306G001
LCO104918595 104923104
NCC104943218 104960308
CGOB115009472(tecr) 115011694 115025451
ELY117255374(tecrb) 117264704 117268496(tecra)
EFO125879780(tecra) 125882307(tecrl2a) 125885560(tecrb)
PLEP121956431(tecra) 121960674
SLUC116042814(tecrb) 116055761 116059458(tecra)
ECRA117937872 117958745(tecra) 117959246(tecrb)
PFLV114549393 114565710(tecr) 114568924
GAT120811678 120825752(tecrb) 120827143(tecra)
PPUG119198318 119217402(tecrb) 119220462(tecra)
MSAM119896514(tecra) 119899464(tecrb) 119907318
CUD121503681(tecra) 121508514(tecrb) 121527467
ALAT119008691 119013482(tecra) 119025994(tecrb)
MZE101469805 101471785 101483996(tecr)
ONL100699909 100701654(tecr) 100710535
OAU116310621(tecrb) 116317697(tecra) 116335763
OLA101155407(tecr) 101163495 101171706
OML112137470(tecrb) 112146832(tecra) 112151473
XMA102220976 102224233 102224945(tecr)
XCO114136676 114144650(tecr) 114159783
XHE116711637 116720152(tecr) 116735325
PRET103461133(tecr) 103482281
PFOR103143338 103143372 103151989 103154161(tecr)
PLAI106945992(tecr) 106958234 106963585
PMEI106914552 106922055(tecr) 106932487
GAF122821457(tecra) 122824237(tecrl2a) 122829703(tecrb)
CVG107084911 107093427 107094408(tecr)
CTUL119794849(tecra) 119795985 119798025(tecrb)
GMU124857930(tecrl2a) 124862898 124864986 124868154(tecrb)
NFU107378295 107390378
KMR108241336(tecra) 108241483(tecrb)
ALIM106529633 106530387(tecr)
NWH119421720(tecra) 119422775(tecrb)
AOCE111569904(tecr) 111573670 111574563
MCEP124995889(tecrl2a) 124998441(tecra) 125003991(tecrb)
CSEM103377076 103383916(tecr) 103392722
POV109627729(tecr) 109629827 109634303
SSEN122771204(tecrb) 122772526(tecrl2a) 122785720(tecra)
HHIP117753845 117765698(tecra) 117769039(tecrb)
HSP118098778(tecrl2a) 118120502(tecrb) 118123350(tecra)
LCF108885426(tecr) 108902677
SDU111227218 111228193 111229346(tecr)
SLAL111648242 111653695 111665569(tecr)
XGL120788205(tecra) 120789966 120800507(tecrb)
HCQ109521419 109527436(tecr)
BPEC110165444 110166151 110169504
MALB109952401(tecr) 109966006
BSPL114851837(tecrb) 114854026 114861094(tecra)
SASA106564267(tecr) 106569794 106590656
OTW112215531 112260940 121841110
OMY110485397(tecrb) 110486719 110489543 110530851 110535481 110538672
OGO123990210(tecrl2a) 123998942 124003155(tecrb) 124009868 124015393 124019190 124039094
ONE115104342 115114041 115120682 115123622
SALP111972518 112071494 112073603
SNH120027677 120034433 120040317(tecrb) 120041688 120044634 120050274
CCLU121534507 121550100 121551302(tecra) 121553943(tecrb) 121568868 121570633
ELS105010434 105013088 105022597 105029730(tecr)
SFM108919751 108935248
PKI111840958 111849227 111849411
AANG118219786(tecrb) 118225720
LOC102686016 102686340(tecr)
PSPA121304508(tecrb) 121326563 121330590
ARUT117402162(tecrb) 117408311 117417360 117962766
LCM102356009 102357997
CMK103174648 103191170
RTP109916854(tecr)
BFO118431796
BBEL109486152
CIN100183960
SCLV120339053
SPU100891906 576023
APLC110985205
SKO100372208
DMEDmel_CG10849(Sc2)
DER6546239
DSE6610677
DSIDsimw501_GD13786(Dsim_GD13786)
DYADyak_GE21388
DAN6506865
DSR110183653
DPO4812074
DPE6601109
DMN108152677
DWI6643043
DGR6558720
DMODmoj_GI12546
DAZ108613041
DNV108652307
DHE111596861
DVI6636822
CCAT101451986
BOD106625933
MDE101887858
SCAC106088957
LCQ111684843
LSQ119614956
HIS119655714
AGAAgaP_AGAP010714
ACOZ120955082
AARA120903293
ASTE118505333
AAG5570994
AALB109418540 115257884
CQUCpipJ_CPIJ005584
CPII120414909
CNS116351695
BCOO119072652
AME725146
ACER107996601
ALAB122714998
BIM100747299
BBIF117205321
BVK117238802
BVAN117157507
BTER100644169
BPYO122567664
CCAL108626760
OBB114875737
MGEN117218808
NMEA116427316
CGIG122399107
SOC105193039
MPHA105834618
AEC105153980
ACEP105618040
PBAR105433004
VEM105563404
HST105181228
DQU106746495
CFO105259215
FEX115242265
LHU105673344
PGC109859407
OBO105282481
PCF106791875
PFUC122522405
VPS122636487
NVI107980451
CSOL105366015
TPRE106647989
MDL103579818
CGLO123267621
FAS105268286
DAM107045802
AGIF122851250
CCIN107269001
TCA659815
DPA109537890
SOY115876726
ATD109608357
CSET123321790
AGB108907369
NVL108567063
APLN108740928
PPYR116166007
OTU111421540
BMOR101742899
MSEX115455791
DPLKGM_203700
BANY112049612
PMAC106718707
PPOT106100594
PXU106124851
PRAP110995799
ZCE119829437
HAW110375119
HZE124633678
TNL113496889
SLIU111353415
OFU114349809
PXY105385206
AGS114122650
RMD113560909
BTAB109042406 109044523
DCI103515585
CLEC106664306
HHAL106687828
NLU111045413 120349590
PHUPhum_PHUM037790
FOC113210083
TPAL117642585
ZNE110835131
CSEC111863541
FCD110859769
DPXDAPPUDRAFT_199063
DMK116917298
PVM113827755
PJA122251137
PCHN125025654
HAME121875625
PCLA123765086
PTRU123518808
HAZT108671836
EAF111708945 111718244 111718258
LSM121119024
PPOI119098659
ISCIscW_ISCW002618
DSV119432651 119433389
RSAN119405195
RMP119181189
VDE111245145
VJA111269559
TUT107369209
DPTE113796694 113799520
DFR124495727
CSCU111629930
PTEP107441461
SDM118182071
CELCELE_C15F1.6(art-1)
CBRCBG_11196(Cbr-art-1)
NAINECAME_05127
TSPTsp_07269
HROHELRODRAFT_155722
LGILOTGIDRAFT_232335
PCAN112573754
BGT106077618
GAE121374304
HRF124135578
HRJ124260109
CRG105326706
MYI110461543
PMAX117326220
MMER123524742
OBI106878132
OSN115218830 115219109
LAK106164649
SMMSmp_081820.1
OVIT265_14517
EGLEGR_03533
NVE5512326
EPA110241894
ATEN116291763
ADF107357184
AMIL114956483
PDAM113679514
SPIS111341682
DGT114526317
XEN124442083
HMG100209541
TADTRIADDRAFT_29423
AQU100640363
ATHAT3G55360(CER10)
ALY9312365
CRB17884738
CSAT104781415 104791824
EUSEUTSA_v10010564mg
BRP103841442
BNA106396280 106415464
BOE106312603
RSZ108805403
THJ104810019
CIT102619239
CICCICLE_v10032183mg
PVY116117715
MINC123192664 123228367
TCC18586099
GRA105776424 105780559
GHI107904734 107934412 107959873 121207779
GAB108458231 108464425
DZI111296266 111310214
EGR104454293
GMX100780327 100785393
GSJ114385421 114400569
PVUPHAVU_008G208700g
VRA106762967
VAR108337072
VUN114195412
CCAJ109795557
APRC113846884
MTRMTR_5g087590
CAM101508101(sr5a)
ADU107496735
AIP107609317
AHF112702185 112766158
LANG109356796
FVE101313554
RCN112182703
PPER18784679
PMUM103332647
PAVI110756623
PDUL117617726
MDM103406406 103445586
PXB103935366
ZJU107413483
MNT21394038
CSV101213758
CMO103498153
BHJ120069885 120079933
MCHA111006458 111013716
CMAX111487465 111489004
CMOS111429991 111444958
CPEP111808372
RCU8267764
JCU105647736
HBR110649118
MESC110619378 110624009
POP7458148 7467545
PEU105127546 105128804
PALZ118052410 118059725
JRE108979647 108986368
QSU111987111 112014784 112027661
QLO115957498
TWL119990040 120004911
VVI100266766
VRI117929129
SLY101263911
SPEN107020319
SOT102581846
SSTN125867929
CANN107870238
NTA107785715 107796650(ER)
NSY104222744
NTO104088381
NAU109240729
INI109186449
ITR116014001
SIND105171911
OEU111397371 111406020
EGT105962734
SSPL121761128
HAN110872584 110904732 110913412
ECAD122604998
LSV111905740
CCAV112520649 112525420
DCR108210643
CSIN114318803
BVG104904012
SOE110794839
CQI110715278 110724891
NNU104594555
MING122077021
TSS122661910
PSOM113313744 113322500 113345081
NCOL116255717
OSA4324516
DOSAOs01t0150000-01(Os01g0150000)
OBR102717286
BDI100830422
ATS109777279
TDC119266977 119274774
TAES123060149 123068633 123077157
TUA125542658
SBI8060800
ZMA100191179
SITA101781761
SVS117857367
PVIR120672887 120705981
PHAI112895985
PDA103696797 103703465
EGU105052214
MUS103987000
DCT110111342 110115851
PEQ110022982 110024888 110024890
AOF109820289 109829876
ATR18436069
SMOSELMODRAFT_186154 SELMODRAFT_270920
PPP112293200 112293489
CRECHLRE_14g615050v5
VCNVOLCADRAFT_72272
MNGMNEG_5026
CSLCOCSUDRAFT_36177
CVRCHLNCDRAFT_20573
APROF751_1654
OLUOSTLU_49170
OTAOT_ostta03g04210
BPGBathy07g01910
MISMICPUN_60190
MPPMICPUCDRAFT_49391
CMECYME_CMD146C
CCPCHC_T00008438001
SCEYDL015C(TSC13)
SEUBDI49_1039
SPAOSPAR_D02100
AGOAGOS_AER215W
ERCEcym_5259
KLAKLLA0_C04367g
KMXKLMA_10196(TSC13)
LTHKLTH0E15950g
VPOKpol_1010p67
ZROZYRO0A05038g
CGRCAGL0K01837g
NCSNCAS_0I01880(NCAS0I01880)
NDINDAI_0A06480(NDAI0A06480)
TPFTPHA_0A04340(TPHA0A04340)
TBLTBLA_0B01660(TBLA0B01660)
TDLTDEL_0D04380(TDEL0D04380)
TGBHG536_0G02880
KAFKAFR_0F02320(KAFR0F02320)
KNGKNAG_0K01650(KNAG0K01650)
ZMKHG535_0C02530
PPAPAS_chr4_0780
DHADEHA2B00968g
PICPICST_39084(TSC13)
PGUPGUG_00050
SPAASPAPADRAFT_132798
LELLELG_01381 LELG_05600
CALCAALFM_C101050CA(CaO19.3293)
CTPCTRG_04406
COTCORT_0B11210
CDUCD36_00990
CTENCANTEDRAFT_108493
YLIYALI0A04983g
CLUCLUG_00022
CLUSA9F13_19g00858
CAURCJI97_003042
SLBAWJ20_1731(TSC13)
PKZC5L36_0B10020
BNNFOA43_002705
BBRXBRETT_001603
OPAHPODL_01397
SLUDSCDLUD_002395
NCRNCU03362
NTENEUTE1DRAFT117529(NEUTE1DRAFT_117529)
SMPSMAC_04071
PANPODANSg6420
TTTTHITE_2123364
MTMMYCTH_2145474
CTHRCTHT_0001860
MGRMGG_03250
PPEIPpBr36_06385
TMNUCRPA7_5124
SSCKSPSK_00299
FGRFGSG_00629
FPUFPSE_06407
FVRFVEG_00568
FOXFOXG_00946
NHENECHADRAFT_98899
TRETRIREDRAFT_105035
TRRM419DRAFT_71215
MAWMAC_05645
MAJMAA_01851
CMTCCM_05177
PLJVFPFJ_07112
VALVDBG_05577
VDAVDAG_07519
CFJCFIO01_07269
CHIGCH63R_10413
SAPOSAPIO_CDS0152
ELAUCREL1_8704
PFYPFICI_08759
SSLSS1G_10706
BFUBCIN_04g05010
MBEMBM_02606
PSCOLY89DRAFT_737543
GLZGLAREA_03598
ANIAN1968.2
AFMAFUA_4G10760
ACTACLA_049930
NFINFIA_105330
AORAO090003001139 AO090038000096
ANGANI_1_968184(An04g05930)
AFVAFLA_000527 AFLA_012367
ALUCAKAW2_51558S(TSC13)
ACHEACHE_10810A(TSC13)
APUUAPUU_21089A(TSC13)
PCSPc22g07000
PDPPDIP_33130
TMFPMAA_040700
TRGTRUGW13939_02772
CIMCIMG_01478
CPWCPC735_049630
UREUREG_05117
PBLPAAG_02630
PBNPADG_01649
ABEARB_02271
TVETRV_04982
BGHBDBG_03510
PNOSNOG_07392(SNOG_07391)
PTEPTT_16464
BZECOCCADRAFT_34894
BSCCOCSADRAFT_104969
BORCOCMIDRAFT_101215
AALTCC77DRAFT_979969
ZTRMYCGRDRAFT_98769
PFJMYCFIDRAFT_76038
FFUCLAFUR5_02219
BCOMBAUCODRAFT_34915
NPAUCRNP2_7555
TMLGSTUM_00001911001
SPOSPBC646.07c
CNECNE01780
CNBCNBE1760
CNGCNAG_02372
CGICGB_E2340W
TMSTREMEDRAFT_71207
TASAA1Q1_00775
TVSTRAVEDRAFT_126270
DSQDICSQDRAFT_166875
PCOPHACADRAFT_89473
SHSSTEHIDRAFT_141777
HIRHETIRDRAFT_54691
PSQPUNSTDRAFT_116689
ADLAURDEDRAFT_105341 AURDEDRAFT_152816
FMEFOMMEDRAFT_102627
GTRGLOTRDRAFT_78098
LBCLACBIDRAFT_251245
MRRMoror_17838
MOREE1B28_010233
CCICC1G_10032
SCMSCHCO_02626626(SCHCODRAFT_02626626)
PCUBJR316_0006352
CPUTCONPUDRAFT_99121
SLASERLADRAFT_449601
WSEWALSEDRAFT_66778
WICJ056_002528
UMAUMAG_03622
PFPPFL1_02440
MGLMGL_0166
MRTMRET_1151
MSYMMSY001_0546
PGRPGTG_02971
MLRMELLADRAFT_87292
DDIDDB_G0270270(gpsn2)
DPPDICPUDRAFT_52983
DFADFA_02956(gpsn2)
EHIEHI_045030(3.t00089) EHI_076870(40.t00027)
EDIEDI_220060 EDI_292090
EIVEIN_097750
ACANACA1_079010
PFAPF3D7_1135900
PREIPRSY57_1134300
PGABPGSY75_1135900
PYOPY17X_0914200
PCBPCHAS_071400(PC000427.01.0)
PBEPBANKA_0912700
PVVPVVCY_0903440
PKNPKNH_0934100
PVXPVX_092410
TANTA18840
TPVTP03_0656
TOTTOT_030000211
BEQBEWA_053220
BBOBBOV_III001830(17.m10668)
BMICBmR1_04g05395
BBIGBBBOND_0303300
CPVcgd2_1200
CHOChro.20132
TETTTHERM_00401940
PTMGSPATT00012181001 GSPATT00013728001
PIFPITG_04333
PSOJPHYSODRAFT_285961
SPARSPRG_07122
TBRTb927.3.1840
TBGTbgDal_III1700
TCR457251.10
LMALMJF_25_1770(EnCR)
LIFLINJ_25_1850
LDOLDBPK_251850
LMILMXM_25_1770
LPANLPMP_251850(ENCR)
NGRNAEGRDRAFT_83127
TVATVAG_231320
GLAGL50803_0088581
 » show all
Reference
1  [PMID:11113186]
  Authors
Kohlwein SD, Eder S, Oh CS, Martin CE, Gable K, Bacikova D, Dunn T
  Title
Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae.
  Journal
Mol Cell Biol 21:109-25 (2001)
DOI:10.1128/MCB.21.1.109-125.2001
  Sequence
[sce:YDL015C]
Reference
2  [PMID:14673020]
  Authors
Gable K, Garton S, Napier JA, Dunn TM
  Title
Functional characterization of the Arabidopsis thaliana orthologue of Tsc13p, the enoyl reductase of the yeast microsomal fatty acid elongating system.
  Journal
J Exp Bot 55:543-5 (2004)
DOI:10.1093/jxb/erh061
  Sequence
[ath:AT3G55360]
Reference
3  [PMID:15958487]
  Authors
Kvam E, Gable K, Dunn TM, Goldfarb DS
  Title
Targeting of Tsc13p to nucleus-vacuole junctions: a role for very-long-chain fatty acids in the biogenesis of microautophagic vesicles.
  Journal
Mol Biol Cell 16:3987-98 (2005)
DOI:10.1091/mbc.e05-04-0290
  Sequence
[sce:YDL015C]
Reference
4  [PMID:15829606]
  Authors
Zheng H, Rowland O, Kunst L
  Title
Disruptions of the Arabidopsis Enoyl-CoA reductase gene reveal an essential role  for very-long-chain fatty acid synthesis in cell expansion during plant morphogenesis.
  Journal
Plant Cell 17:1467-81 (2005)
DOI:10.1105/tpc.104.030155
  Sequence
[ath:AT3G55360]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.93
IUBMB Enzyme Nomenclature: 1.3.1.93
ExPASy - ENZYME nomenclature database: 1.3.1.93
BRENDA, the Enzyme Database: 1.3.1.93

KEGG   REACTION: R07761
Entry
R07761                      Reaction                               
Name
octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
Definition
(2E)-Octadecenoyl-CoA + NADPH + H+ <=> Stearoyl-CoA + NADP+
Equation
Reaction class
RC00001  C00005_C00006
RC00052  C00412_C16218
Enzyme
Pathway
rn01040  Biosynthesis of unsaturated fatty acids
rn01212  Fatty acid metabolism
Orthology
K10258  very-long-chain enoyl-CoA reductase [EC:1.3.1.93]

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