KEGG   ORTHOLOGY: K11251
Entry
K11251                      KO                                     

Symbol
H2A
Name
histone H2A
Pathway
map04217  Necroptosis
map04613  Neutrophil extracellular trap formation
map05034  Alcoholism
map05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11251  H2A; histone H2A
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K11251  H2A; histone H2A
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K11251  H2A; histone H2A
  09165 Substance dependence
   05034 Alcoholism
    K11251  H2A; histone H2A
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K11251  H2A; histone H2A
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K11251  H2A; histone H2A
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Nucleosome assembly factors
   Histones
    K11251  H2A; histone H2A
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K11251  H2A; histone H2A
Genes
HSA: 221613(H2AC1) 3012(H2AC8) 3013(H2AC7) 3014(H2AX) 3015(H2AZ1) 317772(H2AC21) 474381(H2AB2) 474382(H2AB1) 55506(MACROH2A2) 55766(H2AJ) 723790(H2AC19) 8329(H2AC13) 8330(H2AC15) 8331(H2AC14) 8332(H2AC16) 8334(H2AC6) 8335(H2AC4) 8336(H2AC17) 8337(H2AC18) 8338(H2AC20) 83740(H2AB3) 85235(H2AC12) 8969(H2AC11) 92815(H2AW) 94239(H2AZ2) 9555(MACROH2A1)
PTR: 104001345(H2AFX) 107970947 107971249 107971253 107971372 112206877 450509(H2AFY2) 453664(H2AFV) 457261(HIST2H2AC) 461400(H2AFZ) 462076(H2AFY) 462486(HIST1H2AA) 462490 462493 462506 465306(H2AFJ) 469700(HIST3H2A) 471884(HIST1H2AE) 471887 471894 471895 471905 471909 736529 737087 746468 746557(HIST2H2AB) 748495
PPS: 100974647 100974651 100974682 100974858 100974973 100975117 100976242 100978953 100979157 100980195 100982169 100982497 100984913 100985121 100985779 100986643 100988670 100989678 100990022 100990167 100992550 100992822 100994157 103783475 103785886 103786978 106635181
GGO: 101123911 101125738 101126098 101127003 101127738 101129166 101129330 101131222 101131632 101131885 101133280 101133882 101134814 101135339 101136257 101138472 101140733 101141483 101141751 101142869 101144335 101144401 101151967 101152776 101154087 109023047 109024628 115932133 115932200
PON: 100174379(H2AFZ) 100431754 100433891 100434269 100435022 100435391 100438976 100439088 100439702 100439884 100442522 100446506 100448122 100449561 100454188 100456246 100456998 100457330 100462394 100462573 103890842 103891543 112130766 112130778 112130917 112133911
NLE: 100582700 100585611 100585797 100586992 100587000 100588416 100589309 100591739 100593126 100593228 100593802 100593890 100594276 100595010 100595043 100595527 100595614 100595867 100596044 100598019 115832937 115833249 115837632 115837634
MCC: 106995531 114670854 114675038 114677660 693768(HIST3H2A) 695551(HIST1H2AE) 696463 696629(HIST1H2AC) 697235(HIST1H2AD) 697977 698239(HIST1H2AA) 701574 701826 701863(H2AFJ) 701962 703044(H2AFB3) 703073(H2AFX) 704006(HIST1H2AK) 704127(HIST1H2AJ) 704664 704994 705054(HIST2H2AC) 705170(HIST2H2AB) 705469 705636 709326(H2AFZ) 711117(H2AFY2) 711836(H2AFY)
MCF: 102117823 102117971 102118091 102118097 102118844 102119981 102120368 102123677 102124317 102125104 102127391 102130495 102132314 102132379 102137182 102137365 102137997 102141626 102144583 102144964 107126377 107129593 107129603
CSAB: 103216062(H2AFY2) 103218675(H2AFJ) 103221935(HIST1H2AM) 103221936 103221939 103221943(HIST1H2AL) 103221947 103221968 103221970 103221997 103222003 103222014 103222032 103226127(H2AFV) 103229950(HIST3H2A) 103232850 103232851 103236032 103236164 103244568(H2AFY) 103247168(HIST2H2AC) 103247169(HIST2H2AB) 103247785 103248619(H2AFX)
CATY: 105572092 105572636 105572649 105572659 105572669 105572674 105573760 105582501 105585119 105590173 105590174 105592902 105593168 105593171 105593175 105593178 105593180 105593193 105593196 105596899 105597270 105597695 105599793
MMU: 100039319(H2ab1) 100042840(H2al2b) 100042922(H2al1a) 100042927(H2al1b) 100042929(H2al1c) 100042931(H2al1d) 100042939(H2al1f) 100042943(H2al1g) 100042944(H2al1h) 100042946(H2al1i) 15267(H2ac18) 15270(H2ax) 232440(H2aj) 236663(H2al1j) 26914(Macroh2a1) 319162(H2aw) 319163(H2ac1) 319164(H2ac6) 319165(H2ac7) 319166(H2ac8) 319167(H2ac11) 319168(H2ac12) 319169(H2ac15) 319170(H2ac22) 319171(H2ac24) 319172(H2ac4) 319173(H2ac10) 319176(H2ac20) 319191(H2ac13) 319192(H2ac19) 333452(H2al1o) 385317(H2al3) 385328(H2al1n) 404634(Macroh2a2) 51788(H2az1) 547154(H2al1k) 547160(H2al1e) 547210(H2al2c) 621893(H2ac21) 624153(H2ab2) 624957(H2ab3) 665433(H2ac23) 68231(H2al2a) 76383(H2al1m) 77605(H2az2)
RNO: 100360754(Hist1h2ai) 100363171 100910554 103690190 24828(H2ac1) 29384(Macroh2a1) 302783(H2ab3) 306962(Hist1h2ac) 306970(Hist1h2an) 361844(Macroh2a2) 365877(Hist2h2aa3) 498753(Hist1h2af) 498894(RGD1560813) 499675(H2ac20) 500987(H2ax) 502125(Hist1h2ah) 502129(hist1h2ail2) 58940(H2az1) 64646(Hist3h2a) 680322(H2ac12) 680615(Hist1h2ak) 684773 685069 685909(H2az2) 689408 690102(H2ac21) 690131(Hist2h2aa2) 690795(H2aj)
CFA: 100855593(H2AC20) 100855609(H2AC21) 100856200(H2AC8) 102157138 106558234(H2AC15) 106558405 111093989(H2AC4) 111094037(H2AC9) 119863943 475501(H2AZ2) 478493(H2AZ1) 481514(MACROH2A1) 482203(H2AW) 483168(H2AC19) 486669(H2AJ) 488251(H2AC1) 488254(H2AC2) 488262(H2AC5) 488268(H2AC6) 488289(H2AC11) 488291(H2AC12) 488297(H2AC13) 488304(H2AC16) 488308(H2AC17) 489024(MACROH2A2) 489372(H2AX) 491818 491827 611231(H2AC14) 612656(H2AB3)
BTA: 100297758(HIST2H2AA4) 104968446 104975683 104975684 112445453 112445454 112445455 112445460 112445461 287016(H2AFZ) 506900(HIST1H2AC) 513666(HIST2H2AC) 523631 524176 524236 524808(HIST1H2AC) 528006 529277 531733(H2AFX) 532990(H2AFY) 537167(H2AFY2) 538911(HIST3H2A) 541108(HIST1H2AK) 613618(H2AFV) 614881 614970 614974(HIST2H2AB) 616634(HIST1H2AH) 616790(HIST1H2AG) 617633 618489(H2AFJ) 618824(HIST1H2AM) 783767(HIST1H2AJ) 787441(HIST1H2AA) 788724
GGA: 100857391(H2AFX) 100858459(HIST1H2A4L1) 100859381(H2AFB2) 101749238(HISTH2A4L1) 101751709(H2A2BL) 395858(H2AFY) 404299(HIST1H2A4) 417947(H2AFJ) 417955(HIST1H2A4L3) 423721(H2AFY2) 426361(H2AFZ) 426617(H2AFV) 427881(HIST1H2A3) 427891(HIST1H2A4L2) 427895(HIST1H2A4L4)
XLA: 100036858(macroh2a1.L) 108695576 108696445(h2ax.L) 108696446(h2ax.2.L) 108703786 108703787 108703788 108703789 108703790 108703791 108703792 108704299 108704300 108705228(h2ax.2.S) 108705670 108709196 108715878(h2aj.S) 108716542 108716543 108716544 108717643 108717644 379215(h2az1.L) 379596(h2ac17.L) 380575(macroh2a2.L) 397949(h2az1.S) 432260(h2aj.L) 444168(macroh2a2.S) 444519(h2ac1.S) 444528(h2ax.S) 444541(h2az2.S) 446610(h2ac7.L) 447174 494591(h2ac14.L) 734746(h2ax.lS)
DRE: 100000574(si:ch73-368j24.13) 100000783(si:ch73-368j24.14) 100001004(h2ax2) 100003969(hist1h2a6) 100004011(hist1h2a11) 100004510(si:dkey-23a13.20) 100004768(si:dkey-261m9.7) 100006331(hist1h2a7) 100125271(hist1h2a3) 100148591 100151041(si:ch1073-159d7.11) 100332229(h2af1al) 100332885(hist1h2a10) 100333615(si:dkey-108k21.19) 100334621(si:ch73-36p18.5) 100334934 100536331(si:ch211-113a14.11) 100538134(si:dkey-261m9.18) 101882533(si:ch211-113a14.7) 103908687(si:dkey-23a13.6) 103909881(si:dkey-108k21.15) 103911342(si:ch1073-153i20.5) 103911344(si:ch1073-159d7.9) 252913(h2az2a) 394048(h2ax) 403077(h2az2b) 449794(h2ax1) 554094(hist1h2a2) 558711(macroh2a2) 559220(si:dkey-261m9.15) 560309(si:ch211-113a14.16) 560527(si:ch211-113a14.19) 561187(si:ch211-113a14.26) 563177(si:dkey-261m9.11) 565202(si:ch1073-159d7.10) 570115 606720(hist1h2a4) 678613(macroh2a1)
SASA: 106562913(H2AV) 106567640(H2A) 106569296(H2AV) 106570811(H2AV) 106575627(H2A4) 106575642 106576681(H2AW) 106577590(H2AZ) 106584895(H2AV) 106602874(H2AX) 106603967 106606477(H2AW) 106608632(H2AZ)
DME: Dmel_CG31618(His2A:CG31618) Dmel_CG33808(His2A:CG33808) Dmel_CG33814(His2A:CG33814) Dmel_CG33817(His2A:CG33817) Dmel_CG33820(His2A:CG33820) Dmel_CG33823(His2A:CG33823) Dmel_CG33826(His2A:CG33826) Dmel_CG33829(His2A:CG33829) Dmel_CG33832(His2A:CG33832) Dmel_CG33835(His2A:CG33835) Dmel_CG33838(His2A:CG33838) Dmel_CG33841(His2A:CG33841) Dmel_CG33844(His2A:CG33844) Dmel_CG33847(His2A:CG33847) Dmel_CG33850(His2A:CG33850) Dmel_CG33853(His2A:CG33853) Dmel_CG33856(His2A:CG33856) Dmel_CG33859(His2A:CG33859) Dmel_CG33862(His2A:CG33862) Dmel_CG33865(His2A:CG33865) Dmel_CG5499(His2Av)
DSE: 6617092
DSI: Dsimw501_GD21310(Dsim_GD21310) Dsimw501_GD24322(Dsim_GD24322) Dsimw501_GD24469(Dsim_GD24469) Dsimw501_GD28246(Dsim_GD28246) Dsimw501_GD29224(Dsim_GD29224) Dsimw501_GD29305(Dsim_GD29305)
DAZ: 108620741
CCAT: 101463339
BMOR: 100301498(H2a-l2) 100301499(H2ax-l) 101738772 692353 733117(his2Av)
CEL: CELE_B0035.7(his-47) CELE_C50F4.13(his-35) CELE_F07B7.10(his-51) CELE_F07B7.3(his-53) CELE_F08G2.2(his-43) CELE_F17E9.13(his-33) CELE_F35H10.1(his-30) CELE_F45F2.4(his-7) CELE_F54E12.5(his-57) CELE_F55G1.10(his-61) CELE_H02I12.7(his-65) CELE_K06C4.11(his-19) CELE_K06C4.3(his-21) CELE_R08C7.3(htz-1) CELE_T10C6.12(his-3) CELE_T23D8.6(his-68) CELE_ZK1251.1(htas-1) CELE_ZK131.10(his-16) CELE_ZK131.6(his-12)
BMY: BM_BM2877(Bm2877) BM_BM5298(Bma-htz-1) BM_BM7650(Bm7650)
ATH: AT1G08880(H2AXA) AT1G51060(HTA10) AT1G52740(HTA9) AT1G54690(GAMMA-H2AX) AT2G38810(HTA8) AT3G20670(HTA13) AT3G54560(HTA11) AT4G13570(HTA4) AT4G27230(HTA2) AT5G02560(HTA12) AT5G27670(HTA7) AT5G54640(RAT5) AT5G59870(HTA6)
LJA: Lj0g3v0110789.1(Lj0g3v0110789.1) Lj0g3v0192519.1(Lj0g3v0192519.1) Lj1g3v1914950.1(Lj1g3v1914950.1) Lj1g3v4449230.2(Lj1g3v4449230.2) Lj1g3v4515900.1(Lj1g3v4515900.1) Lj1g3v4921050.1(Lj1g3v4921050.1) Lj1g3v4955240.1(Lj1g3v4955240.1) Lj3g3v1617180.1(Lj3g3v1617180.1) Lj4g3v1812480.1(Lj4g3v1812480.1) Lj5g3v0539920.1(Lj5g3v0539920.1) Lj5g3v1014930.1(Lj5g3v1014930.1)
DOSA: Os01t0502700-00(Os01g0502700) Os03t0162200-01(Os03g0162200) Os03t0279200-01(Os03g0279200) Os03t0721900-00(Os03g0721900) Os03t0743400-01(Os03g0743400) Os04t0212700-00(Os04g0212700) Os05t0113900-01(Os05g0113900) Os05t0461400-02(Os05g0461400) Os06t0250300-00(Os06g0250300) Os07t0545300-01(Os07g0545300) Os07t0545400-01(Os07g0545400) Os08t0289266-00(Os08g0289266) Os08t0427700-00(Os08g0427700) Os10t0418000-01(Os10g0418000) Os12t0438000-02(Os12g0438000) Os12t0530000-01(Os12g0530000)
OLU: OSTLU_119619(H2A) OSTLU_12803(HTA3502) OSTLU_13104(HTA3503) OSTLU_13304(HTA3504)
SCE: YBL003C(HTA2) YDR225W(HTA1) YOL012C(HTZ1)
KMX: KLMA_10259(HTZ1) KLMA_20168(HTA1) KLMA_60119(HTA1)
NCS: NCAS_0A10130(NCAS0A10130) NCAS_0B02750(NCAS0B02750) NCAS_0D02020(NCAS0D02020)
NDI: NDAI_0A07340(NDAI0A07340) NDAI_0C02760(NDAI0C02760) NDAI_0C04940(NDAI0C04940)
TPF: TPHA_0C02050(TPHA0C02050) TPHA_0F02470(TPHA0F02470) TPHA_0L01110(TPHA0L01110)
TBL: TBLA_0E03170(TBLA0E03170) TBLA_0F00320(TBLA0F00320) TBLA_0I02610(TBLA0I02610)
TDL: TDEL_0B01970(TDEL0B01970) TDEL_0D04140(TDEL0D04140) TDEL_0G04260(TDEL0G04260)
KAF: KAFR_0A05230(KAFR0A05230) KAFR_0C00780(KAFR0C00780) KAFR_0F02490(KAFR0F02490)
SLB: AWJ20_1585(HTZ1) AWJ20_910(HTA2)
BNN: FOA43_001789(HTA2_1) FOA43_003746(HTZ1) FOA43_004303(HTA2_2)
BBRX: BRETT_000449(HTZ1) BRETT_002100(HTA2_1) BRETT_004716(HTA2_2)
NCR: NCU02437(hH2A) NCU05347(hH2Az)
NTE: NEUTE1DRAFT84413(NEUTE1DRAFT_84413) NEUTE1DRAFT95713(NEUTE1DRAFT_95713)
SMP: SMAC_04116(putative hta1) SMAC_08324(putative hta2)
MGR: MGG_03577
NHE: NECHADRAFT_59698(HTA2101) NECHADRAFT_98513(HTA2102)
ANG: ANI_1_1484094(An11g11300) ANI_1_252144(An16g01810)
ZTR: MYCGRDRAFT_106181(HTA2402) MYCGRDRAFT_46643(HTA2401)
SPO: SPAC19G12.06c(hta2) SPBC11B10.10c(pht1) SPCC622.08c(hta1)
LBC: LACBIDRAFT_185105(HTA16201) LACBIDRAFT_190022(HTA16202) LACBIDRAFT_190640(HTA16203) LACBIDRAFT_192658(HTA16205) LACBIDRAFT_296217(HTA16204) LACBIDRAFT_380693(HTA16206)
ABP: AGABI1DRAFT115323(AGABI1DRAFT_115323) AGABI1DRAFT115683(AGABI1DRAFT_115683) AGABI1DRAFT86632(AGABI1DRAFT_86632)
ABV: AGABI2DRAFT137793(AGABI2DRAFT_137793) AGABI2DRAFT194286(AGABI2DRAFT_194286) AGABI2DRAFT195036(AGABI2DRAFT_195036)
DDI: DDB_G0279667(H2AX) DDB_G0286747(H2AZ) DDB_G0289187(H2Av1) DDB_G0289197(H2Av3)
DFA: DFA_00261(H2AZ) DFA_07149 DFA_12164(H2AX)
EHI: EHI_126210(117.t00021) EHI_188960(67.t00014)
PCB: PCHAS_111650(PC000638.00.0) PCHAS_121830(PC000384.04.0)
BBO: BBOV_II001900(18.m06146) BBOV_II006460(18.m06532)
SMIN: v1.2.004801.t1(symbB.v1.2.004801.t1)
 » show all
Reference
  Authors
Farris SD, Rubio ED, Moon JJ, Gombert WM, Nelson BH, Krumm A
  Title
Transcription-induced chromatin remodeling at the c-myc gene involves the local exchange of histone H2A.Z.
  Journal
J Biol Chem 280:25298-303 (2005)
DOI:10.1074/jbc.M501784200
  Sequence
[hsa:3015]
Reference
  Authors
Tolstorukov MY, Goldman JA, Gilbert C, Ogryzko V, Kingston RE, Park PJ
  Title
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells.
  Journal
Mol Cell 47:596-607 (2012)
DOI:10.1016/j.molcel.2012.06.011
  Sequence
Reference
  Authors
Hagiwara T, Hidaka Y, Yamada M
  Title
Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes.
  Journal
Biochemistry 44:5827-34 (2005)
DOI:10.1021/bi047505c
  Sequence
[hsa:221613]

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