KEGG ORTHOLOGY: K11539

ORTHOLOGY: K11539

Entry

K11539                      KO

Symbol

CBR4

Name

carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit [EC:1.1.1.-]

Pathway

map00061

Fatty acid biosynthesis

map01100

Metabolic pathways

map01212

Fatty acid metabolism

Module

M00873

Fatty acid biosynthesis in mitochondria, animals

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K11539  CBR4; carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-
     K11539  CBR4; carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit

Other DBs

RN:	R02767 R04533 R04534 R04536 R04543 R04566 R04953 R04964

Genes

HSA:	84869(CBR4)

PTR:	471344(CBR4)

PPS:	100988490(CBR4)

GGO:	101141113(CBR4)

PON:	100462086(CBR4)

NLE:	100579544(CBR4)

HMH:	116466007(CBR4)

MCC:	693949(CBR4)

MCF:	102142233(CBR4)

MTHB:

126955304

MNI:	105466708(CBR4)

CSAB:

103236512(CBR4)

CATY:

105597830(CBR4)

PANU:

101020557(CBR4)

TGE:	112624230(CBR4)

MLEU:

105530308(CBR4)

RRO:	104662878(CBR4)

RBB:	108522861(CBR4)

TFN:	117086108(CBR4)

PTEH:

111537906 111553776(CBR4)

CANG:

105524399(CBR4)

CJC:	100406542(CBR4)

SBQ:	101044331(CBR4)

CIMI:

108288581(CBR4)

CSYR:

103268287(CBR4)

MMUR:

105874616(CBR4)

LCAT:

123638707(CBR4)

PCOQ:

105820594(CBR4)

OGA:	100949547(CBR4)

MMU:	234309(Cbr4)

MCAL:

110300675(Cbr4)

MPAH:

110336964(Cbr4)

RNO:	359725(Cbr4)

MCOC:

116069352(Cbr4)

ANU:	117721251(Cbr4)

MUN:	110563483(Cbr4)

CGE:	100758439(Cbr4)

MAUA:

101834556(Cbr4)

PROB:

127220591(Cbr4)

PLEU:

114701098(Cbr4)

MORG:

121462510(Cbr4)

MFOT:

126513450

AAMP:

119812401(Cbr4)

NGI:	103727143(Cbr4)

HGL:	101701861(Cbr4)

CPOC:

100729071(Cbr4)

CCAN:

109681810(Cbr4)

DORD:

105991856(Cbr4)

DSP:	122125596(Cbr4)

PLOP:

125339451(Cbr4)

NCAR:

124972022 124983502

OCU:

100346176

OPI:	101520637(CBR4)

TUP:	102488343(CBR4)

GVR:	103588792(CBR4)

CFA:	477352(CBR4)

CLUD:

112669588(CBR4)

VVP:	112918575(CBR4)

VLG:	121497078(CBR4)

NPO:	129504557(CBR4)

AML:	100482588(CBR4)

UMR:	103658144(CBR4)

UAH:	113245456 113245503

UAR:	123793166(CBR4)

ELK:

111156121

LLV:

125093057

MPUF:

101684055(CBR4)

NVS:	122889568(CBR4)

ORO:	101383337(CBR4)

EJU:	114210197(CBR4)

ZCA:	113925733(CBR4)

MLX:	118022170(CBR4)

NSU:	110588545(CBR4)

LWW:	102743559(CBR4)

FCA:	101094263(CBR4)

PYU:	121027452(CBR4)

PCOO:

112858641(CBR4)

PBG:	122474786(CBR4)

LRUF:

124520576

PTG:	102953494(CBR4)

PPAD:

109262437(CBR4)

PUC:

125923192

AJU:

106988794

HHV:	120244766(CBR4)

BTA:	533020(CBR4)

BOM:	102267961(CBR4)

BIU:	109562751(CBR4)

BBUB:

102392346(CBR4)

BBIS:

104997851(CBR4)

CHX:	102168724(CBR4)

OAS:	101111166 101122167(CBR4)

BTAX:

128052185(CBR4)

ODA:	120854407(CBR4)

CCAD:

122453123(CBR4)

MBEZ:

129557463(CBR4)

SSC:	100153608(CBR4)

CFR:	102518024(CBR4)

CBAI:

105073355(CBR4)

CDK:	105101613(CBR4)

VPC:	102537023(CBR4)

BACU:

103016221(CBR4)

LVE:	103073947(CBR4)

OOR:	101276282(CBR4)

DLE:	111185339(CBR4)

PCAD:

102980886(CBR4)

PSIU:

116755441(CBR4)

NASI:

112403188(CBR4)

ECB:	100061412(CBR4)

EPZ:	103550083(CBR4)

EAI:	106837729(CBR4)

MYB:	102252651(CBR4)

MYD:	102763051(CBR4)

MMYO:

118659072(CBR4)

MLF:	102418604 102419857(CBR4)

MNA:	107527526(CBR4)

PKL:	118711733(CBR4)

HAI:	109394918(CBR4)

DRO:	112312696(CBR4)

SHON:

118995336(CBR4)

AJM:	119045612(CBR4)

PDIC:

114503124(CBR4)

PHAS:

123813949

MMF:	118615444(CBR4)

RFQ:	117037424(CBR4)

PALE:

102888794(CBR4)

PGIG:

120613488(CBR4)

PVP:	105292166(CBR4)

RAY:	107512540(CBR4)

MJV:	108408743 108410130

TOD:	119257962(CBR4)

SARA:

101542050(CBR4)

LAV:	100676246(CBR4)

TMU:

101357516

ETF:	101655663(CBR4)

DNM:

101428805

MDO:	100015144(CBR4)

GAS:	123251035(CBR4)

SHR:	100917532(CBR4)

AFZ:

127539803

PCW:	110215991(CBR4)

OAA:	114815528(CBR4)

GGA:	422435(CBR4)

PCOC:

116226084(CBR4)

MGP:	100539549(CBR4)

CJO:	107313084(CBR4)

TPAI:

128084264(CBR4)

NMEL:

110397753(CBR4)

APLA:

101804632(CBR4)

ACYG:

106032341(CBR4)

AFUL:

116488750(CBR4)

TGU:	100225160(CBR4)

LSR:	110467591(CBR4)

SCAN:

103825929(CBR4)

PMOA:

120497908(CBR4)

OTC:	121331406(CBR4)

PRUF:

121360181(CBR4)

GFR:	102039682(CBR4)

FAB:	101813892(CBR4)

PHI:	102112601(CBR4)

PMAJ:

107203494(CBR4)

CCAE:

111927895(CBR4)

CCW:	104690536(CBR4)

CBRC:

103619998(CBR4)

ETL:	114064977(CBR4)

ZAB:	102062548(CBR4)

ACHL:

103807003(CBR4)

SVG:	106854535(CBR4)

FPG:	101913525 101915340(CBR4)

FCH:	102045843 102046622

CLV:	102089643(CBR4)

EGZ:	104123107(CBR4)

NNI:	104021262(CBR4)

PLET:

104614951(CBR4)

PCRI:

104031021(CBR4)

PCAO:

104043627(CBR4)

ACUN:

113479413(CBR4)

TALA:

104356221(CBR4)

PADL:

103922556(CBR4)

AFOR:

103893277(CBR4)

ACHC:

115345329(CBR4)

HALD:

104324253(CBR4)

HLE:	104833345(CBR4)

AGEN:

126035440

GCL:

127015819

CCRI:

104157773(CBR4)

CSTI:

104549883(CBR4)

EHS:	104515497(CBR4)

CMAC:

104481512(CBR4)

MUI:	104548319(CBR4)

BREG:

104637123(CBR4)

FGA:	104069900(CBR4)

GSTE:

104250979(CBR4)

LDI:	104340371(CBR4)

MNB:	103773938(CBR4)

OHA:	104334800(CBR4)

NNT:	104403463(CBR4)

SHAB:

115610390(CBR4)

DPUB:

104306718(CBR4)

PGUU:

104458393(CBR4)

ACAR:

104517944(CBR4)

CPEA:

104387223(CBR4)

AVIT:

104275699(CBR4)

CVF:	104294158(CBR4)

CUCA:

104063016(CBR4)

TEO:	104380327(CBR4)

BRHI:

104491659(CBR4)

AAM:	106484084(CBR4)

AROW:

112971086(CBR4)

NPD:	112955409(CBR4)

TGT:	104580680(CBR4)

DNE:	112997057(CBR4)

SCAM:

104145587(CBR4)

ASN:	102387018(CBR4)

AMJ:	102559510(CBR4)

CPOO:

109309739(CBR4)

GGN:	109300887(CBR4)

PSS:	102446718(CBR4)

CMY:	102931938(CBR4)

DCC:	119854818(CBR4)

CPIC:

101938787(CBR4)

TST:	117877592(CBR4)

CABI:

116838455(CBR4)

MRV:	120406831(CBR4)

ACS:	100552602(cbr4)

PVT:	110085385(CBR4)

PBI:	103053921(CBR4)

PMUR:

107287978(CBR4)

CTIG:

120300461(CBR4)

TSR:	106546804(CBR4)

PGUT:

117680131(CBR4)

PTEX:

113435728(CBR4)

NSS:	113419474(CBR4)

VKO:	123023745(CBR4)

PMUA:

114604160(CBR4)

ZVI:	118084430(CBR4)

HCG:	128328116(CBR4)

GJA:	107114665(CBR4) 107119361

STOW:

125440262(CBR4)

XLA:	108706632 414681(cbr4.L)

XTR:	493259(cbr4)

NPR:	108789901(CBR4)

RTEM:

120920748(CBR4)

BBUF:

120991749(CBR4)

BGAR:

122931953(CBR4)

DRE:	402954(cbr4)

SRX:	107718413 107755259

SANH:

107665353 107683981

SGH:	107597475 107601946

CAUA:

113037773(cbr4)

CGIB:

127983810

PTET:

122324524(cbr4)

LROH:

127182743(cbr4)

PPRM:

120493569(cbr4)

MAMB:

125278025(cbr4)

CIDE:

127501799

MASI:

127410004

IPU:	100528833(cbr4)

PHYP:

113546832(cbr4)

SMEO:

124377292(cbr4)

TFD:	113653663(cbr4)

AMEX:

103036748(cbr4)

CMAO:

118815366(cbr4)

EEE:	113581035(cbr4)

CHAR:

105895100(cbr4)

TRU:	101071530(cbr4)

TNG:	GSTEN00032792G001

LCO:	104919073(cbr4)

CGOB:

115004591(cbr4)

ELY:	117253673(cbr4)

EFO:	125895461(cbr4)

PLEP:

121941226(cbr4)

SLUC:

116058741(cbr4)

ECRA:

117950265(cbr4)

ESP:	116695325(cbr4)

PFLV:

114561022(cbr4)

GAT:	120823875(cbr4)

PPUG:

119216782(cbr4)

MSAM:

119901086(cbr4)

SCHU:

122877768(cbr4)

CUD:	121512548(cbr4)

ALAT:

119027999(cbr4)

MZE:	101485831(cbr4)

ONL:	100693322(cbr4)

OAU:	116331246(cbr4)

OLA:	101155177(cbr4)

OML:	112136902(cbr4)

XMA:	102227629(cbr4)

XCO:	114151543(cbr4)

XHE:	116725538(cbr4)

PRET:

103463859(cbr4)

PFOR:

103137137(cbr4)

PLAI:

106954442(cbr4)

PMEI:

106930387(cbr4)

GAF:	122838989(cbr4)

CVG:	107103725(cbr4)

CTUL:

119779374(cbr4)

GMU:	124874092(cbr4)

NFU:	107396096(cbr4)

KMR:	108240189(cbr4)

ALIM:

106526069(cbr4)

NWH:	119430868(cbr4)

AOCE:

111566275(cbr4)

MCEP:

125009471(cbr4)

CSEM:

103398860(cbr4)

POV:	109625678(cbr4)

SSEN:

122780533(cbr4)

HHIP:

117759870(cbr4)

HSP:	118121050(cbr4)

LCF:

108878901

SDU:	111226332(cbr4)

SLAL:

111660160(cbr4)

XGL:	120790497(cbr4)

BPEC:

110154851(cbr4)

MALB:

109962115(cbr4)

BSPL:

114853188(cbr4)

SASA:

100196741(cbr4)

STRU:

115192400(cbr4)

OTW:	112248991 112251591(cbr4)

OMY:	110521654 110522998(cbr4)

OGO:	123997220(cbr4) 124037841

ONE:	115145106(cbr4)

SALP:

111972299(cbr4) 111975311

SNH:	120052573 120054913(cbr4)

CCLU:

121532670(cbr4) 121540172

ELS:	105011811(cbr4)

SFM:

108922789

PKI:	111850053(cbr4)

AANG:

118226032(cbr4)

LOC:	102692274(cbr4)

PSPA:

121300352(cbr4)

ARUT:

117421004(cbr4)

PSEX:

120527584(cbr4)

LCM:	102350295(CBR4)

BFO:

BBEL:

AJC:

SKO:

DSV:

RSAN:

RMP:

VDE:

VJA:

DPTE:

DFR:

CSCU:

LPOL:

LAK:

EPA:

ATEN:

ADF:	107332538 107337853

AMIL:

114952737

PTKZ:

JDV02_006064

» show all

Reference

PMID:19000905

Authors

Endo S, Matsunaga T, Kitade Y, Ohno S, Tajima K, El-Kabbani O, Hara A

Title

Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase.

Journal

Biochem Biophys Res Commun 377:1326-30 (2008)
DOI:10.1016/j.bbrc.2008.11.003

Reference

PMID:19571038

Authors

Chen Z, Kastaniotis AJ, Miinalainen IJ, Rajaram V, Wierenga RK, Hiltunen JK

Title

17beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS.

Journal

FASEB J 23:3682-91 (2009)
DOI:10.1096/fj.09-133587

Sequence

[hsa:84869]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (11)   
   KEGG REACTION (8)   
   KEGG RCLASS (3)   
Gene (460)   
   KEGG GENES (370)   
   KEGG MGENES (44)   
   RefGene (43)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (482)   

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