KEGG   ORTHOLOGY: K11627
Entry
K11627                      KO                                     
Symbol
pylS
Name
pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
Pathway
map00970  Aminoacyl-tRNA biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    K11627  pylS; pyrrolysyl-tRNA synthetase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K11627  pylS; pyrrolysyl-tRNA synthetase
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis
    K11627  pylS; pyrrolysyl-tRNA synthetase
Enzymes [BR:ko01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.26  pyrrolysine---tRNAPyl ligase
     K11627  pylS; pyrrolysyl-tRNA synthetase
Amino acid related enzymes [BR:ko01007]
 Aminoacyl-tRNA synthetase
  Class II (A)
   K11627  pylS; pyrrolysyl-tRNA synthetase
Transfer RNA biogenesis [BR:ko03016]
 Prokaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Other AARSs
    K11627  pylS; pyrrolysyl-tRNA synthetase
Aminoacyl-tRNA synthetases [br01613.html]
 Aminoacyl-tRNA synthetases in prokaryotes and eukaryotes
  K11627
Other DBs
RN: R08578
GO: 0043767
Genes
MBA: Mbar_A0839
MBY: MSBRM_0155
MBW: MSBRW_0162
MBAR: MSBR2_2226
MBAK: MSBR3_2277
MAC: MA_0155
MMA: MM_1445
MMJ: MSMAS_3219
MMAC: MSMAC_3241
MVC: MSVAZ_3361
METM: MSMTP_3119
MTHR: MSTHT_1934
MTHE: MSTHC_1349
MHOR: MSHOH_3965
MBU: Mbur_2086
MMET: MCMEM_0285
MMH: Mmah_0283
MHAZ: BHR79_02105(pylS)
MPY: Mpsy_1721(pylS)
MZI: HWN40_00965(pylS)
 » show all
Reference
  Authors
Li WT, Mahapatra A, Longstaff DG, Bechtel J, Zhao G, Kang PT, Chan MK, Krzycki JA
  Title
Specificity of pyrrolysyl-tRNA synthetase for pyrrolysine and pyrrolysine analogs.
  Journal
J Mol Biol 385:1156-64 (2009)
DOI:10.1016/j.jmb.2008.11.032
Reference
  Authors
Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D
  Title
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine.
  Journal
Proc Natl Acad Sci U S A 101:12450-4 (2004)
DOI:10.1073/pnas.0405362101
  Sequence

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