KEGG   ORTHOLOGY: K12093
Entry
K12093                      KO                                     

Name
cag8
Definition
cag pathogenicity island protein 8
Pathway
ko05120  Epithelial cell signaling in Helicobacter pylori infection
Module
M00564  Helicobacter pylori pathogenicity signature, cagA pathogenicity island
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K12093  cag8; cag pathogenicity island protein 8
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02044 Secretion system
    K12093  cag8; cag pathogenicity island protein 8
Secretion system [BR:ko02044]
 Type IV secretion system
  Cag pathogenicity island (PAI) protein
   K12093  cag8; cag pathogenicity island protein 8
Other DBs
COG: COG3504
TC: 3.A.7.12.1
Genes
HPY: HP0528
HEO: C694_02725
HPJ: jhp_0477(orf15)
HPA: HPAG1_0504
HPS: HPSH_04280
HHP: HPSH112_04405
HHQ: HPSH169_02705
HHR: HPSH417_02520
HPG: HPG27_487(cagX)
HPP: HPP12_0535(cagX)
HPL: HPB8_715(cagX)
HEF: HPF16_0827(cagX)
HPF: HPF30_0796(cagX)
HEQ: HPF32_0507(cagX)
HEX: HPF57_0558(cagX)
HPZ: HPKB_0814
HPV: HPV225_0523(cagX)
HPD: KHP_0791(cag8)
HEY: MWE_0994
HPYO: HPOK113_0549(cagX)
HPYL: HPOK310_0801(cagX)
HPYR: K747_13090
HPYI: K750_04130
HPYU: K751_03265
HPYM: K749_01340
HEB: U063_0836
HEZ: U064_0839
 » show all
Reference
  Authors
Kutter S, Buhrdorf R, Haas J, Schneider-Brachert W, Haas R, Fischer W
  Title
Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies.
  Journal
J Bacteriol 190:2161-71 (2008)
DOI:10.1128/JB.01341-07
Reference
  Authors
Fischer W, Puls J, Buhrdorf R, Gebert B, Odenbreit S, Haas R
  Title
Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8.
  Journal
Mol Microbiol 42:1337-48 (2001)
DOI:10.1046/j.1365-2958.2001.02714.x
  Sequence
[hpy:HP0528]

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