KEGG   ORTHOLOGY: K12407
Entry
K12407                      KO                                     

Symbol
GCK
Name
glucokinase [EC:2.7.1.2]
Pathway
map00010  Glycolysis / Gluconeogenesis
map00052  Galactose metabolism
map00500  Starch and sucrose metabolism
map00520  Amino sugar and nucleotide sugar metabolism
map00521  Streptomycin biosynthesis
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01250  Biosynthesis of nucleotide sugars
map04910  Insulin signaling pathway
map04911  Insulin secretion
map04917  Prolactin signaling pathway
map04922  Glucagon signaling pathway
map04930  Type II diabetes mellitus
map04950  Maturity onset diabetes of the young
map05230  Central carbon metabolism in cancer
Module
M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Disease
H00410  Maturity onset diabetes of the young (MODY)
H00512  Permanent neonatal diabetes mellitus
H01267  Familial hyperinsulinemic hypoglycemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K12407  GCK; glucokinase
   00052 Galactose metabolism
    K12407  GCK; glucokinase
   00500 Starch and sucrose metabolism
    K12407  GCK; glucokinase
   00520 Amino sugar and nucleotide sugar metabolism
    K12407  GCK; glucokinase
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    K12407  GCK; glucokinase
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K12407  GCK; glucokinase
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K12407  GCK; glucokinase
   04910 Insulin signaling pathway
    K12407  GCK; glucokinase
   04922 Glucagon signaling pathway
    K12407  GCK; glucokinase
   04917 Prolactin signaling pathway
    K12407  GCK; glucokinase
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    K12407  GCK; glucokinase
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K12407  GCK; glucokinase
   04950 Maturity onset diabetes of the young
    K12407  GCK; glucokinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     K12407  GCK; glucokinase
Other DBs
RN: R00299 R01600 R01786
GO: 0004340
Genes
HSA: 2645(GCK)
PTR: 737923(GCK)
PPS: 100979621(GCK)
GGO: 101138839(GCK)
PON: 100459152(GCK)
NLE: 100591653(GCK)
MCC: 699728(GCK)
MCF: 102127599(GCK)
CSAB: 103226145(GCK)
CATY: 105596912(GCK)
PANU: 101010803(GCK)
RRO: 104671144(GCK)
RBB: 108544024(GCK)
TFN: 117073299(GCK)
PTEH: 111552288(GCK)
CJC: 100409392(GCK)
SBQ: 101027980(GCK)
MMUR: 105858409(GCK)
MMU: 103988(Gck)
MCAL: 110305090(Gck)
MPAH: 110330598(Gck)
RNO: 24385(Gck)
MCOC: 116068614(Gck)
MUN: 110546096(Gck)
CGE: 100763110(Gck)
PLEU: 114693980(Gck)
NGI: 103734982(Gck)
HGL: 101721664(Gck)
CCAN: 109685901(Gck)
OCU: 100341946(GCK)
OPI: 101521696(GCK)
TUP: 102492140(GCK)
CFA: 606490(GCK)
VVP: 112911707(GCK)
VLG: 121489105(GCK)
AML: 100475738(GCK)
UMR: 103674684(GCK)
UAH: 113257909(GCK)
ORO: 101383256(GCK)
MPUF: 101680613(GCK)
EJU: 114202278(GCK)
MLX: 118024577(GCK)
FCA: 100037406(GCK)
PYU: 121016941(GCK)
PBG: 122487627(GCK)
PTG: 102965436(GCK)
PPAD: 109267871(GCK)
AJU: 106968236(GCK)
HHV: 120238910(GCK)
BTA: 616576(GCK)
BOM: 102277785(GCK)
BIU: 109557544(GCK)
BBUB: 102398970(GCK)
CHX: 102185429(GCK)
OAS: 101117412(GCK)
ODA: 120877500(GCK)
CCAD: 122438530(GCK)
SSC: 100514142(GCK)
CFR: 102506850(GCK)
CBAI: 105080693(GCK)
CDK: 105092330(GCK)
BACU: 103004735(GCK)
LVE: 103074175(GCK)
OOR: 101286839(GCK)
DLE: 111184513(GCK)
PCAD: 102974757(GCK)
ECB: 100051836
EPZ: 103554943(GCK)
EAI: 106822865
MYB: 102261259(GCK)
MYD: 102757162(GCK)
MMYO: 118665862(GCK)
MNA: 107542054(GCK)
HAI: 109373004(GCK)
DRO: 112306978(GCK)
SHON: 118983459(GCK)
AJM: 119052877
MMF: 118619794(GCK)
PALE: 102884319(GCK)
PGIG: 120589556(GCK)
RAY: 107512383(GCK)
MJV: 108394025(GCK)
TOD: 119253142(GCK)
LAV: 100658238(GCK)
TMU: 101346854
MDO: 100030125(GCK)
SHR: 100918168(GCK)
PCW: 110206409(GCK)
GGA: 430370(GCK)
PCOC: 116231330(GCK)
MGP: 100546168(GCK)
CJO: 107323664(GCK)
NMEL: 110387119(GCK)
TGU: 100222236(GCK)
LSR: 110478293(GCK)
SCAN: 108963196(GCK)
PMOA: 120504999(GCK)
OTC: 121346673(GCK)
PRUF: 121359823(GCK)
GFR: 102040748(GCK)
FAB: 101821944(GCK)
PHI: 102105464(GCK)
PMAJ: 107213875(GCK)
CCAE: 111938902(GCK)
CCW: 104683184(GCK)
ETL: 114071694(GCK)
FPG: 101920472(GCK)
FCH: 102058018(GCK)
CLV: 102084067(GCK)
EGZ: 104122939(GCK)
NNI: 104022603(GCK)
AAM: 106494575(GCK)
AROW: 112971124(GCK)
NPD: 112950360(GCK)
DNE: 112995687(GCK)
ASN: 102373336(GCK)
AMJ: 102558588(GCK)
PSS: 102457711(GCK)
CMY: 102932759(GCK)
CPIC: 101935155(GCK)
TST: 117872865(GCK)
CABI: 116815260(GCK)
ACS: 100554306(gck)
PVT: 110084342(GCK)
PBI: 103062255(GCK)
PMUR: 107286239(GCK)
TSR: 106547695(GCK)
PGUT: 117677051(GCK)
PMUA: 114585937(GCK)
ZVI: 118096834(GCK)
GJA: 107117392(GCK)
XLA: 108712732(gck.S) 378602(gck.L)
XTR: 100124905(gck)
NPR: 108796074(GCK)
DRE: 751668(gck)
IPU: 108265751(gck)
PHYP: 113546126(gck)
AMEX: 103039737(gck)
EEE: 113588677(gck)
TRU: 101063910(gck)
LCO: 104922970(gck)
NCC: 104956790(gck)
CGOB: 115013132(gck)
ELY: 117252119(gck)
PLEP: 121944522(gck)
SLUC: 116054258(gck)
ECRA: 117945488(gck)
PFLV: 114555604(gck)
GAT: 120830946(gck)
PPUG: 119225324(gck)
MSAM: 119891486(gck)
MZE: 101465626(gck)
ONL: 100695414(gck)
OAU: 116310976(gck)
OLA: 101168372(gck)
OML: 112148443(gck)
XMA: 102229323(gck)
XCO: 114154034(gck)
XHE: 116729225(gck)
PRET: 103470005(gck)
CVG: 107089653(gck)
CTUL: 119778162(gck)
NFU: 107394278(gck)
KMR: 108233647(gck)
ALIM: 106519906(gck)
AOCE: 111567820(gck)
CSEM: 103397747(gck)
POV: 109637065(gck)
LCF: 108881204(gck)
SDU: 111236443(gck)
SLAL: 111654902(gck)
XGL: 120805335(gck)
HCQ: 109526325(gck)
BPEC: 110153979(gck)
MALB: 109956568(gck)
SASA: 106580581(gk) 106585167
SALP: 111957731 111974003(gck)
ELS: 105014407(gck)
SFM: 108932222 108940338(gck)
PKI: 111861171(gck)
AANG: 118206764(gck) 118212896
LOC: 102694132(gck)
ARUT: 117397918(gck)
LCM: 102364718(GCK)
CMK: 103187782(gck)
RTP: 109932925
API: 103310688
 » show all
Reference
  Authors
Iynedjian PB
  Title
Molecular physiology of mammalian glucokinase.
  Journal
Cell Mol Life Sci 66:27-42 (2009)
DOI:10.1007/s00018-008-8322-9

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