KEGG   ORTHOLOGY: K12645
Entry
K12645                      KO                                     
Symbol
CYP170A
Name
epi-isozizaene 5-monooxygenase / beta-farnesene synthase [EC:1.14.15.39 4.2.3.47]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K12645  CYP170A; epi-isozizaene 5-monooxygenase / beta-farnesene synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K12645  CYP170A; epi-isozizaene 5-monooxygenase / beta-farnesene synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.39  epi-isozizaene 5-monooxygenase
     K12645  CYP170A; epi-isozizaene 5-monooxygenase / beta-farnesene synthase
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.47  beta-farnesene synthase
     K12645  CYP170A; epi-isozizaene 5-monooxygenase / beta-farnesene synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP170 family
   K12645  CYP170A; epi-isozizaene 5-monooxygenase / beta-farnesene synthase
Other DBs
RN: R08695 R08851 R08852 R08853 R08854 R10072
COG: COG2124
Genes
SCO: SCO5223(SC7E4.20)
SALB: XNR_1579
SMA: SAVERM_3031(cyp14)
SHY: SHJG_6336
SHO: SHJGH_6097
SDV: BN159_3154
SALS: SLNWT_2071
SCI: B446_24615
SLV: SLIV_12250
SGU: SGLAU_22465
SLE: sle_25170(sle_25170)
STRD: NI25_13050
SFK: KY5_5349
SRJ: SRO_2585
 » show all
Reference
PMID:18234666 (CYP170A1)
  Authors
Zhao B, Lin X, Lei L, Lamb DC, Kelly SL, Waterman MR, Cane DE
  Title
Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2).
  Journal
J Biol Chem 283:8183-9 (2008)
DOI:10.1074/jbc.M710421200
  Sequence
[sco:SCO5223]

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