novR (gene name)
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
4-hydroxy-3-prenylmandelate:oxygen oxidoreductase (4-hydroxy-3-prenylbenzoate forming)
4-hydroxy-3-prenylmandelate + O2 = 4-hydroxy-3-prenylbenzoate + CO2 + H2O [RN:
Isolated from the bacterium Streptomyces roseochromogenes DS 12976. A bifunctional enzyme involved in clorobiocin biosynthesis that also catalyses the activity of EC
, 4-hydroxy-3-prenylphenylpyruvate oxygenase.
EC 22.214.171.124 created 2017
ec01110 Biosynthesis of secondary metabolites
K12708 4-hydroxy-3-prenylphenylpyruvate oxygenase / 4-hydroxy-3-prenylbenzoate synthase
Pojer F, Kahlich R, Kammerer B, Li SM, Heide L.
CloR, a bifunctional non-heme iron oxygenase involved in clorobiocin biosynthesis.