KEGG   ORTHOLOGY: K12902
Entry
K12902            Tight     KO                                     

Name
fom3
Definition
phosphonoacetaldehyde methylase [EC:2.1.1.308]
Pathway
ko00998  Biosynthesis of various secondary metabolites - part 2
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various secondary metabolites - part 2
    K12902  fom3; phosphonoacetaldehyde methylase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.308  cytidylyl-2-hydroxyethylphosphonate methyltransferase
     K12902  fom3; phosphonoacetaldehyde methylase
Other DBs
RN: R08862 R12497
Genes
AG: ACG70826(fom3) BAA32490(fom3)
Reference
PMID:7789803
  Authors
Hidaka T, Hidaka M, Kuzuyama T, Seto H
  Title
Sequence of a P-methyltransferase-encoding gene isolated from a bialaphos-producing Streptomyces hygroscopicus.
  Journal
Gene 158:149-50 (1995)
DOI:10.1016/0378-1119(95)00101-B
  Sequence
Reference
  Authors
Metcalf WW, van der Donk WA
  Title
Biosynthesis of phosphonic and phosphinic acid natural products.
  Journal
Annu Rev Biochem 78:65-94 (2009)
DOI:10.1146/annurev.biochem.78.091707.100215
Reference
  Authors
Woodyer RD, Li G, Zhao H, van der Donk WA
  Title
New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin.
  Journal
Chem Commun (Camb) 359-61 (2007)
DOI:10.1039/b614678c
  Sequence

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