KEGG   ORTHOLOGY: K13066
Entry
K13066                      KO                                     

Symbol
COMT
Name
caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase [EC:2.1.1.68 2.1.1.4]
Pathway
map00380  Tryptophan metabolism
map00940  Phenylpropanoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00936  Melatonin biosynthesis, plants, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K13066  COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase
  09110 Biosynthesis of other secondary metabolites
   00940 Phenylpropanoid biosynthesis
    K13066  COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.4  acetylserotonin O-methyltransferase
     K13066  COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase
    2.1.1.68  caffeate O-methyltransferase
     K13066  COMT; caffeic acid 3-O-methyltransferase / acetylserotonin O-methyltransferase
Other DBs
RN: R02379 R03130 R03366 R06574 R06575 R06576 R06577
COG: COG0500
GO: 0047763 0017096
Genes
ATH: AT5G54160(OMT1)
ALY: 9302094 9302099 9303555 9303558
CRB: 17876808 17896611
CSAT: 104703789 104717445 104722135 104725937 104729294 104730586 104730602 104752845 104761441
EUS: EUTSA_v10013896mg EUTSA_v10013897mg EUTSA_v10013908mg EUTSA_v10025520mg EUTSA_v10025522mg EUTSA_v10027501mg
BRP: 103844876 103844878 103851985 103857055 103861716 103868698
BNA: 106356003 106373206 106374490 106383910 106385406 106392944 106409594 106418605 106432400 106434499 106434512 106437132 106437143 106437536 106444684 111205367
BOE: 106296210 106304347 106314910 106318901 106326817 106332463 106336119
RSZ: 108840420 108842003 108847745 108849034 108855334
THJ: 104799941 104799942 104799943 104802099 104804741 104811887 104813820
CPAP: 110823164
LJA: Lj1g3v1079700.1(Lj1g3v1079700.1) Lj1g3v5060810.2(Lj1g3v5060810.2) Lj2g3v3339490.1(Lj2g3v3339490.1)
ADU: 107470102
AIP: 107622793
OSA: 4344702
DOSA: Os08t0157500-01(Os08g0157500)
OBR: 102717362
SBI: 8069622
ZMA: 100125646
SITA: 101765311
PHAI: 112897072
ATR: 18424568
SMO: SELMODRAFT_450944(COMT1-1) SELMODRAFT_450945(COMT1-2)
 » show all
Reference
  Authors
Zubieta C, Kota P, Ferrer JL, Dixon RA, Noel JP
  Title
Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase.
  Journal
Plant Cell 14:1265-77 (2002)
DOI:10.1105/tpc.001412
  Sequence
Reference
  Authors
Byeon Y, Lee HY, Lee K, Back K
  Title
Caffeic acid O-methyltransferase is involved in the synthesis of melatonin by methylating N-acetylserotonin in Arabidopsis.
  Journal
J Pineal Res 57:219-27 (2014)
DOI:10.1111/jpi.12160
  Sequence
[ath:AT5G54160]

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