KEGG   ORTHOLOGY: K13085
Entry
K13085                      KO                                     

Symbol
ipgD, sopB
Name
phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
Pathway
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05132  Salmonella infection
Network
nt06110  MAPK signaling (viruses and bacteria)
nt06125  Membrane trafficking (bacteria)
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
N01133  Salmonella SopB to RhoG signaling pathway
N01134  Salmonella SopB to CDC42 signaling pathway
N01303  Salmonella SopB to Early endosomal fusion
N01305  Salmonella SopB to ANXA2-S100A10-regulated actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
   05131 Shigellosis
    K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
   05100 Bacterial invasion of epithelial cells
    K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.78  phosphatidylinositol-4,5-bisphosphate 4-phosphatase
     K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Other DBs
RN: R08981
Genes
EMA: C1192_24285
STY: STY1121(sigD)
STT: t1828(sigD)
SEX: STBHUCCB_19440
SENT: TY21A_09295
STM: STM1091(sopB)
SEO: STM14_1237(sopB)
SEV: STMMW_11031
SEY: SL1344_1030(sopB)
SEM: STMDT12_C11120
SEJ: STMUK_1060(sopB)
SEB: STM474_1083(sopB)
SEF: UMN798_1133(sigD)
SETC: CFSAN001921_11720(sopB)
SENR: STMDT2_10271(sigD)
SEND: DT104_10731(sopB)
SENI: CY43_05575(sopB)
SEEN: SE451236_11305(sopB)
SPT: SPA1759(sigD)
SEK: SSPA1634
SEI: SPC_2659(sigD)
SEC: SCH_1043(sopB)
SHB: SU5_01724
SENH: CFSAN002069_03565(sopB)
SENS: Q786_04870(sopB)
SED: SeD_A1167
SEG: SG0980(sopB)
SEL: SPUL_1966(sopB)
SEGA: SPUCDC_1952(sopB)
SET: SEN0955(sopB)
SENA: AU38_04930(sopB)
SENO: AU37_04920(sopB)
SENV: AU39_04920(sopB)
SENQ: AU40_05535(sopB)
SENL: IY59_05020(sopB)
SEEC: CFSAN002050_11850(sopB)
SEEB: SEEB0189_014115(sopB)
SEEP: I137_08940(sopB)
SENE: IA1_05370(sopB)
SENC: SEET0819_12115(sopB)
SBG: SBG_0939(sopB)
SBZ: A464_1030
SBV: N643_04465(sopB)
SFL: CP0133(ipgD)
SFE: SFxv_4976(ipgD)
SSN: SSON_P095(ipgD)
SBC: SbBS512_A0166(ipgD)
SDY: SDY_P171(ipgD)
YAL: AT01_2850(sopB)
SOD: Sant_3206(sigD) Sant_3209(sigD2)
PAY: PAU_01919
PSI: S70_12925
PSX: DR96_586(sopB)
ANS: ArsFIN_43100(sopB)
VAN: VAA_02157
CHAE: CH06BL_40220(sopB_sigD)
IFL: C1H71_17665(sopB)
PPNO: DA70_11385
PPNM: LV28_19660
PVAC: HC248_01669(ipgD)
PSF: PSE_2750(ipgD)
PNL: PNK_0614(ipgD)
 » show all
Reference
  Authors
Niebuhr K, Giuriato S, Pedron T, Philpott DJ, Gaits F, Sable J, Sheetz MP, Parsot C, Sansonetti PJ, Payrastre B
  Title
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology.
  Journal
EMBO J 21:5069-78 (2002)
DOI:10.1093/emboj/cdf522
  Sequence
[sfl:CP0133]

DBGET integrated database retrieval system