KEGG   ORTHOLOGY: K13510
Entry
K13510                      KO                                     

Symbol
LPCAT1_2
Name
lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
Pathway
map00564  Glycerophospholipid metabolism
map00565  Ether lipid metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase
   00565 Ether lipid metabolism
    K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.23  1-acylglycerophosphocholine O-acyltransferase
     K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase
    2.3.1.67  1-alkylglycerophosphocholine O-acetyltransferase
     K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase
Lipid biosynthesis proteins [BR:ko01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase
Other DBs
RN: R01318 R03437 R03438 R09036
GO: 0047184 0047192
Genes
HSA: 54947(LPCAT2) 79888(LPCAT1)
PTR: 454095(LPCAT2) 461698(LPCAT1)
PPS: 100970278(LPCAT2) 100991866(LPCAT1)
GGO: 101125811(LPCAT1) 101148534(LPCAT2)
PON: 100435855(LPCAT1) 100449928(LPCAT2)
NLE: 100597870(LPCAT2) 100600471(LPCAT1)
MCC: 698605(LPCAT2) 710144(LPCAT1)
MCF: 102125601(LPCAT2) 102143549(LPCAT1)
CSAB: 103214933(LPCAT1) 103225898 103233009(LPCAT2)
CATY: 105588546(LPCAT2) 105600708(LPCAT1)
PANU: 101013454(LPCAT2) 101023156(LPCAT1)
RRO: 104668709(LPCAT1) 104671480(LPCAT2)
RBB: 108513712(LPCAT1) 108517697 108531262(LPCAT2)
TFN: 117064706(LPCAT1) 117087798(LPCAT2)
PTEH: 111528327(LPCAT1) 111541253(LPCAT2)
CJC: 100389756(LPCAT2) 100393606(LPCAT1)
SBQ: 101032098(LPCAT1) 101042520(LPCAT2)
MMUR: 105866550(LPCAT2) 105876446(LPCAT1)
MMU: 210992(Lpcat1) 270084(Lpcat2) 70902(Lpcat2b)
MCAL: 110295425 110300420(Lpcat2) 110308216(Lpcat1)
MPAH: 110328798(Lpcat1) 110330910 110337531(Lpcat2)
RNO: 100359680(Lpcat2) 289439(Lpcat2b) 361467(Lpcat1)
MCOC: 116069869(Lpcat2) 116070787 116083122(Lpcat1)
MUN: 110545177(Lpcat2) 110545378(Lpcat1) 110549066
PLEU: 114691817 114694531(Lpcat2) 114696106(Lpcat1)
NGI: 103731684(Lpcat2) 103749677(Lpcat1)
HGL: 101696607(Lpcat2) 101709594(Lpcat1)
CCAN: 109678676(Lpcat1) 109690724(Lpcat2) 109698670
OCU: 100341001(LPCAT2) 103346634(LPCAT1)
OPI: 101523274(LPCAT2) 101536460(LPCAT1)
TUP: 102469903(LPCAT1) 102483475(LPCAT2) 102490658
CFA: 488066(LPCAT1) 611330(LPCAT2)
VVP: 112929622(LPCAT2) 112935459(LPCAT1)
VLG: 121477534(LPCAT1) 121497872(LPCAT2)
AML: 100464874(LPCAT2) 100480167(LPCAT1)
UMR: 103673788(LPCAT2) 103679260(LPCAT1)
UAH: 113252250(LPCAT2) 113260704(LPCAT1)
ORO: 101362482(LPCAT1) 101377840(LPCAT2)
MPUF: 101675782(LPCAT2) 101688998(LPCAT1)
EJU: 114198552(LPCAT1) 114200575(LPCAT2)
MLX: 118006159(LPCAT1) 118023776(LPCAT2)
FCA: 101095078(LPCAT1) 101099093(LPCAT2)
PYU: 121042187(LPCAT1) 121045319(LPCAT2)
PBG: 122494217(LPCAT2) 122495706(LPCAT1)
PTG: 102959706(LPCAT2) 102971071(LPCAT1)
PPAD: 109267860(LPCAT1) 109270905(LPCAT2)
AJU: 106973282(LPCAT2) 106985126(LPCAT1)
HHV: 120235611(LPCAT1) 120238095(LPCAT2)
BTA: 514646(LPCAT2) 788450(LPCAT1)
BOM: 102265598(LPCAT1) 102268140 102269060(LPCAT2)
BIU: 109556810 109572861(LPCAT2) 109574742(LPCAT1)
BBUB: 102401383(LPCAT2) 102408396 102416465(LPCAT1)
CHX: 102178967 102184933(LPCAT2) 102186907(LPCAT1)
OAS: 101111661(LPCAT1) 101115816(LPCAT2) 101116368 101120465
ODA: 120856539 120873208(LPCAT2) 120879280(LPCAT1)
CCAD: 122420085(LPCAT2) 122436699 122454289(LPCAT1)
SSC: 100217397(LPCAT1) 100517894(LPCAT2)
CFR: 102509280(LPCAT1) 102510009(LPCAT2) 102522183
CBAI: 105065378 105075733(LPCAT2) 105081249(LPCAT1)
CDK: 105085760 105097505(LPCAT2) 105102173(LPCAT1)
BACU: 103001888(LPCAT1) 103016463(LPCAT2)
LVE: 103071483(LPCAT2) 103079269 103087358(LPCAT1)
OOR: 101275731(LPCAT2) 101288915(LPCAT1) 101289522
DLE: 111164985(LPCAT2) 111178540(LPCAT1)
PCAD: 102973278(LPCAT2) 102983136(LPCAT1)
ECB: 100060157 100061308(LPCAT2) 100071898(LPCAT1)
EPZ: 103553196(LPCAT2) 103553726 103567497(LPCAT1)
EAI: 106822468(LPCAT2) 106835899(LPCAT1) 106846498
MYB: 102244268(LPCAT1) 102245573 102259694(LPCAT2)
MYD: 102767459(LPCAT2) 102771533(LPCAT1) 102774257
MMYO: 118655993(LPCAT1) 118674095(LPCAT2) 118675464
MNA: 107525128 107536447(LPCAT1) 107543504(LPCAT2)
HAI: 109371697(LPCAT1) 109373253
DRO: 112296674(LPCAT2) 112321152(LPCAT1)
SHON: 118998659(LPCAT1) 119001109(LPCAT2)
AJM: 119043372(LPCAT1) 119046440(LPCAT2)
MMF: 118627275 118638272(LPCAT2) 118642356(LPCAT1)
PALE: 102884144(LPCAT2) 102894173 102894763(LPCAT1)
PGIG: 120583148 120586140(LPCAT1) 120617294(LPCAT2)
RAY: 107499661(LPCAT2) 107499969(LPCAT1) 107504740
MJV: 108387906(LPCAT2) 108395302 108400618(LPCAT1)
TOD: 119248905(LPCAT2) 119261020(LPCAT1)
LAV: 100659656 100675219(LPCAT2) 100675458(LPCAT1)
MDO: 100014768(LPCAT2) 100015539(LPCAT1)
SHR: 100915216(LPCAT1) 100935270(LPCAT2)
PCW: 110201208(LPCAT1) 110207504(LPCAT2)
OAA: 100074850(LPCAT1) 100077162(LPCAT2)
GGA: 415716(LPCAT2) 420974(LPCAT1)
PCOC: 116226296(LPCAT1) 116243916(LPCAT2)
MGP: 100546916(LPCAT2) 100547104(LPCAT1)
CJO: 107309445(LPCAT1) 107319184(LPCAT2)
NMEL: 110393067(LPCAT1) 110404300(LPCAT2)
APLA: 101791762(LPCAT1) 101802263(LPCAT2)
ACYG: 106043072 106045027(LPCAT1)
TGU: 100218938(LPCAT2) 100224379(LPCAT1)
LSR: 110469713(LPCAT1) 110484404(LPCAT2)
SCAN: 103816810(LPCAT2) 103825973(LPCAT1)
PMOA: 120502980(LPCAT1) 120508086(LPCAT2)
OTC: 121334057(LPCAT2) 121337753(LPCAT1)
PRUF: 121348978(LPCAT2) 121358377(LPCAT1)
GFR: 102037826(LPCAT2) 102044114(LPCAT1)
FAB: 101811593(LPCAT2) 101820727(LPCAT1)
PHI: 102106876(LPCAT2) 102107582(LPCAT1)
PMAJ: 107200159(LPCAT1) 107209745(LPCAT2)
CCAE: 111925329(LPCAT1) 111934581(LPCAT2)
CCW: 104685842(LPCAT1) 104687552(LPCAT2)
ETL: 114060384(LPCAT2) 114064048(LPCAT1)
FPG: 101911522(LPCAT2) 101912706(LPCAT1)
FCH: 102050532(LPCAT2) 102059927(LPCAT1)
CLV: 102092846(LPCAT2) 102093144(LPCAT1)
EGZ: 104125183(LPCAT2) 104128509(LPCAT1)
NNI: 104013405(LPCAT1) 104016459(LPCAT2)
ACUN: 113476828(LPCAT1) 113484431(LPCAT2)
PADL: 103914236(LPCAT2) 103922325(LPCAT1)
AAM: 106483282(LPCAT2) 106492898(LPCAT1)
AROW: 112967564(LPCAT2) 112971806(LPCAT1)
NPD: 112947680(LPCAT2) 112953159(LPCAT1)
DNE: 112979583(LPCAT1) 112984296(LPCAT2)
ASN: 102376020(LPCAT2) 102379638(LPCAT1)
AMJ: 102561877(LPCAT1) 102574060(LPCAT2)
CPOO: 109310504(LPCAT2) 109313643(LPCAT1)
GGN: 109289620(LPCAT2) 109291954(LPCAT1)
PSS: 102450224(LPCAT1) 102462907(LPCAT2)
CMY: 102930396(LPCAT1) 102931433(LPCAT2)
CPIC: 101940623(LPCAT2) 101948289(LPCAT1)
TST: 117871748(LPCAT1) 117886448(LPCAT2)
CABI: 116817007(LPCAT1) 116820816(LPCAT2)
ACS: 100557762(lpcat2) 100563014(lpcat1)
PVT: 110080886(LPCAT1) 110090095(LPCAT2)
PMUR: 107287667(LPCAT2) 107292116(LPCAT1)
TSR: 106548677(LPCAT1)
PGUT: 117662408(LPCAT1) 117670957(LPCAT2)
PMUA: 114601052(LPCAT1) 114602201(LPCAT2)
ZVI: 118087064(LPCAT2) 118090212(LPCAT1)
GJA: 107108346(LPCAT2) 107123976(LPCAT1)
XLA: 108715344(lpcat2.S) 108720037(lpcat1.S)
XTR: 100124943(lpcat2) 100487143(lpcat1)
NPR: 108795131(LPCAT1) 108797887(LPCAT2)
DRE: 101884921 553683(lpcat2) 555969(lpcat1)
IPU: 108259642(lpcat2) 108272334(lpcat1) 108272386
PHYP: 113534115 113541008(lpcat2) 113543699(lpcat1)
AMEX: 103025479(lpcat1) 103025629
NCC: 104943321(lpcat1) 104964802
CGOB: 115015892 115021607(lpcat1) 115024611(lpcat2)
ELY: 117258177(lpcat2) 117263772(lpcat1) 117265283
PLEP: 121945648 121958043(lpcat1) 121966800(lpcat2)
SLUC: 116037547(lpcat2) 116041259(lpcat1) 116049210
ECRA: 117941908(lpcat2) 117946101 117957054(lpcat1)
GAT: 120810600 120826708(lpcat1) 120833708(lpcat2)
PPUG: 119195704(lpcat2) 119197902 119218965(lpcat1)
MSAM: 119890358(lpcat2) 119897884 119907722(lpcat1)
CUD: 121512717(lpcat2) 121513496 121523238(lpcat1)
OAU: 116321795(lpcat1) 116325616(lpcat2) 116329697
OLA: 101159130(lpcat1) 101172965(lpcat2)
OML: 112143531 112160733(lpcat2)
CTUL: 119791334 119792942(lpcat1) 119795123(lpcat2)
KMR: 108232307 108238716(lpcat1) 108240272(lpcat2)
ALIM: 106517217(lpcat2) 106521611 106532379(lpcat1)
AOCE: 111566240 111569839(lpcat1) 111577724(lpcat2)
XGL: 120784167 120786940(lpcat1) 120802024(lpcat2)
MALB: 109955890(lpcat2) 109958224
SASA: 100380789(pcat2) 106562418 106570327(lpcat1)
PKI: 111832723(lpcat2) 111844666(lpcat1)
AANG: 118227630(lpcat2) 118233785(lpcat1)
LOC: 102685085(lpcat2) 102695869(lpcat1)
PSPA: 121296371(lpcat2) 121312866 121314775(lpcat1)
LCM: 102350271(LPCAT2) 102364428(LPCAT1)
CMK: 103176103(lpcat2) 103184820(lpcat1)
RTP: 109920816(lpcat1) 109921945(lpcat2)
BFO: 118417390
BBEL: 109473681
SCLV: 120341691
SPU: 579107
APLC: 110980052
SKO: 102809674
DME: Dmel_CG32699(LPCAT)
DER: 6549790
DSE: 6617467
DSI: Dsimw501_GD16057(Dsim_GD16057)
DAN: 6505285
DSR: 110179381
DPE: 6597378
DMN: 108154418
DWI: 6649046
DGR: 6564829
DAZ: 108618902
DNV: 108656356
DHE: 111592358
DVI: 6632070
CCAT: 101449550
BOD: 106616326
MDE: 101890953
SCAC: 106081782
LCQ: 111678611
AAG: 5570702
CPII: 120419615
AME: 550970
ACER: 107999391
BIM: 100741953
BBIF: 117209760
BVK: 117235241
BVAN: 117158732
BTER: 100652042
CCAL: 108629434
OBB: 114876892
MGEN: 117221792
NMEA: 116424192
CGIG: 122397050
SOC: 105208206
MPHA: 105839855
AEC: 105145868
ACEP: 105619137
PBAR: 105432762
VEM: 105562783
HST: 105189494
DQU: 106748929
CFO: 105249392
LHU: 105679165
PGC: 109855182
OBO: 105274734
PCF: 106784843
NVI: 100120270
CSOL: 105367842
TPRE: 106651598
MDL: 103573992
FAS: 105265460
DAM: 107036526
CCIN: 107274893
TCA: 657636
DPA: 109534524
ATD: 109605346
AGB: 108913561
LDC: 111513332
NVL: 108565066
APLN: 108745174
PPYR: 116178072
BMOR: 101742486
BMAN: 114242230
MSEX: 115452829
BANY: 112046784
PMAC: 106716089
PPOT: 106101668
PXU: 106121519
PRAP: 111003489
ZCE: 119840798
HAW: 110375504
TNL: 113507517
API: 100169605
DNX: 107161663
AGS: 114130183
RMD: 113552822
BTAB: 109041084
DCI: 103524733
CLEC: 106665896
HHAL: 106685870
NLU: 111047308
FOC: 113209341
ZNE: 110838403
CSEC: 111872410
FCD: 110855863
DMK: 116924529
PVM: 113827909
HAME: 121861561
HAZT: 108673513
DSV: 119436025
RSAN: 119373476
RMP: 119177001
VDE: 111243487
VJA: 111271280
PTEP: 107440702
SDM: 118202036
TSP: Tsp_09580
PCAN: 112553333
BGT: 106077957
GAE: 121388534
CRG: 105349224
MYI: 110443813
PMAX: 117337178
OBI: 106881720
OSN: 115209705
EGL: EGR_10138
HMG: 101239736
AQU: 105312343
CPAP: 110819447
LJA: Lj0g3v0333919.1(Lj0g3v0333919.1) Lj5g3v0090530.1(Lj5g3v0090530.1) Lj5g3v2297830.1(Lj5g3v2297830.1) Lj5g3v2297830.2(Lj5g3v2297830.2)
DOSA: Os05t0357800-01(Os05g0357800) Os06t0712300-01(Os06g0712300)
AOF: 109821470
APRO: F751_2508
CPV: cgd5_1080
SMIN: v1.2.001286.t1(symbB.v1.2.001286.t1) v1.2.014309.t1(symbB.v1.2.014309.t1) v1.2.020999.t1(symbB.v1.2.020999.t1) v1.2.020999.t2(symbB.v1.2.020999.t2)
SPAR: SPRG_02060
 » show all
Reference
  Authors
Harayama T, Shindou H, Shimizu T
  Title
Biosynthesis of phosphatidylcholine by human lysophosphatidylcholine acyltransferase 1.
  Journal
J Lipid Res 50:1824-31 (2009)
DOI:10.1194/jlr.M800500-JLR200
Reference
  Authors
Shindou H, Hishikawa D, Nakanishi H, Harayama T, Ishii S, Taguchi R, Shimizu T
  Title
A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:LYSO-PAF acetyltransferase.
  Journal
J Biol Chem 282:6532-9 (2007)
DOI:10.1074/jbc.M609641200
  Sequence
[hsa:54947] [mmu:270084]

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