KEGG   ORTHOLOGY: K13549
Entry
K13549            Tight     KO                                     

Symbol
btrN
Name
2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent) [EC:1.1.99.38]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K13549  btrN; 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.99  With unknown physiological acceptors
    1.1.99.38  2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
     K13549  btrN; 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent)
Other DBs
RN: R08893
Genes
AG: BAE07062(btrN)
Reference
  Authors
Kudo F, Eguchi T
  Title
Biosynthetic enzymes for the aminoglycosides butirosin and neomycin.
  Journal
Methods Enzymol 459:493-519 (2009)
DOI:10.1016/S0076-6879(09)04620-5
Reference
  Authors
Yokoyama K, Numakura M, Kudo F, Ohmori D, Eguchi T
  Title
Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin.
  Journal
J Am Chem Soc 129:15147-55 (2007)
DOI:10.1021/ja072481t
  Sequence

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