KEGG   ORTHOLOGY: K13778
Entry
K13778                      KO                                     

Symbol
atuC
Name
geranyl-CoA carboxylase beta subunit [EC:6.4.1.5]
Pathway
map00281  Geraniol degradation
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00281 Geraniol degradation
    K13778  atuC; geranyl-CoA carboxylase beta subunit
Enzymes [BR:ko01000]
 6. Ligases
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.5  geranoyl-CoA carboxylase
     K13778  atuC; geranyl-CoA carboxylase beta subunit
Other DBs
RN: R03494
COG: COG4799
GO: 0047925
Genes
RGL: CS053_05360
DJI: CH75_09970
PAE: PA2888(atuC)
PAEV: N297_2991
PAEI: N296_2991
PAU: PA14_26720(mccB)
PAP: PSPA7_2266
PAG: PLES_21761(atuC)
PAF: PAM18_2075(atuC)
PNC: NCGM2_3999(mccB)
PAEB: NCGM1900_3423(mccB)
PAEP: PA1S_10970
PAEM: U769_10510
PAEL: T223_10980
PAEU: BN889_03226(atuC)
PAEG: AI22_22900
PAEC: M802_2988
PAEO: M801_2856
PMY: Pmen_2691
PMK: MDS_2027
PPSE: BN5_2435
PFL: PFL_4196(atuC)
PPRC: PFLCHA0_c42590(yngE2)
PPRO: PPC_4293(atuC)
PFS: PFLU_4394
PFC: PflA506_3698(atuC)
PFB: VO64_5142
PMAN: OU5_1497
PFW: PF1751_v1c38890(atuC)
PKC: PKB_3703(l(2)04524)
PSEM: TO66_22060
PSOS: POS17_4284(atuC)
PANR: A7J50_4072
PSET: THL1_3720
PSIL: PMA3_07225
PALL: UYA_10260
POJ: PtoMrB4_17800(atuC)
PKH: JLK41_10355(atuC)
PTY: JWV26_20545(atuC)
PATA: JWU58_09120(atuC)
PZE: HU754_020980(atuC)
PMOE: HV782_020180(atuC)
ACB: A1S_3008
ABM: ABSDF2871
ABY: ABAYE0480
ABN: AB57_3459
ABB: ABBFA_00509(accD5)
ABX: ABK1_3259
ABH: M3Q_3440
ABAD: ABD1_28970
ABAZ: P795_2365
ABAU: IX87_11735
ABAA: IX88_17980
AGU: AS4_37370(accD)
PAT: Patl_0317
MAQ: Maqu_2804
MHC: MARHY2691
MAD: HP15_2538
MARJ: MARI_02990(pccB)
SAGA: M5M_01905
CYQ: Q91_1221(accB1)
HCH: HCH_05748
ABO: ABO_0989(accD)
ADI: B5T_00490 B5T_01800(accD)
APAC: S7S_10290
RPI: Rpic_0106
REH: H16_A2144(pccB)
CNC: CNE_1c27040(pccB)
RME: Rmet_1721(pccB)
BPS: BPSS2031
BPL: BURPS1106A_A2774(accB)
BPSE: BDL_5454
BPSM: BBQ_4090
BPSU: BBN_5506
BPSD: BBX_4621
BPK: BBK_4782
BPSH: DR55_5690
BPSA: BBU_3967
BPSO: X996_5495
BUT: X994_5052
BTQ: BTQ_3584
BTJ: BTJ_4620
BTZ: BTL_5407
BTD: BTI_4955
BTV: BTHA_4795
BTHE: BTN_5078
BTHM: BTRA_5346
BTHA: DR62_5207
BTHL: BG87_5414
BOK: DM82_6350
BOC: BG90_4324
BUL: BW21_4483
RFR: Rfer_2818
AAA: Acav_0073
ACRA: BSY15_2082
VEI: Veis_2413
CTES: O987_10840
RGE: RGE_32870
MXA: MXAN_0081(accB)
CCX: COCOR_03097(accB)
BJA: blr0986(mccB)
BRA: BRADO6876
BBT: BBta_0675
BRS: S23_68200(mccB)
AOL: S58_05990
BRAD: BF49_7200
BARH: WN72_46670
BEL: BE61_03490(mccB)
RPA: RPA2143
RPB: RPB_3260
RPC: RPC_3201
RPD: RPD_2204
RPE: RPE_2254
RPT: Rpal_2435
RVA: Rvan_0552
RBM: TEF_07385
PSF: PSE_4599
SIL: SPO0578
LAQU: R2C4_13400
GAK: X907_0619
SECH: B18_27400
RCE: RC1_3533
TMO: TMO_a0454
 » show all
Reference
  Authors
Forster-Fromme K, Hoschle B, Mack C, Bott M, Armbruster W, Jendrossek D
  Title
Identification of genes and proteins necessary for catabolism of acyclic terpenes and leucine/isovalerate in Pseudomonas aeruginosa.
  Journal
Appl Environ Microbiol 72:4819-28 (2006)
DOI:10.1128/AEM.00853-06
  Sequence
[pae:PA2888]

KEGG   ORTHOLOGY: K13777
Entry
K13777                      KO                                     

Symbol
atuF
Name
geranyl-CoA carboxylase alpha subunit [EC:6.4.1.5]
Pathway
map00281  Geraniol degradation
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00281 Geraniol degradation
    K13777  atuF; geranyl-CoA carboxylase alpha subunit
Enzymes [BR:ko01000]
 6. Ligases
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.5  geranoyl-CoA carboxylase
     K13777  atuF; geranyl-CoA carboxylase alpha subunit
Other DBs
RN: R03494
COG: COG4770
GO: 0047925
Genes
RGL: CS053_05370
DJI: CH75_09960
PAE: PA2891(atuF)
PAEV: N297_2994
PAEI: N296_2994
PAU: PA14_26670
PAP: PSPA7_2263
PAG: PLES_21731(atuF)
PAF: PAM18_2072(atuF)
PNC: NCGM2_4002
PAEP: PA1S_10955
PAEM: U769_10495
PAEL: T223_10965
PAEU: BN889_03229(atuF)
PAEG: AI22_22915
PAEC: M802_2991
PAEO: M801_2859
PMY: Pmen_2694
PMK: MDS_2024
PPSE: BN5_2438
PCQ: PcP3B5_19970(accA1_1)
PFL: PFL_4199(atuF)
PPRC: PFLCHA0_c42620(accA3)
PPRO: PPC_4296(atuF)
PFS: PFLU_4397
PFC: PflA506_3701(atuF)
PFB: VO64_5139
PMAN: OU5_1500
PFW: PF1751_v1c38920(atuF)
PKC: PKB_3706(MCCC1)
PSEM: TO66_22075
PSOS: POS17_4287(atuF)
PANR: A7J50_4075
PSET: THL1_3723
PSIL: PMA3_07210
PALL: UYA_10245
POJ: PtoMrB4_17770(atuF)
PMAO: PMYSY11_2043(accA)
ACB: A1S_3005
ABM: ABSDF2868
ABY: ABAYE0483
ABN: AB57_3456
ABB: ABBFA_00512(accA1_1)
ABX: ABK1_3256
ABH: M3Q_3437
ABAD: ABD1_28940
ABAZ: P795_2380
ABAU: IX87_11720
ABAA: IX88_17965
ACC: BDGL_002469(mccC1)
AGU: AS4_37340(liuD)
PAT: Patl_0319
MAQ: Maqu_2807
MHC: MARHY2695
MAD: HP15_2542
MARJ: MARI_02960(accA1_1)
MICC: AUP74_02725(accA1_2)
MICT: FIU95_11180(accA2)
CYQ: Q91_1219
HCH: HCH_05752
ABO: ABO_0986(accA)
ADI: B5T_00491 B5T_01797(accA)
APAC: S7S_10305
RPI: Rpic_0108
REH: H16_A2142(accA2)
CNC: CNE_1c27010(accA4)
RME: Rmet_1724(accC)
BPS: BPSS2034
BPSE: BDL_5457
BPSM: BBQ_4087
BPSU: BBN_5509
BPSD: BBX_4624
BPK: BBK_4785
BPSH: DR55_5687
BPSA: BBU_3964
BPSO: X996_5492
BUT: X994_5049
BTQ: BTQ_3581
BTJ: BTJ_4617
BTZ: BTL_5404
BTD: BTI_4952
BTV: BTHA_4798
BTHE: BTN_5075
BTHM: BTRA_5343
BTHA: DR62_5204
BTHL: BG87_5411
BOK: DM82_6353
BOC: BG90_4321
BUL: BW21_4480
RFR: Rfer_2815
AAA: Acav_0072
ACRA: BSY15_2086
VEI: Veis_2415
CTES: O987_10855
LIH: L63ED372_00596(accA1_1)
HPSE: HPF_03625(accA1) HPF_12730(accA2)
RGE: RGE_32900
MXA: MXAN_0082(accC)
CCX: COCOR_03098(accC1)
BJA: blr0987(mccA)
BRA: BRADO6875
BBT: BBta_0676
BRS: S23_68190(mccA)
AOL: S58_06010
BRAD: BF49_7199
BARH: WN72_46665
BVZ: BRAD3257_8743(mccA)
BEL: BE61_03480(mccA)
RPA: RPA2144
RPB: RPB_3259
RPC: RPC_3200
RPD: RPD_2205
RPE: RPE_2255
RPT: Rpal_2436
RVA: Rvan_3447
RBM: TEF_16790
PSF: PSE_4597
SIL: SPO0579
LAQU: R2C4_13395
GAK: X907_0622
SECH: B18_27415
SFLA: SPHFLASMR4Y_02317(accA1)
RCE: RC1_3531
TMO: TMO_a0453
PBF: CFX0092_A2505(accA)
 » show all
Reference
  Authors
Forster-Fromme K, Hoschle B, Mack C, Bott M, Armbruster W, Jendrossek D
  Title
Identification of genes and proteins necessary for catabolism of acyclic terpenes and leucine/isovalerate in Pseudomonas aeruginosa.
  Journal
Appl Environ Microbiol 72:4819-28 (2006)
DOI:10.1128/AEM.00853-06
  Sequence
[pae:PA2891]

KEGG   ENZYME: 6.4.1.5
Entry
EC 6.4.1.5                  Enzyme                                 

Name
geranoyl-CoA carboxylase;
geranoyl coenzyme A carboxylase;
geranyl-CoA carboxylase
Class
Ligases;
Forming carbon-carbon bonds;
Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
Sysname
geranoyl-CoA:carbon-dioxide ligase (ADP-forming)
Reaction(IUBMB)
ATP + geranoyl-CoA + HCO3- = ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA [RN:R03494]
Reaction(KEGG)
R03494
Substrate
ATP [CPD:C00002];
geranoyl-CoA [CPD:C01920];
HCO3- [CPD:C00288]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA [CPD:C01291]
Comment
A biotinyl-protein. Also carboxylates dimethylpropenoyl-CoA and farnesoyl-CoA.
History
EC 6.4.1.5 created 1972
Pathway
ec00281  Geraniol degradation
ec01110  Biosynthesis of secondary metabolites
Orthology
K13777  geranyl-CoA carboxylase alpha subunit
K13778  geranyl-CoA carboxylase beta subunit
Genes
RGL: CS053_05360 CS053_05370
DJI: CH75_09960 CH75_09970
PAE: PA2888(atuC) PA2891(atuF)
PAEV: N297_2991 N297_2994
PAEI: N296_2991 N296_2994
PAU: PA14_26670 PA14_26720(mccB)
PAP: PSPA7_2263 PSPA7_2266
PAG: PLES_21731(atuF) PLES_21761(atuC)
PAF: PAM18_2072(atuF) PAM18_2075(atuC)
PNC: NCGM2_3999(mccB) NCGM2_4002
PAEU: BN889_03226(atuC) BN889_03229(atuF)
PCQ: PcP3B5_19970(accA1_1) PcP3B5_20000
PFL: PFL_4196(atuC) PFL_4199(atuF)
PPRC: PFLCHA0_c42590(yngE2) PFLCHA0_c42620(accA3)
PPRO: PPC_4293(atuC) PPC_4296(atuF)
PFC: PflA506_3698(atuC) PflA506_3701(atuF)
PKC: PKB_3703(l(2)04524) PKB_3706(MCCC1)
PSOS: POS17_4284(atuC) POS17_4287(atuF)
POJ: PtoMrB4_17770(atuF) PtoMrB4_17800(atuC)
ABB: ABBFA_00509(accD5) ABBFA_00512(accA1_1)
AGU: AS4_37340(liuD) AS4_37370(accD)
MARJ: MARI_02960(accA1_1) MARI_02990(pccB)
SAGA: M5M_01905
MICC: AUP74_02722 AUP74_02725(accA1_2)
MICT: FIU95_11165 FIU95_11180(accA2)
CYQ: Q91_1219 Q91_1221(accB1)
ABO: ABO_0986(accA) ABO_0989(accD)
REH: H16_A2142(accA2) H16_A2144(pccB)
CNC: CNE_1c27010(accA4) CNE_1c27040(pccB)
RME: Rmet_1721(pccB) Rmet_1724(accC)
HPSE: HPF_03610 HPF_03625(accA1) HPF_12725 HPF_12730(accA2)
MXA: MXAN_0081(accB) MXAN_0082(accC)
CCX: COCOR_03097(accB) COCOR_03098(accC1)
BJA: blr0986(mccB) blr0987(mccA)
BRS: S23_68190(mccA) S23_68200(mccB)
BEL: BE61_03480(mccA) BE61_03490(mccB)
PBF: CFX0092_A2505(accA)
 » show all
Reference
1  [PMID:14087299]
  Authors
SEUBERT W, FASS E, REMBERGER U.
  Title
[STUDIES ON THE BACTERIAL DEGRADATION OF ISOPRENOID COMPOUNDS. III. PURIFICATION AND PROPERTIES OF GERANYL CARBOXYLASE.]
  Journal
Biochem Z 338:265-75 (1963)
Other DBs
ExplorEnz - The Enzyme Database: 6.4.1.5
IUBMB Enzyme Nomenclature: 6.4.1.5
ExPASy - ENZYME nomenclature database: 6.4.1.5
UM-BBD (Biocatalysis/Biodegradation Database): 6.4.1.5
BRENDA, the Enzyme Database: 6.4.1.5
CAS: 37324-35-9

KEGG   REACTION: R03494
Entry
R03494                      Reaction                               

Name
geranoyl-CoA:carbon-dioxide ligase (ADP-forming)
Definition
ATP + Geranoyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA
Equation
Reaction class
RC00002  C00002_C00008
RC00367  C00288_C01291
RC00942  C01291_C01920
Enzyme
Pathway
rn00281  Geraniol degradation
rn01110  Biosynthesis of secondary metabolites
Orthology
K13777  geranyl-CoA carboxylase alpha subunit [EC:6.4.1.5]
K13778  geranyl-CoA carboxylase beta subunit [EC:6.4.1.5]
Other DBs
RHEA: 17704

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