KEGG   ORTHOLOGY: K14077
Entry
K14077                      KO                                     

Symbol
TPCN2
Name
two pore calcium channel protein 2
Pathway
map04020  Calcium signaling pathway
map04972  Pancreatic secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K14077  TPCN2; two pore calcium channel protein 2
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    K14077  TPCN2; two pore calcium channel protein 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K14077  TPCN2; two pore calcium channel protein 2
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, two-pore (TPC)
   K14077  TPCN2; two pore calcium channel protein 2
Other DBs
GO: 0005245 0072345
TC: 1.A.1.11.19
Genes
HSA: 219931(TPCN2)
PTR: 747605(TPCN2)
PPS: 100971084(TPCN2)
GGO: 101128404(TPCN2)
PON: 100444397(TPCN2)
NLE: 100590340(TPCN2)
MCC: 709391(TPCN2)
MCF: 102137514(TPCN2)
CSAB: 103247263(TPCN2)
CATY: 105577613(TPCN2)
PANU: 101024157(TPCN2)
RRO: 104658393(TPCN2)
RBB: 108538678(TPCN2)
TFN: 117081719(TPCN2)
PTEH: 111522278(TPCN2)
CJC: 100404812(TPCN2)
SBQ: 101043722(TPCN2)
MMUR: 105867514(TPCN2)
MMU: 233979(Tpcn2)
MCAL: 110298277(Tpcn2)
MPAH: 110325664(Tpcn2)
RNO: 309139(Tpcn2)
MCOC: 116103286(Tpcn2)
MUN: 110546949(Tpcn2)
CGE: 100755221(Tpcn2)
PLEU: 114694507(Tpcn2)
NGI: 103751497(Tpcn2)
HGL: 101712986(Tpcn2)
CCAN: 109696028(Tpcn2)
TUP: 102491632(TPCN2)
CFA: 483683(TPCN2)
VVP: 112924016(TPCN2)
VLG: 121471316(TPCN2)
AML: 100473327(TPCN2)
UMR: 103671141(TPCN2)
UAH: 113243987(TPCN2)
ORO: 101371838(TPCN2)
MPUF: 101690957(TPCN2)
EJU: 114220216(TPCN2)
MLX: 118016161(TPCN2)
FCA: 101086345(TPCN2)
PTG: 102966890(TPCN2)
PPAD: 109246891(TPCN2)
AJU: 106971083(TPCN2)
HHV: 120233904(TPCN2)
BTA: 516679(TPCN2)
BOM: 102270254(TPCN2)
BIU: 109554580(TPCN2)
BBUB: 102398080(TPCN2)
CHX: 102189285(TPCN2)
OAS: 101115493(TPCN2)
ODA: 120874141(TPCN2)
SSC: 100523421(TPCN2)
CFR: 102521432(TPCN2)
CBAI: 105070366(TPCN2)
CDK: 105104394(TPCN2)
BACU: 103012938(TPCN2)
LVE: 103090869(TPCN2)
OOR: 101273036(TPCN2)
DLE: 111183635(TPCN2)
PCAD: 102973335(TPCN2)
ECB: 102150167(TPCN2)
EPZ: 103551288(TPCN2)
EAI: 106844263(TPCN2)
MYB: 102249015(TPCN2)
MYD: 102758401(TPCN2)
MMYO: 118665186(TPCN2)
MNA: 107537413(TPCN2)
HAI: 109389312(TPCN2)
DRO: 112317329(TPCN2)
SHON: 118998395(TPCN2)
AJM: 119041892(TPCN2)
MMF: 118629013(TPCN2)
PALE: 102893492(TPCN2)
PGIG: 120584637(TPCN2)
RAY: 107503410(TPCN2)
MJV: 108385313(TPCN2)
TOD: 119248801(TPCN2)
LAV: 100664499(TPCN2)
TMU: 101354284
SHR: 100921551(TPCN2)
PCW: 110197117(TPCN2)
OAA: 100074753(TPCN2)
GGA: 423141(TPCN2)
PCOC: 116229083(TPCN2)
MGP: 100539606(TPCN2)
CJO: 107314443(TPCN2)
NMEL: 110401008(TPCN2)
APLA: 101790097(TPCN2)
ACYG: 106040885(TPCN2)
TGU: 100227742(TPCN2)
LSR: 110469636(TPCN2)
SCAN: 103822111(TPCN2)
PMOA: 120509869(TPCN2)
GFR: 102033680(TPCN2)
FAB: 101808920(TPCN2)
PHI: 102099845(TPCN2)
PMAJ: 107206173(TPCN2)
CCAE: 111930660(TPCN2)
CCW: 104697602(TPCN2)
ETL: 114070760
FPG: 101918177(TPCN2)
FCH: 102055799(TPCN2)
CLV: 102096153(TPCN2)
EGZ: 104124711(TPCN2)
NNI: 104009494(TPCN2)
ACUN: 113481248(TPCN2)
PADL: 103925818(TPCN2)
AAM: 106498309(TPCN2)
ASN: 102384386(TPCN2)
AMJ: 102570546(TPCN2)
CPOO: 109321101(TPCN2)
GGN: 109299001(TPCN2)
PSS: 102447456(TPCN2)
CMY: 102937752(TPCN2)
CPIC: 101943237(TPCN2)
TST: 117877046(TPCN2)
CABI: 116819290(TPCN2)
ACS: 100565414(tpcn2)
PVT: 110073509(TPCN2)
PBI: 103057589
PMUR: 107294551(TPCN2)
TSR: 106538208
PGUT: 117665430(TPCN2)
PMUA: 114583952(TPCN2) 114596932
ZVI: 118085963(TPCN2)
GJA: 107121503(TPCN2)
XLA: 734733(tpcn2.L)
XTR: 100492057(tpcn2)
NPR: 108785440(TPCN2)
DRE: 777614(tpcn2)
IPU: 108271175(tpcn2)
PHYP: 113536479(tpcn2)
AMEX: 103032998(tpcn2)
EEE: 113578608(tpcn2)
LCO: 104934214(tpcn2)
CGOB: 115024761(tpcn2)
ELY: 117259807(tpcn2)
PLEP: 121943270(tpcn2)
SLUC: 116045203(tpcn2)
ECRA: 117942349(tpcn2)
PFLV: 114559536(tpcn2)
GAT: 120835166(tpcn2)
MSAM: 119890017(tpcn2)
CUD: 121507300(tpcn2)
MZE: 101486560(tpcn2)
ONL: 100695350(tpcn2)
OAU: 116319090(tpcn2)
OLA: 101161121(tpcn2)
OML: 112152886(tpcn2)
XMA: 102225571(tpcn2)
XCO: 114143100(tpcn2)
XHE: 116719081(tpcn2)
PRET: 103462325(tpcn2)
CVG: 107103421(tpcn2)
CTUL: 119772684(tpcn2)
NFU: 107372374(tpcn2) 107372664
KMR: 108237840(tpcn2)
ALIM: 106512949(tpcn2)
AOCE: 111585663(tpcn2)
CSEM: 103379193(tpcn2)
POV: 109624734(tpcn2)
LCF: 108880509(tpcn2)
SDU: 111220931(tpcn2)
SLAL: 111669285(tpcn2)
XGL: 120790028(tpcn2)
HCQ: 109521790(tpcn2)
BPEC: 110158817(tpcn2)
MALB: 109967848(tpcn2)
SASA: 106562052(tpcn2) 106587138
OMY: 110506399(tpcn2) 110526229
ELS: 105018291 109614579(tpcn2)
SFM: 108941258(tpcn2)
PKI: 111848057(tpcn2) 111851957
AANG: 118227181(tpcn2)
LOC: 102689358(tpcn2)
ARUT: 117432197(tpcn2) 117434461
LCM: 102361800(TPCN2)
CMK: 103175101(tpcn2)
RTP: 109918250(tpcn2)
BFO: 118406642
BBEL: 109476508
CIN: 100176107
SCLV: 120338976
SPU: 115917870 592190(TPC2)
APLC: 110991028
PCAN: 112565867
BGT: 106066282
GAE: 121372677
CRG: 105332264
MYI: 110460652
PMAX: 117327602
OBI: 106880089
LAK: 106173848
EGL: EGR_03595
NVE: 5506091
EPA: 110240286
ATEN: 116302445
AMIL: 114962516
PDAM: 113677245
DGT: 114520810
HMG: 101236940
AQU: 105314080
 » show all
Reference
  Authors
Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, Parrington J, Galione A
  Title
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.
  Journal
Curr Biol 20:703-9 (2010)
DOI:10.1016/j.cub.2010.02.049
Reference
  Authors
Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, Wyatt CN, Parrington J, Ma J, Evans AM, Galione A, Zhu MX
  Title
NAADP mobilizes calcium from acidic organelles through two-pore channels.
  Journal
Nature 459:596-600 (2009)
DOI:10.1038/nature08030
  Sequence
[hsa:219931]

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