KEGG   ORTHOLOGY: K14085
Entry
K14085                      KO                                     

Symbol
ALDH7A1
Name
aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Pathway
map00010  Glycolysis / Gluconeogenesis
map00053  Ascorbate and aldarate metabolism
map00071  Fatty acid degradation
map00260  Glycine, serine and threonine metabolism
map00280  Valine, leucine and isoleucine degradation
map00310  Lysine degradation
map00330  Arginine and proline metabolism
map00340  Histidine metabolism
map00380  Tryptophan metabolism
map00410  beta-Alanine metabolism
map00561  Glycerolipid metabolism
map00620  Pyruvate metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map04936  Alcoholic liver disease
Module
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00135  GABA biosynthesis, eukaryotes, putrescine => GABA
M00555  Betaine biosynthesis, choline => betaine
Disease
H01247  Pyridoxine-dependent epilepsy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00053 Ascorbate and aldarate metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00620 Pyruvate metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00561 Glycerolipid metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00280 Valine, leucine and isoleucine degradation
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00310 Lysine degradation
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00330 Arginine and proline metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00340 Histidine metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
   00380 Tryptophan metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.3  aldehyde dehydrogenase (NAD+)
     K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
    1.2.1.8  betaine-aldehyde dehydrogenase
     K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
    1.2.1.31  L-aminoadipate-semialdehyde dehydrogenase
     K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1
Other DBs
RN: R00631 R00710 R00904 R01752 R01986 R02549 R02565 R02566 R02678 R02940 R02957 R03102 R03103 R03283 R03869 R04065 R04506 R04903 R05050
GO: 0004043 0008802 0004029
Genes
HSA: 501(ALDH7A1)
PTR: 462033(ALDH7A1)
PPS: 100970731(ALDH7A1)
GGO: 101148545(ALDH7A1)
PON: 100461726(ALDH7A1)
NLE: 100583462(ALDH7A1)
MCC: 702749(ALDH7A1)
MCF: 102120771(ALDH7A1)
CSAB: 103245164(ALDH7A1)
CATY: 105599693(ALDH7A1)
PANU: 101019039(ALDH7A1)
RRO: 104677423(ALDH7A1)
RBB: 108537700(ALDH7A1)
TFN: 117065947(ALDH7A1) 117083919
PTEH: 111529996(ALDH7A1)
CJC: 100401828(ALDH7A1) 100410565(ALDH7A1)
SBQ: 101045920(ALDH7A1)
MMUR: 105854886(ALDH7A1)
MMU: 110695(Aldh7a1)
MCAL: 110285158(Aldh7a1)
MPAH: 110333007(Aldh7a1)
RNO: 291450(Aldh7a1)
MCOC: 116087179(Aldh7a1)
MUN: 110562122(Aldh7a1)
CGE: 100756509(Aldh7a1)
PLEU: 114706088(Aldh7a1)
NGI: 103740420(Aldh7a1)
HGL: 101711696(Aldh7a1)
CCAN: 109699996(Aldh7a1)
OCU: 100344302(ALDH7A1)
OPI: 101518224(ALDH7A1)
TUP: 102495542(ALDH7A1)
CFA: 481486(ALDH7A1)
VVP: 112917127(ALDH7A1)
VLG: 121494986(ALDH7A1)
AML: 100475712(ALDH7A1)
UMR: 103670577(ALDH7A1)
UAH: 113261663(ALDH7A1)
ORO: 101372739(ALDH7A1)
ELK: 111148305
MPUF: 101679297(ALDH7A1)
EJU: 114209580(ALDH7A1)
MLX: 118016584(ALDH7A1)
FCA: 101086623(ALDH7A1)
PYU: 121010631(ALDH7A1)
PBG: 122486911(ALDH7A1)
PTG: 102951788(ALDH7A1)
PPAD: 109250945(ALDH7A1)
AJU: 106970741(ALDH7A1)
HHV: 120234735(ALDH7A1)
BTA: 507477(ALDH7A1)
BOM: 102285292(ALDH7A1)
BIU: 109561847(ALDH7A1)
BBUB: 102391870(ALDH7A1)
CHX: 102187125(ALDH7A1)
OAS: 101108127(ALDH7A1)
ODA: 120864703(ALDH7A1)
CCAD: 122423739 122440104(ALDH7A1)
SSC: 106504110(ALDH7A1)
CFR: 102512958(ALDH7A1)
CBAI: 105082073(ALDH7A1)
CDK: 105089785(ALDH7A1)
BACU: 103018812 103019170(ALDH7A1)
LVE: 103087111(ALDH7A1)
OOR: 101279003(ALDH7A1)
DLE: 111182376(ALDH7A1)
PCAD: 102990841(ALDH7A1)
ECB: 100063766(ALDH7A1)
EPZ: 103557440(ALDH7A1)
EAI: 106842819(ALDH7A1)
MYB: 102247575(ALDH7A1)
MYD: 102754535(ALDH7A1)
MMYO: 118656151(ALDH7A1)
MNA: 107540928(ALDH7A1)
PKL: 118702745(ALDH7A1)
HAI: 109379078(ALDH7A1)
DRO: 112314805(ALDH7A1)
SHON: 118974985(ALDH7A1)
AJM: 119044019(ALDH7A1)
MMF: 118641824(ALDH7A1)
PALE: 102880590(ALDH7A1)
PGIG: 120590904(ALDH7A1)
RAY: 107498603(ALDH7A1)
MJV: 108401917(ALDH7A1)
TOD: 119243529(ALDH7A1)
LAV: 100656260(ALDH7A1)
TMU: 101361542
MDO: 100009965(ALDH7A1)
SHR: 100930576(ALDH7A1)
PCW: 110223911(ALDH7A1)
OAA: 100074256(ALDH7A1)
GGA: 426812(ALDH7A1)
PCOC: 116226072(ALDH7A1)
MGP: 104915364(ALDH7A1)
CJO: 107306701(ALDH7A1)
NMEL: 110389971(ALDH7A1)
APLA: 101793275(ALDH7A1)
ACYG: 106046528(ALDH7A1)
TGU: 100223716(ALDH7A1)
LSR: 110467766(ALDH7A1)
SCAN: 103821480(ALDH7A1)
PMOA: 120513570(ALDH7A1)
OTC: 121332722(ALDH7A1)
PRUF: 121362563(ALDH7A1)
GFR: 102042249(ALDH7A1)
FAB: 101806923(ALDH7A1)
PHI: 102106824(ALDH7A1)
PMAJ: 107198296(ALDH7A1)
CCAE: 111941214(ALDH7A1)
CCW: 104690506(ALDH7A1)
ETL: 114069037(ALDH7A1)
FPG: 101917601(ALDH7A1)
FCH: 102052577(ALDH7A1)
CLV: 102091436(ALDH7A1)
EGZ: 104124248(ALDH7A1)
NNI: 104016339(ALDH7A1)
ACUN: 113489748(ALDH7A1)
PADL: 103914477(ALDH7A1)
AROW: 112961617(ALDH7A1)
NPD: 112953492(ALDH7A1)
DNE: 112992375(ALDH7A1)
ASN: 102368427(ALDH7A1)
AMJ: 102563610(ALDH7A1)
CPOO: 109323589(ALDH7A1)
GGN: 109297204(ALDH7A1)
PSS: 102458471(ALDH7A1)
CMY: 102940167(ALDH7A1)
CPIC: 101937973(ALDH7A1)
TST: 117878720(ALDH7A1)
CABI: 116835602(ALDH7A1)
ACS: 100560663(aldh7a1)
PVT: 110077534(ALDH7A1)
PBI: 103049565(ALDH7A1)
PMUR: 107283290(ALDH7A1)
TSR: 106537542(ALDH7A1)
PGUT: 117661316(ALDH7A1)
ZVI: 118076849(ALDH7A1)
GJA: 107112391(ALDH7A1)
XLA: 108707197(aldh7a1.S) 447522(aldh7a1.L)
XTR: 549131(aldh7a1)
NPR: 108799792(ALDH7A1)
DRE: 334197(aldh7a1)
SRX: 107715563(aldh7a1)
SANH: 107657454(aldh7a1)
SGH: 107573911(aldh7a1)
CCAR: 109097311(aldh7a1)
CAUA: 113109506(aldh7a1)
IPU: 108277325(aldh7a1)
PHYP: 113543635(aldh7a1)
AMEX: 103034062(aldh7a1)
EEE: 113589019(aldh7a1)
TRU: 101066288(aldh7a1)
LCO: 104931924(aldh7a1)
NCC: 104947674(aldh7a1)
CGOB: 115006729(aldh7a1)
ELY: 117253877(aldh7a1)
PLEP: 121966268(aldh7a1)
SLUC: 116055256(aldh7a1)
ECRA: 117950645(aldh7a1)
PFLV: 114561474(aldh7a1)
GAT: 120823954(aldh7a1)
PPUG: 119216332(aldh7a1)
MSAM: 119900653(aldh7a1)
CUD: 121512782(aldh7a1)
MZE: 101482988(aldh7a1)
ONL: 100699093(aldh7a1)
OAU: 116324600(aldh7a1)
OLA: 101157525(aldh7a1)
OML: 112150430(aldh7a1)
XMA: 102233064(aldh7a1)
XCO: 114150635(aldh7a1)
XHE: 116726093(aldh7a1)
PRET: 103464136(aldh7a1)
CVG: 107103171(aldh7a1)
CTUL: 119774637(aldh7a1)
NFU: 107392683(aldh7a1)
KMR: 108230647(aldh7a1)
ALIM: 106511506(aldh7a1)
AOCE: 111565984(aldh7a1)
CSEM: 103393055(aldh7a1)
POV: 109625620(aldh7a1)
LCF: 108881294(aldh7a1)
SDU: 111217230(aldh7a1)
SLAL: 111650170(aldh7a1)
XGL: 120790806(aldh7a1)
HCQ: 109522068(aldh7a1)
BPEC: 110160079(aldh7a1)
MALB: 109958202(aldh7a1)
SASA: 100194754(aldh7a1)
OTW: 112220006(aldh7a1)
OMY: 110523197(aldh7a1)
SALP: 111961923(aldh7a1)
SNH: 120025785(aldh7a1)
ELS: 105021749(aldh7a1)
SFM: 108929860(aldh7a1)
PKI: 111861025(aldh7a1)
AANG: 118212077(aldh7a1)
LOC: 102696035(aldh7a1)
PSPA: 121302406(aldh7a1) 121315548
LCM: 102356888(ALDH7A1)
CMK: 103182361(aldh7a1)
RTP: 109914520(aldh7a1)
BFO: 118409632
BBEL: 109476845
CIN: 100184485
SCLV: 120348317
SPU: 588376
APLC: 110981183
SKO: 100370075
DME: Dmel_CG9629(Aldh7A1)
DER: 6543557
DSE: 6618402
DSI: Dsimw501_GD12292(Dsim_GD12292)
DAN: 6493640
DSR: 110190220
DPE: 6602384
DMN: 108151959
DWI: 6643070
DGR: 6558232
DNV: 108651977
DHE: 111604532
DVI: 6622382
CCAT: 101451143
BOD: 106620466
MDE: 101888197
SCAC: 106092395
LCQ: 111687514
ACOZ: 120959177
AARA: 120905741
AALB: 109412183
CPII: 120429236
AME: 411140
ACER: 107999134
BIM: 100747121
BBIF: 117204862
BVK: 117232657
BVAN: 117163584
BTER: 100648169
CCAL: 108627760
OBB: 114876201
MGEN: 117223838
NMEA: 116425255
CGIG: 122402952
MPHA: 105833498
AEC: 105151044
ACEP: 105619807
PBAR: 105422187
VEM: 105566549
HST: 105181543
DQU: 106746805
CFO: 105258160
FEX: 115244619
LHU: 105668398
PGC: 109862314
OBO: 105285166
PCF: 106790004
PFUC: 122519710
NVI: 100499205
CSOL: 105366902
MDL: 103568681
FAS: 105269842
DAM: 107037433
CCIN: 107268765
TCA: 658395
ATD: 109609044
AGB: 108903200
LDC: 111518171
NVL: 108564650
APLN: 108734302
PPYR: 116163050
OTU: 111413628
BMOR: 101735616
BMAN: 114249252
BANY: 112052143
PPOT: 106109424
PXU: 106127152
PRAP: 110996914
ZCE: 119835078
HAW: 110372538
TNL: 113491734
API: 100159019
DNX: 107173527
AGS: 114122915
RMD: 113550006
BTAB: 109031859
DCI: 103507305
CLEC: 106664902
HHAL: 106687723
NLU: 111050583
FOC: 113204404
ZNE: 110841255
CSEC: 111871798
FCD: 110857963
DMK: 116923820
PVM: 113805908
HAME: 121880028
HAZT: 108673773
EAF: 111717863
DSV: 119446853
RSAN: 119389294
RMP: 119184540
VDE: 111248475
VJA: 111266963
TUT: 107369629
DPTE: 113798509
PTEP: 107453898
SDM: 118184817
CEL: CELE_F01F1.6(alh-9)
CBR: CBG09070(Cbr-alh-9)
PCAN: 112553791
BGT: 106079896
GAE: 121383301
CRG: 105327683
MYI: 110455019
PMAX: 117333852
OBI: 106871909
OSN: 115218057
NVE: 5502556
EPA: 110236278
ATEN: 116299278
ADF: 107348248
AMIL: 114950886
PDAM: 113675597
SPIS: 111337300
HMG: 100198995(aldh7a1)
ATH: AT1G54100(ALDH7B4)
ALY: 9327851
CRB: 17897673
BRP: 103832634
THJ: 104815620
CPAP: 110818468
CIT: 102620491
PVY: 116120273
TCC: 18596241
GRA: 105773235
GHI: 107900603
GAB: 108473666
EGR: 104450978
GMX: 100811186(ALDH7B2) 547717(ALDH7B1)
VRA: 106762243
VAR: 108331606
VUN: 114163305
CCAJ: 109817465
APRC: 113866383
CAM: 101513733
LJA: Lj6g3v1177340.1(Lj6g3v1177340.1)
ADU: 107479115
AIP: 107630450
LANG: 109326919
FVE: 101298824
RCN: 112187805
PPER: 18770979
PMUM: 103340601
PAVI: 110749149
PDUL: 117634377
MDM: 103400922(MF-60) 103406954
ZJU: 107423905
MNT: 21410030
CSV: 101205436
CMO: 103500684
BHJ: 120086160
MCHA: 111021324
CMAX: 111488616
CMOS: 111455986
CPEP: 111807264
JCU: 105631377
JRE: 109009030
QSU: 111996661
QLO: 115968409
TWL: 119984486
SLY: 101252968
SPEN: 107014931
SOT: 102598345
CANN: 107861672
NSY: 104236891
NTO: 104107938
NAU: 109212832
INI: 109176332 109187725 109192542(PnG13-12)
SIND: 105157813
OEU: 111402278
HAN: 110886479
ECAD: 122595135
LSV: 111910340
CCAV: 112516483
DCR: 108228021
CSIN: 114307188
BVG: 104899742
SOE: 110804032
NNU: 104600531
MING: 122090163
NCOL: 116258957
OSA: 4347172
DOSA: Os09t0440300-01(Os09g0440300)
OBR: 102721194
BDI: 100831288
ATS: 109774117
SBI: 8080995
ZMA: 100282748
SITA: 101759802
PHAI: 112879547
PDA: 103709342
EGU: 105042090
MUS: 103995197
DCT: 110096635
PEQ: 110026035
AOF: 109845011
ATR: 18439499
PPP: 112278756
CNE: CNA07130
CNB: CNBA6940
TASA: A1Q1_08027
ABP: AGABI1DRAFT114711(AGABI1DRAFT_114711)
ABV: AGABI2DRAFT194900(AGABI2DRAFT_194900)
DFA: DFA_02437
SPAR: SPRG_06143
 » show all
Reference
  Authors
Brocker C, Lassen N, Estey T, Pappa A, Cantore M, Orlova VV, Chavakis T, Kavanagh KL, Oppermann U, Vasiliou V
  Title
Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress.
  Journal
J Biol Chem 285:18452-63 (2010)
DOI:10.1074/jbc.M109.077925
  Sequence
[hsa:501]

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