KEGG   ORTHOLOGY: K15095
Entry
K15095                      KO                                     

Name
E1.1.1.208
Definition
(+)-neomenthol dehydrogenase [EC:1.1.1.208]
Pathway
ko00902  Monoterpenoid biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00902 Monoterpenoid biosynthesis
    K15095  E1.1.1.208; (+)-neomenthol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.208  (+)-neomenthol dehydrogenase
     K15095  E1.1.1.208; (+)-neomenthol dehydrogenase
Other DBs
RN: R02548
GO: 0047501
Genes
LAK: 106157857
ATH: AT2G24190(SDR2) AT3G61220(SDR1)
ALY: 9314440 9314798
CRB: 17888559
CSAT: 104713863
EUS: EUTSA_v10006127mg
BRP: 103841948 103862836
BNA: 106370838 106411616 106416137 106416155 106445008
BOE: 106307253
RSZ: 108849556 108849570 108862066 108862123
LJA: Lj0g3v0101689.1(Lj0g3v0101689.1) Lj0g3v0163199.1(Lj0g3v0163199.1) Lj0g3v0210429.1(Lj0g3v0210429.1) Lj1g3v2627460.1(Lj1g3v2627460.1) Lj1g3v2627460.2(Lj1g3v2627460.2)
CSV: 101222482
CMO: 103492462
MCHA: 111024064
CMAX: 111485494
CMOS: 111461314
CPEP: 111779651
DOSA: Os02t0640600-00(Os02g0640600) Os04t0531750-00(Os04g0531750) Os04t0531900-01(Os04g0531900) Os04t0532100-01(Os04g0532100) Os04t0532400-01(Os04g0532400) Os07t0685800-01(Os07g0685800)
DCT: 110108646
ATR: 18425213
 » show all
Reference
  Authors
Choi HW, Lee BG, Kim NH, Park Y, Lim CW, Song HK, Hwang BK
  Title
A role for a menthone reductase in resistance against microbial pathogens in plants.
  Journal
Plant Physiol 148:383-401 (2008)
DOI:10.1104/pp.108.119461
  Sequence
[cann:107839158]

KEGG   ENZYME: 1.1.1.208
Entry
EC 1.1.1.208                Enzyme                                 

Name
(+)-neomenthol dehydrogenase;
monoterpenoid dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(+)-neomenthol:NADP+ oxidoreductase
Reaction(IUBMB)
(+)-neomenthol + NADP+ = (-)-menthone + NADPH + H+ [RN:R02548]
Reaction(KEGG)
R02548
Substrate
(+)-neomenthol [CPD:C00553];
NADP+ [CPD:C00006]
Product
(-)-menthone [CPD:C00843];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Not identical with EC 1.1.1.207 (-)-menthol dehydrogenase. Acts also on a number of other cyclohexanols and cyclohexenols.
History
EC 1.1.1.208 created 1984
Pathway
ec00902  Monoterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K15095  (+)-neomenthol dehydrogenase
Genes
LAK: 106157857
ATH: AT2G24190(SDR2) AT3G61220(SDR1)
ALY: 9314440 9314798
CRB: 17888559
CSAT: 104713863
EUS: EUTSA_v10006127mg
BRP: 103841948 103862836
BNA: 106370838 106411616 106416137 106416155 106445008
BOE: 106307253
RSZ: 108849556 108849570 108862066 108862123
LJA: Lj0g3v0101689.1(Lj0g3v0101689.1) Lj0g3v0163199.1(Lj0g3v0163199.1) Lj0g3v0210429.1(Lj0g3v0210429.1) Lj1g3v2627460.1(Lj1g3v2627460.1) Lj1g3v2627460.2(Lj1g3v2627460.2)
CSV: 101222482
CMO: 103492462
MCHA: 111024064
CMAX: 111485494
CMOS: 111461314
CPEP: 111779651
DOSA: Os02t0640600-00(Os02g0640600) Os04t0531750-00(Os04g0531750) Os04t0531900-01(Os04g0531900) Os04t0532100-01(Os04g0532100) Os04t0532400-01(Os04g0532400) Os07t0685800-01(Os07g0685800)
DCT: 110108646
ATR: 18425213
 » show all
Reference
1  [PMID:16662335]
  Authors
Kjonaas R, Martinkus-Taylor C, Croteau R.
  Title
Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves.
  Journal
Plant Physiol 69:1013-1017 (1982)
DOI:10.1104/pp.69.5.1013
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.208
IUBMB Enzyme Nomenclature: 1.1.1.208
ExPASy - ENZYME nomenclature database: 1.1.1.208
BRENDA, the Enzyme Database: 1.1.1.208
CAS: 81811-47-4

KEGG   REACTION: R02548
Entry
R02548                      Reaction                               

Name
(+)-neomenthol:NADP+ oxidoreductase
Definition
(+)-Neomenthol + NADP+ <=> (-)-Menthone + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00154  C00553_C00843
Enzyme
Pathway
rn00902  Monoterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K15095  (+)-neomenthol dehydrogenase [EC:1.1.1.208]
Other DBs
RHEA: 23815

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