KEGG   ORTHOLOGY: K15856
Entry
K15856                      KO                                     
Symbol
rmd
Name
GDP-4-dehydro-6-deoxy-D-mannose reductase [EC:1.1.1.281]
Pathway
map00051  Fructose and mannose metabolism
map00520  Amino sugar and nucleotide sugar metabolism
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K15856  rmd; GDP-4-dehydro-6-deoxy-D-mannose reductase
   00520 Amino sugar and nucleotide sugar metabolism
    K15856  rmd; GDP-4-dehydro-6-deoxy-D-mannose reductase
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K15856  rmd; GDP-4-dehydro-6-deoxy-D-mannose reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.281  GDP-4-dehydro-6-deoxy-D-mannose reductase
     K15856  rmd; GDP-4-dehydro-6-deoxy-D-mannose reductase
Other DBs
RN: R03397 R03399
COG: COG0451
GO: 0033705
Genes
YPB: YPTS_1054
YPQ: DJ40_1349
YPU: BZ21_253
YPR: BZ20_1036
YPC: BZ23_529
XAL: XALC_2707(rmd)
XVA: C7V42_18455
PDD: MNQ95_09680
LCP: LC55x_4380
LGU: LG3211_4185
LEZ: GLE_4243
LEM: LEN_0958
PAE: PA5454(rmd)
PAEV: N297_5642
PAEI: N296_5642
PAU: PA14_72000(rmd)
PAG: PLES_58491(rmd)
PAF: PAM18_5576(rmd)
PNC: NCGM2_6231(rmd)
PAEB: NCGM1900_6309(rmd)
PAEP: PA1S_29460
PAEM: U769_29965
PAEL: T223_29925
PAEU: BN889_06061(rmd)
PAEG: AI22_04525
PAEC: M802_5640
PAEO: M801_5507
PCQ: PcP3B5_01740(rmd)
PSYR: N018_21315
PFE: PSF113_5885(rmd)
PMAN: OU5_3478
PSES: PSCI_5345
PSEM: TO66_31495
PALL: UYA_23050
ASIP: AQUSIP_18140(rmd)
BMAL: DM55_1487
BMAE: DM78_2667
BMAQ: DM76_1465
BMAI: DM57_1072
BMAF: DM51_1938
BMAZ: BM44_1066
BMAB: BM45_2463
BPM: BURPS1710b_3293(wcbK)
BPSE: BDL_2648
BPSM: BBQ_512
BPSU: BBN_640
BPSD: BBX_1046
BPZ: BP1026B_I0513(wcbK)
BPK: BBK_2133
BPSH: DR55_1721
BPSA: BBU_2765
BPSO: X996_1361
BUT: X994_3359
BTHA: DR62_530
PLG: NCTC10937_04677(gmd_1)
PVAC: HC248_00496(rmd)
CFU: CFU_1116(rmd)
CARE: LT85_3694
NET: Neut_0156
MBAT: BN1208_0921(wcbK)
SLAC: SKTS_36170(rmd)
CJJ: CJJ81176_1426(wcbK)
CJS: CJS3_1519(wcbK)
CJER: H730_08150
CJQ: UC78_1367(rmd_2)
CJR: CJE1611(wcbK)
CCF: YSQ_01730
CLX: CLAN_0158
COJ: CORN_0312
GEM: GM21_3399
DWD: DSCW_50670(rfbB)
MXA: MXAN_5328(rmd)
CCX: COCOR_02240(rmd)
SUR: STAUR_6036(rmd)
PLA: Plav_3348
RPA: RPA3952
RPD: RPD_1646
RPE: RPE_4260
RPT: Rpal_4473
NHA: Nham_2781
VGO: GJW-30_1_00102(rmd)
AZC: AZC_0053
MET: M446_5188
RVA: Rvan_2460
MSC: BN69_2011
PLEO: OHA_1_01728(rmd)
HDI: HDIA_0149(rmd_1)
RSU: NHU_00140
HNE: HNE_0794
ZMN: Za10_0101
ZMI: ZCP4_0102
ZMC: A265_00102(rfbE)
ZMR: A254_00102(rfbE)
SECH: B18_08485
GOH: B932_0830
ACR: Acry_0507
AMV: ACMV_05820(rmd)
RAP: RHOA_5432
MAGQ: MGMAQ_1159
AFR: AFE_3291
ACU: Atc_0208
PSYO: PB01_03670
PLV: ERIC2_c02840(gmd)
PSWU: SY83_13105
PALO: E6C60_3795
RCH: RUM_03120
BPB: bpr_I0151(gmd1) bpr_I0396
BHU: bhn_I0589
STH: STH1372
AACX: DEACI_0201
MTU: Rv0112(gca)
MTV: RVBD_0112
MTC: MT0121
MRA: MRA_0118(gca)
MTUR: CFBS_0121(gca)
MTO: MTCTRI2_0115(gca)
MTD: UDA_0112(gca)
MTN: ERDMAN_0130(gca)
MTUB: MT7199_0114(gca)
MTUC: J113_00800
MTUE: J114_00620
MTUH: I917_00860
MTUL: TBHG_00112
MTUT: HKBT1_0121(gca)
MTUU: HKBT2_0121(gca)
MTQ: HKBS1_0121(gca)
MBO: BQ2027_MB0116(gca)
MBB: BCG_0145(gca)
MBT: JTY_0116(gca)
MBM: BCGMEX_0116(gca)
MBX: BCGT_3909
MAF: MAF_01130(gca)
MMIC: RN08_0130
MCE: MCAN_01151(gca)
MCQ: BN44_10135(gca)
MCV: BN43_10130(gca)
MCX: BN42_10151(gca)
MCZ: BN45_10128(gca)
MAIC: MAIC_46420(rmd)
MTS: MTES_0931
RXY: Rxyl_0568
AFO: Afer_0745
EYY: EGYY_07230(Gmd)
RTS: CE91St31_13150(gca)
NSH: GXM_02821
TRO: trd_0916
STI: Sthe_1123
PBF: CFX0092_A0151(rmd)
TTR: Tter_1710
TRA: Trad_2861
BVO: Pan97_02120(rmd)
TTF: THTE_3576
PLH: VT85_25320(rmd_3)
GES: VT84_32605(rmd_2)
FTJ: FTUN_0673
ULI: ETAA1_19690(rmd)
SACI: Sinac_0262
PBOR: BSF38_03321(rmd_3) BSF38_04700(rmd_4)
AGV: OJF2_00280(rmd_1)
LIL: LA_0235(rfbB)
LIE: LIF_A0204(rfbB)
LIC: LIC_10203(rmd)
LIS: LIL_10203(rfbB1)
LBF: LBF_3148
LST: LSS_04696
LKB: LPTSP3_g34060(rfbB_2)
ABAC: LuPra_05853(rmd)
TLI: Tlie_1236
FSC: FSU_2786(rmd)
GAU: GAU_1969
GBA: J421_3572
MPI: Mpet_1407
PIS: Pisl_1490
TNE: Tneu_0491
LOKI: Lokiarch_35700(rmd)
AG: AAS55712(rmd)
 » show all
Reference
  Authors
Kneidinger B, Graninger M, Adam G, Puchberger M, Kosma P, Zayni S, Messner P
  Title
Identification of two GDP-6-deoxy-D-lyxo-4-hexulose reductases synthesizing GDP-D-rhamnose in Aneurinibacillus thermoaerophilus L420-91T.
  Journal
J Biol Chem 276:5577-83 (2001)
DOI:10.1074/jbc.M010027200
  Sequence
Reference
  Authors
Maki M, Jarvinen N, Rabina J, Roos C, Maaheimo H, Renkonen R
  Title
Functional expression of Pseudomonas aeruginosa GDP-4-keto-6-deoxy-D-mannose reductase which synthesizes GDP-rhamnose.
  Journal
Eur J Biochem 269:593-601 (2002)
DOI:10.1046/j.0014-2956.2001.02688.x
  Sequence
[pae:PA5454]

KEGG   ENZYME: 1.1.1.281
Entry
EC 1.1.1.281                Enzyme                                 
Name
GDP-4-dehydro-6-deoxy-D-mannose reductase;
GDP-4-keto-6-deoxy-D-mannose reductase [ambiguous];
GDP-6-deoxy-D-lyxo-4-hexulose reductase;
Rmd;
GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming);
GDP-6-deoxy-alpha-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
GDP-alpha-D-rhamnose:NAD(P)+ 4-oxidoreductase
Reaction(IUBMB)
GDP-alpha-D-rhamnose + NAD(P)+ = GDP-4-dehydro-alpha-D-rhamnose + NAD(P)H + H+ [RN:R03397 R03399]
Reaction(KEGG)
R03397 R03399
Substrate
GDP-alpha-D-rhamnose [CPD:C03117];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
GDP-4-dehydro-alpha-D-rhamnose [CPD:C01222];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
This enzyme differs from EC 1.1.1.187, GDP-4-dehydro-D-rhamnose reductase, in that the only product formed is GDP-alpha-D-rhamnose. D-Rhamnose is a constituent of lipopolysaccharides of Gram-negative plant and human pathogenic bacteria.
History
EC 1.1.1.281 created 2004
Pathway
ec00051  Fructose and mannose metabolism
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K15856  GDP-4-dehydro-6-deoxy-D-mannose reductase
Genes
YPBYPTS_1054
YPQDJ40_1349
YPUBZ21_253
YPRBZ20_1036
YPCBZ23_529
XALXALC_2707(rmd)
XVAC7V42_18455
PDDMNQ95_09680
LCPLC55x_4380
LGULG3211_4185
LEZGLE_4243
LEMLEN_0958
LUEDCD74_08535
THESFHQ07_06210
TCNH9L16_07610
TBVH9L17_06870
PAEPA5454(rmd)
PAEVN297_5642
PAEIN296_5642
PAUPA14_72000(rmd)
PAPPSPA7_6244
PAGPLES_58491(rmd)
PAFPAM18_5576(rmd)
PNCNCGM2_6231(rmd)
PAEBNCGM1900_6309(rmd)
PDKPADK2_29015
PSGG655_28685
PRPM062_28735
PAEPPA1S_29460
PAERPA1R_gp3389
PAEMU769_29965
PAELT223_29925
PAESSCV20265_6187
PAEUBN889_06061(rmd)
PAEGAI22_04525
PAECM802_5640
PAEOM801_5507
PALCA0T30_02620
PCQPcP3B5_01740(rmd)
PMUIG4G71_02280
PPJRK21_03607
PSTPSPTO_1007
PSYRN018_21315
PSAVPSA3335_07955
PCIPCH70_01440
PAVLBKM03_05930
PCABJGS08_04655
PCOFPOR16_19790
PTREI9H09_04235
PFEPSF113_5885(rmd)
PFOPfl01_5681
PMANOU5_3478
PBAPSEBR_a5628
PPUUPputUW4_01530
PDRH681_00575
PCHEY04_29645
PCZPCL1606_00120
PCPJM49_00325
PSESPSCI_5345
PSEMTO66_31495
PKRAYO71_00205
PKEDLD99_28840
PALLUYA_23050
PGYAWU82_06540
PBZGN234_18540
PATAJWU58_00740
PZEHU754_000880
PTZHU718_000865
PHVHU739_017845
PASGKSS96_21040
PAZEKSS91_08605
PIEHU724_000850
PGFJ0G10_00830
ACXAchr_26730
ASIPAQUSIP_18140(rmd)
MMOBF6R98_01275
HTREPV75_08920
APRSBI364_12375
MMEMarme_2111
BSANCHH28_01970
EPSL0Y14_14445
AQLBXU06_15900
REUReut_A0719
BMLBMA10229_A1069
BMALDM55_1487
BMAEDM78_2667
BMAQDM76_1465
BMAIDM57_1072
BMAFDM51_1938
BMAZBM44_1066
BMABBM45_2463
BPMBURPS1710b_3293(wcbK)
BPDBURPS668_3244
BPRGBP346_A3422
BPSEBDL_2648
BPSMBBQ_512
BPSUBBN_640
BPSDBBX_1046
BPZBP1026B_I0513(wcbK)
BPQBPC006_I3327
BPKBBK_2133
BPSHDR55_1721
BPSABBU_2765
BPSOX996_1361
BUTX994_3359
BTHADR62_530
BSTLBBJ41_08345
PLGNCTC10937_04677(gmd_1)
PVACHC248_00496(rmd)
VPEVarpa_0776
HHTF506_01240
CFUCFU_1116(rmd)
CARELT85_3694
CPRACPter91_3974
NETNeut_0156
DOEDENOEST_3345 DENOEST_3930(rmd)
MBATBN1208_0921(wcbK)
SLACSKTS_36170(rmd)
HWIA0Z60_06610
CJJCJJ81176_1426(wcbK)
CJNICDCCJ07001_1357
CJSCJS3_1519(wcbK)
CJERH730_08150
CJQUC78_1367(rmd_2)
CJRCJE1611(wcbK)
CJXBN867_14030
CLRUPTC16701_0315
CLMUPTC16712_0313
CLNUPTC3659_0325
CCFYSQ_01730
CAMRCAQ16704_0314
CSMCSUB8521_0326
CLXCLAN_0158
CAMZCVIC12175_0180
COJCORN_0312
CNVCNZW441b_0359
GEMGM21_3399
DOVDSCO28_03330
DWDDSCW_50670(rfbB)
MXAMXAN_5328(rmd)
MSDMYSTI_05892
MYMA176_001583
MFBMFUL124B02_31580
CCXCOCOR_02240(rmd)
MFULILAB_34470
MMASMYMAC_005188
SURSTAUR_6036(rmd)
RENEF513_04490
MOPMesop_2616
MAMMesau_05024
MERDEB233_24835
PHTBLM14_22615
PLAPlav_3348
RECRHECIAT_CH0000835
RLTRleg2_0410
RLBRLEG3_12110
RHNAMJ98_CH00792
RPHAAMC79_CH00800
RHXAMK02_CH00795
REZAMJ99_CH00792
RJGCCGE525_26930
RADCO657_02135
RIIFFM53_009075
RHIDFFM81_017170
RLNJ0663_12565
RBANJ2J98_03760
RLSHB780_25405
RFVRFYW14_04607
PDESFE840_018905
RPARPA3952
RPDRPD_1646
RPERPE_4260
RPTRpal_4473
RPXRpdx1_4326
NHANham_2781
VGOGJW-30_1_00102(rmd)
TRBHB776_03030
BOPAXW83_22490
AZCAZC_0053
MRDMrad2831_1050 Mrad2831_3464
METM446_5188
MORMOC_1268 MOC_3977
MPHYMCBMB27_00644 MCBMB27_00801 MCBMB27_02951
MEEDA075_19405
METDC0214_18365
METXA3862_14145 A3862_25325
METSDK389_04280
MMESMMSR116_25040 MMSR116_30875
MTADM6G65_05335 M6G65_05720
BBARRHAL1_00379
RVARvan_2460
MSCBN69_2011
MBRYB1812_17900
MROSEHO51_15185
MHEYH2LOC_014770
MPARF7D14_06745
MTWCQW49_16720
PLEOOHA_1_01728(rmd)
HDIHDIA_0149(rmd_1)
AALMLUX29_06815
AUBLXB15_15305
ACUTMRB58_13375
BSBBresu_3279
BRGA4249_12990
BDMEQG53_06295
BGOEIFJ75_18540
SITTM1040_1485
PHQD1820_14000
RSUNHU_00140
RHMB5V46_02120
PGVSL003B_2556
HNEHNE_0794
ZMNZa10_0101
ZMIZCP4_0102
ZMCA265_00102(rfbE)
ZMRA254_00102(rfbE)
ZMPZymop_1692
SECHB18_08485
GOXGOX1292 GOX1611
GOHB932_0830
GOYGLS_c13770 GLS_c17320
GALA0U94_14000
GTIFXF46_06825
GSPIGS75_09465
GFAMKW11_06770
GBEGbCGDNIH1_1716
GBHGbCGDNIH2_1716
GBCGbCGDNIH3_1716
GBSGbCGDNIH4_1716
ACRAcry_0507
AMVACMV_05820(rmd)
KBAA0U89_02310
RGIRGI145_01425
ROSCTJ15_19565
RMUCFOB66_18950
RMTIAI58_04410
LCKHN018_20315
RAPRHOA_5432
AOZHUE56_00500
SKTIGS68_03080
SMUCJL100_003195
SROEJL101_002965
MAGQMGMAQ_1159
AFRAFE_3291
AFELferr_2889
ACUAtc_0208
AFIAcife_1159 Acife_2355
AFJAFERRID_14960
AFPK1Y48_08195
LPAKGDS87_03105
PSYOPB01_03670
BBEBBR47_17540
BFMBP422_03945
BCHSJNE38_09525
PJDPjdr2_3512
PMSKNP414_03315 KNP414_06543
PMQPM3016_3535 PM3016_6150
PMWB2K_18235 B2K_31225
PLVERIC2_c02840(gmd)
PSONJI735_05780
PSWUSY83_13105
PCXLPB68_14475
PLUTEI981_25875
PPRTET464_03300
PALOE6C60_3795
PCELHUB94_07815
ANXACH33_01790
COHNKCTCHS21_54750 KCTCHS21_55810(rfbB)
CHEBHH215_19395
AFXJZ786_22515
AACOK1I37_06350
ACURJZ785_22290
CCLClocl_3957
RCHRUM_03120
BPBbpr_I0151(gmd1) bpr_I0396
BHUbhn_I0589
CLEClole_3815
CEWEKH84_00475
STHSTH1372
CALKHUE98_16880
DAIDesaci_4421
DEDDHBDCA_p1070
DECDCF50_p1140
DRUDesru_3675
AACXDEACI_0201
SAYTPY_1421 TPY_2530
SAPSulac_2236 Sulac_3283
MTURv0112(gca)
MTVRVBD_0112
MTCMT0121
MRAMRA_0118(gca)
MTFTBFG_10113
MTBTBMG_00113
MTKTBSG_00113
MTZTBXG_000113
MTIMRGA423_00730
MTECCDC5079_0098
MTURCFBS_0121(gca)
MTLCCDC5180_0098
MTOMTCTRI2_0115(gca)
MTDUDA_0112(gca)
MTNERDMAN_0130(gca)
MTJJ112_00620
MTUBMT7199_0114(gca)
MTUCJ113_00800
MTUEJ114_00620
MTXM943_00620
MTUHI917_00860
MTULTBHG_00112
MTUTHKBT1_0121(gca)
MTUUHKBT2_0121(gca)
MTQHKBS1_0121(gca)
MBOBQ2027_MB0116(gca)
MBBBCG_0145(gca)
MBTJTY_0116(gca)
MBMBCGMEX_0116(gca)
MBKK60_001250
MBXBCGT_3909
MAFMAF_01130(gca)
MMICRN08_0130
MCEMCAN_01151(gca)
MCQBN44_10135(gca)
MCVBN43_10130(gca)
MCXBN42_10151(gca)
MCZBN45_10128(gca)
MAICMAIC_46420(rmd)
MTSMTES_0931
MIHBJP65_06395 BJP65_14830
MWAE4K62_03120
PLKCIK06_06155
NABB1sIIB91_05480
ABAIIMCC26256_111953
RXYRxyl_0568
AFOAfer_0745
ATQGH723_12295
AQZKSP35_08645
IAMHC251_09120
EYYEGYY_07230(Gmd)
RTSCE91St31_13150(gca)
PMHP9215_14361
NSHGXM_02821
RRSRoseRS_1853 RoseRS_3655 RoseRS_4076
RCARcas_0917 Rcas_3281
CAUCaur_1970 Caur_2686
CHLChy400_2124 Chy400_2903
CAGCagg_0939 Cagg_2042
HAUHaur_3742 Haur_4820
TROtrd_0916
STISthe_1123
CAPCLDAP_16990
PBFCFX0092_A0151(rmd)
THUGKNN16_09480
TTRTter_1710
PMETG4Y79_14310
TRATrad_2861
VBAIMCC26134_03175
BVOPan97_02120(rmd)
TTFTHTE_3576
PLHVT85_25320(rmd_3)
GESVT84_32605(rmd_2)
GOGC1280_12470
GMSSOIL9_61690
TIMGMBLW1_14760
LRSPX52LOC_03147
FTJFTUN_0673
ULIETAA1_19690(rmd)
TSPHKIH39_19790
IPAIsop_0504 Isop_3611
SACISinac_0262
PBORBSF38_03321(rmd_3) BSF38_04700(rmd_4)
AGVOJF2_00280(rmd_1)
VAIBU251_02255
LILLA_0235(rfbB)
LIELIF_A0204(rfbB)
LICLIC_10203(rmd)
LISLIL_10203(rfbB1)
LBJLBJ_0170 LBJ_1162
LBLLBL_1216 LBL_2913
LBILEPBI_I3261
LBFLBF_3148
LSTLSS_04696
LAJA0128_01075
LMAYDPV73_04570
LKMEFP84_11920
LWLFHG68_01110 FHG68_08475
LKBLPTSP3_g34060(rfbB_2)
LNOMAL08_01050
ABACLuPra_05853(rmd)
FULC4N20_11210
LOTAXF11_05710
LSZJCM16776_1906 JCM16776_1907
ACOAmico_1359
TLITlie_1236
AMOAnamo_1479 Anamo_1883
FSUFisuc_2243
FSCFSU_2786(rmd)
GAUGAU_1969
GPHGEMMAAP_10230
GGRHKW67_04485
GBAJ421_3572
FEIK9M53_05440
FLPLK994_03645
MMABHQ865_06420
CAMUCA2015_3251
HYZAXW84_10635
HTBMTX78_04920
TMGUS01_C0001G0477
MIBUY43_C0001G0736
METBAW729_04020
MCHKMchiMG62_18220
MPIMpet_1407
HALYHYG82_08675
PISPisl_1490
TNETneu_0491
FLTSv326_1260
LOKILokiarch_35700(rmd)
AGWQT03_C0001G0689
 » show all
Reference
1  [PMID:11096116]
  Authors
Kneidinger B, Graninger M, Adam G, Puchberger M, Kosma P, Zayni S, Messner P
  Title
Identification of two GDP-6-deoxy-D-lyxo-4-hexulose reductases synthesizing GDP-D-rhamnose in Aneurinibacillus thermoaerophilus L420-91T.
  Journal
J Biol Chem 276:5577-83 (2001)
DOI:10.1074/jbc.M010027200
  Sequence
Reference
2  [PMID:11856318]
  Authors
Maki M, Jarvinen N, Rabina J, Roos C, Maaheimo H, Renkonen R
  Title
Functional expression of Pseudomonas aeruginosa GDP-4-keto-6-deoxy-D-mannose reductase which synthesizes GDP-rhamnose.
  Journal
Eur J Biochem 269:593-601 (2002)
DOI:10.1046/j.0014-2956.2001.02688.x
  Sequence
[pae:PA5454]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.281
IUBMB Enzyme Nomenclature: 1.1.1.281
ExPASy - ENZYME nomenclature database: 1.1.1.281
BRENDA, the Enzyme Database: 1.1.1.281

KEGG   REACTION: R03397
Entry
R03397                      Reaction                               
Name
GDP-6-deoxy-D-mannose:NAD+ 4-oxidoreductase
Definition
GDP-6-deoxy-D-mannose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+
Equation
Comment
NADP+ (see R03399)
Reaction class
RC00001  C00003_C00004
RC00182  C01222_C03117
Enzyme
1.1.1.187       1.1.1.281
Pathway
rn00051  Fructose and mannose metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Orthology
K15856  GDP-4-dehydro-6-deoxy-D-mannose reductase [EC:1.1.1.281]
Other DBs
RHEA: 13828

KEGG   REACTION: R03399
Entry
R03399                      Reaction                               
Name
GDP-6-deoxy-D-mannose:NADP+ 4-oxidoreductase
Definition
GDP-6-deoxy-D-mannose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+
Equation
Comment
NAD+ (see R03397)
Reaction class
RC00001  C00005_C00006
RC00182  C01222_C03117
Enzyme
1.1.1.187       1.1.1.281
Pathway
rn00051  Fructose and mannose metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Orthology
K15856  GDP-4-dehydro-6-deoxy-D-mannose reductase [EC:1.1.1.281]
Other DBs
RHEA: 13832

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