KEGG   ORTHOLOGY: K17751
Entry
K17751                      KO                                     
Symbol
MYH6_7
Name
myosin heavy chain 6/7
Pathway
map04022  cGMP-PKG signaling pathway
map04260  Cardiac muscle contraction
map04261  Adrenergic signaling in cardiomyocytes
map04919  Thyroid hormone signaling pathway
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05416  Viral myocarditis
Disease
H00292  Hypertrophic cardiomyopathy
H00294  Dilated cardiomyopathy
H00546  Atrial septal defect
H00594  Distal myopathy
H00656  Scapuloperoneal myopathy
H00703  Myosin storage myopathy
H00729  Sick sinus syndrome
H01216  Left ventricular noncompaction
H01977  Laing distal myopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K17751  MYH6_7; myosin heavy chain 6/7
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K17751  MYH6_7; myosin heavy chain 6/7
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K17751  MYH6_7; myosin heavy chain 6/7
   04261 Adrenergic signaling in cardiomyocytes
    K17751  MYH6_7; myosin heavy chain 6/7
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K17751  MYH6_7; myosin heavy chain 6/7
   05414 Dilated cardiomyopathy
    K17751  MYH6_7; myosin heavy chain 6/7
   05416 Viral myocarditis
    K17751  MYH6_7; myosin heavy chain 6/7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K17751  MYH6_7; myosin heavy chain 6/7
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K17751  MYH6_7; myosin heavy chain 6/7
Genes
HSA: 4624(MYH6) 4625(MYH7)
PTR: 452801(MYH6) 745215(MYH7)
PPS: 100978192(MYH6) 100978529
GGO: 101138909 101143194
PON: 100448481(MYH6) 100448828
NLE: 100599213 100601359
MCC: 100428939 713471(MYH6)
MCF: 102118251(MYH6) 102118628
CSAB: 103231478(MYH6) 103231480(MYH7)
CATY: 105598764(MYH7) 105598768(MYH6)
TGE: 112628433(MYH6) 112628434(MYH7)
RBB: 108523551 108523597(MYH6)
PTEH: 111554769
CJC: 100400067(MYH6) 100400430(MYH7)
SBQ: 101027633(MYH7) 101027939(MYH6)
OGA: 100956445
MMU: 140781(Myh7) 17888(Myh6)
MCAL: 110309088(Myh7) 110309092(Myh6)
MPAH: 110325261(Myh7) 110325318(Myh6)
RNO: 29556(Myh6) 29557(Myh7)
NGI: 103739453(Myh6) 103739454(Myh7)
HGL: 101707190(Myh7) 101707554(Myh6)
CCAN: 109697767(Myh6) 109697768(Myh7)
DORD: 105992465 105992471(Myh7)
OCU: 100125987(MYH6)
TUP: 102484562(MYH6) 102485681(MYH7)
CFA: 403807(MYH7)
AML: 100469933 100470185(MYH6)
UMR: 103681067(MYH6) 103681068
UAR: 123795772(MYH7) 123795774
ELK: 111158831
ORO: 101385604(MYH7) 101385904(MYH6)
EJU: 114217834 114217846(MYH7)
ZCA: 113909648
MLX: 118003495
FCA: 101095986(MYH6) 101096736
PYU: 121031370 121031521(MYH6)
PBG: 122468898(MYH6) 122468899
PTG: 102955104(MYH7)
AJU: 106979458
BTA: 100296004(MYH6) 282714(MYH7)
BOM: 102272267(MYH6) 102273976(MYH7)
BIU: 109564796
BBUB: 102401416(MYH6) 102413515
CHX: 102181869(MYH7) 106502520
ODA: 120853438(MYH6) 120853439
SSC: 100736765 396860(MYH7)
CFR: 102504269(MYH6) 102514829
CBAI: 105068782 105068784(MYH6)
BACU: 103014002(MYH7) 103020695(MYH6)
LVE: 103090453(MYH7) 103090716(MYH6)
OOR: 101290098(MYH7) 101290350(MYH6)
PSIU: 116748855(MYH6) 116748856
ECB: 111767446(MYH6) 791234(MYH7)
EAI: 106840636(MYH6) 123283050
MYB: 102249796(MYH7) 102250088(MYH6)
MYD: 102759546(MYH6) 102763864(MYH7)
MMYO: 118679048 118679049(MYH7)
MLF: 102442496(MYH7) 111828199
MNA: 107531658 107531708(MYH6)
PKL: 118725393
DRO: 112300691(MYH7) 112301295
SHON: 118980806 118980808(MYH7)
PDIC: 114491329(MYH7) 114491330
PHAS: 123820474(MYH6) 123820490
MMF: 118640544 118640553(MYH6)
RFQ: 117022948(MYH6) 117022949(MYH7)
PALE: 102879915(MYH7) 102880161
RAY: 107498010(MYH6) 107498011
MJV: 108400003
TOD: 119238070(MYH7) 119238932(MYH6)
SARA: 101546803(MYH6)
TMU: 101353289
DNM: 101427411 101442595(MYH7)
MDO: 100024758(MYH7) 100030608(MYH6)
SHR: 100925998 100935261(MYH6)
PCW: 110193568(MYH7) 110193748(MYH6)
OAA: 100088789 100089536(MYH6)
GGA: 395350(MYH7) 429272(MYO7L2)
FAB: 101807739 101809654(MYH7)
FPG: 101919808(MYH6)
EGZ: 104123279
AAM: 106484950
AROW: 112962297
NPD: 112956103
DNE: 112981979
AMJ: 102576117(MYH6)
CMY: 102948216
ACS: 100567487(myh7) 100567683
SUND: 121934760 121934761(MYH6)
PGUT: 117658223
XLA: 108707020 108714867(myh6.L) 108714868 432141(myh6.S)
XTR: 100216059(myh6) 100485637
NPR: 108786749(MYH7) 108786757
BBUF: 120989043
DRE: 100124599(smyhc2) 100329748 100329813 30616(myh7) 321552(smyhc1) 386711(myh6) 768300(myh7l)
SMEO: 124376779(myh6) 124402768
LCM: 102349723 102350257(MYH6)
CMK: 103173350
CIN: 100182775
APLC: 110980848
SKO: 100313659
DME: Dmel_CG17927(Mhc)
DER: 6547749
DSE: 6614425
DSI: Dsimw501_GD24080(Dsim_GD24080)
DYA: Dyak_GE12765(Dyak_Mhc)
DAN: 6498172
DSR: 110184857
DPE: 6589460
DMN: 108163265
DWI: 6643711
DGR: 6562444
DAZ: 108610128
DNV: 108649295
DHE: 111602527
DVI: 6627927
CCAT: 101455910
MDE: 101893508
SCAC: 106082291
LCQ: 111678371
ACOZ: 120956570
AARA: 120900587
CPII: 120424955
CNS: 116341384
AME: 409843
ACER: 107999930
ALAB: 122716932
BIM: 100744258
BBIF: 117207745
BVK: 117237014
BVAN: 117159928
BTER: 100647343
BPYO: 122570690
CCAL: 108622790
OBB: 114876930
MGEN: 117228886
NMEA: 116431853
CGIG: 122396455
SOC: 105201286
MPHA: 105835380
AEC: 105144318
ACEP: 105619195
PBAR: 105433414
VEM: 105570649
HST: 105191850
DQU: 106747433
CFO: 105249081
FEX: 115242911
LHU: 105673098
PGC: 109856373
OBO: 105283737
PFUC: 122514769
VPS: 122636634
NVI: 100123633
CSOL: 105368914
TPRE: 106655557
MDL: 103577568
CGLO: 123273034
FAS: 105262954
DAM: 107045995
AGIF: 122848892
CCIN: 107268743
TCA: 659358(Mhc1)
DPA: 109544441
SOY: 115879450
ATD: 109598056
CSET: 123316910
AGB: 108903445
LDC: 111511899
NVL: 108560030
APLN: 108734887
PPYR: 116178108
OTU: 111426781
BMOR: 100188972
BMAN: 114244973
MSEX: 115447480
BANY: 112057654
PMAC: 106709212
PPOT: 106107613
PXU: 106115455
PRAP: 111001269
ZCE: 119830898
HAW: 110379227
TNL: 113498905
OFU: 114358802
PXY: 105388810
API: 100167379
DNX: 107169832
AGS: 114126581
RMD: 113554970
BTAB: 109044765
DCI: 103512418
CLEC: 106664483
HHAL: 106684916
NLU: 111049488
FOC: 113201709
ZNE: 110833622
CSEC: 111865852
DMK: 116920186
HAZT: 108678476
DSV: 119453722
RSAN: 119399538
TUT: 107361059
DPTE: 113794921
DFR: 124494130
CEL: CELE_F11C3.3(unc-54) CELE_F58G4.1(myo-5) CELE_K12F2.1(myo-3) CELE_R06C7.10(myo-1) CELE_T18D3.4(myo-2)
CBR: CBG_00120(Cbr-myo-2) CBG_11357(Cbr-myo-5) CBG_19730(Cbr-unc-54) CBG_21911(Cbr-let-75) CBG_23416(Cbr-myo-3)
BMY: BM_BM11186(Bma-myo-3) BM_BM4116(Bm4116) BM_BM4560(Bma-myo-5)
PCAN: 112574048
BGT: 106056126
GAE: 121371733
PMAX: 117328884
OBI: 106872354(MYH)
OSN: 115225111
LAK: 106168235
EGL: EGR_03301
NVE: 5516909
EPA: 110239943
ADF: 107352751
AMIL: 114958645
PDAM: 113664641
SPIS: 111324002
DGT: 114528998
XEN: 124448399
HMG: 100205834
AQU: 100631811
 » show all
Reference
PMID:1776652
  Authors
Matsuoka R, Beisel KW, Furutani M, Arai S, Takao A
  Title
Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural and functional differences.
  Journal
Am J Med Genet 41:537-47 (1991)
DOI:10.1002/ajmg.1320410435
  Sequence
[hsa:4624]
Reference
PMID:2249844
  Authors
Jaenicke T, Diederich KW, Haas W, Schleich J, Lichter P, Pfordt M, Bach A, Vosberg HP
  Title
The complete sequence of the human beta-myosin heavy chain gene and a comparative analysis of its product.
  Journal
Genomics 8:194-206 (1990)
DOI:10.1016/0888-7543(90)90272-v
  Sequence
[hsa:4625]
Reference
  Authors
Berg JS, Powell BC, Cheney RE
  Title
A millennial myosin census.
  Journal
Mol Biol Cell 12:780-94 (2001)
DOI:10.1091/mbc.12.4.780
  Sequence

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