KEGG   ORTHOLOGY: K17832
Entry
K17832            Tight     KO                                     

Symbol
geoB
Name
geranial dehydrogenase [EC:1.2.1.86]
Pathway
map00281  Geraniol degradation
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00281 Geraniol degradation
    K17832  geoB; geranial dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.86  geranial dehydrogenase
     K17832  geoB; geranial dehydrogenase
Other DBs
RN: R08086
GO: 0034832
Genes
CDN: BN940_14181
Reference
  Authors
Luddeke F, Wulfing A, Timke M, Germer F, Weber J, Dikfidan A, Rahnfeld T, Linder D, Meyerdierks A, Harder J
  Title
Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans.
  Journal
Appl Environ Microbiol 78:2128-36 (2012)
DOI:10.1128/AEM.07226-11
  Sequence

KEGG   ENZYME: 1.2.1.86
Entry
EC 1.2.1.86                 Enzyme                                 

Name
geranial dehydrogenase;
GaDH;
geoB (gene name)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
geranial:NAD+ oxidoreductase
Reaction(IUBMB)
geranial + H2O + NAD+ = geranate + NADH + H+ [RN:R08086]
Reaction(KEGG)
R08086
Substrate
geranial [CPD:C01499];
H2O [CPD:C00001];
NAD+ [CPD:C00003]
Product
geranate [CPD:C16461];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Does not act on neral.
History
EC 1.2.1.86 created 2012
Pathway
ec00281  Geraniol degradation
ec01110  Biosynthesis of secondary metabolites
Orthology
K17832  geranial dehydrogenase
Genes
CDN: BN940_14181
Reference
1  [PMID:11778886]
  Authors
Wolken WA, van der Werf MJ.
  Title
Geraniol biotransformation-pathway in spores of Penicillium digitatum.
  Journal
Appl Microbiol Biotechnol 57:731-7 (2001)
DOI:10.1007/s002530100821
Reference
2  [PMID:22286981]
  Authors
Luddeke F, Wulfing A, Timke M, Germer F, Weber J, Dikfidan A, Rahnfeld T, Linder D, Meyerdierks A, Harder J
  Title
Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans.
  Journal
Appl Environ Microbiol 78:2128-36 (2012)
DOI:10.1128/AEM.07226-11
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.86
IUBMB Enzyme Nomenclature: 1.2.1.86
ExPASy - ENZYME nomenclature database: 1.2.1.86
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.86
BRENDA, the Enzyme Database: 1.2.1.86

KEGG   REACTION: R08086
Entry
R08086                      Reaction                               

Name
geranial:NAD+ oxidoreductase
Definition
Geranial + NAD+ + H2O <=> Geranic acid + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00218  C01499_C16461
Enzyme
Pathway
rn00281  Geraniol degradation
rn01110  Biosynthesis of secondary metabolites
Orthology
K17832  geranial dehydrogenase [EC:1.2.1.86]

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