KEGG   ORTHOLOGY: K18123
Entry
K18123                      KO                                     
Symbol
HOGA1
Name
4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16]
Pathway
map00330  Arginine and proline metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map01100  Metabolic pathways
Disease
H00117  Primary hyperoxaluria
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K18123  HOGA1; 4-hydroxy-2-oxoglutarate aldolase
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K18123  HOGA1; 4-hydroxy-2-oxoglutarate aldolase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.3  Oxo-acid-lyases
    4.1.3.16  4-hydroxy-2-oxoglutarate aldolase
     K18123  HOGA1; 4-hydroxy-2-oxoglutarate aldolase
Other DBs
RN: R00470 R00471
GO: 0008700
Genes
HSA: 112817(HOGA1)
PTR: 742884(HOGA1)
PPS: 103782784(HOGA1)
GGO: 101154009(HOGA1)
PON: 100171598(HOGA1)
NLE: 100589206(HOGA1)
MCC: 706661(HOGA1)
MCF: 102126728(HOGA1)
CSAB: 103216345(HOGA1)
CATY: 105581795(HOGA1)
PANU: 101014787(HOGA1)
TGE: 112631561(HOGA1)
RRO: 104682808(HOGA1)
RBB: 108534698(HOGA1)
TFN: 117068959(HOGA1)
PTEH: 111538766(HOGA1)
CJC: 103796777(HOGA1)
SBQ: 104650492(HOGA1)
CSYR: 103264836(HOGA1)
MMUR: 105873085(HOGA1)
LCAT: 123650168(HOGA1)
OGA: 100958797(HOGA1)
MMU: 67432(Hoga1)
MCAL: 110285310(Hoga1)
MPAH: 110333903(Hoga1)
RNO: 293949(Hoga1)
MCOC: 116103842(Hoga1)
MUN: 110564114(Hoga1)
CGE: 100759109(Hoga1)
MAUA: 101824115(Hoga1)
PLEU: 114706886(Hoga1)
MORG: 121454497(Hoga1)
AAMP: 119822156(Hoga1)
NGI: 103733196(Hoga1)
HGL: 101700602(Hoga1)
CPOC: 100720763(Hoga1)
CCAN: 109695304(Hoga1)
DORD: 105986751(Hoga1)
DSP: 122115913(Hoga1)
NCAR: 124984723
OCU: 100344505(HOGA1)
OPI: 101517296(HOGA1)
TUP: 102486364(HOGA1)
CFA: 608755(HOGA1)
VVP: 112914409(HOGA1)
VLG: 121483974(HOGA1)
AML: 100478059(HOGA1)
UMR: 103674087(HOGA1)
UAH: 113251791(HOGA1)
UAR: 123783886(HOGA1)
ELK: 111145298
LLV: 125084924
MPUF: 101693912(HOGA1)
ORO: 101385318(HOGA1)
EJU: 114205383(HOGA1)
ZCA: 113919122(HOGA1)
MLX: 118024504(HOGA1)
FCA: 101101417(HOGA1)
PYU: 121037065(HOGA1)
PBG: 122493090(HOGA1)
PTG: 102965487(HOGA1)
PPAD: 109272717(HOGA1)
AJU: 106966929(HOGA1)
HHV: 120230623(HOGA1)
BTA: 506001(HOGA1)
BOM: 102265621(HOGA1)
BIU: 109552999(HOGA1)
BBUB: 102398601(HOGA1)
CHX: 102173994(HOGA1)
OAS: 101114573(HOGA1)
ODA: 120873942(HOGA1)
CCAD: 122446094(HOGA1)
SSC: 100153961(HOGA1)
CFR: 102512614(HOGA1)
CBAI: 105081776(HOGA1)
CDK: 105084288(HOGA1)
VPC: 102541568(HOGA1)
BACU: 103004258(HOGA1)
LVE: 103077167 103089444(HOGA1)
OOR: 101271753(HOGA1)
DLE: 111172427(HOGA1)
PCAD: 102979032(HOGA1)
PSIU: 116741875(HOGA1)
ECB: 100070689(HOGA1)
EPZ: 103558701(HOGA1)
EAI: 106844960(HOGA1)
MYB: 102246939(HOGA1)
MYD: 102768587(HOGA1)
MMYO: 118669893(HOGA1)
MLF: 102427524(HOGA1)
MNA: 107542604(HOGA1)
PKL: 118719357(HOGA1)
HAI: 109379716(HOGA1)
DRO: 112307109(HOGA1)
SHON: 118990274(HOGA1)
AJM: 119044532(HOGA1)
PDIC: 114495945(HOGA1)
PHAS: 123828952(HOGA1)
MMF: 118632358(HOGA1)
RFQ: 117036234(HOGA1)
PALE: 102884382(HOGA1)
PGIG: 120609240(HOGA1)
PVP: 105301380(HOGA1)
RAY: 107520438(HOGA1)
MJV: 108399750(HOGA1)
TOD: 119233797(HOGA1)
LAV: 100670230(HOGA1)
TMU: 101355404
DNM: 101419181(HOGA1)
MDO: 100021876(HOGA1)
GAS: 123238246(HOGA1)
SHR: 100929176(HOGA1)
PCW: 110215427(HOGA1)
OAA: 100088274(HOGA1)
GGA: 770036(HOGA1)
PCOC: 116231725(HOGA1)
MGP: 100548398(HOGA1)
CJO: 107316003(HOGA1)
NMEL: 110400352(HOGA1)
ACYG: 106036839(HOGA1)
AFUL: 116491080(HOGA1)
TGU: 100231472(HOGA1)
LSR: 110473597(HOGA1)
SCAN: 103813888(HOGA1)
PMOA: 120502206(HOGA1)
OTC: 121341648(HOGA1)
PRUF: 121350021(HOGA1)
GFR: 102042170(HOGA1)
FAB: 101806953(HOGA1)
PHI: 102112987(HOGA1)
PMAJ: 107206698(HOGA1)
CCAE: 111931229(HOGA1)
CCW: 104695887(HOGA1)
ETL: 114070777(HOGA1)
ZAB: 102062750(HOGA1)
FPG: 101920952(HOGA1)
FCH: 102052298(HOGA1)
CLV: 102097409(HOGA1)
EGZ: 104132255(HOGA1)
NNI: 104012772(HOGA1)
PLET: 104621767(HOGA1)
ACUN: 113481407(HOGA1)
TALA: 116962067(HOGA1)
PADL: 103916280(HOGA1)
ACHC: 115348491(HOGA1)
AROW: 112968046(HOGA1)
NPD: 112957175(HOGA1)
DNE: 112984791(HOGA1)
ASN: 102382587(HOGA1)
AMJ: 102563093(HOGA1)
CPOO: 109324348(HOGA1)
GGN: 109287532(HOGA1)
CMY: 114018236(HOGA1)
CPIC: 103307603(HOGA1)
TST: 117880415(HOGA1)
CABI: 116822802(HOGA1)
ACS: 100566929(hoga1)
PVT: 110089167(HOGA1)
SUND: 121926128(HOGA1)
PBI: 103053263(HOGA1)
PMUR: 107295219(HOGA1)
TSR: 106549035(HOGA1)
PGUT: 117678595(HOGA1)
VKO: 123026676(HOGA1)
PMUA: 114597588(HOGA1)
ZVI: 118093538(HOGA1)
GJA: 107114457(HOGA1)
STOW: 125438115(HOGA1)
XLA: 495193(hoga1.L)
XTR: 496669(hoga1)
NPR: 108792933(HOGA1)
RTEM: 120946635(HOGA1)
BBUF: 121004610(HOGA1)
DRE: 405806(hoga1)
SRX: 107706114
SANH: 107663482(hoga1)
SGH: 107551368 107588470(hoga1)
CCAR: 109069442
CAUA: 113039744(hoga1)
PPRM: 120468726 120468763(hoga1)
MAMB: 125254424(hoga1)
IPU: 108259603(hoga1)
PHYP: 113546731(hoga1)
SMEO: 124379684(hoga1)
TFD: 113656985(hoga1)
AMEX: 103023796(hoga1)
EEE: 113577699(hoga1)
TRU: 101061435(hoga1)
LCO: 104930035(hoga1)
NCC: 104953008(hoga1)
ELY: 117255225(hoga1)
SLUC: 116049892(hoga1)
ECRA: 117962147(hoga1)
PFLV: 114570716(hoga1)
GAT: 120813082(hoga1)
PPUG: 119218010(hoga1)
MSAM: 119898305(hoga1)
CUD: 121508633(hoga1)
ALAT: 119019204(hoga1)
MZE: 101479315(hoga1)
ONL: 100690946(hoga1)
OAU: 116315581(hoga1)
OLA: 101161460(hoga1)
OML: 112156927(hoga1)
XMA: 102230783(hoga1)
XCO: 114145238(hoga1)
XHE: 116720256(hoga1)
PRET: 103470116(hoga1)
PFOR: 103154489(hoga1)
PLAI: 106948744(hoga1)
PMEI: 106927085(hoga1)
GAF: 122830294(hoga1)
CVG: 107081958(hoga1)
CTUL: 119798502(hoga1)
GMU: 124869120(hoga1)
NFU: 107382406(hoga1)
KMR: 108247450(hoga1)
ALIM: 106537034(hoga1)
AOCE: 111580411(hoga1)
CSEM: 103383203(hoga1)
POV: 109645371
SSEN: 122771614(hoga1)
HHIP: 117760502(hoga1)
HSP: 118099088(hoga1)
LCF: 108880833(hoga1)
SDU: 111235845(hoga1)
SLAL: 111665639(hoga1)
XGL: 120800280(hoga1)
HCQ: 109511381(hoga1)
BPEC: 110155940(hoga1)
MALB: 109952000(hoga1)
BSPL: 114861357(hoga1)
SASA: 106591168(hoga1) 106591313
OTW: 112230192(hoga1)
OGO: 124018276(hoga1)
ONE: 115127679(hoga1)
SALP: 112079381(hoga1)
SNH: 120032829(hoga1) 120032838
ELS: 105006876(hoga1)
SFM: 108924852(hoga1)
PKI: 111848362(hoga1)
AANG: 118219744(hoga1)
LOC: 102687344(hoga1)
PSPA: 121321919(hoga1)
ARUT: 117415418(hoga1)
LCM: 102362318(HOGA1)
CMK: 103172525(hoga1)
RTP: 109921722(hoga1)
BBEL: 109485298
CIN: 100181036
SCLV: 120331743
SPU: 579934
APLC: 110981286
SKO: 100372772
BCOO: 119068060
API: 100570569
DNX: 107163989
AGS: 114132054
RMD: 113549091
HHAL: 106681743
NLU: 111064155
ZNE: 110831450
CSEC: 111864684
FCD: 110856855
DMK: 116921690
PVM: 113818492
PJA: 122267255
PCHN: 125038676
HAME: 121871046
PCLA: 123774790
PTRU: 123517476
HAZT: 108672513
EAF: 111698923
PPOI: 119112206
DSV: 119442461
RSAN: 119388374
RMP: 119159482
CSCU: 111618478
PTEP: 107438884
SDM: 118202582
PCAN: 112565420
BGT: 106072266
GAE: 121383851
HRF: 124138672
HRJ: 124264316
CRG: 105328725
MYI: 110455405
PMAX: 117339557
MMER: 123547812
OBI: 106884306
OSN: 115232061
LAK: 106170963
NVE: 5520994
EPA: 110231654
ATEN: 116307006
ADF: 107337820
AMIL: 114962597
PDAM: 113686876
SPIS: 111324439
DGT: 114515751
XEN: 124444846
HMG: 100199549
QSU: 111991330
NTE: NEUTE1DRAFT148948(NEUTE1DRAFT_148948) NEUTE1DRAFT48910(NEUTE1DRAFT_48910)
MBE: MBM_05778
ANI: AN1503.2
ANG: ANI_1_1446134(An15g04230) ANI_1_1986144(An16g07700) ANI_1_26174(An10g00330)
CNE: CNC03990
CNB: CNBC3190
TASA: A1Q1_07016
ABP: AGABI1DRAFT111212(AGABI1DRAFT_111212) AGABI1DRAFT114952(AGABI1DRAFT_114952)
ABV: AGABI2DRAFT190432(AGABI2DRAFT_190432) AGABI2DRAFT191181(AGABI2DRAFT_191181)
LIP: LI0108(dapA)
LIR: LAW_00107(dapA_1)
DHD: Dhaf_1978
TFR: BR63_09785(dapA)
TMR: Tmar_1165
THX: Thet_1017
TIT: Thit_1575
KME: H0A61_00412(dapA_2)
STI: Sthe_0488
TRA: Trad_0621
TSC: TSC_c08910(dapA1)
MRB: Mrub_2327
LCRE: Pla8534_42110(dapA_3)
ACA: ACP_0327
ABAS: ACPOL_6664
SUS: Acid_1067
ABAC: LuPra_06084(dapA_3)
TLI: Tlie_1310
GAU: GAU_0904
GBA: J421_2804
 » show all
Reference
  Authors
Riedel TJ, Johnson LC, Knight J, Hantgan RR, Holmes RP, Lowther WT
  Title
Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria.
  Journal
PLoS One 6:e26021 (2011)
DOI:10.1371/journal.pone.0026021
  Sequence
[hsa:112817]

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